Microbial enzymes induce colitis by reactivating triclosan in the mouse gastrointestinal tract
Zhang, Jianan, Walker, Morgan E., Sanidad, Katherine Z., Zhang, Hongna, Liang, Yanshan, Zhao, Ermin, Chacon-Vargas, Katherine, Yeliseyev, Vladimir, Parsonnet, Julie, Haggerty, Thomas D., Wang, Guangqiang, Simpson, Joshua B., Jariwala, Parth B., Beaty, Violet V., Yang, Jun, Yang, Haixia, Panigrahy, Anand, Minter, Lisa M., Kim, Daeyoung, Gibbons, John G., Liu, LinShu, Li, Zhengze, Xiao, Hang, Borlandelli, Valentina, Overkleeft, Hermen S., Cloer, Erica W., Major, Michael B., Goldfarb, Dennis, Cai, Zongwei, Redinbo, Matthew R., Zhang, Guodong
Published in Nature communications (10.01.2022)
Published in Nature communications (10.01.2022)
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Journal Article
Quantitative Investigation of Irinotecan Metabolism, Transport, and Gut Microbiome Activation
Parvez, Md Masud, Basit, Abdul, Jariwala, Parth B, Gáborik, Zsuzsanna, Kis, Emese, Heyward, Scott, Redinbo, Matthew R, Prasad, Bhagwat
Published in Drug metabolism and disposition (01.08.2021)
Published in Drug metabolism and disposition (01.08.2021)
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Journal Article
Analysis of RNA–protein networks with RNP-MaP defines functional hubs on RNA
Weidmann, Chase A., Mustoe, Anthony M., Jariwala, Parth B., Calabrese, J. Mauro, Weeks, Kevin M.
Published in Nature biotechnology (01.03.2021)
Published in Nature biotechnology (01.03.2021)
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Journal Article
Relevance of Human Aldoketoreductases and Microbial β -Glucuronidases in Testosterone Disposition
Basit, Abdul, Amory, John K, Mettu, Vijaya Saradhi, Li, Cindy Yanfei, Heyward, Scott, Jariwala, Parth B, Redinbo, Matthew R, Prasad, Bhagwat
Published in Drug metabolism and disposition (01.04.2023)
Published in Drug metabolism and disposition (01.04.2023)
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Journal Article
Discovering the Microbial Enzymes Driving Drug Toxicity with Activity-Based Protein Profiling
Jariwala, Parth B, Pellock, Samuel J, Goldfarb, Dennis, Cloer, Erica W, Artola, Marta, Simpson, Joshua B, Bhatt, Aadra P, Walton, William G, Roberts, Lee R, Major, Michael B, Davies, Gideon J, Overkleeft, Herman S, Redinbo, Matthew R
Published in ACS chemical biology (17.01.2020)
Published in ACS chemical biology (17.01.2020)
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Journal Article
Gut microbial β-glucuronidases influence endobiotic homeostasis and are modulated by diverse therapeutics
Simpson, Joshua B., Walker, Morgan E., Sekela, Joshua J., Ivey, Samantha M., Jariwala, Parth B., Storch, Cameron M., Kowalewski, Mark E., Graboski, Amanda L., Lietzan, Adam D., Walton, William G., Davis, Kacey A., Cloer, Erica W., Borlandelli, Valentina, Hsiao, Yun-Chung, Roberts, Lee R., Perlman, David H., Liang, Xue, Overkleeft, Hermen S., Bhatt, Aadra P., Lu, Kun, Redinbo, Matthew R.
Published in Cell host & microbe (12.06.2024)
Published in Cell host & microbe (12.06.2024)
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Journal Article
Oxygen-Dependent Globin Coupled Sensor Signaling Modulates Motility and Virulence of the Plant Pathogen Pectobacterium carotovorum
Burns, Justin L, Jariwala, Parth B, Rivera, Shannon, Fontaine, Benjamin M, Briggs, Laura, Weinert, Emily E
Published in ACS chemical biology (18.08.2017)
Published in ACS chemical biology (18.08.2017)
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Journal Article
Identification of Ellagic Acid Rhamnoside as a Bioactive Component of a Complex Botanical Extract with Anti-biofilm Activity
Fontaine, Benjamin M, Nelson, Kate, Lyles, James T, Jariwala, Parth B, García-Rodriguez, Jennifer M, Quave, Cassandra L, Weinert, Emily E
Published in Frontiers in microbiology (23.03.2017)
Published in Frontiers in microbiology (23.03.2017)
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Journal Article
Microbial β-glucuronidases drive human periodontal disease etiology
Lietzan, Adam D, Simpson, Joshua B, Walton, William G, Jariwala, Parth B, Xu, Yongmei, Boynton, Marcella H, Liu, Jian, Redinbo, Matthew R
Published in Science advances (05.05.2023)
Published in Science advances (05.05.2023)
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Journal Article
Advanced piperazine-containing inhibitors target microbial β-glucuronidases linked to gut toxicity
Graboski, Amanda L, Simpson, Joshua B, Pellock, Samuel J, Mehta, Naimee, Creekmore, Benjamin C, Ariyarathna, Yamuna, Bhatt, Aadra P, Jariwala, Parth B, Sekela, Josh J, Kowalewski, Mark E, Barker, Natalie K, Mordant, Angie L, Borlandelli, Valentina B, Overkleeft, Hermen, Herring, Laura E, Jin, Jian, I James, Lindsey, Redinbo, Matthew R
Published in RSC chemical biology (28.08.2024)
Published in RSC chemical biology (28.08.2024)
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Journal Article