HIV-1 Tat and cocaine impact mitochondrial epigenetics: effects on DNA methylation
Doke, Mayur, Jeganathan, Venkatesh, McLaughlin, Jay P., Samikkannu, Thangavel
Published in Epigenetics (02.09.2021)
Published in Epigenetics (02.09.2021)
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Region-specific effects of HIV-1 Tat on intrinsic electrophysiological properties of pyramidal neurons in mouse prefrontal cortex and hippocampus
Cirino, Thomas J, Harden, Scott W, McLaughlin, Jay P, Frazier, Charles J
Published in Journal of neurophysiology (01.04.2020)
Published in Journal of neurophysiology (01.04.2020)
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Identification and Pharmacological Characterization of a Low-Liability Antinociceptive Bifunctional MOR/DOR Cyclic Peptide
Li, Yangmei, Eans, Shainnel O, Ganno-Sherwood, Michelle, Eliasof, Abbe, Houghten, Richard A, McLaughlin, Jay P
Published in Molecules (Basel, Switzerland) (01.11.2023)
Published in Molecules (Basel, Switzerland) (01.11.2023)
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Solid-Phase Synthesis of the Bicyclic Peptide OL-CTOP Containing Two Disulfide Bridges, and an Assessment of Its In Vivo μ-Opioid Receptor Antagonism after Nasal Administration
Rayala, Ramanjaneyulu, Tiller, Annika, Majumder, Shahayra A, Stacy, Heather M, Eans, Shainnel O, Nedovic, Aleksandra, McLaughlin, Jay P, Cudic, Predrag
Published in Molecules (Basel, Switzerland) (01.02.2023)
Published in Molecules (Basel, Switzerland) (01.02.2023)
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Oxidative Metabolism as a Modulator of Kratom’s Biological Actions
Chakraborty, Soumen, Uprety, Rajendra, Slocum, Samuel T, Irie, Takeshi, Le Rouzic, Valerie, Li, Xiaohai, Wilson, Lisa L, Scouller, Brittany, Alder, Amy F, Kruegel, Andrew C, Ansonoff, Michael, Varadi, Andras, Eans, Shainnel O, Hunkele, Amanda, Allaoa, Abdullah, Kalra, Sanjay, Xu, Jin, Pan, Ying Xian, Pintar, John, Kivell, Bronwyn M, Pasternak, Gavril W, Cameron, Michael D, McLaughlin, Jay P, Sames, Dalibor, Majumdar, Susruta
Published in Journal of medicinal chemistry (25.11.2021)
Published in Journal of medicinal chemistry (25.11.2021)
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Journal Article
Characterization of CM-398, a Novel Selective Sigma-2 Receptor Ligand, as a Potential Therapeutic for Neuropathic Pain
Wilson, Lisa L, Alleyne, Amy R, Eans, Shainnel O, Cirino, Thomas J, Stacy, Heather M, Mottinelli, Marco, Intagliata, Sebastiano, McCurdy, Christopher R, McLaughlin, Jay P
Published in Molecules (Basel, Switzerland) (04.06.2022)
Published in Molecules (Basel, Switzerland) (04.06.2022)
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Chronic Voluntary Binge Ethanol Consumption Causes Sex‐Specific Differences in Microglial Signaling Pathways and Withdrawal‐associated Behaviors in Mice
Rath, Meera, Guergues, Jennifer, Pinho, Joao P.C., Zhang, Ping, Nguyen, Truc G., MacFadyen, Kaley A., Peris, Joanna, McLaughlin, Jay P., Stevens, Stanley M., Liu, Bin
Published in Alcoholism, clinical and experimental research (01.09.2020)
Published in Alcoholism, clinical and experimental research (01.09.2020)
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Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site
Uprety, Rajendra, Che, Tao, Zaidi, Saheem A, Grinnell, Steven G, Varga, Balázs R, Faouzi, Abdelfattah, Slocum, Samuel T, Allaoa, Abdullah, Varadi, András, Nelson, Melissa, Bernhard, Sarah M, Kulko, Elizaveta, Le Rouzic, Valerie, Eans, Shainnel O, Simons, Chloe A, Hunkele, Amanda, Subrath, Joan, Pan, Ying Xian, Javitch, Jonathan A, McLaughlin, Jay P, Roth, Bryan L, Pasternak, Gavril W, Katritch, Vsevolod, Majumdar, Susruta
Published in eLife (08.02.2021)
Published in eLife (08.02.2021)
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Bis-Cyclic Guanidine Heterocyclic Peptidomimetics as Opioid Ligands with Mixed μ-, κ- and δ-Opioid Receptor Interactions: A Potential Approach to Novel Analgesics
McLaughlin, Jay P, Rayala, Ramanjaneyulu, Bunnell, Ashley J, Tantak, Mukund P, Eans, Shainnel O, Nefzi, Khadija, Ganno, Michelle L, Dooley, Colette T, Nefzi, Adel
Published in International journal of molecular sciences (25.08.2022)
Published in International journal of molecular sciences (25.08.2022)
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Journal Article
Novel histone modifications in microglia derived from a mouse model of chronic pain
Zhang, Ping, Guergues, Jennifer, Alleyne, Amy R., Cirino, Thomas J., Nadeau, Owen, Figueroa, Ariana M., Stacy, Heather M., Suzuki, Takayoshi, McLaughlin, Jay P., Stevens, Stanley M., Liu, Bin
Published in Proteomics (Weinheim) (01.05.2022)
Published in Proteomics (Weinheim) (01.05.2022)
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Examination of the Novel Sigma-1 Receptor Antagonist, SI 1/28, for Antinociceptive and Anti-allodynic Efficacy against Multiple Types of Nociception with Fewer Liabilities of Use
Wilson, Lisa L, Eans, Shainnel O, Ramadan-Siraj, Insitar, Modica, Maria N, Romeo, Giuseppe, Intagliata, Sebastiano, McLaughlin, Jay P
Published in International journal of molecular sciences (06.01.2022)
Published in International journal of molecular sciences (06.01.2022)
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Journal Article
Characterization of Sigma 1 Receptor Antagonist CM-304 and Its Analog, AZ-66: Novel Therapeutics Against Allodynia and Induced Pain
Cirino, Thomas J, Eans, Shainnel O, Medina, Jessica M, Wilson, Lisa L, Mottinelli, Marco, Intagliata, Sebastiano, McCurdy, Christopher R, McLaughlin, Jay P
Published in Frontiers in pharmacology (14.06.2019)
Published in Frontiers in pharmacology (14.06.2019)
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Phenylalanine Stereoisomers of CJ-15,208 and [d-Trp]CJ-15,208 Exhibit Distinctly Different Opioid Activity Profiles
Brice-Tutt, Ariana C, Senadheera, Sanjeewa N, Ganno, Michelle L, Eans, Shainnel O, Khaliq, Tanvir, Murray, Thomas F, McLaughlin, Jay P, Aldrich, Jane V
Published in Molecules (Basel, Switzerland) (02.09.2020)
Published in Molecules (Basel, Switzerland) (02.09.2020)
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Journal Article
Sleep Disorder and Cocaine Abuse Impact Purine and Pyrimidine Nucleotide Metabolic Signatures
Doke, Mayur, McLaughlin, Jay P, Baniasadi, Hamid, Samikkannu, Thangavel
Published in Metabolites (01.09.2022)
Published in Metabolites (01.09.2022)
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