Impairment of DNA Methylation Maintenance Is the Main Cause of Global Demethylation in Naive Embryonic Stem Cells
von Meyenn, Ferdinand, Iurlaro, Mario, Habibi, Ehsan, Liu, Ning Qing, Salehzadeh-Yazdi, Ali, Santos, Fátima, Petrini, Edoardo, Milagre, Inês, Yu, Miao, Xie, Zhenqing, Kroeze, Leonie I., Nesterova, Tatyana B., Jansen, Joop H., Xie, Hehuang, He, Chuan, Reik, Wolf, Stunnenberg, Hendrik G.
Published in Molecular cell (16.06.2016)
Published in Molecular cell (16.06.2016)
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Whole-Genome Bisulfite Sequencing of Two Distinct Interconvertible DNA Methylomes of Mouse Embryonic Stem Cells
Habibi, Ehsan, Brinkman, Arie B., Arand, Julia, Kroeze, Leonie I., Kerstens, Hindrik H.D., Matarese, Filomena, Lepikhov, Konstantin, Gut, Marta, Brun-Heath, Isabelle, Hubner, Nina C., Benedetti, Rosaria, Altucci, Lucia, Jansen, Joop H., Walter, Jörn, Gut, Ivo G., Marks, Hendrik, Stunnenberg, Hendrik G.
Published in Cell stem cell (05.09.2013)
Published in Cell stem cell (05.09.2013)
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Diagnosis and treatment of primary myelodysplastic syndromes in adults: recommendations from the European LeukemiaNet
Malcovati, Luca, Hellström-Lindberg, Eva, Bowen, David, Adès, Lionel, Cermak, Jaroslav, del Cañizo, Consuelo, Della Porta, Matteo G., Fenaux, Pierre, Gattermann, Norbert, Germing, Ulrich, Jansen, Joop H., Mittelman, Moshe, Mufti, Ghulam, Platzbecker, Uwe, Sanz, Guillermo F., Selleslag, Dominik, Skov-Holm, Mette, Stauder, Reinhard, Symeonidis, Argiris, van de Loosdrecht, Arjan A., de Witte, Theo, Cazzola, Mario
Published in Blood (24.10.2013)
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Mutational spectrum and dynamics of clonal hematopoiesis in anemia of older individuals
van Zeventer, Isabelle A., de Graaf, Aniek O., Wouters, Hanneke J.C.M., van der Reijden, Bert A., van der Klauw, Melanie M., de Witte, Theo, Jonker, Marianne A., Malcovati, Luca, Jansen, Joop H., Huls, Gerwin
Published in Blood (02.04.2020)
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Integrative Proteomic Profiling Reveals PRC2-Dependent Epigenetic Crosstalk Maintains Ground-State Pluripotency
van Mierlo, Guido, Dirks, René A.M., De Clerck, Laura, Brinkman, Arie B., Huth, Michelle, Kloet, Susan L., Saksouk, Nehmé, Kroeze, Leonie I., Willems, Sander, Farlik, Matthias, Bock, Christoph, Jansen, Joop H., Deforce, Dieter, Vermeulen, Michiel, Déjardin, Jérôme, Dhaenens, Maarten, Marks, Hendrik
Published in Cell stem cell (03.01.2019)
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In vitro capture and characterization of embryonic rosette-stage pluripotency between naive and primed states
Neagu, Alex, van Genderen, Emiel, Escudero, Irene, Verwegen, Lucas, Kurek, Dorota, Lehmann, Johannes, Stel, Jente, Dirks, René A. M., van Mierlo, Guido, Maas, Alex, Eleveld, Cindy, Ge, Yang, den Dekker, Alexander. T., Brouwer, Rutger W. W., van IJcken, Wilfred F. J., Modic, Miha, Drukker, Micha, Jansen, Joop H., Rivron, Nicolas C., Baart, Esther B., Marks, Hendrik, ten Berge, Derk
Published in Nature cell biology (01.05.2020)
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Clonal evolution in myelodysplastic syndromes
da Silva-Coelho, Pedro, Kroeze, Leonie I., Yoshida, Kenichi, Koorenhof-Scheele, Theresia N., Knops, Ruth, van de Locht, Louis T., de Graaf, Aniek O., Massop, Marion, Sandmann, Sarah, Dugas, Martin, Stevens-Kroef, Marian J., Cermak, Jaroslav, Shiraishi, Yuichi, Chiba, Kenichi, Tanaka, Hiroko, Miyano, Satoru, de Witte, Theo, Blijlevens, Nicole M. A., Muus, Petra, Huls, Gerwin, van der Reijden, Bert A., Ogawa, Seishi, Jansen, Joop H.
