Anesthesia Leads to Tau Hyperphosphorylation through Inhibition of Phosphatase Activity by Hypothermia
Planel, Emmanuel, Richter, Karl E. G, Nolan, Charles E, Finley, James E, Liu, Li, Wen, Yi, Krishnamurthy, Pavan, Herman, Mathieu, Wang, Lili, Schachter, Joel B, Nelson, Robert B, Lau, Lit-Fui, Duff, Karen E
Published in The Journal of neuroscience (21.03.2007)
Published in The Journal of neuroscience (21.03.2007)
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Microphysiological systems in early stage drug development: Perspectives on current applications and future impact
Kopec, Anna K., Yokokawa, Ryuji, Khan, Nasir, Horii, Ikuo, Finley, James E., Bono, Christine P., Donovan, Carol, Roy, Jessica, Harney, Julie, Burdick, Andrew D., Jessen, Bart, Lu, Shuyan, Collinge, Mark, Sadeghian, Ramin Banan, Derzi, Mazin, Tomlinson, Lindsay, Burkhardt, John E.
Published in Journal of toxicological sciences (01.01.2021)
Published in Journal of toxicological sciences (01.01.2021)
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Receptor-Mediated Delivery of CRISPR-Cas9 Endonuclease for Cell-Type-Specific Gene Editing
Rouet, Romain, Thuma, Benjamin A, Roy, Marc D, Lintner, Nathanael G, Rubitski, David M, Finley, James E, Wisniewska, Hanna M, Mendonsa, Rima, Hirsh, Ariana, de Oñate, Lorena, Compte Barrón, Joan, McLellan, Thomas J, Bellenger, Justin, Feng, Xidong, Varghese, Alison, Chrunyk, Boris A, Borzilleri, Kris, Hesp, Kevin D, Zhou, Kaihong, Ma, Nannan, Tu, Meihua, Dullea, Robert, McClure, Kim F, Wilson, Ross C, Liras, Spiros, Mascitti, Vincent, Doudna, Jennifer A
Published in Journal of the American Chemical Society (30.05.2018)
Published in Journal of the American Chemical Society (30.05.2018)
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Efficient Liver Targeting by Polyvalent Display of a Compact Ligand for the Asialoglycoprotein Receptor
Sanhueza, Carlos A, Baksh, Michael M, Thuma, Benjamin, Roy, Marc D, Dutta, Sanjay, Préville, Cathy, Chrunyk, Boris A, Beaumont, Kevin, Dullea, Robert, Ammirati, Mark, Liu, Shenping, Gebhard, David, Finley, James E, Salatto, Christopher T, King-Ahmad, Amanda, Stock, Ingrid, Atkinson, Karen, Reidich, Benjamin, Lin, Wen, Kumar, Rajesh, Tu, Meihua, Menhaji-Klotz, Elnaz, Price, David A, Liras, Spiros, Finn, M. G, Mascitti, Vincent
Published in Journal of the American Chemical Society (08.03.2017)
Published in Journal of the American Chemical Society (08.03.2017)
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An in vitro alveolar epithelial cell model recapitulates LRRK2 inhibitor-induced increases in lamellar body size observed in preclinical models
Harney, Julie, Bajaj, Piyush, Finley, James E., Kopec, Anna K., Koza-Taylor, Petra H., Boucher, Germaine G., Lanz, Thomas A., Doshna, Colleen M., Somps, Christopher J., Adkins, Karissa, Houle, Christopher
Published in Toxicology in vitro (01.02.2021)
Published in Toxicology in vitro (01.02.2021)
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Concentration-dependent modulation of amyloid-beta in vivo and in vitro using the gamma-secretase inhibitor, LY-450139
Lanz, Thomas A, Karmilowicz, Michael J, Wood, Kathleen M, Pozdnyakov, Nikolay, Du, Ping, Piotrowski, Mary A, Brown, Tracy M, Nolan, Charles E, Richter, Karl E G, Finley, James E, Fei, Qing, Ebbinghaus, Charles F, Chen, Yuhpyng L, Spracklin, Douglas K, Tate, Barbara, Geoghegan, Kieran F, Lau, Lit-Fui, Auperin, David D, Schachter, Joel B
Published in The Journal of pharmacology and experimental therapeutics (01.11.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2006)
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Pharmacodynamics and pharmacokinetics of the gamma-secretase inhibitor PF-3084014
Lanz, Thomas A, Wood, Kathleen M, Richter, Karl E G, Nolan, Charles E, Becker, Stacey L, Pozdnyakov, Nikolay, Martin, Barbara-Anne, Du, Ping, Oborski, Christine E, Wood, Douglas E, Brown, Tracy M, Finley, James E, Sokolowski, Sharon A, Hicks, Carol D, Coffman, Karen J, Geoghegan, Kieran F, Brodney, Michael A, Liston, Dane, Tate, Barbara
Published in The Journal of pharmacology and experimental therapeutics (01.07.2010)
Published in The Journal of pharmacology and experimental therapeutics (01.07.2010)
