MLL oncoprotein levels influence leukemia lineage identities
Janssens, Derek H., Duran, Melodie, Otto, Dominik J., Wu, Weifang, Xu, Yiling, Kirkey, Danielle, Mullighan, Charles G., Yi, Joanna S., Meshinchi, Soheil, Sarthy, Jay F., Ahmad, Kami, Henikoff, Steven
Published in Nature communications (29.10.2024)
Published in Nature communications (29.10.2024)
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Journal Article
Histone deposition pathways determine the chromatin landscapes of H3.1 and H3.3 K27M oncohistones
Sarthy, Jay F, Meers, Michael P, Janssens, Derek H, Henikoff, Jorja G, Feldman, Heather, Paddison, Patrick J, Lockwood, Christina M, Vitanza, Nicholas A, Olson, James M, Ahmad, Kami, Henikoff, Steven
Published in eLife (09.09.2020)
Published in eLife (09.09.2020)
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Journal Article
An Hdac1/Rpd3-Poised Circuit Balances Continual Self-Renewal and Rapid Restriction of Developmental Potential during Asymmetric Stem Cell Division
Janssens, Derek H., Hamm, Danielle C., Anhezini, Lucas, Xiao, Qi, Siller, Karsten H., Siegrist, Sarah E., Harrison, Melissa M., Lee, Cheng-Yu
Published in Developmental cell (27.02.2017)
Published in Developmental cell (27.02.2017)
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Journal Article
Automated in situ chromatin profiling efficiently resolves cell types and gene regulatory programs
Janssens, Derek H, Wu, Steven J, Sarthy, Jay F, Meers, Michael P, Myers, Carrie H, Olson, James M, Ahmad, Kami, Henikoff, Steven
Published in Epigenetics & chromatin (21.12.2018)
Published in Epigenetics & chromatin (21.12.2018)
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Journal Article
Sequential activation of transcriptional repressors promotes progenitor commitment by silencing stem cell identity genes
Rives-Quinto, Noemi, Komori, Hideyuki, Ostgaard, Cyrina M, Janssens, Derek H, Kondo, Shu, Dai, Qi, Moore, Adrian W, Lee, Cheng-Yu
Published in eLife (26.11.2020)
Published in eLife (26.11.2020)
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Journal Article
Global and context-specific transcriptional consequences of oncogenic Fbw7 mutations
Thirimanne, H Nayanga, Wu, Feinan, Janssens, Derek H, Swanger, Jherek, Diab, Ahmed, Feldman, Heather M, Amezquita, Robert A, Gottardo, Raphael, Paddison, Patrick J, Henikoff, Steven, Clurman, Bruce E
Published in eLife (28.02.2022)
Published in eLife (28.02.2022)
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Journal Article
Efficient low-cost chromatin profiling with CUT&Tag
Kaya-Okur, Hatice S., Janssens, Derek H., Henikoff, Jorja G., Ahmad, Kami, Henikoff, Steven
Published in Nature protocols (01.10.2020)
Published in Nature protocols (01.10.2020)
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Journal Article
Trithorax maintains the functional heterogeneity of neural stem cells through the transcription factor buttonhead
Komori, Hideyuki, Xiao, Qi, Janssens, Derek H, Dou, Yali, Lee, Cheng-Yu
Published in eLife (06.10.2014)
Published in eLife (06.10.2014)
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Journal Article
Automated CUT&Tag profiling of chromatin heterogeneity in mixed-lineage leukemia
Janssens, Derek H., Meers, Michael P., Wu, Steven J., Babaeva, Ekaterina, Meshinchi, Soheil, Sarthy, Jay F., Ahmad, Kami, Henikoff, Steven
Published in Nature genetics (01.11.2021)
Published in Nature genetics (01.11.2021)
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Journal Article
Epigenomic analysis of formalin-fixed paraffin-embedded samples by CUT&Tag
Henikoff, Steven, Henikoff, Jorja G., Ahmad, Kami, Paranal, Ronald M., Janssens, Derek H., Russell, Zachary R., Szulzewsky, Frank, Kugel, Sita, Holland, Eric C.
Published in Nature communications (22.09.2023)
Published in Nature communications (22.09.2023)
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Journal Article
Scalable single-cell profiling of chromatin modifications with sciCUT&Tag
Janssens, Derek H., Greene, Jacob E., Wu, Steven J., Codomo, Christine A., Minot, Samuel S., Furlan, Scott N., Ahmad, Kami, Henikoff, Steven
Published in Nature protocols (01.01.2024)
Published in Nature protocols (01.01.2024)
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Journal Article
Selective androgen receptor modulators activate the canonical prostate cancer androgen receptor program and repress cancer growth
Nyquist, Michael D, Ang, Lisa S, Corella, Alexandra, Coleman, Ilsa M, Meers, Michael P, Christiani, Anthony J, Pierce, Cordell, Janssens, Derek H, Meade, Hannah E, Bose, Arnab, Brady, Lauren, Howard, Timothy, De Sarkar, Navonil, Frank, Sander B, Dumpit, Ruth F, Dalton, James T, Corey, Eva, Plymate, Stephen R, Haffner, Michael C, Mostaghel, Elahe A, Nelson, Peter S
Published in The Journal of clinical investigation (15.05.2021)
Published in The Journal of clinical investigation (15.05.2021)
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Journal Article
Nucleosome Patterns in Circulating Tumor DNA Reveal Transcriptional Regulation of Advanced Prostate Cancer Phenotypes
De Sarkar, Navonil, Patton, Robert D, Doebley, Anna-Lisa, Hanratty, Brian, Adil, Mohamed, Kreitzman, Adam J, Sarthy, Jay F, Ko, Minjeong, Brahma, Sandipan, Meers, Michael P, Janssens, Derek H, Ang, Lisa S, Coleman, Ilsa M, Bose, Arnab, Dumpit, Ruth F, Lucas, Jared M, Nunez, Talina A, Nguyen, Holly M, McClure, Heather M, Pritchard, Colin C, Schweizer, Michael T, Morrissey, Colm, Choudhury, Atish D, Baca, Sylvan C, Berchuck, Jacob E, Freedman, Matthew L, Ahmad, Kami, Haffner, Michael C, Montgomery, R Bruce, Corey, Eva, Henikoff, Steven, Nelson, Peter S, Ha, Gavin
Published in Cancer discovery (01.03.2023)
Published in Cancer discovery (01.03.2023)
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Journal Article
Selective androgen receptor modulators activate the canonical prostate cancer androgen receptor program and repress cancer growth
Nyquist, Michael D, Ang, Lisa S, Corella, Alexandra, Coleman, Ilsa M, Meers, Michael P, Christiani, Anthony J, Pierce, Cordell, Janssens, Derek H, Meade, Hannah E, Bose, Arnab, Brady, Lauren, Howard, Timothy, De Sarkar, Navonil, Frank, Sander B, Dumpit, Ruth F, Dalton, James T, Corey, Eva, Plymate, Stephen R, Haffner, Michael C, Mostaghel, Elahe A, Nelson, Peter S
Published in The Journal of clinical investigation (15.06.2021)
Published in The Journal of clinical investigation (15.06.2021)
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Journal Article