A natural substrate-based fluorescence assay for inhibitor screening on diacylglycerol lipase α
van der Wel, Tom, Janssen, Freek J., Baggelaar, Marc P., Deng, Hui, den Dulk, Hans, Overkleeft, Herman S., van der Stelt, Mario
Published in Journal of lipid research (01.04.2015)
Published in Journal of lipid research (01.04.2015)
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Inhibitors of diacylglycerol lipases in neurodegenerative and metabolic disorders
Janssen, Freek J., van der Stelt, Mario
Published in Bioorganic & medicinal chemistry letters (15.08.2016)
Published in Bioorganic & medicinal chemistry letters (15.08.2016)
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Development of an Activity-Based Probe and In Silico Design Reveal Highly Selective Inhibitors for Diacylglycerol Lipase-α in Brain
Baggelaar, Marc P., Janssen, Freek J., van Esbroeck, Annelot C. M., den Dulk, Hans, Allarà, Marco, Hoogendoorn, Sascha, McGuire, Ross, Florea, Bogdan I., Meeuwenoord, Nico, van den Elst, Hans, van der Marel, Gijsbert A., Brouwer, Jaap, Di Marzo, Vincenzo, Overkleeft, Herman S., van der Stelt, Mario
Published in Angewandte Chemie International Edition (11.11.2013)
Published in Angewandte Chemie International Edition (11.11.2013)
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Triazole Ureas Act as Diacylglycerol Lipase Inhibitors and Prevent Fasting-Induced Refeeding
Deng, Hui, Kooijman, Sander, van den Nieuwendijk, Adrianus M. C. H, Ogasawara, Daisuke, van der Wel, Tom, van Dalen, Floris, Baggelaar, Marc P, Janssen, Freek J, van den Berg, Richard J. B. H. N, den Dulk, Hans, Cravatt, Benjamin F, Overkleeft, Herman S, Rensen, Patrick C. N, van der Stelt, Mario
Published in Journal of medicinal chemistry (12.01.2017)
Published in Journal of medicinal chemistry (12.01.2017)
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Journal Article
Discovery of Glycine Sulfonamides as Dual Inhibitors of sn-1-Diacylglycerol Lipase α and α/β-Hydrolase Domain 6
Janssen, Freek J, Deng, Hui, Baggelaar, Marc P, Allarà, Marco, van der Wel, Tom, den Dulk, Hans, Ligresti, Alessia, van Esbroeck, Annelot C. M, McGuire, Ross, Di Marzo, Vincenzo, Overkleeft, Herman S, van der Stelt, Mario
Published in Journal of medicinal chemistry (14.08.2014)
Published in Journal of medicinal chemistry (14.08.2014)
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Comprehensive Analysis of Structure–Activity Relationships of α‑Ketoheterocycles as sn-1-Diacylglycerol Lipase α Inhibitors
Janssen, Freek J, Baggelaar, Marc P, Hummel, Jessica J. A, Overkleeft, Herman S, Cravatt, Benjamin F, Boger, Dale L, van der Stelt, Mario
Published in Journal of medicinal chemistry (24.12.2015)
Published in Journal of medicinal chemistry (24.12.2015)
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Journal Article
Chiral disubstituted piperidinyl ureas: a class of dual diacylglycerol lipase-alpha and ABHD6 inhibitors
Deng, Hui, van der Wel, Tom, van den Berg, Richard J. B. H. N., van den Nieuwendijk, Adrianus M. C. H., Janssen, Freek J., Baggelaar, Marc P., Overkleeft, Hermen S., van der Stelt, Mario
Published in MedChemComm (01.05.2017)
Published in MedChemComm (01.05.2017)
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Inside Back Cover: Development of an Activity-Based Probe and In Silico Design Reveal Highly Selective Inhibitors for Diacylglycerol Lipase-[alpha] in Brain (Angew. Chem. Int. Ed. 46/2013)
Baggelaar, Marc P, Janssen, Freek J, vanEsbroeck, Annelot C M, denDulk, Hans, Allara, Marco, Hoogendoorn, Sascha, McGuire, Ross, Florea, Bogdan I, Meeuwenoord, Nico, vandenElst, Hans, vanderMarel, Gijsbert A, Brouwer, Jaap, DiMarzo, Vincenzo, Overkleeft, Herman S, vanderStelt, Mario
Published in Angewandte Chemie International Edition (11.11.2013)
Published in Angewandte Chemie International Edition (11.11.2013)
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Journal Article
Chiral disubstituted piperidinyl ureas: a class of dual diacylglycerol lipase-α and ABHD6 inhibitorsThe authors declare no competing interests.Electronic supplementary information (ESI) available. See DOI: 10.1039/c7md00029d
