Post-translational modification as a response to cellular stress induced by hemoglobin oxidation in sickle cell disease
Strader, Michael Brad, Jana, Sirsendu, Meng, Fantao, Heaven, Michael R, Shet, Arun S, Thein, Swee Lay, Alayash, Abdu I
Published in Scientific reports (26.08.2020)
Published in Scientific reports (26.08.2020)
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Journal Article
Impact of cold storage on the oxygenation and oxidation reactions of red blood cells
Kassa, Tigist, Jana, Sirsendu, Baek, Jin Hyen, Alayash, Abdu I
Published in Frontiers in physiology (19.08.2024)
Published in Frontiers in physiology (19.08.2024)
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Journal Article
Changes in hemoglobin oxidation and band 3 during blood storage impact oxygen sensing and mitochondrial bioenergetic pathways in the human pulmonary arterial endothelial cell model
Jana, Sirsendu, Kassa, Tigist, Wood, Francine, Hicks, Wayne, Alayash, Abdu I.
Published in Frontiers in physiology (16.10.2023)
Published in Frontiers in physiology (16.10.2023)
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Journal Article
HIF-1α-Dependent Metabolic Reprogramming, Oxidative Stress, and Bioenergetic Dysfunction in SARS-CoV-2-Infected Hamsters
Jana, Sirsendu, Heaven, Michael R, Stauft, Charles B, Wang, Tony T, Williams, Matthew C, D'Agnillo, Felice, Alayash, Abdu I
Published in International journal of molecular sciences (29.12.2022)
Published in International journal of molecular sciences (29.12.2022)
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Journal Article
Differential heme release from various hemoglobin redox states and the upregulation of cellular heme oxygenase‐1
Kassa, Tigist, Jana, Sirsendu, Meng, Fantao, Alayash, Abdu I.
Published in FEBS open bio (01.09.2016)
Published in FEBS open bio (01.09.2016)
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Journal Article
Mitochondrial dysfunction mediated by quinone oxidation products of dopamine: Implications in dopamine cytotoxicity and pathogenesis of Parkinson's disease
Jana, Sirsendu, Sinha, Maitrayee, Chanda, Dalia, Roy, Tapasi, Banerjee, Kalpita, Munshi, Soumyabrata, Patro, Birija S., Chakrabarti, Sasanka
Published in Biochimica et biophysica acta (01.06.2011)
Published in Biochimica et biophysica acta (01.06.2011)
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Journal Article
Comprehensive Biochemical and Biophysical Characterization of Hemoglobin-Based Oxygen Carrier Therapeutics: All HBOCs Are Not Created Equally
Meng, Fantao, Kassa, Tigist, Jana, Sirsendu, Wood, Francine, Zhang, Xiaoyuan, Jia, Yiping, D’Agnillo, Felice, Alayash, Abdu I
Published in Bioconjugate chemistry (16.05.2018)
Published in Bioconjugate chemistry (16.05.2018)
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Journal Article
Antimicrobial 405 nm violet-blue light treatment of ex vivo human platelets leads to mitochondrial metabolic reprogramming and potential alteration of Phospho-proteome
Jana, Sirsendu, Heaven, Michael R., Dahiya, Neetu, Stewart, Caitlin, Anderson, John, MacGregor, Scott, Maclean, Michelle, Alayash, Abdu I., Atreya, Chintamani
Published in Journal of photochemistry and photobiology. B, Biology (01.04.2023)
Published in Journal of photochemistry and photobiology. B, Biology (01.04.2023)
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Journal Article
α-Synuclein induced membrane depolarization and loss of phosphorylation capacity of isolated rat brain mitochondria: Implications in Parkinson’s disease
Banerjee, Kalpita, Sinha, Maitrayee, Pham, Chi Le Lan, Jana, Sirsendu, Chanda, Dalia, Cappai, Roberto, Chakrabarti, Sasanka
Published in FEBS letters (16.04.2010)
Published in FEBS letters (16.04.2010)
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Journal Article
Mechanism-Based Targeting of Sickle Cell Pathobiology and Pain with Novel Transdermal Curcumin
Goel, Yugal, Arellano, Mya Angela, Fouda, Raghda T, Kerr, Daniel, Jana, Sirsendu, Lomeli, Reina Alexis, Velasco, Graham J, Banerjee, Probal, Argueta, Donovan Alexander, Gupta, Mihir, Prince, Richard, Alayash, Abdu, Friedman, Joel, Gupta, Kalpna
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Journal Article
Sickle Cell Hemoglobin in the Ferryl State Promotes βCys-93 Oxidation and Mitochondrial Dysfunction in Epithelial Lung Cells (E10)
Kassa, Tigist, Jana, Sirsendu, Strader, Michael Brad, Meng, Fantao, Jia, Yiping, Wilson, Michael T., Alayash, Abdu I.
Published in The Journal of biological chemistry (13.11.2015)
Published in The Journal of biological chemistry (13.11.2015)
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Journal Article
Hydroxyurea Reverses Dysfunctional Ubiquitin-Proteasomal System in Sickle CELL Disease and Suppresses Posttranslational Alterations in Hemoglobin and CELL Membranes
Thein, Swee Lay, Shet, Arun S, Strader, Michael Brad, Meng, Fanato, Heaven, Michael, Sirsendu, Jana, Alayash, Abdu
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Journal Article
Mitapivat increases ATP and decreases oxidative stress and erythrocyte mitochondria retention in a SCD mouse model
Quezado, Zenaide M.N., Kamimura, Sayuri, Smith, Meghann, Wang, Xunde, Heaven, Michael R., Jana, Sirsendu, Vogel, Sebastian, Zerfas, Patricia, Combs, Christian A., Almeida, Luis E.F., Li, Quan, Quezado, Martha, Horkayne-Szakaly, Iren, Kosinski, Penelope A., Yu, Shaoxia, Kapadnis, Unnati, Kung, Charles, Dang, Lenny, Wakim, Paul, Eaton, William A., Alayash, Abdu I., Thein, Swee Lay
Published in Blood cells, molecules, & diseases (01.07.2022)
Published in Blood cells, molecules, & diseases (01.07.2022)
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Journal Article
Redox states of hemoglobin determine left ventricle pressure recovery and activity of mitochondrial complex IV in hypoxic rat hearts
Edmondson, Makhosazane, Jana, Sirsendu, Meng, Fantao, Strader, Michael Brad, Baek, Jin Hyen, Gao, Yamei, Buehler, Paul W., Alayash, Abdu I.
Published in Free radical biology & medicine (01.09.2019)
Published in Free radical biology & medicine (01.09.2019)
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Journal Article
Depolarization and cardiolipin depletion in aged rat brain mitochondria: Relationship with oxidative stress and electron transport chain activity
Sen, Tanusree, Sen, Nilkantha, Jana, Sirsendu, Khan, Firoj Hossain, Chatterjee, Uttara, Chakrabarti, Sasanka
Published in Neurochemistry international (01.04.2007)
Published in Neurochemistry international (01.04.2007)
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Journal Article
Hemoglobin oxidation-dependent reactions promote interactions with band 3 and oxidative changes in sickle cell-derived microparticles
Jana, Sirsendu, Strader, Michael Brad, Meng, Fantao, Hicks, Wayne, Kassa, Tigist, Tarandovskiy, Ivan, De Paoli, Silvia, Simak, Jan, Heaven, Michael R, Belcher, John D, Vercellotti, Gregory M, Alayash, Abdu I
Published in JCI insight (02.11.2018)
Published in JCI insight (02.11.2018)
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