Liraglutide, 7,8-DHF and their co-treatment prevents loss of vision and cognitive decline in a Wolfram syndrome rat model
Seppa, Kadri, Jagomäe, Toomas, Kukker, Kaia Grete, Reimets, Riin, Pastak, Marko, Vasar, Eero, Terasmaa, Anton, Plaas, Mario
Published in Scientific reports (26.01.2021)
Published in Scientific reports (26.01.2021)
Get full text
Journal Article
Preventive treatment with liraglutide protects against development of glucose intolerance in a rat model of Wolfram syndrome
Toots, Maarja, Seppa, Kadri, Jagomäe, Toomas, Koppel, Tuuliki, Pallase, Maia, Heinla, Indrek, Terasmaa, Anton, Plaas, Mario, Vasar, Eero
Published in Scientific reports (05.07.2018)
Published in Scientific reports (05.07.2018)
Get full text
Journal Article
Treatment with the dual-incretin agonist DA-CH5 demonstrates potent therapeutic effect in a rat model of Wolfram Syndrome
Jagomäe, Toomas, Gaur, Nayana, Seppa, Kadri, Reimets, Riin, Pastak, Marko, Plaas, Mihkel, Kaasik, Allen, Vasar, Eero, Plaas, Mario
Published in Frontiers in endocrinology (Lausanne) (13.10.2023)
Published in Frontiers in endocrinology (Lausanne) (13.10.2023)
Get full text
Journal Article
A cost-effective and efficient ex vivo, ex situ human whole brain perfusion protocol for immunohistochemistry
Hade, Andreas-Christian, Philips, Mari-Anne, Promet, Liisi, Jagomäe, Toomas, Hanumantharaju, Arpana, Salumäe, Liis, Reimann, Ene, Plaas, Mario, Vasar, Eero, Väli, Marika
Published in Journal of neuroscience methods (01.04.2024)
Published in Journal of neuroscience methods (01.04.2024)
Get full text
Journal Article
Alternative Promoter Use Governs the Expression of IgLON Cell Adhesion Molecules in Histogenetic Fields of the Embryonic Mouse Brain
Jagomäe, Toomas, Singh, Katyayani, Philips, Mari-Anne, Jayaram, Mohan, Seppa, Kadri, Tekko, Triin, Gilbert, Scott F, Vasar, Eero, Lilleväli, Kersti
Published in International journal of molecular sciences (28.06.2021)
Published in International journal of molecular sciences (28.06.2021)
Get full text
Journal Article
High‐throughput proteomic analysis of chronic inflammatory skin diseases: Psoriasis and atopic dermatitis
Traks, Tanel, Reemann, Paula, Eskla, Kattri‐Liis, Ottas, Aigar, Jagomäe, Toomas, Liira, Rasmus, Ilves, Liis, Jaks, Viljar, Raam, Liisi, Abram, Kristi, Kingo, Külli
Published in Experimental dermatology (01.04.2024)
Published in Experimental dermatology (01.04.2024)
Get full text
Journal Article
VHL-deficiency leads to reductive stress in renal cells
Vellama, Hans, Eskla, Kattri-Liis, Eichelmann, Hillar, Hüva, Andria, Tennant, Daniel A., Thakker, Alpesh, Roberts, Jennie, Jagomäe, Toomas, Porosk, Rando, Laisk, Agu, Oja, Vello, Rämma, Heikko, Volke, Vallo, Vasar, Eero, Luuk, Hendrik
Published in Free radical biology & medicine (01.11.2023)
Published in Free radical biology & medicine (01.11.2023)
Get full text
Journal Article
GLP-1 receptor agonist liraglutide has a neuroprotective effect on an aged rat model of Wolfram syndrome
Seppa, Kadri, Toots, Maarja, Reimets, Riin, Jagomäe, Toomas, Koppel, Tuuliki, Pallase, Maia, Hasselholt, Stine, Krogsbæk Mikkelsen, Maiken, Randel Nyengaard, Jens, Vasar, Eero, Terasmaa, Anton, Plaas, Mario
Published in Scientific reports (31.10.2019)
Published in Scientific reports (31.10.2019)
Get full text
Journal Article
Chronic Stress Alters Hippocampal Renin-Angiotensin-Aldosterone System Component Expression in an Aged Rat Model of Wolfram Syndrome
Punapart, Marite, Reimets, Riin, Seppa, Kadri, Kirillov, Silvia, Gaur, Nayana, Eskla, Kattri-Liis, Jagomäe, Toomas, Vasar, Eero, Plaas, Mario
Published in Genes (30.03.2023)
Published in Genes (30.03.2023)
Get full text
Journal Article
Expression and impact of Lsamp neural adhesion molecule in the serotonergic neurotransmission system
Bregin, Aleksandr, Kaare, Maria, Jagomäe, Toomas, Karis, Karina, Singh, Katyayani, Laugus, Karita, Innos, Jürgen, Leidmaa, Este, Heinla, Indrek, Visnapuu, Tanel, Oja, Eva-Maria, Kõiv, Kadri, Lilleväli, Kersti, Harro, Jaanus, Philips, Mari-Anne, Vasar, Eero
Published in Pharmacology, biochemistry and behavior (01.11.2020)
Published in Pharmacology, biochemistry and behavior (01.11.2020)
Get full text
Journal Article
Neural cell adhesion molecule Negr1 deficiency in mouse results in structural brain endophenotypes and behavioral deviations related to psychiatric disorders
