STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression
Balic, Jesse J., Albargy, Hassan, Luu, Kevin, Kirby, Francis J., Jayasekara, W. Samantha N., Mansell, Finbar, Garama, Daniel J., De Nardo, Dominic, Baschuk, Nikola, Louis, Cynthia, Humphries, Fiachra, Fitzgerald, Katherine, Latz, Eicke, Gough, Daniel J., Mansell, Ashley
Published in Nature communications (30.07.2020)
Published in Nature communications (30.07.2020)
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Journal Article
Trp53 and Rb1 regulate autophagy and ligand-dependent Hedgehog signaling
Cochrane, Catherine R, Vaghjiani, Vijesh, Szczepny, Anette, Jayasekara, W Samantha N, Gonzalez-Rajal, Alvaro, Kikuchi, Kazu, McCaughan, Geoffrey W, Burgess, Andrew, Gough, Daniel J, Watkins, D Neil, Cain, Jason E
Published in The Journal of clinical investigation (01.08.2020)
Published in The Journal of clinical investigation (01.08.2020)
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ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma
Jackson, Evangeline R, Duchatel, Ryan J, Staudt, Dilana E, Persson, Mika L, Mannan, Abdul, Yadavilli, Sridevi, Parackal, Sarah, Game, Shaye, Chong, Wai Chin, Jayasekara, W Samantha Nilanthi, Le Grand, Marion, Kearney, Padraic S, Douglas, Alicia M, Findlay, Izac J, Germon, Zacary P, McEwen, Holly P, Beitaki, Tyrone S, Patabendige, Adjanie, Skerrett-Byrne, David A, Nixon, Brett, Smith, Nathan D, Day, Bryan, Manoharan, Neevika, Nagabushan, Sumanth, Hansford, Jordan R, Govender, Dinisha, McCowage, Geoffrey B, Firestein, Ron, Howlett, Meegan, Endersby, Raelene, Gottardo, Nicholas G, Alvaro, Frank, Waszak, Sebastian M, Larsen, Martin R, Colino-Sanguino, Yolanda, Valdés-Mora, Fatima, Rakotomalala, Andria, Meignan, Samuel, Pasquier, Eddy, Andre, Nicolas, Hulleman, Esther, Eisenstat, David D, Vitanza, Nicholas A, Nazarian, Javad, Koschmann, Carl, Mueller, Sabine, Cain, Jason E, Dun, Matthew D
Published in Cancer research (Chicago, Ill.) (05.05.2023)
Published in Cancer research (Chicago, Ill.) (05.05.2023)
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Lineage-restricted neoplasia driven by Myc defaults to small cell lung cancer when combined with loss of p53 and Rb in the airway epithelium
Chen, Jasmine, Guanizo, Aleks, Luong, Quinton, Jayasekara, W. Samantha N., Jayasinghe, Dhilshan, Inampudi, Chaitanya, Szczepny, Anette, Garama, Daniel J., Russell, Prudence A., Ganju, Vinod, Cain, Jason E., Watkins, D. Neil, Gough, Daniel J.
Published in Oncogene (03.01.2022)
Published in Oncogene (03.01.2022)
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Journal Article
The degree of mitochondrial DNA methylation in tumor models of glioblastoma and osteosarcoma
Sun, Xin, Vaghjiani, Vijesh, Jayasekara, W Samantha N, Cain, Jason E, St John, Justin C
Published in Clinical epigenetics (17.12.2018)
Published in Clinical epigenetics (17.12.2018)
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Journal Article
Genomic characterisation of small cell lung cancer patient-derived xenografts generated from endobronchial ultrasound-guided transbronchial needle aspiration specimens
Leong, Tracy L, Marini, Kieren D, Rossello, Fernando J, Jayasekara, Samantha N, Russell, Prudence A, Prodanovic, Zdenka, Kumar, Beena, Ganju, Vinod, Alamgeer, Muhammad, Irving, Louis B, Steinfort, Daniel P, Peacock, Craig D, Cain, Jason E, Szczepny, Anette, Watkins, D Neil
Published in PloS one (05.09.2014)
Published in PloS one (05.09.2014)
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Journal Article
The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53
Szczepny, Anette, Carey, Kirstyn, McKenzie, Lisa, Jayasekara, W. Samantha N., Rossello, Fernando, Gonzalez-Rajal, Alvaro, McCaw, Andrew S., Popovski, Dean, Wang, Die, Sadler, Anthony J., Mahar, Annabelle, Russell, Prudence A., Wright, Gavin, McCloy, Rachael A., Garama, Daniel J., Gough, Daniel J., Baylin, Stephen B., Burgess, Andrew, Cain, Jason E., Watkins, D. Neil
Published in Oncogene (01.04.2018)
Published in Oncogene (01.04.2018)
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Journal Article
Ligand-dependent hedgehog signaling maintains an undifferentiated, malignant osteosarcoma phenotype
Vaghjiani, Vijesh G., Cochrane, Catherine R., Jayasekara, W. Samantha N., Chong, Wai Chin, Szczepny, Anette, Kumar, Beena, Martelotto, Luciano G., McCaw, Andrew, Carey, Kirstyn, Kansara, Maya, Thomas, David M., Walkley, Carl, Mudge, Stuart, Gough, Daniel J., Downie, Peter A., Peacock, Craig D., Matsui, William, Watkins, D. Neil, Cain, Jason E.
