ATP binding to the pseudokinase domain of JAK2 is critical for pathogenic activation
Hammarén, Henrik M., Ungureanu, Daniela, Grisouard, Jean, Skoda, Radek C., Hubbard, Stevan R., Silvennoinen, Olli
Published in Proceedings of the National Academy of Sciences - PNAS (14.04.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (14.04.2015)
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Journal Article
Deletion of Stat3 in hematopoietic cells enhances thrombocytosis and shortens survival in a JAK2-V617F mouse model of MPN
Grisouard, Jean, Shimizu, Takafumi, Duek, Adrian, Kubovcakova, Lucia, Hao-Shen, Hui, Dirnhofer, Stephan, Skoda, Radek C.
Published in Blood (26.03.2015)
Published in Blood (26.03.2015)
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Journal Article
Analysis of signaling pathways related to cell proliferation stimulated by insulin analogs in human mammary epithelial cell lines
Shukla, Ashish, Grisouard, Jean, Ehemann, Volker, Hermani, Alexander, Enzmann, Harald, Mayer, Doris
Published in Endocrine-related cancer (01.06.2009)
Published in Endocrine-related cancer (01.06.2009)
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Journal Article
Glucose-dependent insulinotropic polypeptide induces cytokine expression, lipolysis, and insulin resistance in human adipocytes
Timper, Katharina, Grisouard, Jean, Sauter, Nadine S, Herzog-Radimerski, Tanja, Dembinski, Kaethi, Peterli, Ralph, Frey, Daniel M, Zulewski, Henryk, Keller, Ulrich, Müller, Beat, Christ-Crain, Mirjam
Published in American journal of physiology: endocrinology and metabolism (01.01.2013)
Published in American journal of physiology: endocrinology and metabolism (01.01.2013)
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Journal Article
Loss of Stat1 decreases megakaryopoiesis and favors erythropoiesis in a JAK2-V617F–driven mouse model of MPNs
Duek, Adrian, Lundberg, Pontus, Shimizu, Takafumi, Grisouard, Jean, Karow, Axel, Kubovcakova, Lucia, Hao-Shen, Hui, Dirnhofer, Stephan, Skoda, Radek C.
Published in Blood (19.06.2014)
Published in Blood (19.06.2014)
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Journal Article
Targeting AMP-activated protein kinase in adipocytes to modulate obesity-related adipokine production associated with insulin resistance and breast cancer cell proliferation
Grisouard, Jean, Dembinski, Kaethi, Mayer, Doris, Keller, Ulrich, Müller, Beat, Christ-Crain, Mirjam
Published in Diabetology and metabolic syndrome (20.07.2011)
Published in Diabetology and metabolic syndrome (20.07.2011)
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Journal Article
JAK2 exon 12 mutant mice display isolated erythrocytosis and changes in iron metabolism favoring increased erythropoiesis
Grisouard, Jean, Li, Sai, Kubovcakova, Lucia, Rao, Tata Nageswara, Meyer, Sara C., Lundberg, Pontus, Hao-Shen, Hui, Romanet, Vincent, Murakami, Masato, Radimerski, Thomas, Dirnhofer, Stephan, Skoda, Radek C.
Published in Blood (11.08.2016)
Published in Blood (11.08.2016)
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Journal Article
Glycogen Synthase Kinase-3 Protects Estrogen Receptor α from Proteasomal Degradation and Is Required for Full Transcriptional Activity of the Receptor
Grisouard, Jean, Medunjanin, Senad, Hermani, Alexander, Shukla, Ashish, Mayer, Doris
Published in Molecular endocrinology (Baltimore, Md.) (01.10.2007)
Published in Molecular endocrinology (Baltimore, Md.) (01.10.2007)
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Journal Article
Differential effects of hydroxyurea and INC424 on mutant allele burden and myeloproliferative phenotype in a JAK2-V617F polycythemia vera mouse model
Kubovcakova, Lucia, Lundberg, Pontus, Grisouard, Jean, Hao-Shen, Hui, Romanet, Vincent, Andraos, Rita, Murakami, Masato, Dirnhofer, Stephan, Wagner, Kay-Uwe, Radimerski, Thomas, Skoda, Radek C.
