We're Not "DON" Yet: Optimal Dosing and Prodrug Delivery of 6-Diazo-5-oxo-L-norleucine
Lemberg, Kathryn M, Vornov, James J, Rais, Rana, Slusher, Barbara S
Published in Molecular cancer therapeutics (01.09.2018)
Published in Molecular cancer therapeutics (01.09.2018)
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Journal Article
The orally active glutamate carboxypeptidase II inhibitor E2072 exhibits sustained nerve exposure and attenuates peripheral neuropathy
Wozniak, Krystyna M, Wu, Ying, Vornov, James J, Lapidus, Rena, Rais, Rana, Rojas, Camilo, Tsukamoto, Takashi, Slusher, Barbara S
Published in The Journal of pharmacology and experimental therapeutics (01.12.2012)
Published in The Journal of pharmacology and experimental therapeutics (01.12.2012)
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Journal Article
Selective inhibition of NAALADase, which converts NAAG to glutamate, reduces ischemic brain injury
Slusher, Barbara S, Vornov, James J, Thomas, Ajit G, Hurn, Patricia D, Harukuni, Izumi, Bhardwaj, Anish, Traystman, Richard J, Robinson, Michael B, Britton, Paul, Lu, X.-C. May, Tortella, Frank C, Wozniak, Krystyna M, Yudkoff, Marc, Potter, Beth M, Jackson, Paul F
Published in Nature medicine (01.12.1999)
Published in Nature medicine (01.12.1999)
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Preclinical pharmacology and pharmacokinetics of CERC‐301, a GluN2B‐selective N‐methyl‐D‐aspartate receptor antagonist
Garner, Rachel, Gopalakrishnan, Shobha, McCauley, John A., Bednar, Rodney A., Gaul, Stanley L., Mosser, Scott D., Kiss, Laszlo, Lynch, Joseph J., Patel, Shil, Fandozzi, Christine, Lagrutta, Armando, Briscoe, Richard, Liverton, Nigel J., Paterson, Blake M., Vornov, James J., Mazhari, Reza
Published in Pharmacology research & perspectives (01.12.2015)
Published in Pharmacology research & perspectives (01.12.2015)
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Journal Article
Looking for Drugs in All the Wrong Places: Use of GCPII Inhibitors Outside the Brain
Vornov, James J., Peters, Diane, Nedelcovych, Mike, Hollinger, Kristen, Rais, Rana, Slusher, Barbara S.
Published in Neurochemical research (01.06.2020)
Published in Neurochemical research (01.06.2020)
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Journal Article
Peripheral Neuropathy Induced by Microtubule-Targeted Chemotherapies: Insights into Acute Injury and Long-term Recovery
Wozniak, Krystyna M, Vornov, James J, Wu, Ying, Liu, Ying, Carozzi, Valentina A, Rodriguez-Menendez, Virginia, Ballarini, Elisa, Alberti, Paola, Pozzi, Eleonora, Semperboni, Sara, Cook, Brett M, Littlefield, Bruce A, Nomoto, Kenichi, Condon, Krista, Eckley, Sean, DesJardins, Christopher, Wilson, Leslie, Jordan, Mary A, Feinstein, Stuart C, Cavaletti, Guido, Polydefkis, Michael, Slusher, Barbara S
Published in Cancer research (Chicago, Ill.) (01.02.2018)
Published in Cancer research (Chicago, Ill.) (01.02.2018)
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Sustained Accumulation of Microtubule-Binding Chemotherapy Drugs in the Peripheral Nervous System: Correlations with Time Course and Neurotoxic Severity
Wozniak, Krystyna M, Vornov, James J, Wu, Ying, Nomoto, Kenichi, Littlefield, Bruce A, DesJardins, Christopher, Yu, Yanke, Lai, George, Reyderman, Larisa, Wong, Nancy, Slusher, Barbara S
Published in Cancer research (Chicago, Ill.) (01.06.2016)
Published in Cancer research (Chicago, Ill.) (01.06.2016)
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FOLH1 /GCPII is elevated in IBD patients, and its inhibition ameliorates murine IBD abnormalities
Rais, Rana, Jiang, Weiwei, Zhai, Huihong, Wozniak, Krystyna M, Stathis, Marigo, Hollinger, Kristen R, Thomas, Ajit G, Rojas, Camilo, Vornov, James J, Marohn, Michael, Li, Xuhang, Slusher, Barbara S
Published in JCI insight (04.08.2016)
Published in JCI insight (04.08.2016)
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Journal Article
Ghrelin agonist HM01 attenuates chemotherapy-induced neurotoxicity in rodent models
Chiorazzi, Alessia, Wozniak, Krystyna M., Rais, Rana, Wu, Ying, Gadiano, Alexandra J., Farah, Mohamed H., Liu, Ying, Canta, Annalisa, Alberti, Paola, Rodriguez-Menendez, Virginia, Meregalli, Cristina, Fumagalli, Giulia, Monza, Laura, Pozzi, Eleonora, Vornov, James J., Polydefkis, Michael, Pietra, Claudio, Slusher, Barbara S., Cavaletti, Guido
Published in European journal of pharmacology (05.12.2018)
Published in European journal of pharmacology (05.12.2018)
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Pharmacokinetics and pharmacodynamics of the glutamate carboxypeptidase II inhibitor 2-MPPA show prolonged alleviation of neuropathic pain through an indirect mechanism
Vornov, James J, Wozniak, Krystyna M, Wu, Ying, Rojas, Camilo, Rais, Rana, Slusher, Barbara S
Published in The Journal of pharmacology and experimental therapeutics (01.09.2013)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2013)
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Journal Article
Gastrointestinal delivery of propofol from fospropofol: its bioavailability and activity in rodents and human volunteers
Wozniak, Krystyna M, Vornov, James J, Mistry, Bipin M, Wu, Ying, Rais, Rana, Slusher, Barbara S
Published in Journal of translational medicine (29.05.2015)
Published in Journal of translational medicine (29.05.2015)
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Journal Article
Sedation with GPI 15715, a water-soluble prodrug of propofol, using target-controlled infusion in volunteers
FECHNER, Jörg, IHMSEN, Harald, SCHIESSL, Christine, JELEAZCOV, Christian, VORNOV, James J, SCHWILDEN, Helmut, SCHÜTTLER, Jurgen
Published in Anesthesia and analgesia (01.03.2005)
Published in Anesthesia and analgesia (01.03.2005)
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Journal Article
Toxicity induced by a polyglutamated folate analog is attenuated by NAALADase inhibition
Thomas, Ajit G, Olkowski, Jennifer L, Vornov, James J, Slusher, Barbara S
Published in Brain research (02.10.1999)
Published in Brain research (02.10.1999)
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Journal Article
Cerebellar top-of-the-basilar syndrome
Silverman, Isaac E, Geschwind, Michael D, Vornov, James J
Published in Clinical neurology and neurosurgery (01.12.1998)
Published in Clinical neurology and neurosurgery (01.12.1998)
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Conference Proceeding
Comparative pharmacokinetics and pharmacodynamics of the new propofol prodrug GPI 15715 and propofol emulsion
FECHNER, Jörg, IHMSEN, Harald, HATTERSCHEID, Dirk, JELEAZCOV, Christian, SCHIESSL, Christine, VORNOV, James J, SCHWILDEN, Helmut, SCHÜTTLER, Jürgen
Published in Anesthesiology (Philadelphia) (01.09.2004)
Published in Anesthesiology (Philadelphia) (01.09.2004)
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