Small cyclic sodium channel inhibitors
Peigneur, Steve, da Costa Oliveira, Cristina, de Sousa Fonseca, Flávia Cristina, McMahon, Kirsten L., Mueller, Alexander, Cheneval, Olivier, Cristina Nogueira Freitas, Ana, Starobova, Hana, Dimitri Gama Duarte, Igor, Craik, David J., Vetter, Irina, de Lima, Maria Elena, Schroeder, Christina I., Tytgat, Jan
Published in Biochemical pharmacology (01.01.2021)
Published in Biochemical pharmacology (01.01.2021)
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Journal Article
Active Sites of Spinoxin, a Potassium Channel Scorpion Toxin, Elucidated by Systematic Alanine Scanning
Peigneur, Steve, Yamaguchi, Yoko, Kawano, Chihiro, Nose, Takeru, Nirthanan, Selvanayagam, Gopalakrishnakone, Ponnampalam, Tytgat, Jan, Sato, Kazuki
Published in Biochemistry (Easton) (31.05.2016)
Published in Biochemistry (Easton) (31.05.2016)
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Journal Article
Green mamba peptide targets type-2 vasopressin receptor against polycystic kidney disease
Ciolek, Justyna, Reinfrank, Helen, Quinton, Loïc, Viengchareun, Say, Stura, Enrico A., Vera, Laura, Sigismeau, Sabrina, Mouillac, Bernard, Orcel, Hélène, Peigneur, Steve, Tytgat, Jan, Droctové, Laura, Beau, Fabrice, Nevoux, Jerome, Lombès, Marc, Mourier, Gilles, De Pauw, Edwin, Servent, Denis, Mendre, Christiane, Witzgall, Ralph, Gilles, Nicolas
Published in Proceedings of the National Academy of Sciences - PNAS (03.07.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (03.07.2017)
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Journal Article
Web Resource
Electrophysiological characterization of Tityus obscurus β toxin 1 (To1) on Na+-channel isoforms
Tibery, Diogo Vieira, Campos, Leandro Ambrósio, Mourão, Caroline Barbosa Farias, Peigneur, Steve, e Carvalho, Andréa Cruz, Tytgat, Jan, Schwartz, Elisabeth Ferroni
Published in Biochimica et biophysica acta. Biomembranes (01.01.2019)
Published in Biochimica et biophysica acta. Biomembranes (01.01.2019)
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Journal Article
Solution structure and functional analysis of HelaTx1: the first toxin member of the κ-KTx5 subfamily
Park, Bong Gyu, Peigneur, Steve, Esaki, Nao, Yamaguchi, Yoko, Ryu, Jae Ha, Tytgat, Jan, Kim, Jae Il, Sato, Kazuki
Published in BMB reports (31.05.2020)
Published in BMB reports (31.05.2020)
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Journal Article
Towards toxin PEGylation: The example of rCollinein-1, a snake venom thrombin-like enzyme, as a PEGylated biopharmaceutical prototype
Pinheiro-Junior, Ernesto Lopes, Boldrini-França, Johara, Takeda, Agnes Alessandra Sekijima, Costa, Tássia Rafaella, Peigneur, Steve, Cardoso, Iara Aimê, Oliveira, Isadora Sousa de, Sampaio, Suely Vilela, de Mattos Fontes, Marcos Roberto, Tytgat, Jan, Arantes, Eliane Candiani
Published in International journal of biological macromolecules (01.11.2021)
Published in International journal of biological macromolecules (01.11.2021)
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Journal Article
Antinociceptive effect induced by a PnPP-19 derivative: new insights into venom peptides targeting opioid receptors
Nogueira Freitas, Ana Cristina, Peigneur, Steve, Marcondes Machado, Marcelo Ferreira, Carmona, Adriana Karaoglanovic, Tytgat, Jan, Elena de Lima, Maria
Published in Toxicon (Oxford) (05.03.2019)
Published in Toxicon (Oxford) (05.03.2019)
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Journal Article
Newly Discovered Peptides from the Coral Heliofungia actiniformis Show Structural and Functional Diversity
Schmidt, Casey A., Cooke, Ira, Wilson, David T., Miller, David J., Peigneur, Steve, Tytgat, Jan, Field, Matthew, Takjoo, Rozita, Smout, Michael J., Loukas, Alex, Daly, Norelle L.