Published in Oncogene (17.11.2023)
Published in Oncogene (17.11.2023)
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Journal Article
Cre-dependent DNA recombination activates a STING-dependent innate immune response
Pépin, Geneviève, Ferrand, Jonathan, Höning, Klara, Jayasekara, W Samantha N, Cain, Jason E, Behlke, Mark A, Gough, Daniel J, G Williams, Bryan R, Hornung, Veit, Gantier, Michael P
Published in Nucleic acids research (20.06.2016)
Published in Nucleic acids research (20.06.2016)
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Journal Article
A STAT3 protein complex required for mitochondrial mRNA stability and cancer
Fernando, C. Dilanka, Jayasekara, W. Samantha N., Inampudi, Chaitanya, Kohonen-Corish, Maija R.J., Cooper, Wendy A., Beilharz, Traude H., Josephs, Tracy M., Garama, Daniel J., Gough, Daniel J.
Published in Cell reports (Cambridge) (26.09.2023)
Published in Cell reports (Cambridge) (26.09.2023)
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Pharmacological inhibition of TBK1/IKKε blunts immunopathology in a murine model of SARS-CoV-2 infection
Ullah, Tomalika R., Johansen, Matt D., Balka, Katherine R., Ambrose, Rebecca L., Gearing, Linden J., Roest, James, Vivian, Julian P., Sapkota, Sunil, Jayasekara, W. Samantha N., Wenholz, Daniel S., Aldilla, Vina R., Zeng, Jun, Miemczyk, Stefan, Nguyen, Duc H., Hansbro, Nicole G., Venkatraman, Rajan, Kang, Jung Hee, Pang, Ee Shan, Thomas, Belinda J., Alharbi, Arwaf S., Rezwan, Refaya, O’Keeffe, Meredith, Donald, William A., Ellyard, Julia I., Wong, Wilson, Kumar, Naresh, Kile, Benjamin T., Vinuesa, Carola G., Kelly, Graham E., Laczka, Olivier F., Hansbro, Philip M., De Nardo, Dominic, Gantier, Michael P.
