Differential Effects of Hypoxia versus Hyperoxia or Physoxia on Phenotype and Energy Metabolism in Human Chondrocytes from Osteoarthritic Compared to Macroscopically Normal Cartilage
Jain, Lekha, Bolam, Scott M, Monk, A Paul, Munro, Jacob T, Chen, Even, Tamatea, Jade, Dalbeth, Nicola, Poulsen, Raewyn C
Published in International journal of molecular sciences (01.04.2023)
Published in International journal of molecular sciences (01.04.2023)
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Journal Article
The growth hormone receptor interacts with transcriptional regulator HMGN1 upon GH-induced nuclear translocation
Jain, Lekha, Vickers, Mark H., Jacob, Bincy, Middleditch, Martin J., Chudakova, Daria A., Ganley, Austen R. D., O’Sullivan, Justin M., Perry, Jo K.
Published in Journal of cell communication and signaling (01.09.2023)
Published in Journal of cell communication and signaling (01.09.2023)
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Journal Article
Monosodium urate crystals alter the circadian clock in macrophages leading to loss of NLRP3 inflammasome repression: Implications for timing of the gout flare
Popov, Dmitry, Jain, Lekha, Alhilali, Mariam, Dalbeth, Nicola, Poulsen, Raewyn C.
Published in The FASEB journal (01.06.2023)
Published in The FASEB journal (01.06.2023)
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Journal Article
Elevated glucose promotes MMP13 and ADAMTS5 production by osteoarthritic chondrocytes under oxygenated but not hypoxic conditions
Jain, Lekha, Bolam, Scott M., Monk, Paul, Munro, Jacob T., Tamatea, Jade, Dalbeth, Nicola, Poulsen, Raewyn C.
Published in Journal of cellular physiology (01.06.2024)
Published in Journal of cellular physiology (01.06.2024)
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Phenotype and energy metabolism differ between osteoarthritic chondrocytes from male compared to female patients: Implications for sexual dimorphism in osteoarthritis development?
Jain, Lekha, Jardim, Caitlin A., Yulo, Richard, Bolam, Scott M., Monk, A. Paul, Munro, Jacob T., Pitto, Rocco, Tamatea, Jade, Dalbeth, Nicola, Poulsen, Raewyn C.
Published in Osteoarthritis and cartilage (01.09.2024)
Published in Osteoarthritis and cartilage (01.09.2024)
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Journal Article
REST, RCOR1 and RCOR2 expression is reduced in osteoarthritic chondrocytes and contributes to increasing MMP13 and ADAMTS5 expression through upregulating HES1
Primrose, Julia G.B., Jain, Lekha, Alhilali, Mariam, Bolam, Scott M., Monk, A. Paul, Munro, Jacob T., Dalbeth, Nicola, Poulsen, Raewyn C.
Published in Cellular signalling (01.09.2023)
Published in Cellular signalling (01.09.2023)
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Journal Article
Concentration-dependent effects of leptin on osteoarthritis-associated changes in phenotype of human chondrocytes
Primrose, Julia GB, Jain, Lekha, Bolam, Scott M, Monk, A Paul, Munro, Jacob T, Dalbeth, Nicola, Poulsen, Raewyn C
Published in Connective tissue research (03.09.2023)
Published in Connective tissue research (03.09.2023)
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Journal Article
OR01-04 The Growth Hormone Receptor Interacts With Transcriptional Regulator, HMGN1, Upon GH-induced Nuclear Translocation
Jain, Lekha, Vickers, Mark H, Jacob, Bincy, Middleditch, Martin J, Chudakova, Daria A, Ganley, Austen R D, O'Sullivan, Justin M, Perry, Jo K
Published in Journal of the Endocrine Society (05.10.2023)
Published in Journal of the Endocrine Society (05.10.2023)
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SAT-303 3D Mapping of the Human Growth Hormone Locus Identifies Putative Regulatory Hubs for Genes Involved in Cellular Signalling and Cancer-Related Pathways
Jain, Lekha, Fadason, Tayaza, Schierding, William, Vickers, Mark Hedley, O’Sullivan, Justin M, Perry, Jo Kate
Published in Journal of the Endocrine Society (08.05.2020)
Published in Journal of the Endocrine Society (08.05.2020)
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Journal Article