Published in Journal of natural products (Washington, D.C.) (22.07.2022)
Published in Journal of natural products (Washington, D.C.) (22.07.2022)
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Journal Article
In-depth characterization of HelaTx1, A scorpion toxin targeting Kv channels
Peigneur, Steve, Parka, Bong Gyu, Yamaguchi, Yoko, Esaki, Nao, Ryu, Jae Ha, Kim, Jae Il, Sato, Kazuki, Tytgat, Jan
Published in Toxicon (Oxford) (01.02.2019)
Published in Toxicon (Oxford) (01.02.2019)
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Journal Article
α-nemertides, a novel family of marine peptide neurotoxins from ribbon worms
Andersson, Håkan S., Jacobsson, Erik, Strand, Malin, Peigneur, Steve, Lebbe, Eline K.M., Rosengren, K. Johan, Göransson, Ulf, Tytgat, Jan
Published in Toxicon (01.02.2019)
Published in Toxicon (01.02.2019)
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Journal Article
Conference Proceeding
Expression of an α-KTx from Tityus serrulatus scorpion venom in Pichia pastoris yeast and its preliminary electrophysiological characterization
Cordeiro, Francielle Almeida, Amorim, Fernanda Gobbi, Boldrini-França, Johara, Pinheiro-Junior, Ernesto Lopes, Cardoso, Iara Aimê, Peigneur, Steve, Tytgat, Jan, Arantes, Eliane Candiani
Published in Toxicon (Oxford) (20.04.2020)
Published in Toxicon (Oxford) (20.04.2020)
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Journal Article
The insecticidal wasp toxin Γ–Pompilidotoxin is a linear peptide modulating voltage-gated sodium channels
Peigneur, Steve, Tsarev, Andrey V., Paramonov, Alexander S., Schroeder, Christina I., Ikonomopoulou, Maria P., Inagaki, Hidetoshi, Craik, David J., Konno, Katsuhiro, Shenkarev, Zakhar O., Tytgat, Jan
Published in Toxicon (Oxford) (20.04.2020)
Published in Toxicon (Oxford) (20.04.2020)
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Journal Article
Phaiodotoxin, a novel structural class of insect‐toxin isolated from the venom of the Mexican scorpion Anuroctonus phaiodactylus
Valdez‐Cruz, Norma A., Batista, Cesar V. F., Zamudio, Fernando Z., Bosmans, Frank, Tytgat, Jan, Possani, Lourival D.
Published in European journal of biochemistry (01.12.2004)
Published in European journal of biochemistry (01.12.2004)
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Journal Article
Heterologous expression of Ts8, a neurotoxin from Tityus serrulatus venom, evidences its antifungal activity
Cordeiro, Francielle Almeida, Amorim, Fernanda Gobbi, Boldrini-França, Johara, Pinheiro-Júnior, Ernesto Lopes, Cardoso, Iara Aimê, Zoccal, Karina Furlani, Peigneur, Steve, Faccioli, Lucia Helena, Tytgat, Jan, Arantes, Eliane Candiani
Published in Toxicon (Oxford) (30.10.2022)
Published in Toxicon (Oxford) (30.10.2022)
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Journal Article
Web Resource
First report on BaltCRP, a cysteine-rich secretory protein (CRISP) from Bothrops alternatus venom: Effects on potassium channels and inflammatory processes
Bernardes, Carolina Petri, Menaldo, Danilo Luccas, Zoccal, Karina Furlani, Boldrini-França, Johara, Peigneur, Steve, Arantes, Eliane Candiane, Rosa, José Cesar, Faccioli, Lúcia Helena, Tytgat, Jan, Sampaio, Suely Vilela
Published in International journal of biological macromolecules (01.11.2019)
Published in International journal of biological macromolecules (01.11.2019)
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Journal Article
Synthetic polypeptide crotamine: characterization as a myotoxin and as a target of combinatorial peptides
Pompeia, Celine, Frare, Eduardo Osório, Peigneur, Steve, Tytgat, Jan, da Silva, Álvaro Prieto, de Oliveira, Eduardo Brandt, Pereira, Alexandre, Kerkis, Irina, Kolonin, Mikhail G.
Published in Journal of molecular medicine (Berlin, Germany) (2022)
Published in Journal of molecular medicine (Berlin, Germany) (2022)
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Journal Article
A Centipede Toxin Family Defines an Ancient Class of CSαβ Defensins
Dash, Thomas S., Shafee, Thomas, Harvey, Peta J., Zhang, Chuchu, Peigneur, Steve, Deuis, Jennifer R., Vetter, Irina, Tytgat, Jan, Anderson, Marilyn A., Craik, David J., Durek, Thomas, Undheim, Eivind A.B.
Published in Structure (London) (05.02.2019)
Published in Structure (London) (05.02.2019)
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Journal Article
Discovery of K V 1.3 ion channel inhibitors: Medicinal chemistry approaches and challenges
Gubič, Špela, Hendrickx, Louise A, Toplak, Žan, Sterle, Maša, Peigneur, Steve, Tomašič, Tihomir, Pardo, Luis A, Tytgat, Jan, Zega, Anamarija, Mašič, Lucija P
Published in Medicinal research reviews (01.07.2021)
Published in Medicinal research reviews (01.07.2021)
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Journal Article
Trancriptomic approach reveals the molecular diversity of Hottentotta conspersus (Buthidae) venom
Mille, Bea G., Peigneur, Steve, Predel, Reinhard, Tytgat, Jan
Published in Toxicon (Oxford) (01.06.2015)
Published in Toxicon (Oxford) (01.06.2015)
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Journal Article