Published in Blood (14.02.2013)
Published in Blood (14.02.2013)
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Journal Article
Mechanisms of metformin action on glucose transport and metabolism in human adipocytes
Grisouard, Jean, Timper, Katharina, Radimerski, Tanja M., Frey, Daniel M., Peterli, Ralph, Kola, Blerina, Korbonits, Márta, Herrmann, Paul, Krähenbühl, Stephan, Zulewski, Henryk, Keller, Ulrich, Müller, Beat, Christ-Crain, Mirjam
Published in Biochemical pharmacology (01.12.2010)
Published in Biochemical pharmacology (01.12.2010)
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Journal Article
Glycogen Synthase Kinase-3 Interacts with and Phosphorylates Estrogen Receptor α and Is Involved in the Regulation of Receptor Activity
Medunjanin, Senad, Hermani, Alexander, De Servi, Barbara, Grisouard, Jean, Rincke, Gabriele, Mayer, Doris
Published in The Journal of biological chemistry (23.09.2005)
Published in The Journal of biological chemistry (23.09.2005)
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Journal Article
Complex subclone structure that responds differentially to therapy in a patient with essential thrombocythemia and chronic myeloid leukemia
Grisouard, Jean, Ojeda-Uribe, Mario, Looser, Renate, Hao-Shen, Hui, Lundberg, Pontus, Duek, Adrian, Jeandidier, Eric, Karow, Axel, Skoda, Radek C.
Published in Blood (21.11.2013)
Published in Blood (21.11.2013)
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Journal Article
JAK2V617F and Loss of Ezh2 in Hematopoietic Cells Contribute Synergistically to Myeloproliferative Neoplasm Initiation Potential, and Accelerate Progression of Disease
Shimizu, Takafumi, Hao-Shen, Hui, Kubovcakova, Lucia, Lundberg, Pontus, Dirnhofer, Stephan, Orkin, Stuart H., Grisouard, Jean, Shimizu, Yukiko, Pianta, Annalisa, Szczerba, Barbara, Nienhold, Ronny, Skoda, Radek C.
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Journal Article
Both inflammatory and classical lipolytic pathways are involved in lipopolysaccharide-induced lipolysis in human adipocytes
Grisouard, Jean, Bouillet, Elisa, Timper, Katharina, Radimerski, Tanja, Dembinski, Kaethi, Frey, Daniel M, Peterli, Ralph, Zulewski, Henryk, Keller, Ulrich, Müller, Beat, Christ-Crain, Mirjam
Published in Innate immunity (London, England) (01.02.2012)
Published in Innate immunity (London, England) (01.02.2012)
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Journal Article
Glucose-Dependent Insulinotropic Polypeptide (GIP) Induces Calcitonin Gene-Related Peptide (CGRP)-I and Procalcitonin (Pro-CT) Production in Human Adipocytes
Timper, Katharina, Grisouard, Jean, Radimerski, Tanja, Dembinski, Kaethi, Peterli, Ralph, Häring, Andreas, Frey, Daniel M, Zulewski, Henryk, Keller, Ulrich, Müller, Beat, Christ-Crain, Mirjam
Published in The journal of clinical endocrinology and metabolism (01.02.2011)
Published in The journal of clinical endocrinology and metabolism (01.02.2011)
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Journal Article
Glucose-dependent insulinotropic polypeptide induces cytokine expression, lipolysis, and insulin resistance in human adipocytes
TIMPER, Katharina, GRISOUARD, Jean, CHRIST-CRAIN, Mirjam, SAUTER, Nadine S, HERZOG-RADIMERSKI, Tanja, DEMBINSKI, Kaethi, PETERLI, Ralph, FREY, Daniel M, ZULEWSKI, Henryk, KELLER, Ulrich, MÜLLER, Beat
Published in American journal of physiology: endocrinology and metabolism (2013)
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Published in American journal of physiology: endocrinology and metabolism (2013)
Journal Article
Role of calcium in lipopolysaccharide-induced calcitonin gene expression in human adipocytes
Radimerski, Tanja M, Grisouard, Jean, Timper, Katharina, Zulewski, Henryk, Christ-Crain, Mirjam, Keller, Ulrich, Müller, Beat
Published in Innate immunity (London, England) (01.08.2011)
Published in Innate immunity (London, England) (01.08.2011)
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