Published in Nature communications (21.04.2017)
Published in Nature communications (21.04.2017)
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Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes
Jansen, Joop H, Nikoloski, Gorica, Langemeijer, Saskia M C, Kuiper, Roland P, Knops, Ruth, Massop, Marion, Tönnissen, Evelyn R L T M, van der Heijden, Adrian, Scheele, Theresia N, Vandenberghe, Peter, de Witte, Theo, van der Reijden, Bert A
Published in Nature genetics (01.08.2010)
Published in Nature genetics (01.08.2010)
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Acquired mutations in TET2 are common in myelodysplastic syndromes
Jansen, Joop H, Langemeijer, Saskia M C, Kuiper, Roland P, Berends, Marieke, Knops, Ruth, Aslanyan, Mariam G, Massop, Marion, Stevens-Linders, Ellen, van Hoogen, Patricia, van Kessel, Ad Geurts, Raymakers, Reinier A P, Kamping, Eveline J, Verhoef, Gregor E, Verburgh, Estelle, Hagemeijer, Anne, Vandenberghe, Peter, de Witte, Theo, van der Reijden, Bert A
Published in Nature genetics (01.07.2009)
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Real-Time Quantitative Polymerase Chain Reaction Detection of Minimal Residual Disease by Standardized WT1 Assay to Enhance Risk Stratification in Acute Myeloid Leukemia: A European LeukemiaNet Study
CILLONI, Daniela, RENNEVILLE, Aline, IZZO, Barbara, NOMDEDEU, Josep, VAN DER HEIJDEN, Adrian, VAN DER REIJDEN, BertA, JANSEN, Joop H, VAN DER VELDEN, Vincent H. J, OMMEN, Hans, PREUDHOMME, Claude, SAGLIO, Giuseppe, GRIMWADE, David, HERMITTE, Fabienne, HILLS, Robert K, DALY, Sarah, JOVANOVIC, Jelena V, GOTTARDI, Enrico, FAVA, Milena, SCHNITTGER, Susanne, WEISS, Tamara
Published in Journal of clinical oncology (01.11.2009)
Published in Journal of clinical oncology (01.11.2009)
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Early detection and evolution of preleukemic clones in therapy-related myeloid neoplasms following autologous SCT
Berger, Gerbrig, Kroeze, Leonie I., Koorenhof-Scheele, Theresia N., de Graaf, Aniek O., Yoshida, Kenichi, Ueno, Hiroo, Shiraishi, Yuichi, Miyano, Satoru, van den Berg, Eva, Schepers, Hein, van der Reijden, Bert A., Ogawa, Seishi, Vellenga, Edo, Jansen, Joop H.
Published in Blood (19.04.2018)
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CLPB Mutations Cause 3-Methylglutaconic Aciduria, Progressive Brain Atrophy, Intellectual Disability, Congenital Neutropenia, Cataracts, Movement Disorder
Wortmann, Saskia B., Ziętkiewicz, Szymon, Kousi, Maria, Szklarczyk, Radek, Haack, Tobias B., Gersting, Søren W., Muntau, Ania C., Rakovic, Aleksandar, Renkema, G. Herma, Rodenburg, Richard J., Strom, Tim M., Meitinger, Thomas, Rubio-Gozalbo, M. Estela, Chrusciel, Elzbieta, Distelmaier, Felix, Golzio, Christelle, Jansen, Joop H., van Karnebeek, Clara, Lillquist, Yolanda, Lücke, Thomas, Õunap, Katrin, Zordania, Riina, Yaplito-Lee, Joy, van Bokhoven, Hans, Spelbrink, Johannes N., Vaz, Frédéric M., Pras-Raves, Mia, Ploski, Rafal, Pronicka, Ewa, Klein, Christine, Willemsen, Michel A.A.P., de Brouwer, Arjan P.M., Prokisch, Holger, Katsanis, Nicholas, Wevers, Ron A.
