Biological Mechanisms and Clinical Significance of BAP1 Mutations in Human Cancer
Carbone, Michele, Harbour, J William, Brugarolas, James, Bononi, Angela, Pagano, Ian, Dey, Anwesha, Krausz, Thomas, Pass, Harvey I, Yang, Haining, Gaudino, Giovanni
Published in Cancer discovery (01.08.2020)
Published in Cancer discovery (01.08.2020)
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Effects on survival of BAP1 and PBRM1 mutations in sporadic clear-cell renal-cell carcinoma: a retrospective analysis with independent validation
Kapur, Payal, MD, Peña-Llopis, Samuel, PhD, Christie, Alana, MS, Zhrebker, Leah, MD, Pavía-Jiménez, Andrea, BS, Rathmell, W Kimryn, MD, Xie, Xian-Jin, PhD, Brugarolas, James, Dr
Published in The lancet oncology (01.02.2013)
Published in The lancet oncology (01.02.2013)
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Establishing a human renal cell carcinoma tumorgraft platform for preclinical drug testing
Pavía-Jiménez, Andrea, Tcheuyap, Vanina Toffessi, Brugarolas, James
Published in Nature protocols (01.08.2014)
Published in Nature protocols (01.08.2014)
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Spectrum of diverse genomic alterations define non–clear cell renal carcinoma subtypes
Durinck, Steffen, Stawiski, Eric W, Pavía-Jiménez, Andrea, Modrusan, Zora, Kapur, Payal, Jaiswal, Bijay S, Zhang, Na, Toffessi-Tcheuyap, Vanina, Nguyen, Thong T, Pahuja, Kanika Bajaj, Chen, Ying-Jiun, Saleem, Sadia, Chaudhuri, Subhra, Heldens, Sherry, Jackson, Marlena, Peña-Llopis, Samuel, Guillory, Joseph, Toy, Karen, Ha, Connie, Harris, Corissa J, Holloman, Eboni, Hill, Haley M, Stinson, Jeremy, Rivers, Celina Sanchez, Janakiraman, Vasantharajan, Wang, Weiru, Kinch, Lisa N, Grishin, Nick V, Haverty, Peter M, Chow, Bernard, Gehring, Julian S, Reeder, Jens, Pau, Gregoire, Wu, Thomas D, Margulis, Vitaly, Lotan, Yair, Sagalowsky, Arthur, Pedrosa, Ivan, de Sauvage, Frederic J, Brugarolas, James, Seshagiri, Somasekar
Published in Nature genetics (2015)
Published in Nature genetics (2015)
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Familial Kidney Cancer: Implications of New Syndromes and Molecular Insights
Carlo, Maria I., Hakimi, A. Ari, Stewart, Grant D., Bratslavsky, Gennady, Brugarolas, James, Chen, Ying-Bei, Linehan, W. Marston, Maher, Eamonn R., Merino, Maria J., Offit, Kenneth, Reuter, Victor E., Shuch, Brian, Coleman, Jonathan A.
Published in European urology (01.12.2019)
Published in European urology (01.12.2019)
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Stereotactic Ablative Radiation Therapy (SAbR) Used to Defer Systemic Therapy in Oligometastatic Renal Cell Cancer
Zhang, Yuanyuan, Schoenhals, Jonathan, Christie, Alana, Mohamad, Osama, Wang, Chiachien, Bowman, Isaac, Singla, Nirmish, Hammers, Hans, Courtney, Kevin, Bagrodia, Aditya, Margulis, Vitaly, Desai, Neil, Garant, Aurelie, Choy, Hak, Timmerman, Robert, Brugarolas, James, Hannan, Raquibul
Published in International journal of radiation oncology, biology, physics (01.10.2019)
Published in International journal of radiation oncology, biology, physics (01.10.2019)
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Safety and Efficacy of Stereotactic Ablative Radiation Therapy for Renal Cell Carcinoma Extracranial Metastases
Wang, Chiachien Jake, MD, PhD, Christie, Alana, MS, Lin, Mu-Han, PhD, Jung, Matthew, BS, Weix, Derek, BS, Huelsmann, Lorel, BS, Kuhn, Kristin, MD, Meyer, Jeffrey, MD, MS, Desai, Neil, MD, Kim, D. W. Nathan, MD, PhD, Pedrosa, Ivan, MD, Margulis, Vitaly, MD, Cadeddu, Jeffrey, MD, Sagalowsky, Arthur, MD, Gahan, Jeffrey, MD, Laine, Aaron, MD, PhD, Xie, Xian-Jin, PhD, Choy, Hak, MD, Brugarolas, James, MD, PhD, Timmerman, Robert, MD, Hannan, Raquibul, MD, PhD
Published in International journal of radiation oncology, biology, physics (01.05.2017)
Published in International journal of radiation oncology, biology, physics (01.05.2017)
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An Empirical Approach Leveraging Tumorgrafts to Dissect the Tumor Microenvironment in Renal Cell Carcinoma Identifies Missing Link to Prognostic Inflammatory Factors