Published in Nature communications (18.09.2023)
Published in Nature communications (18.09.2023)
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Journal Article
Low-Dose Histone Deacetylase Inhibitor Treatment Leads to Tumor Growth Arrest and Multi-Lineage Differentiation of Malignant Rhabdoid Tumors
Muscat, Andrea, Popovski, Dean, Jayasekara, W Samantha N, Rossello, Fernando J, Ferguson, Melissa, Marini, Kieren D, Alamgeer, Muhammad, Algar, Elizabeth M, Downie, Peter, Watkins, D Neil, Cain, Jason E, Ashley, David M
Published in Clinical cancer research (15.07.2016)
Published in Clinical cancer research (15.07.2016)
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Journal Article
Deep multi-region whole-genome sequencing reveals heterogeneity and gene-by-environment interactions in treatment-naive, metastatic lung cancer
Leong, Tracy L., Gayevskiy, Velimir, Steinfort, Daniel P., De Massy, Marc R., Gonzalez-Rajal, Alvaro, Marini, Kieren D., Stone, Emily, Chin, Venessa, Havryk, Adrian, Plit, Marshall, Irving, Louis B., Jennings, Barton R., McCloy, Rachael A., Jayasekara, W. Samantha N., Alamgeer, Muhammad, Boolell, Vishal, Field, Andrew, Russell, Prudence A., Kumar, Beena, Gough, Daniel J., Szczepny, Anette, Ganju, Vinod, Rossello, Fernando J., Cain, Jason E., Papenfuss, Anthony T., Asselin-Labat, Marie-Liesse, Cowley, Mark J., Watkins, D. Neil
Published in Oncogene (01.03.2019)
Published in Oncogene (01.03.2019)
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Journal Article
Inhibition of activin signaling in lung adenocarcinoma increases the therapeutic index of platinum chemotherapy
Marini, Kieren D, Croucher, David R, McCloy, Rachael A, Vaghjiani, Vijesh, Gonzalez-Rajal, Alvaro, Hastings, Jordan F, Chin, Venessa, Szczepny, Anette, Kostyrko, Kaja, Marquez, Cesar, Jayasekara, W Samantha N, Alamgeer, Muhammad, Boolell, Vishal, Han, Jeremy Z R, Waugh, Todd, Lee, Hong Ching, Oakes, Samantha R, Kumar, Beena, Harrison, Craig A, Hedger, Mark P, Lorensuhewa, Nirmal, Kita, Badia, Barrow, Ross, Robinson, Bruce W, de Kretser, David M, Wu, Jianmin, Ganju, Vinod, Sweet-Cordero, E Alejandro, Burgess, Andrew, Martelotto, Luciano G, Rossello, Fernando J, Cain, Jason E, Watkins, D Neil
Published in Science translational medicine (25.07.2018)
Published in Science translational medicine (25.07.2018)
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Journal Article
A Sexually Dimorphic Role for STAT3 in Sonic Hedgehog Medulloblastoma
White, Christine L, Jayasekara, W Samantha N, Picard, Daniel, Chen, Jasmine, Watkins, D Neil, Cain, Jason E, Remke, Marc, Gough, Daniel J
Published in Cancers (01.11.2019)
Published in Cancers (01.11.2019)
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Journal Article
Atypical Teratoid Rhabdoid Tumours Are Susceptible to Panobinostat-Mediated Differentiation Therapy
Chong, Wai C., Jayasekara, W. Samantha N., Vaghjiani, Vijesh G., Parackal, Sarah, Sun, Claire, Popovski, Dean, Algar, Elizabeth M., Firestein, Ron, Wood, Paul J., Khan, Sara, Huang, Annie, Ashley, David M., Downie, Peter, Cain, Jason E.
Published in Cancers (14.10.2021)
Published in Cancers (14.10.2021)
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Journal Article
Sustained Low-Dose Treatment with the Histone Deacetylase Inhibitor LBH589 Induces Terminal Differentiation of Osteosarcoma Cells
Watkins, D. Neil, Ashley, David M., Kansara, Maya, Irving, Aaron T., Marini, Kieren D., Rossello, Fernando J., Jayasekara, W. Samantha N., McCaw, Andrew, Cain, Jason E., Thomas, David M.
Published in Complexity (New York, N.Y.) (2013)
Published in Complexity (New York, N.Y.) (2013)
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Journal Article
The mouse endometrium contains epithelial, endothelial and leucocyte populations expressing the stem cell marker telomerase reverse transcriptase
Deane, James A, Ong, Y Rue, Cain, Jason E, Jayasekara, W Samantha N, Tiwari, Abhilasha, Carlone, Diana L, Watkins, D Neil, Breault, David T, Gargett, Caroline E
Published in Molecular human reproduction (01.04.2016)
Published in Molecular human reproduction (01.04.2016)
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Journal Article
Abstract 3029: Functional genomics pipeline reveals therapeutic dependencies in diffuse intrinsic pontine glioma
Parackal, Sarah, Bradshaw, Gabrielle, Sun, Claire, Chong, Wai Chin, Daniel, Paul, Jayasekara, Samantha, Crombie, Duncan, Firestein, Ron, Cain, Jason
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Expression and Possible Role of 20α-Hydroxysteroid Dehydrogenase in the Placenta of the Goat
JAYASEKARA, Walimuni Samantha Nilanthi, YONEZAWA, Tomohiro, ISHIDA, Maho, YAMANOUCHI, Keitaro, NISHIHARA, Masugi
Published in Journal of Reproduction and Development (01.04.2005)
Published in Journal of Reproduction and Development (01.04.2005)
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