Alternatives to rifampicin: A review and perspectives on the choice of strong CYP3A inducers for clinical drug–drug interaction studies
Bolleddula, Jayaprakasam, Gopalakrishnan, Sathej, Hu, Ping, Dong, Jennifer, Venkatakrishnan, Karthik
Published in Clinical and translational science (01.09.2022)
Published in Clinical and translational science (01.09.2022)
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Journal Article
PBPK modeling to predict drug‐drug interactions of ivosidenib as a perpetrator in cancer patients and qualification of the Simcyp platform for CYP3A4 induction
Bolleddula, Jayaprakasam, Ke, Alice, Yang, Hua, Prakash, Chandra
Published in CPT: pharmacometrics and systems pharmacology (01.06.2021)
Published in CPT: pharmacometrics and systems pharmacology (01.06.2021)
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Journal Article
Phase I study assessing the mass balance, pharmacokinetics, and excretion of [14C]-pevonedistat, a NEDD8-activating enzyme inhibitor in patients with advanced solid tumors
Zhou, Xiaofei, Sedarati, Farhad, Faller, Douglas V., Zhao, Dan, Faessel, Hélène M., Chowdhury, Swapan, Bolleddula, Jayaprakasam, Li, Yuexian, Venkatakrishnan, Karthik, Papai, Zsuzsanna
Published in Investigational new drugs (01.04.2021)
Published in Investigational new drugs (01.04.2021)
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Journal Article
Asia‐inclusive drug development leveraging principles of ICH E5 and E17 guidelines: Case studies illustrating quantitative clinical pharmacology as a foundational enabler
Lu, Hong, Klopp‐Schulze, Lena, Mukker, Jatinder Kaur, Li, Dandan, Kuroki, Yoshihiro, Bolleddula, Jayaprakasam, Terranova, Nadia, Goteti, Kosalaram, Gao, Wei, Strotmann, Rainer, Dong, Jennifer, Venkatakrishnan, Karthik
Published in Clinical and translational science (01.10.2024)
Published in Clinical and translational science (01.10.2024)
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Journal Article
Withanolides potentiate apoptosis, inhibit invasion, and abolish osteoclastogenesis through suppression of nuclear factor-κB (NF-κB) activation and NF-κB–regulated gene expression
Ichikawa, Haruyo, Takada, Yasunari, Shishodia, Shishir, Jayaprakasam, Bolleddula, Nair, Muraleedharan G., Aggarwal, Bharat B.
Published in Molecular cancer therapeutics (01.06.2006)
Published in Molecular cancer therapeutics (01.06.2006)
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Journal Article
Amelioration of Obesity and Glucose Intolerance in High-Fat-Fed C57BL/6 Mice by Anthocyanins and Ursolic Acid in Cornelian Cherry (Cornus mas)
Jayaprakasam, Bolleddula, Olson, L. Karl, Schutzki, Robert E, Tai, Mei-Hui, Nair, Muraleedharan G
Published in Journal of agricultural and food chemistry (11.01.2006)
Published in Journal of agricultural and food chemistry (11.01.2006)
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Journal Article
Regulation of hepatic fatty acid elongase and desaturase expression in diabetes and obesity
Wang, Yun, Botolin, Daniela, Xu, Jinghua, Christian, Barbara, Mitchell, Ernestine, Jayaprakasam, Bolleddula, Nair, Muraleedharan, Peters, Jeffery M., Busik, Julia, Olson, L. Karl, Jump, Donald B.
Published in Journal of lipid research (01.09.2006)
Published in Journal of lipid research (01.09.2006)
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Journal Article
Impact of Alkyl Esters of Caffeic and Ferulic Acids on Tumor Cell Proliferation, Cyclooxygenase Enzyme, and Lipid Peroxidation
Jayaprakasam, Bolleddula, Vanisree, Mulabagal, Zhang, Yanjun, Dewitt, David L, Nair, Muraleedharan G
Published in Journal of agricultural and food chemistry (26.07.2006)
Published in Journal of agricultural and food chemistry (26.07.2006)
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Journal Article
Growth inhibition of human tumor cell lines by withanolides from Withania somnifera leaves
Jayaprakasam, Bolleddula, Zhang, Yanjun, Seeram, Navindra P, Nair, Muraleedharan G
Published in Life sciences (1973) (21.11.2003)
Published in Life sciences (1973) (21.11.2003)
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Journal Article
Anticancer and antiinflammatory activities of cucurbitacins from Cucurbita andreana
JAYAPRAKASAM, Bolleddula, SEERAM, Navindra P, NAIR, Muraleedharan G
Published in Cancer letters (10.01.2003)
Published in Cancer letters (10.01.2003)
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Journal Article
In vitro and in vivo catabolism of TAK-164, a gcc-targeted antibody-drug conjugate
Bolleddula, Jayaprakasam, Shadid, Mohammad, Shah, Abhi, Kamali, Afrand, Smith, Mike, Abu-Yousif, Adnan, Xia, Cindy, Chowdhury, Swapan K.
Published in Drug metabolism and pharmacokinetics (01.01.2019)
Published in Drug metabolism and pharmacokinetics (01.01.2019)
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Journal Article
Steryl epoxide, secobutanolide and butanolides from the stem wood of Machilus zuihoensis
Cheng, Ming-Jen, Tsai, Ian-Lih, Lee, Shoiw-Ju, Jayaprakasam, Bolleddula, Chen, Ih-Sheng
Published in Phytochemistry (Oxford) (01.05.2005)
Published in Phytochemistry (Oxford) (01.05.2005)
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Journal Article
Chemical and cytotoxic constituents from Peperomia sui
Cheng, Ming-Jen, Lee, Shoiw-Ju, Chang, Ying-Ying, Wu, Szu-Huei, Tsai, Ian-Lih, Jayaprakasam, Bolleddula, Chen, Ih-Sheng
Published in Phytochemistry (Oxford) (01.07.2003)
Published in Phytochemistry (Oxford) (01.07.2003)
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Journal Article
Catabolism of antibody drug conjugates and characterization methods
Shadid, Mohammad, Bowlin, Stephen, Bolleddula, Jayaprakasam
Published in Bioorganic & medicinal chemistry (15.06.2017)
Published in Bioorganic & medicinal chemistry (15.06.2017)
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Journal Article
Prediction of Human Disproportionate and Biliary Excreted Metabolites Using Chimeric Mice with Humanized Liver
Kato, Suguru, Shah, Abhi, Plesescu, Mihaela, Miyata, Yoshinari, Bolleddula, Jayaprakasam, Chowdhury, Swapan, Zhu, Xiaochun
Published in Drug metabolism and disposition (01.10.2020)
Published in Drug metabolism and disposition (01.10.2020)
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Journal Article