Impact of a Biomarker-Based Strategy on Oncology Drug Development: A Meta-analysis of Clinical Trials Leading to FDA Approval
Jardim, Denis L, Fontes Jardim, Denis L, Schwaederle, Maria, Wei, Caimiao, Lee, J Jack, Hong, David S, Eggermont, Alexander M, Schilsky, Richard L, Mendelsohn, John, Lazar, Vladimir, Kurzrock, Razelle
Published in JNCI : Journal of the National Cancer Institute (01.11.2015)
Published in JNCI : Journal of the National Cancer Institute (01.11.2015)
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Journal Article
Phosphatidylinositol 3‐kinase pathway genomic alterations in 60,991 diverse solid tumors informs targeted therapy opportunities
Millis, Sherri Z., Jardim, Denis L., Albacker, Lee, Ross, Jeffrey S., Miller, Vincent A., Ali, Siraj M., Kurzrock, Razelle
Published in Cancer (01.04.2019)
Published in Cancer (01.04.2019)
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Journal Article
MET alterations detected in blood-derived circulating tumor DNA correlate with bone metastases and poor prognosis
Ikeda, Sadakatsu, Schwaederle, Maria, Mohindra, Mandakini, Fontes Jardim, Denis L, Kurzrock, Razelle
Published in Journal of hematology and oncology (04.06.2018)
Published in Journal of hematology and oncology (04.06.2018)
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Journal Article
The Clinical and Molecular Profile of Lung Cancer Patients Harboring the TP53 R337H Germline Variant in a Brazilian Cancer Center: The Possible Mechanism of Carcinogenesis
Lopes, Carlos D. H., Antonacio, Fernanda F., Moraes, Priscila M. G., Asprino, Paula F., Galante, Pedro A. F., Jardim, Denis L., de Macedo, Mariana P., Sandoval, Renata L., Katz, Artur, de Castro, Gilberto, Achatz, Maria Isabel
Published in International journal of molecular sciences (10.10.2023)
Published in International journal of molecular sciences (10.10.2023)
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Journal Article
Efficacy and safety of anticancer drug combinations: a meta-analysis of randomized trials with a focus on immunotherapeutics and gene-targeted compounds
Jardim, Denis L., De Melo Gagliato, Débora, Nikanjam, Mina, Barkauskas, Donald A., Kurzrock, Razelle
Published in Oncoimmunology (01.01.2020)
Published in Oncoimmunology (01.01.2020)
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Journal Article
The Challenges of Tumor Mutational Burden as an Immunotherapy Biomarker
Jardim, Denis L., Goodman, Aaron, de Melo Gagliato, Debora, Kurzrock, Razelle
Published in Cancer cell (08.02.2021)
Published in Cancer cell (08.02.2021)
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Journal Article
FBXW7 mutations in patients with advanced cancers: clinical and molecular characteristics and outcomes with mTOR inhibitors
Jardim, Denis L, Wheler, Jennifer J, Hess, Kenneth, Tsimberidou, Apostolia M, Zinner, Ralph, Janku, Filip, Subbiah, Vivek, Naing, Aung, Piha-Paul, Sarina A, Westin, Shannon N, Roy-Chowdhuri, Sinchita, Meric-Bernstam, Funda, Hong, David S
Published in PloS one (19.02.2014)
Published in PloS one (19.02.2014)
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Journal Article
Lessons From the Development of the Immune Checkpoint Inhibitors in Oncology
Jardim, Denis L., de Melo Gagliato, Débora, Kurzrock, Razelle
Published in Integrative cancer therapies (01.12.2018)
Published in Integrative cancer therapies (01.12.2018)
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Journal Article
Analysis of 1,115 patients tested for MET amplification and therapy response in the MD Anderson Phase I Clinic
Jardim, Denis L F, Tang, Chad, Gagliato, Debora De Melo, Falchook, Gerald S, Hess, Kenneth, Janku, Filip, Fu, Siqing, Wheler, Jennifer J, Zinner, Ralph G, Naing, Aung, Tsimberidou, Apostolia M, Holla, Vijaykumar, Li, Marylin M, Roy-Chowdhuri, Sinchita, Luthra, Raja, Salgia, Ravi, Kurzrock, Razelle, Meric-Bernstam, Funda, Hong, David S
Published in Clinical cancer research (15.12.2014)
