Discovery of indoximod prodrugs and characterization of clinical candidate NLG802
Kumar, Sanjeev, Jaipuri, Firoz A., Waldo, Jesse P., Potturi, Hima, Marcinowicz, Agnieszka, Adams, James, Van Allen, Clarissa, Zhuang, Hong, Vahanian, Nicholas, Link, Charles, Brincks, Erik L., Mautino, Mario R.
Published in European journal of medicinal chemistry (15.07.2020)
Published in European journal of medicinal chemistry (15.07.2020)
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Journal Article
Fluorous-Based Carbohydrate Microarrays
Ko, Kwang-Seuk, Jaipuri, Firoz A, Pohl, Nicola L
Published in Journal of the American Chemical Society (28.09.2005)
Published in Journal of the American Chemical Society (28.09.2005)
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Journal Article
Implementation of the CYP Index for the Design of Selective Tryptophan-2,3-dioxygenase Inhibitors
Parr, Brendan T, Pastor, Richard, Sellers, Benjamin D, Pei, Zhonghua, Jaipuri, Firoz A, Castanedo, Georgette M, Gazzard, Lewis, Kumar, Sanjeev, Li, Xiaokai, Liu, Wen, Mendonca, Rohan, Pavana, Roheeth K, Potturi, Hima, Shao, Cheng, Velvadapu, Venkata, Waldo, Jesse P, Wu, Guosheng, Yuen, Po-wai, Zhang, Zuhui, Zhang, Yamin, Harris, Seth F, Oh, Angela J, DiPasquale, Antonio, Dement, Kevin, La, Hank, Goon, Leanne, Gustafson, Amy, VanderPorten, Erica C, Mautino, Mario R, Liu, Yichin
Published in ACS medicinal chemistry letters (09.04.2020)
Published in ACS medicinal chemistry letters (09.04.2020)
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Journal Article
Discovery of Clinical Candidate (1 R ,4 r )-4-(( R )-2-(( S )-6-Fluoro-5 H -imidazo[5,1- a ]isoindol-5-yl)-1-hydroxyethyl)cyclohexan-1-ol (Navoximod), a Potent and Selective Inhibitor of Indoleamine 2,3-Dioxygenase 1
Kumar, Sanjeev, Waldo, Jesse P, Jaipuri, Firoz A, Marcinowicz, Agnieszka, Van Allen, Clarissa, Adams, James, Kesharwani, Tanay, Zhang, Xiaoxia, Metz, Richard, Oh, Angela J, Harris, Seth F, Mautino, Mario R
Published in Journal of medicinal chemistry (25.07.2019)
Published in Journal of medicinal chemistry (25.07.2019)
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Journal Article
Synthesis of 6,6′-Binaphthopyran-2-one Natural Products: Pigmentosin A, Talaroderxines A and B
Grove, Charles I, Di Maso, Michael J, Jaipuri, Firoz A, Kim, Michelle B, Shaw, Jared T
Published in Organic letters (07.09.2012)
Published in Organic letters (07.09.2012)
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Journal Article
Identification of the Molecular Target of Small Molecule Inhibitors of HDL Receptor SR-BI Activity
Nieland, Thomas J. F, Shaw, Jared T, Jaipuri, Firoz A, Duffner, Jay L, Koehler, Angela N, Banakos, Sotirios, Zannis, Vassilis I, Kirchhausen, Tomas, Krieger, Monty
Published in Biochemistry (Easton) (08.01.2008)
Published in Biochemistry (Easton) (08.01.2008)
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Journal Article
Discovery of Clinical Candidate (1R,4r)‑4-((R)‑2-((S)‑6-Fluoro‑5H‑imidazo[5,1‑a]isoindol-5-yl)-1-hydroxyethyl)cyclohexan-1-ol (Navoximod), a Potent and Selective Inhibitor of Indoleamine 2,3-Dioxygenase 1
Kumar, Sanjeev, Waldo, Jesse P, Jaipuri, Firoz A, Marcinowicz, Agnieszka, Van Allen, Clarissa, Adams, James, Kesharwani, Tanay, Zhang, Xiaoxia, Metz, Richard, Oh, Angela J, Harris, Seth F, Mautino, Mario R
Published in Journal of medicinal chemistry (25.07.2019)
Published in Journal of medicinal chemistry (25.07.2019)
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Journal Article
Influence of HDL-cholesterol-elevating drugs on the in vitro activity of the HDL receptor SR-BI
Nieland, Thomas J.F., Shaw, Jared T., Jaipuri, Firoz A., Maliga, Zoltan, Duffner, Jay L., Koehler, Angela N., Krieger, Monty
Published in Journal of lipid research (01.08.2007)
Published in Journal of lipid research (01.08.2007)
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Journal Article
Noncovalent fluorous interactions for the synthesis of carbohydrate microarrays
Mamidyala, Sreeman K., Ko, Kwang-Seuk, Jaipuri, Firoz A., Park, Gisun, Pohl, Nicola L.
