ID2 and HIF-1α collaborate to protect quiescent hematopoietic stem cells from activation, differentiation, and exhaustion
Jakubison, Brad L., Sarkar, Tanmoy, Gudmundsson, Kristbjorn O., Singh, Shweta, Sun, Lei, Morris, Holly M., Klarmann, Kimberly D., Keller, Jonathan R.
Published in The Journal of clinical investigation (01.07.2022)
Published in The Journal of clinical investigation (01.07.2022)
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Inhibitor of DNA binding proteins revealed as orchestrators of steady state, stress and malignant hematopoiesis
Singh, Shweta, Sarkar, Tanmoy, Jakubison, Brad, Gadomski, Stephen, Spradlin, Andrew, Gudmundsson, Kristbjorn O., Keller, Jonathan R.
Published in Frontiers in immunology (05.08.2022)
Published in Frontiers in immunology (05.08.2022)
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Id1 and Id3 Maintain Steady-State Hematopoiesis by Promoting Sinusoidal Endothelial Cell Survival and Regeneration
Gadomski, Stephen, Singh, Satyendra K., Singh, Shweta, Sarkar, Tanmoy, Klarmann, Kimberly D., Berenschot, Maximillian, Seaman, Steven, Jakubison, Brad, Gudmundsson, Kristbjorn O., Lockett, Stephen, Keller, Jonathan R.
Published in Cell reports (Cambridge) (28.04.2020)
Published in Cell reports (Cambridge) (28.04.2020)
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The basic helix-loop-helix transcription factor E47 reprograms human pancreatic cancer cells to a quiescent acinar state with reduced tumorigenic potential
Kim, SangWun, Lahmy, Reyhaneh, Riha, Chelsea, Yang, Challeng, Jakubison, Brad L, van Niekerk, Jaco, Staub, Claudio, Wu, Yifan, Gates, Keith, Dong, Duc Si, Konieczny, Stephen F, Itkin-Ansari, Pamela
Published in Pancreas (01.07.2015)
Published in Pancreas (01.07.2015)
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Induced PTF1a expression in pancreatic ductal adenocarcinoma cells activates acinar gene networks, reduces tumorigenic properties, and sensitizes cells to gemcitabine treatment
Jakubison, Brad L., Schweickert, Patrick G., Moser, Sarah E., Yang, Yi, Gao, Hongyu, Scully, Kathleen, Itkin‐Ansari, Pamela, Liu, Yunlong, Konieczny, Stephen F.
Published in Molecular oncology (01.06.2018)
Published in Molecular oncology (01.06.2018)
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Induced PTF 1a expression in pancreatic ductal adenocarcinoma cells activates acinar gene networks, reduces tumorigenic properties, and sensitizes cells to gemcitabine treatment
Jakubison, Brad L., Schweickert, Patrick G., Moser, Sarah E., Yang, Yi, Gao, Hongyu, Scully, Kathleen, Itkin‐Ansari, Pamela, Liu, Yunlong, Konieczny, Stephen F.
Published in Molecular oncology (01.06.2018)
Published in Molecular oncology (01.06.2018)
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Protection of hematopoietic stem cells from stress-induced exhaustion and aging
Singh, Shweta, Jakubison, Brad, Keller, Jonathan R
Published in Current opinion in hematology (01.07.2020)
Published in Current opinion in hematology (01.07.2020)
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Journal Article
ID2 and HIF-1[alpha] collaborate to protect quiescent hematopoietic stem cells from activation, differentiation, and exhaustion
Jakubison, Brad L, Sarkar, Tanmoy, Gudmundsson, Kristbjorn O, Singh, Shweta, Sun, Lei, Morris, Holly M, Klarmann, Kimberly D, Keller, Jonathan R
Published in The Journal of clinical investigation (01.07.2022)
Published in The Journal of clinical investigation (01.07.2022)
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Journal Article
First Disclosure of AZD9829, a TOP1i-ADC Targeting CD123: Promising Preclinical Activity in AML Models with Minimal Effect on Healthy Progenitors
Dutta, Dipannita, Pan, Pan, Fleming, Ryan, Andrade-Campos, Marcio, Belova, Elena, Wheeler, Jennifer, Cheung, Patricia, Santacroce, Paul, Daniels, Casey, Sabol, Darrin, Jakubison, Brad, Recolin, Benedicte, Dippel, Andrew, Wey, Margaret, Shaffer, Arthur, Rosfjord, Edward, Hurt, Elaine, Gorgun, Gullu, Younes, Anas, Sapra, Puja
Published in Blood (02.11.2023)
Published in Blood (02.11.2023)
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Abstract A13: Mechanisms of E47 induced quiescence and acinar cell differentiation in human pancreatic cancer cells
Kim, Sangwun, Yang, Challeng, Riha, Chelsea, Lamy, Reyhaneh, Jakubison, Brad L., Konieczny, Stephen F., Itkin-Ansari, Pamela
Published in Cancer research (Chicago, Ill.) (01.07.2015)
Published in Cancer research (Chicago, Ill.) (01.07.2015)
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