Edge chipping and flexural resistance of monolithic ceramics
Zhang, Yu, Lee, James J.-W, Srikanth, Ramanathan, Lawn, Brian R
Published in Dental materials (01.12.2013)
Published in Dental materials (01.12.2013)
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Remarkable resilience of teeth
Chai, Herzl, Lee, James J.-W, Constantino, Paul J, Lucas, Peter W, Lawn, Brian R
Published in Proceedings of the National Academy of Sciences - PNAS (05.05.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (05.05.2009)
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On the interfacial fracture of porcelain/zirconia and graded zirconia dental structures
Chai, Herzl, Lee, James J.-W., Mieleszko, Adam J., Chu, Stephen J., Zhang, Yu
Published in Acta biomaterialia (01.08.2014)
Published in Acta biomaterialia (01.08.2014)
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Tooth chipping can reveal the diet and bite forces of fossil hominins
Constantino, Paul J., Lee, James J.-W., Chai, Herzl, Zipfel, Bernhard, Ziscovici, Charles, Lawn, Brian R., Lucas, Peter W.
Published in Biology letters (2005) (23.12.2010)
Published in Biology letters (2005) (23.12.2010)
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Rationally Designed, Conformationally Constrained Inverse Agonists of RORγtIdentification of a Potent, Selective Series with Biologic-Like in Vivo Efficacy
Marcoux, David, Duan, James J.-W, Shi, Qing, Cherney, Robert J, Srivastava, Anurag S, Cornelius, Lyndon, Batt, Douglas G, Liu, Qingjie, Beaudoin-Bertrand, Myra, Weigelt, Carolyn A, Khandelwal, Purnima, Vishwakrishnan, Sureshbabu, Selvakumar, Kumaravel, Karmakar, Ananta, Gupta, Arun Kumar, Basha, Mushkin, Ramlingam, Sridharan, Manjunath, Naveen, Vanteru, Sridhar, Karmakar, Sukhen, Maddala, Nageswara, Vetrichelvan, Muthalagu, Gupta, Anuradha, Rampulla, Richard A, Mathur, Arvind, Yip, Shiuhang, Li, Peng, Wu, Dauh-Rurng, Khan, Javed, Ruzanov, Max, Sack, John S, Wang, Jinhong, Yarde, Melissa, Cvijic, Mary Ellen, Li, Sha, Shuster, David J, Borowski, Virna, Xie, Jenny H, McIntyre, Kim W, Obermeier, Mary T, Fura, Aberra, Stefanski, Kevin, Cornelius, Georgia, Hynes, John, Tino, Joseph A, Macor, John E, Salter-Cid, Luisa, Denton, Rex, Zhao, Qihong, Carter, Percy H, Dhar, T. G. Murali
Published in Journal of medicinal chemistry (14.11.2019)
Published in Journal of medicinal chemistry (14.11.2019)
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The influence of fallback foods on great ape tooth enamel
Constantino, Paul J., Lucas, Peter W., Lee, James J.-W., Lawn, Brian R.
Published in American journal of physical anthropology (01.12.2009)
Published in American journal of physical anthropology (01.12.2009)
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Conference Proceeding
Structure-based Discovery of Phenyl (3-Phenylpyrrolidin-3-yl)sulfones as Selective, Orally Active RORγt Inverse Agonists
Duan, James J.-W, Lu, Zhonghui, Jiang, Bin, Stachura, Sylwia, Weigelt, Carolyn A, Sack, John S, Khan, Javed, Ruzanov, Max, Galella, Michael A, Wu, Dauh-Rurng, Yarde, Melissa, Shen, Ding-Ren, Shuster, David J, Borowski, Virna, Xie, Jenny H, Zhang, Lisa, Vanteru, Sridhar, Gupta, Arun Kumar, Mathur, Arvind, Zhao, Qihong, Foster, William, Salter-Cid, Luisa M, Carter, Percy H, Dhar, T. G. Murali
Published in ACS medicinal chemistry letters (14.03.2019)
Published in ACS medicinal chemistry letters (14.03.2019)
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Frnakenstein: multiple target inverse RNA folding
Lyngsø, Rune B, Anderson, James W J, Sizikova, Elena, Badugu, Amarendra, Hyland, Tomas, Hein, Jotun
Published in BMC bioinformatics (09.10.2012)
Published in BMC bioinformatics (09.10.2012)
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Biologic-like In Vivo Efficacy with Small Molecule Inhibitors of TNFα Identified Using Scaffold Hopping and Structure-Based Drug Design Approaches
Xiao, Hai-Yun, Li, Ning, Duan, James J.-W, Jiang, Bin, Lu, Zhonghui, Ngu, Khehyong, Tino, Joseph, Kopcho, Lisa M, Lu, Hao, Chen, Jing, Tebben, Andrew J, Sheriff, Steven, Chang, ChiehYing Y, Yanchunas, Joseph, Calambur, Deepa, Gao, Mian, Shuster, David J, Susulic, Vojkan, Xie, Jenny H, Guarino, Victor R, Wu, Dauh-Rurng, Gregor, Kurt R, Goldstine, Christine B, Hynes, John, Macor, John E, Salter-Cid, Luisa, Burke, James R, Shaw, Patrick J, Dhar, T. G. Murali
Published in Journal of medicinal chemistry (10.12.2020)
Published in Journal of medicinal chemistry (10.12.2020)
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Identification of bicyclic hexafluoroisopropyl alcohol sulfonamides as retinoic acid receptor-related orphan receptor gamma (RORγ/RORc) inverse agonists. Employing structure-based drug design to improve pregnane X receptor (PXR) selectivity
Gong, Hua, Weinstein, David S., Lu, Zhonghui, Duan, James J.-W., Stachura, Sylwia, Haque, Lauren, Karmakar, Ananta, Hemagiri, Hemalatha, Raut, Dhanya Kumar, Gupta, Arun Kumar, Khan, Javed, Camac, Dan, Sack, John S., Pudzianowski, Andrew, Wu, Dauh-Rurng, Yarde, Melissa, Shen, Ding-Ren, Borowski, Virna, Xie, Jenny H., Sun, Huadong, D'Arienzo, Celia, Dabros, Marta, Galella, Michael A., Wang, Faye, Weigelt, Carolyn A., Zhao, Qihong, Foster, William, Somerville, John E., Salter-Cid, Luisa M., Barrish, Joel C., Carter, Percy H., Dhar, T.G. Murali
Published in Bioorganic & medicinal chemistry letters (15.01.2018)
Published in Bioorganic & medicinal chemistry letters (15.01.2018)
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Adaptation to hard-object feeding in sea otters and hominins
Constantino, Paul J., Lee, James J.-W., Morris, Dylan, Lucas, Peter W., Hartstone-Rose, Adam, Lee, Wah-Keat, Dominy, Nathaniel J., Cunningham, Andrew, Wagner, Mark, Lawn, Brian R.