Singh, Katyayani, Jayaram, Mohan, Kaare, Maria, Leidmaa, Este, Jagomäe, Toomas, Heinla, Indrek, Hickey, Miriam A, Kaasik, Allen, Schäfer, Michael K, Innos, Jürgen, Lilleväli, Kersti, Philips, Mari-Anne, Vasar, Eero
Published in Scientific reports (01.04.2019)
Published in Scientific reports (01.04.2019)
Get full text
Journal Article
Wfs1- deficient rats develop primary symptoms of Wolfram syndrome: insulin-dependent diabetes, optic nerve atrophy and medullary degeneration
Plaas, Mario, Seppa, Kadri, Reimets, Riin, Jagomäe, Toomas, Toots, Maarja, Koppel, Tuuliki, Vallisoo, Tuuli, Nigul, Mait, Heinla, Indrek, Meier, Riho, Kaasik, Allen, Piirsoo, Andres, Hickey, Miriam A, Terasmaa, Anton, Vasar, Eero
Published in Scientific reports (31.08.2017)
Published in Scientific reports (31.08.2017)
Get full text
Journal Article
Hypothermia Alleviates Reductive Stress, a Root Cause of Ischemia Reperfusion Injury
Eskla, Kattri-Liis, Vellama, Hans, Tarve, Liisi, Eichelmann, Hillar, Jagomäe, Toomas, Porosk, Rando, Oja, Vello, Rämma, Heikko, Peet, Nadežda, Laisk, Agu, Volke, Vallo, Vasar, Eero, Luuk, Hendrik
Published in International journal of molecular sciences (03.09.2022)
Published in International journal of molecular sciences (03.09.2022)
Get full text
Journal Article
Early Intervention and Lifelong Treatment with GLP1 Receptor Agonist Liraglutide in a Wolfram Syndrome Rat Model with an Emphasis on Visual Neurodegeneration, Sensorineural Hearing Loss and Diabetic Phenotype
Jagomäe, Toomas, Seppa, Kadri, Reimets, Riin, Pastak, Marko, Plaas, Mihkel, Hickey, Miriam A, Kukker, Kaia Grete, Moons, Lieve, De Groef, Lies, Vasar, Eero, Kaasik, Allen, Terasmaa, Anton, Plaas, Mario
Published in Cells (Basel, Switzerland) (16.11.2021)
Published in Cells (Basel, Switzerland) (16.11.2021)
Get full text
Journal Article
The Expression of RAAS Key Receptors, Agtr2 and Bdkrb1 , Is Downregulated at an Early Stage in a Rat Model of Wolfram Syndrome
Punapart, Marite, Seppa, Kadri, Jagomäe, Toomas, Liiv, Mailis, Reimets, Riin, Kirillov, Silvia, Kaasik, Allen, Moons, Lieve, De Groef, Lies, Terasmaa, Anton, Vasar, Eero, Plaas, Mario
Published in Genes (28.10.2021)
Published in Genes (28.10.2021)
Get full text
Journal Article
Wfs1 is expressed in dopaminoceptive regions of the amniote brain and modulates levels of D1-like receptors
Tekko, Triin, Lakspere, Triin, Allikalt, Anni, End, Jaanus, Kõlvart, Karl Rene, Jagomäe, Toomas, Terasmaa, Anton, Philips, Mari-Anne, Visnapuu, Tanel, Väärtnõu, Fred, Gilbert, Scott F, Rinken, Ago, Vasar, Eero, Lilleväli, Kersti
Published in PloS one (07.03.2017)
Published in PloS one (07.03.2017)
Get full text
Journal Article
Depression-Associated Negr1 Gene-Deficiency Induces Alterations in the Monoaminergic Neurotransmission Enhancing Time-Dependent Sensitization to Amphetamine in Male Mice
Kaare, Maria, Jayaram, Mohan, Jagomäe, Toomas, Singh, Katyayani, Kilk, Kalle, Mikheim, Kaie, Leevik, Marko, Leidmaa, Este, Varul, Jane, Nõmm, Helis, Rähn, Kristi, Visnapuu, Tanel, Plaas, Mario, Lilleväli, Kersti, Schäfer, Michael K E, Philips, Mari-Anne, Vasar, Eero
Published in Brain sciences (10.12.2022)
Published in Brain sciences (10.12.2022)
Get full text
Journal Article
Chronic Alcohol Use Induces Molecular Genetic Changes in the Dorsomedial Thalamus of People with Alcohol-Related Disorders
Hade, Andreas-Christian, Philips, Mari-Anne, Reimann, Ene, Jagomäe, Toomas, Eskla, Kattri-Liis, Traks, Tanel, Prans, Ele, Kõks, Sulev, Vasar, Eero, Väli, Marika
Published in Brain sciences (29.03.2021)
Published in Brain sciences (29.03.2021)
Get full text
Journal Article
High-Fat Diet Induces Pre-Diabetes and Distinct Sex-Specific Metabolic Alterations in Negr1-Deficient Mice
Kaare, Maria, Mikheim, Kaie, Lilleväli, Kersti, Kilk, Kalle, Jagomäe, Toomas, Leidmaa, Este, Piirsalu, Maria, Porosk, Rando, Singh, Katyayani, Reimets, Riin, Taalberg, Egon, Schäfer, Michael K E, Plaas, Mario, Vasar, Eero, Philips, Mari-Anne
Published in Biomedicines (03.09.2021)
Published in Biomedicines (03.09.2021)
Get full text
Journal Article
Protease-activated CendR peptides targeting tenascin-C: mitigating off-target tissue accumulation
Tobi, Allan, Haugas, Maarja, Rabi, Kristina, Sethi, Jhalak, Põšnograjeva, Kristina, Paiste, Päärn, Jagomäe, Toomas, Pleiko, Karlis, Lingasamy, Prakash, Teesalu, Tambet
Published in Drug delivery and translational research (01.10.2024)
Published in Drug delivery and translational research (01.10.2024)
Get full text
Journal Article