Understanding Mechanisms of Food Effect and Developing Reliable PBPK Models Using a Middle-out Approach
Pepin, Xavier J. H., Huckle, James E., Alluri, Ravindra V., Basu, Sumit, Dodd, Stephanie, Parrott, Neil, Emami Riedmaier, Arian
Published in The AAPS journal (04.01.2021)
Published in The AAPS journal (04.01.2021)
Get full text
Journal Article
CMC development of [14C]-labeled sotorasib for the conduct of microtracer human ADME study
Sharma, Sonika, Agarwal, Prashant, Parsons, Andrew T., Huckle, James E., Correll, Tiffany L.
Published in AAPS open (01.12.2023)
Published in AAPS open (01.12.2023)
Get full text
Journal Article
Gadolinium Deposition in Humans: When Did We Learn That Gadolinium Was Deposited In Vivo?
Huckle, James E, Altun, Ersan, Jay, Michael, Semelka, Richard C
Published in Investigative radiology (01.04.2016)
Published in Investigative radiology (01.04.2016)
Get more information
Journal Article
Neutron-activatable holmium-containing mesoporous silica nanoparticles as a potential radionuclide therapeutic agent for ovarian cancer
Di Pasqua, Anthony J, Yuan, Hong, Chung, Younjee, Kim, Jin-Ki, Huckle, James E, Li, Chenxi, Sadgrove, Matthew, Tran, Thanh Huyen, Jay, Michael, Lu, Xiuling
Published in Journal of Nuclear Medicine (01.01.2013)
Published in Journal of Nuclear Medicine (01.01.2013)
Get full text
Journal Article
Orally administered DTPA penta-ethyl ester for the decorporation of inhaled (241)Am
Sueda, Katsuhiko, Sadgrove, Matthew P, Huckle, James E, Leed, Marina G D, Weber, Waylon M, Doyle-Eisele, Melanie, Guilmette, Raymond A, Jay, Michael
Published in Journal of pharmaceutical sciences (01.05.2014)
Published in Journal of pharmaceutical sciences (01.05.2014)
Get full text
Journal Article
Species-dependent chelation of (241)Am by DTPA Di-ethyl ester
Huckle, James E, Sadgrove, Matthew P, Mumper, Russell J, Jay, Michael
Published in Health physics (1958) (01.04.2015)
Published in Health physics (1958) (01.04.2015)
Get more information
Journal Article
Orally Administered DTPA Penta-Ethyl Ester for the Decorporation of Inhaled 241Am
Sueda, Katsuhiko, Sadgrove, Matthew P., Huckle, James E., Leed, Marina G.D., Weber, Waylon M., Doyle-Eisele, Melanie, Guilmette, Raymond A., Jay, Michael
Published in Journal of pharmaceutical sciences (01.05.2014)
Published in Journal of pharmaceutical sciences (01.05.2014)
Get full text
Journal Article
Orally administered DTPA di-ethyl ester for decorporation of (241)Am in dogs: Assessment of safety and efficacy in an inhalation-contamination model
Huckle, James E, Sadgrove, Matthew P, Pacyniak, Erik, Leed, Marina G D, Weber, Waylon M, Doyle-Eisele, Melanie, Guilmette, Raymond A, Agha, Bushra J, Susick, Robert L, Mumper, Russell J, Jay, Michael
Published in International journal of radiation biology (01.07.2015)
Published in International journal of radiation biology (01.07.2015)
Get full text
Journal Article
Synthesis and Physicochemical Characterization of a Diethyl Ester Prodrug of DTPA and Its Investigation as an Oral Decorporation Agent in Rats
Huckle, James E., Sadgrove, Matthew P., Leed, Marina G. D., Yang, Yu-Tsai, Mumper, Russell J., Semelka, Richard C., Jay, Michael
Published in The AAPS journal (01.07.2016)
Published in The AAPS journal (01.07.2016)
Get full text
Journal Article
Preparation of Neutron-Activatable Holmium Nanoparticles for the Treatment of Ovarian Cancer Metastases