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Design, synthesis, and in vivo characterization of a novel series of tetralin amino imidazoles as γ-secretase inhibitors: Discovery of PF-3084014
Brodney, Michael A., Auperin, David D., Becker, Stacey L., Bronk, Brian S., Brown, Tracy M., Coffman, Karen J., Finley, James E., Hicks, Carol D., Karmilowicz, Michael J., Lanz, Thomas A., Liston, Dane, Liu, Xingrong, Martin, Barbara-Anne, Nelson, Robert B., Nolan, Charles E., Oborski, Christine E., Parker, Christine P., Richter, Karl E.G., Pozdnyakov, Nikolay, Sahagan, Barbara G., Schachter, Joel B., Sokolowski, Sharon A., Tate, Barbara, Wood, Douglas E., Wood, Kathleen M., Van Deusen, Jeffrey W., Zhang, Lei
Published in Bioorganic & medicinal chemistry letters (01.05.2011)
Published in Bioorganic & medicinal chemistry letters (01.05.2011)
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Diamide amino-imidazoles: A novel series of γ-secretase inhibitors for the treatment of Alzheimer’s disease
Brodney, Michael A., Auperin, David D., Becker, Stacey L., Bronk, Brian S., Brown, Tracy M., Coffman, Karen J., Finley, James E., Hicks, Carol D., Karmilowicz, Michael J., Lanz, Thomas A., Liston, Dane, Liu, Xingrong, Martin, Barbara-Anne, Nelson, Robert B., Nolan, Charles E., Oborski, Christine E., Parker, Christine P., Richter, Karl E.G., Pozdnyakov, Nikolay, Sahagan, Barbara G., Schachter, Joel B., Sokolowski, Sharon A., Tate, Barbara, Van Deusen, Jeffrey W., Wood, Douglas E., Wood, Kathleen M.
Published in Bioorganic & medicinal chemistry letters (01.05.2011)
Published in Bioorganic & medicinal chemistry letters (01.05.2011)
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Dendritic spine density deficits in the hippocampal CA1 region of young Tg2576 mice are ameliorated with the PDE9A inhibitor PF-04447943
Kleiman, Robin J, Lanz, Thomas A, Finley, James E, Bove, Susan E, Majchrzak, Mark J, Becker, Stacey L, Carvajal-Gonzales, Santos, Kuhn, A. Max, Wood, Kathleen M, Mariga, Abigail, Nelson, Frederick R, Verhoest, Patrick R, Seymour, Patricia A, Stephenson, Diane T
Published in Alzheimer's & dementia (01.07.2010)
Published in Alzheimer's & dementia (01.07.2010)
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P2-375: Efficacy of the novel γ-secretase inhibitor, PF-3084014, in reducing Aβ in brain, CSF, and plasma in guinea pigs and Tg2576 mice
Wood, Kathleen M, Lanz, Thomas A, Coffman, Karen J, Becker, Stacey L, van Deusen, Jeffrey, Nolan, Charles E, Richter, Karl E.G, Finley, James E, Brown, Tracey M, Brodney, Michael A, Tate, Barbara
Published in Alzheimer's & dementia (01.07.2008)
Published in Alzheimer's & dementia (01.07.2008)
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P3‐380: Dendritic spine density deficits in the hippocampal CA1 region of young Tg2576 mice are ameliorated with the PDE9A inhibitor PF‐04447943
Kleiman, Robin J., Lanz, Thomas A., Finley, James E., Bove, Susan E., Majchrzak, Mark J., Becker, Stacey L., Carvajal-Gonzales, Santos, Kuhn, A. Max, Wood, Kathleen M., Mariga, Abigail, Nelson, Frederick R., Verhoest, Patrick R., Seymour, Patricia A., Stephenson, Diane T.
Published in Alzheimer's & dementia (01.07.2010)
Published in Alzheimer's & dementia (01.07.2010)
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Concentration-Dependent Modulation of Amyloid-β in Vivo and in Vitro Using the γ-Secretase Inhibitor, LY-450139
Thomas A. Lanz, Michael J. Karmilowicz, Kathleen M. Wood, Nikolay Pozdnyakov, Ping Du, Mary A. Piotrowski, Tracy M. Brown, Charles E. Nolan, Karl E. G. Richter, James E. Finley, Qing Fei, Charles F. Ebbinghaus, Yuhpyng L. Chen, Douglas K. Spracklin, Barbara Tate, Kieran F. Geoghegan, Lit-Fui Lau, David D. Auperin, Joel B. Schachter
Published in The Journal of pharmacology and experimental therapeutics (01.11.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2006)
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Growth factors as potential drugs for the sensory epithelia of the ear
Corwin, J T, Warchol, M E, Saffer, L D, Finley, J E, Gu, R, Lamber, P R
Published in Ciba Foundation symposium (1996)
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Published in Ciba Foundation symposium (1996)
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