Published in Clinical cancer research (15.12.2014)
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Journal Article
Haematologic toxicities associated with the addition of bevacizumab in cancer patients
Schutz, Fabio A.B, Jardim, Denis L.F, Je, Youjin, Choueiri, Toni K
Published in European journal of cancer (1990) (01.05.2011)
Published in European journal of cancer (1990) (01.05.2011)
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Journal Article
Choice of 16S Ribosomal RNA Primers Impacts Male Urinary Microbiota Profiling
Heidrich, Vitor, Inoue, Lilian T, Asprino, Paula F, Bettoni, Fabiana, Mariotti, Antonio C H, Bastos, Diogo A, Jardim, Denis L F, Arap, Marco A, Camargo, Anamaria A
Published in Frontiers in cellular and infection microbiology (21.04.2022)
Published in Frontiers in cellular and infection microbiology (21.04.2022)
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Journal Article
Impact of the COVID-19 Pandemic on Oncology Clinical Research in Latin America (LACOG 0420)
Lara Gongora, Aline B, Werutsky, Gustavo, Jardim, Denis L, Nogueira-Rodrigues, Angelica, Barrios, Carlos H, Mathias, Clarissa, Maluf, Fernando, Riechelmann, Rachel, Fraga, Maurício, Gomes, Henry, William, William N, Yamada, Camilla A F, de Castro, Jr, Gilberto, Rosa, Daniela D, de Melo, Andreia C, Sala, Raul, Bustamante, Eva, Bretel, Denisse, Arrieta, Oscar, Cardona, Andrés F, Bastos, Diogo A
Published in JCO global oncology (01.12.2021)
Published in JCO global oncology (01.12.2021)
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Journal Article
Low‐energy amplitude‐modulated electromagnetic field exposure: Feasibility study in patients with hepatocellular carcinoma
Capareli, Fernanda, Costa, Frederico, Tuszynski, Jack A., Sousa, Micelange C., Setogute, Yone de C., Lima, Pablo D., Carvalho, Luciana, Santos, Elizabeth, Gumz, Brenda P., Sabbaga, Jorge, Castria, Tiago B., Jardim, Denis L., Freitas, Daniela, Horvat, Natally, Bezerra, Regis O. F., Testagrossa, Leonardo, Costa, Tiago, Zanesco, Tatiana, Iemma, Antonio F., Abou‐Alfa, Ghassan K.
Published in Cancer medicine (Malden, MA) (01.06.2023)
Published in Cancer medicine (Malden, MA) (01.06.2023)
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Journal Article
Use of Expansion Cohorts in Phase I Trials and Probability of Success in Phase II for 381 Anticancer Drugs
Bugano, Diogo D G, Hess, Kenneth, Jardim, Denis L F, Zer, Alona, Meric-Bernstam, Funda, Siu, Lillian L, Razak, Albiruni R A, Hong, David S
Published in Clinical cancer research (01.08.2017)
Published in Clinical cancer research (01.08.2017)
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Journal Article
Analysis of MET Genetic Aberrations in Patients With Breast Cancer at MD Anderson Phase I Unit
de Melo Gagliato, Debora, Jardim, Denis L. Fontes, Falchook, Gerald, Tang, Chad, Zinner, Ralph, Wheler, Jennifer J, Janku, Filip, Subbiah, Vivek, Piha-Paul, Sarina A, Fu, Siqing, Hess, Kenneth, Roy-Chowdhuri, Sinchita, Moulder, Stacy, Gonzalez-Angulo, Ana M, Meric-Bernstam, Funda, Hong, David S
Published in Clinical breast cancer (01.12.2014)
Published in Clinical breast cancer (01.12.2014)
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Journal Article
Analysis of Drug Development Paradigms for Immune Checkpoint Inhibitors
Jardim, Denis L, de Melo Gagliato, Débora, Giles, Francis J, Kurzrock, Razelle
Published in Clinical cancer research (15.04.2018)
Published in Clinical cancer research (15.04.2018)
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Journal Article
Comprehensive Landscape of Cyclin Pathway Gene Alterations and Co-occurrence with FGF/FGFR Aberrations Across Urinary Tract Tumors
Jardim, Denis L F, Millis, Sherri Z, Ross, Jeffrey S, Lippman, Scott, Ali, Siraj M, Kurzrock, Razelle
Published in The oncologist (Dayton, Ohio) (08.02.2023)
Published in The oncologist (Dayton, Ohio) (08.02.2023)
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Journal Article