Published in Journal of human evolution (01.07.2011)
Published in Journal of human evolution (01.07.2011)
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Melanoma Mediated Disruption of Brain Endothelial Barrier Integrity Is Not Prevented by the Inhibition of Matrix Metalloproteinases and Proteases
Anchan, Akshata, Finlay, Graeme, Angel, Catherine E, Hucklesby, James J. W, Graham, Scott E
Published in Biosensors (Basel) (19.08.2022)
Published in Biosensors (Basel) (19.08.2022)
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The role of tooth enamel mechanical properties in primate dietary adaptation
Constantino, Paul J., Lee, James J.-W., Gerbig, Yvonne, Hartstone-Rose, Adam, Talebi, Mauricio, Lawn, Brian R., Lucas, Peter W.
Published in American journal of physical anthropology (01.06.2012)
Published in American journal of physical anthropology (01.06.2012)
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Journal Article
Conference Proceeding
Discovery of (3S,4S)-3-methyl-3-(4-fluorophenyl)-4-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxyprop-2-yl)phenyl)pyrrolidines as novel RORγt inverse agonists
Jiang, Bin, Duan, James J.-W., Stachura, Sylwia, Karmakar, Ananta, Hemagiri, Hemalatha, Raut, Dhanya Kumar, Gupta, Arun Kumar, Weigelt, Carolyn A., Khan, Javed, Sack, John S., Wu, Dauh-Rurng, Yarde, Melissa, Shen, Ding-Ren, Galella, Michael A., Mathur, Arvind, Zhao, Qihong, Salter-Cid, Luisa M., Carter, Percy H., Dhar, T.G. Murali
Published in Bioorganic & medicinal chemistry letters (01.09.2020)
Published in Bioorganic & medicinal chemistry letters (01.09.2020)
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Analysis of Melanoma Secretome for Factors That Directly Disrupt the Barrier Integrity of Brain Endothelial Cells
Anchan, Akshata, Martin, Olivia, Hucklesby, James J W, Finlay, Graeme, Johnson, Rebecca H, Robilliard, Laverne D, O'Carroll, Simon J, Angel, Catherine E, Graham, E Scott
Published in International journal of molecular sciences (01.11.2020)
Published in International journal of molecular sciences (01.11.2020)
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Discovery of highly potent, selective, covalent inhibitors of JAK3
Kempson, James, Ovalle, Damaso, Guo, Junqing, Wrobleski, Stephen T., Lin, Shuqun, Spergel, Steven H., Duan, James J.-W., Jiang, Bin, Lu, Zhonghui, Das, Jagabandhu, Yang, Bingwei V., Hynes, John, Wu, Hong, Tokarski, John, Sack, John S., Khan, Javed, Schieven, Gary, Blatt, Yuval, Chaudhry, Charu, Salter-Cid, Luisa M., Fura, Aberra, Barrish, Joel C., Carter, Percy H., Pitts, William J.
Published in Bioorganic & medicinal chemistry letters (15.10.2017)
Published in Bioorganic & medicinal chemistry letters (15.10.2017)
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Journal Article
On the chipping and splitting of teeth
Chai, Herzl, Lee, James J.-W., Lawn, Brian R.
Published in Journal of the mechanical behavior of biomedical materials (01.04.2011)
Published in Journal of the mechanical behavior of biomedical materials (01.04.2011)
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Journal Article
Comparison of Leading Biosensor Technologies to Detect Changes in Human Endothelial Barrier Properties in Response to Pro-Inflammatory TNFα and IL1β in Real-Time
Hucklesby, James J. W., Anchan, Akshata, O'Carroll, Simon J., Unsworth, Charles P., Graham, E. Scott, Angel, Catherine E.
Published in Biosensors (Basel) (18.05.2021)
Published in Biosensors (Basel) (18.05.2021)
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