Deng, Hui, van der Wel, Tom, van den Berg, Richard J. B. H. N, van den Nieuwendijk, Adrianus M. C. H, Janssen, Freek J, Baggelaar, Marc P, Overkleeft, Hermen S, van der Stelt, Mario
Year of Publication 24.05.2017
Year of Publication 24.05.2017
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Chiral disubstituted piperidinyl ureas: a class of dual diacylglycerol lipase-α and ABHD6 inhibitors† †The authors declare no competing interests. ‡ ‡Electronic supplementary information (ESI) available. See DOI: 10.1039/c7md00029d
Deng, Hui, van der Wel, Tom, van den Berg, Richard J. B. H. N., van den Nieuwendijk, Adrianus M. C. H., Janssen, Freek J., Baggelaar, Marc P., Overkleeft, Hermen S., van der Stelt, Mario
Published in MedChemComm (10.03.2017)
Published in MedChemComm (10.03.2017)
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Journal Article
Inside Back Cover: Development of an Activity-Based Probe and In Silico Design Reveal Highly Selective Inhibitors for Diacylglycerol Lipase-α in Brain (Angew. Chem. Int. Ed. 46/2013)
Baggelaar, Marc P., Janssen, Freek J., van Esbroeck, Annelot C. M., den Dulk, Hans, Allarà, Marco, Hoogendoorn, Sascha, McGuire, Ross, Florea, Bogdan I., Meeuwenoord, Nico, van den Elst, Hans, van der Marel, Gijsbert A., Brouwer, Jaap, Di Marzo, Vincenzo, Overkleeft, Herman S., van der Stelt, Mario
Published in Angewandte Chemie International Edition (11.11.2013)
Published in Angewandte Chemie International Edition (11.11.2013)
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Journal Article
Development of an Activity-Based Probe and In Silico Design Reveal Highly Selective Inhibitors for Diacylglycerol Lipase-[alpha] in Brain
Baggelaar, Marc P, Janssen, Freek J, vanEsbroeck, Annelot C M, denDulk, Hans, Allara, Marco, Hoogendoorn, Sascha, McGuire, Ross, Florea, Bogdan I, Meeuwenoord, Nico, vandenElst, Hans, vanderMarel, Gijsbert A, Brouwer, Jaap, DiMarzo, Vincenzo, Overkleeft, Herman S, vanderStelt, Mario
Published in Angewandte Chemie International Edition (11.11.2013)
Published in Angewandte Chemie International Edition (11.11.2013)
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Journal Article
Development of an Activity-Based Probe and In Silico Design Reveal Highly Selective Inhibitors for Diacylglycerol Lipase-[alpha] in Brain
Baggelaar, Marc P, Janssen, Freek J, vanEsbroeck, Annelot C M, denDulk, Hans, Allara, Marco, Hoogendoorn, Sascha, McGuire, Ross, Florea, Bogdan I, Meeuwenoord, Nico, vandenElst, Hans, vanderMarel, Gijsbert A, Brouwer, Jaap, DiMarzo, Vincenzo, Overkleeft, Herman S, vanderStelt, Mario
Published in Angewandte Chemie (11.11.2013)
Published in Angewandte Chemie (11.11.2013)
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Journal Article
Innenrücktitelbild: Development of an Activity-Based Probe and In Silico Design Reveal Highly Selective Inhibitors for Diacylglycerol Lipase-α in Brain (Angew. Chem. 46/2013)
Baggelaar, Marc P., Janssen, Freek J., van Esbroeck, Annelot C. M., den Dulk, Hans, Allarà, Marco, Hoogendoorn, Sascha, McGuire, Ross, Florea, Bogdan I., Meeuwenoord, Nico, van den Elst, Hans, van der Marel, Gijsbert A., Brouwer, Jaap, Di Marzo, Vincenzo, Overkleeft, Herman S., van der Stelt, Mario
Published in Angewandte Chemie (11.11.2013)
Published in Angewandte Chemie (11.11.2013)
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Journal Article
Development of an Activity-Based Probe and In Silico Design Reveal Highly Selective Inhibitors for Diacylglycerol Lipase-α in Brain
Baggelaar, Marc P., Janssen, Freek J., van Esbroeck, Annelot C. M., den Dulk, Hans, Allarà, Marco, Hoogendoorn, Sascha, McGuire, Ross, Florea, Bogdan I., Meeuwenoord, Nico, van den Elst, Hans, van der Marel, Gijsbert A., Brouwer, Jaap, Di Marzo, Vincenzo, Overkleeft, Herman S., van der Stelt, Mario
Published in Angewandte Chemie (11.11.2013)
Published in Angewandte Chemie (11.11.2013)
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Journal Article
PHARMACEUTICALLY ACTIVE COMPOUNDS AS DAG-LIPASE INHIBITORS
JANSSEN, Freek J, HUMMER, Jessica J.A, VAN DER STELT, Marcelis, BAGGELAR, Marc P, VAN BOECKEL, C.A.A. Stan
Year of Publication 29.03.2017
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Year of Publication 29.03.2017
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