Published in Journal of fluorine chemistry (01.05.2006)
Published in Journal of fluorine chemistry (01.05.2006)
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Journal Article
Discovery of Clinical Candidate (1R,4r)-44(R)-24(S)-6-Fluoro-5H-imidazo[5,1-a]isoindol-5-yl)-1-hydroxyethyl)cyclohexan-1-ol (Navoximod), a Potent and Selective Inhibitor of Indoleamine 2,3-Dioxygenase 1
Kumar, Sanjeev, Waldo, Jesse P., Jaipuri, Firoz A., Marcinowicz, Agnieszka, Van Allen, Clarissa, Adams, James, Kesharwani, Tanay, Zhang, Xiaoxia, Metz, Richard, Oh, Angela J., Harris, Seth F., Mautino, Mario R.
Published in Journal of medicinal chemistry (25.07.2019)
Published in Journal of medicinal chemistry (25.07.2019)
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Journal Article
Abstract 2043: Synthetic lethality of PARG inhibition in tumors with homologous recombination deficiencies
Abed, Monah, Munoz, Diana, Jaipuri, Firoz, Ravindran, Nandini, Seshadri, Vidya, Liimatta, Marya, Neilan, Claire, Linghu, Xin, Nguyen, An, Wagle, Marie-Claire, Mounir, Zineb
Published in Cancer research (Chicago, Ill.) (01.07.2021)
Published in Cancer research (Chicago, Ill.) (01.07.2021)
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Journal Article
Discovery of BMS-986339, a Pharmacologically Differentiated Farnesoid X Receptor Agonist for the Treatment of Nonalcoholic Steatohepatitis
Nara, Susheel J., Jogi, Srinivas, Cheruku, Srinivas, Kandhasamy, Sarkunam, Jaipuri, Firoz, Kathi, Pavan Kalyan, Reddy, Subba, Sarodaya, Sanket, Cook, Erica M., Wang, Tao, Sitkoff, Doree, Rossi, Karen A., Ruzanov, Max, Kiefer, Susan E., Khan, Javed A., Gao, Mian, Reddy, Satyanarayana, Sivaprasad LVJ, Sankara, Sane, Ramola, Mosure, Kathy, Zhuo, Xiaoliang, Cao, Gary G., Ziegler, Milinda, Azzara, Anthony, Krupinski, John, Soars, Matthew G., Ellsworth, Bruce A., Wacker, Dean A.
Published in Journal of medicinal chemistry (14.07.2022)
Published in Journal of medicinal chemistry (14.07.2022)
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Journal Article
Abstract 4076: A novel prodrug of indoximod with enhanced pharmacokinetic properties
Mautino, Mario R., Kumar, Sanjeev, Zhuang, Hong, Waldo, Jesse, Jaipuri, Firoz, Potturi, Hima, Brincks, Erik, Adams, James, Marcinowicz, Agnieszka, Allen, Clarissa Van, Vahanian, Nicholas, Link, Charles J.
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract 6093: IDE161, a potential first-in-class clinical candidate PARG inhibitor, selectively targets homologous-recombination-deficient and PARP inhibitor resistant breast and ovarian tumors
Abed, Monah, Muñoz, Diana, Seshadri, Vidya, Federowicz, Steve, Rao, Arjun A., Bhupathi, Deepthi, Liimatta, Marya, Ousterhout, Rita, Jaipuri, Firoz, Neilan, Claire, Lackner, Mark, White, Mike, Mounir, Zineb
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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