Wang, Tao, Lu, Rong, Kapur, Payal, Jaiswal, Bijay S, Hannan, Raquibul, Zhang, Ze, Pedrosa, Ivan, Luke, Jason J, Zhang, He, Goldstein, Leonard D, Yousuf, Qurratulain, Gu, Yi-Feng, McKenzie, Tiffani, Joyce, Allison, Kim, Min S, Wang, Xinlei, Luo, Danni, Onabolu, Oreoluwa, Stevens, Christina, Xie, Zhiqun, Chen, Mingyi, Filatenkov, Alexander, Torrealba, Jose, Luo, Xin, Guo, Wenbin, He, Jingxuan, Stawiski, Eric, Modrusan, Zora, Durinck, Steffen, Seshagiri, Somasekar, Brugarolas, James
Published in Cancer discovery (01.09.2018)
Published in Cancer discovery (01.09.2018)
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Germline and sporadic mTOR pathway mutations in low-grade oncocytic tumor of the kidney
Kapur, Payal, Gao, Ming, Zhong, Hua, Chintalapati, Suneetha, Mitui, Midori, Barnes, Spencer D., Zhou, Qinbo, Miyata, Jeffrey, Carrillo, Deyssy, Malladi, Venkat S., Rakheja, Dinesh, Pedrosa, Ivan, Xu, Lin, Kinch, Lisa, Brugarolas, James
Published in Modern pathology (01.03.2022)
Published in Modern pathology (01.03.2022)
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Modeling Renal Cell Carcinoma in Mice: Bap1 and Pbrm1 Inactivation Drive Tumor Grade
Gu, Yi-Feng, Cohn, Shannon, Christie, Alana, McKenzie, Tiffani, Wolff, Nicholas, Do, Quyen N, Madhuranthakam, Ananth J, Pedrosa, Ivan, Wang, Tao, Dey, Anwesha, Busslinger, Meinrad, Xie, Xian-Jin, Hammer, Robert E, McKay, Renée M, Kapur, Payal, Brugarolas, James
Published in Cancer discovery (01.08.2017)
Published in Cancer discovery (01.08.2017)
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Cooperation and Antagonism among Cancer Genes: The Renal Cancer Paradigm
PENA-LLOPIS, Samuel, CHRISTIE, Alana, XIE, Xian-Jin, BRUGAROLAS, James
Published in Cancer research (Chicago, Ill.) (15.07.2013)
Published in Cancer research (Chicago, Ill.) (15.07.2013)
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SCINA: A Semi-Supervised Subtyping Algorithm of Single Cells and Bulk Samples
Zhang, Ze, Luo, Danni, Zhong, Xue, Choi, Jin Huk, Ma, Yuanqing, Wang, Stacy, Mahrt, Elena, Guo, Wei, Stawiski, Eric W, Modrusan, Zora, Seshagiri, Somasekar, Kapur, Payal, Hon, Gary C, Brugarolas, James, Wang, Tao
Published in Genes (12.07.2019)
Published in Genes (12.07.2019)
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Bap1 is essential for kidney function and cooperates with Vhl in renal tumorigenesis
Wang, Shan-Shan, Gu, Yi-Feng, Wolff, Nicholas, Stefanius, Karoliina, Christie, Alana, Dey, Anwesha, Hammer, Robert E., Xie, Xian-Jin, Rakheja, Dinesh, Pedrosa, Ivan, Carroll, Thomas, McKay, Renée M., Kapur, Payal, Brugarolas, James
Published in Proceedings of the National Academy of Sciences - PNAS (18.11.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (18.11.2014)
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Determinants of renal cell carcinoma invasion and metastatic competence
Kim, Kangsan, Zhou, Qinbo, Christie, Alana, Stevens, Christina, Ma, Yuanqing, Onabolu, Oreoluwa, Chintalapati, Suneetha, Mckenzie, Tiffani, Tcheuyap, Vanina Toffessi, Woolford, Layton, Zhang, He, Singla, Nirmish, Parida, Pravat Kumar, Marquez-Palencia, Mauricio, Pedrosa, Ivan, Margulis, Vitaly, Sagalowsky, Arthur, Xie, Zhiqun, Wang, Tao, Durinck, Steffen, Modrusan, Zora, Seshagiri, Somasekar, Kapur, Payal, Brugarolas, James, Malladi, Srinivas
Published in Nature communications (04.10.2021)
Published in Nature communications (04.10.2021)
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PML restrains p53 activity and cellular senescence in clear cell renal cell carcinoma
Simoni, Matilde, Menegazzi, Chiara, Fracassi, Cristina, Biffi, Claudia C, Genova, Francesca, Tenace, Nazario Pio, Lucianò, Roberta, Raimondi, Andrea, Tacchetti, Carlo, Brugarolas, James, Mazza, Davide, Bernardi, Rosa
Published in EMBO molecular medicine (14.06.2024)
Published in EMBO molecular medicine (14.06.2024)
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Pathologic response and surgical outcomes in patients undergoing nephrectomy following receipt of immune checkpoint inhibitors for renal cell carcinoma
Singla, Nirmish, Elias, Roy, Ghandour, Rashed A., Freifeld, Yuval, Bowman, Isaac A., Rapoport, Leonid, Enikeev, Mikhail, Lohrey, Jay, Woldu, Solomon L., Gahan, Jeffrey C., Bagrodia, Aditya, Brugarolas, James, Hammers, Hans J., Margulis, Vitaly
Published in Urologic oncology (01.12.2019)
Published in Urologic oncology (01.12.2019)
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