Published in American journal of human genetics (05.02.2015)
Published in American journal of human genetics (05.02.2015)
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TIGIT blockade enhances functionality of peritoneal NK cells with altered expression of DNAM-1/TIGIT/CD96 checkpoint molecules in ovarian cancer
Maas, Ralph Ja, Hoogstad-van Evert, Janneke S, Van der Meer, Jolien Mr, Mekers, Vera, Rezaeifard, Somayeh, Korman, Alan J, de Jonge, Paul Kjd, Cany, Jeannette, Woestenenk, Rob, Schaap, Nicolaas Pm, Massuger, Leon F, Jansen, Joop H, Hobo, Willemijn, Dolstra, Harry
Published in Oncoimmunology (01.01.2020)
Published in Oncoimmunology (01.01.2020)
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Expression levels of genes implicated in the working mechanism of lenalidomide predict treatment response in lower risk myelodysplastic syndrome patients
In 't Hout, Florentien E M, Scheele, Thessa N, Westers, Theresia M, Alhan, Canan, Duetz, Carolien, Cremers, Eline M P, Visser-Wisselaar, Heleen A, Verbrugge, Annelies, Chitu, Dana A, Van der Reijden, Bert A, De Graaf, Aniek O, Van de Loosdrecht, Arjan A, Jansen, Joop H
Published in Haematologica (Roma) (10.10.2024)
Published in Haematologica (Roma) (10.10.2024)
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Characterization of acute myeloid leukemia based on levels of global hydroxymethylation
Kroeze, Leonie I., Aslanyan, Mariam G., van Rooij, Arno, Koorenhof-Scheele, Theresia N., Massop, Marion, Carell, Thomas, Boezeman, Jan B., Marie, Jean-Pierre, Halkes, Constantijn J.M., de Witte, Theo, Huls, Gerwin, Suciu, Stefan, Wevers, Ron A., van der Reijden, Bert A., Jansen, Joop H.
Published in Blood (14.08.2014)
Published in Blood (14.08.2014)
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Impairment of DNA Methylation Maintenance Is the Main Cause of Global Demethylation in Naive Embryonic Stem Cells
von Meyenn, Ferdinand, Iurlaro, Mario, Habibi, Ehsan, Liu, Ning Qing, Salehzadeh-Yazdi, Ali, Santos, Fátima, Petrini, Edoardo, Milagre, Inês, Yu, Miao, Xie, Zhenqing, Kroeze, Leonie I., Nesterova, Tatyana B., Jansen, Joop H., Xie, Hehuang, He, Chuan, Reik, Wolf, Stunnenberg, Hendrik G.
Published in Molecular cell (16.06.2016)
Published in Molecular cell (16.06.2016)
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Implementation of erythroid lineage analysis by flow cytometry in diagnostic models for myelodysplastic syndromes
Cremers, Eline M P, Westers, Theresia M, Alhan, Canan, Cali, Claudia, Visser-Wisselaar, Heleen A, Chitu, Dana A, van der Velden, Vincent H J, Te Marvelde, Jeroen G, Klein, Saskia K, Muus, Petra, Vellenga, Edo, de Greef, Georgina E, Legdeur, Marie-Cecile C J C, Wijermans, Pierre W, Stevens-Kroef, Marian J P L, Silva-Coelho, Pedro da, Jansen, Joop H, Ossenkoppele, Gert J, van de Loosdrecht, Arjan A
Published in Haematologica (Roma) (01.02.2017)
Published in Haematologica (Roma) (01.02.2017)
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Prevalence, predictors, and outcomes of clonal hematopoiesis in individuals aged ≥80 years
van Zeventer, Isabelle A., Salzbrunn, Jonas B., de Graaf, Aniek O., van der Reijden, Bert A., Boezen, H. Marike, Vonk, Judith M., van der Harst, Pim, Schuringa, Jan Jacob, Jansen, Joop H., Huls, Gerwin
Published in Blood advances (27.04.2021)
Published in Blood advances (27.04.2021)
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Transcription factor 4 ( TCF4 ) expression predicts clinical outcome in RUNX1 mutated and translocated acute myeloid leukemia
In't Hout, Florentien E M, Gerritsen, Mylène, Bullinger, Lars, Van der Reijden, Bert A, Huls, Gerwin, Vellenga, Edo, Jansen, Joop H
Published in Haematologica (Roma) (01.09.2020)
Published in Haematologica (Roma) (01.09.2020)
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Allelic Mutations of KITLG, Encoding KIT Ligand, Cause Asymmetric and Unilateral Hearing Loss and Waardenburg Syndrome Type 2
Zazo Seco, Celia, Serrão de Castro, Luciana, van Nierop, Josephine W., Morín, Matías, Jhangiani, Shalini, Verver, Eva J.J., Schraders, Margit, Maiwald, Nadine, Wesdorp, Mieke, Venselaar, Hanka, Spruijt, Liesbeth, Oostrik, Jaap, Schoots, Jeroen, van Reeuwijk, Jeroen, Lelieveld, Stefan H., Huygen, Patrick L.M., Insenser, María, Admiraal, Ronald J.C., Pennings, Ronald J.E., Hoefsloot, Lies H., Arias-Vásquez, Alejandro, de Ligt, Joep, Yntema, Helger G., Jansen, Joop H., Muzny, Donna M., Huls, Gerwin, van Rossum, Michelle M., Lupski, James R., Moreno-Pelayo, Miguel Angel, Kunst, Henricus P.M., Kremer, Hannie
Published in American journal of human genetics (05.11.2015)
Published in American journal of human genetics (05.11.2015)
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