Di Pasqua, Anthony J., Huckle, James E., Kim, Jin-Ki, Chung, Younjee, Wang, Andrew Z., Jay, Michael, Lu, Xiuling
Published in Small (Weinheim an der Bergstrasse, Germany) (10.04.2012)
Published in Small (Weinheim an der Bergstrasse, Germany) (10.04.2012)
Get full text
Journal Article
MCL-1 INHIBITOR FORMULATIONS
SEAN BROWN, DARREN L REID, JAMES E HUCKLE, MARKIAN STEC, WU TIAN, FERNANDO ANTONIO AVAREZ-NUNEZ
Year of Publication 10.03.2022
Get full text
Year of Publication 10.03.2022
Patent
METHYLATION OF Mcl-1 COMPOUND
SEAN BROWN, HWANG TSANG-LIN, JANINE K TOM, JAMES E HUCKLE, MICHAEL ACHMATOWICZ, NEIL FRED LANGILLE, MARKIAN STEC, CUI SHENG, WU TIAN
Year of Publication 11.10.2021
Get full text
Year of Publication 11.10.2021
Patent
Orally administered DTPA di-ethyl ester for decorporation of 241 Am in dogs: Assessment of safety and efficacy in an inhalation-contamination model
Huckle, James E., Sadgrove, Matthew P., Pacyniak, Erik, Leed, Marina G. D., Weber, Waylon M., Doyle-Eisele, Melanie, Guilmette, Raymond A., Agha, Bushra J., Susick, Robert L., Mumper, Russell J., Jay, Michael
Published in International journal of radiation biology (03.07.2015)
Published in International journal of radiation biology (03.07.2015)
Get full text
Journal Article
Orally administered DTPA di-ethyl ester for decorporation of 241Am in dogs: Assessment of safety and efficacy in an inhalation-contamination model
Huckle, James E., Sadgrove, Matthew P., Pacyniak, Erik, Leed, Marina G. D., Weber, Waylon M., Doyle-Eisele, Melanie, Guilmette, Raymond A., Agha, Bushra J., Susick, Robert L., Mumper, Russell J., Jay, Michael
Published in International journal of radiation biology (03.07.2015)
Published in International journal of radiation biology (03.07.2015)
Get full text
Journal Article
MCL-1 INHIBITOR FORMULATIONS
HUCKLE, JAMES E, STEC, MARKIAN M, REID, DARREN L, WU, TIAN, ALVAREZ-NUNEZ, FERNANDO A, BROWN, SEAN P
Year of Publication 05.10.2023
Get full text
Year of Publication 05.10.2023
Patent
MCL-1 INHIBITOR FORMULATIONS
REID, Darren L, STEC, Markian, AVAREZ-NUNEZ, Fernando Antonio, BROWN, Sean P, HUCKLE, James E, WU, Tian
Year of Publication 05.07.2023
Get full text
Year of Publication 05.07.2023
Patent
Preparation of Mcl-1 inhibiting compound by methylation in the presence of water
TOM, Janine K, LANGILLE, Neil Fred, CUI, Sheng, HWANG, Tsang-Lin, STEC, Markian, ACHMATOWICZ, Michal, BROWN, Sean P, HUCKLE, James E, WU, Tian
Year of Publication 22.02.2024
Get full text
Year of Publication 22.02.2024
Patent
Mcl-1 inhibitor formulations
REID, Darren L, STEC, Markian, AVAREZ-NUNEZ, Fernando Antonio, BROWN, Sean P, HUCKLE, James E, WU, Tian
Year of Publication 30.03.2023
Get full text
Year of Publication 30.03.2023
Patent
Preparation of Mcl-1 inhibiting compound by methylation in the presence of water
TOM, Janine K, LANGILLE, Neil Fred, CUI, Sheng, HWANG, Tsang-Lin, STEC, Markian, ACHMATOWICZ, Michal, BROWN, Sean P, HUCKLE, James E, WU, Tian
Year of Publication 16.11.2023
Get full text
Year of Publication 16.11.2023
Patent
CRYSTALLINE FORMS OF AN MCL-1 INHIBITOR
PARENT Stephan, XIAO Lingyun, ACHMATOWICZ Michal, KELLY Ron C, REID Darren L, TENG Jing, LUU Van, CHAVES Mary, FARRELL Robert P, STEC Markian, HUCKLE James E, WU Tian
Year of Publication 15.08.2024
Get full text
Year of Publication 15.08.2024
Patent