High-resolution ex vivo NMR spectroscopy of human Z α1-antitrypsin
Jagger, Alistair M., Waudby, Christopher A., Irving, James A., Christodoulou, John, Lomas, David A.
Published in Nature communications (11.12.2020)
Published in Nature communications (11.12.2020)
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Journal Article
Glycans modify mesenchymal stem cell differentiation to impact on the function of resulting osteoblasts
Wilson, Katherine M, Jagger, Alistair M, Walker, Matthew, Seinkmane, Estere, Fox, James M, Kröger, Roland, Genever, Paul, Ungar, Daniel
Published in Journal of cell science (15.02.2018)
Published in Journal of cell science (15.02.2018)
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Journal Article
Scaling Concepts in Serpin Polymer Physics
Raccosta, Samuele, Librizzi, Fabio, Jagger, Alistair M, Noto, Rosina, Martorana, Vincenzo, Lomas, David A, Irving, James A, Manno, Mauro
Published in Materials (15.05.2021)
Published in Materials (15.05.2021)
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Journal Article
Inflammatory cytokine (interleukin 6 and tumour necrosis factor alpha) release in a human whole blood system in response to Streptococcus pneumoniae serotype 14 and its capsular polysaccharide
JAGGER, M. P., HUO, Z., RICHES, P. G.
Published in Clinical and experimental immunology (01.12.2002)
Published in Clinical and experimental immunology (01.12.2002)
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Journal Article
Conversion of the death inhibitor ARC to a killer activates pancreatic β cell death in diabetes
McKimpson, Wendy M., Chen, Yun, Irving, James A., Zheng, Min, Weinberger, Jeremy, Tan, Wilson Lek Wen, Tiang, Zenia, Jagger, Alistair M., Chua, Streamson C., Pessin, Jeffrey E., Foo, Roger S.-Y., Lomas, David A., Kitsis, Richard N.
Published in Developmental cell (22.03.2021)
Published in Developmental cell (22.03.2021)
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Journal Article
An antibody that prevents serpin polymerisation acts by inducing a novel allosteric behaviour
Motamedi-Shad, Neda, Jagger, Alistair M, Liedtke, Maximilian, Faull, Sarah V, Nanda, Arjun Scott, Salvadori, Enrico, Wort, Joshua L, Kay, Christopher W M, Heyer-Chauhan, Narinder, Miranda, Elena, Perez, Juan, Ordóñez, Adriana, Haq, Imran, Irving, James A, Lomas, David A
Published in Biochemical journal (01.10.2016)
Published in Biochemical journal (01.10.2016)
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Journal Article
The structural basis for Z α1-antitrypsin polymerization in the liver
Faull, Sarah V, Elliston, Emma L K, Gooptu, Bibek, Jagger, Alistair M, Aldobiyan, Ibrahim, Redzej, Adam, Badaoui, Magd, Heyer-Chauhan, Nina, Rashid, S Tamir, Reynolds, Gary M, Adams, David H, Miranda, Elena, Orlova, Elena V, Irving, James A, Lomas, David A
Published in Science advances (21.10.2020)
Published in Science advances (21.10.2020)
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Journal Article
Intrahepatic heteropolymerization of M and Z alpha-1-antitrypsin
Laffranchi, Mattia, Elliston, Emma Lk, Miranda, Elena, Perez, Juan, Ronzoni, Riccardo, Jagger, Alistair M, Heyer-Chauhan, Nina, Brantly, Mark L, Fra, Annamaria, Lomas, David A, Irving, James A
Published in JCI insight (23.07.2020)
Published in JCI insight (23.07.2020)
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Journal Article
The structural basis for Z α 1 -antitrypsin polymerization in the liver
Faull, Sarah V, Elliston, Emma L K, Gooptu, Bibek, Jagger, Alistair M, Aldobiyan, Ibrahim, Redzej, Adam, Badaoui, Magd, Heyer-Chauhan, Nina, Rashid, S Tamir, Reynolds, Gary M, Adams, David H, Miranda, Elena, Orlova, Elena V, Irving, James A, Lomas, David A
Published in Science advances (23.10.2020)
Published in Science advances (23.10.2020)
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Journal Article
The ACE (Albumin, CRP and Endoscopy) Index in Acute Colitis: A Simple Clinical Index on Admission that Predicts Outcome in Patients With Acute Ulcerative Colitis
Grant, Rebecca K, Jones, Gareth-Rhys, Plevris, Nikolas, Lynch, Ruairi W, Jenkinson, Philip W, Lees, Charlie W, Manship, Thomas A, Jagger, Fiona A M, Brindle, William M, Shivakumar, Mrithula, Satsangi, Jack, Arnott, Ian D R
Published in Inflammatory bowel diseases (01.04.2021)
Published in Inflammatory bowel diseases (01.04.2021)
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Journal Article
Development of a small molecule that corrects misfolding and increases secretion of Z α1‐antitrypsin
Lomas, David A, Irving, James A, Arico‐Muendel, Christopher, Belyanskaya, Svetlana, Brewster, Andrew, Brown, Murray, Chung, Chun‐wa, Dave, Hitesh, Denis, Alexis, Dodic, Nerina, Dossang, Anthony, Eddershaw, Peter, Klimaszewska, Diana, Haq, Imran, Holmes, Duncan S, Hutchinson, Jonathan P, Jagger, Alistair M, Jakhria, Toral, Jigorel, Emilie, Liddle, John, Lind, Ken, Marciniak, Stefan J, Messer, Jeff, Neu, Margaret, Olszewski, Allison, Ordonez, Adriana, Ronzoni, Riccardo, Rowedder, James, Rüdiger, Martin, Skinner, Steve, Smith, Kathrine J, Terry, Rebecca, Trottet, Lionel, Uings, Iain, Wilson, Steve, Zhu, Zhengrong, Pearce, Andrew C
Published in EMBO molecular medicine (05.03.2021)
Published in EMBO molecular medicine (05.03.2021)
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Journal Article
Agonist interactions with 5‐HT3 receptor recognition sites in the rat entorhinal cortex labelled by structurally diverse radioligands
Barnes, J.M., Barnes, N.M., Costall, B., Jagger, S.M., Naylor, R.J., Robertson, D.W., Roe, S.Y.
Published in British journal of pharmacology (01.02.1992)
Published in British journal of pharmacology (01.02.1992)
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Journal Article
High-resolution ex vivo NMR spectroscopy of human Z α 1 -antitrypsin
Jagger, Alistair M, Waudby, Christopher A, Irving, James A, Christodoulou, John, Lomas, David A
Published in Nature communications (11.12.2020)
Get full text
Published in Nature communications (11.12.2020)
Journal Article
Development of a small molecule that corrects misfolding and increases secretion of Z α 1 -antitrypsin
Lomas, David A, Irving, James A, Arico-Muendel, Christopher, Belyanskaya, Svetlana, Brewster, Andrew, Brown, Murray, Chung, Chun-Wa, Dave, Hitesh, Denis, Alexis, Dodic, Nerina, Dossang, Anthony, Eddershaw, Peter, Klimaszewska, Diana, Haq, Imran, Holmes, Duncan S, Hutchinson, Jonathan P, Jagger, Alistair M, Jakhria, Toral, Jigorel, Emilie, Liddle, John, Lind, Ken, Marciniak, Stefan J, Messer, Jeff, Neu, Margaret, Olszewski, Allison, Ordonez, Adriana, Ronzoni, Riccardo, Rowedder, James, Rüdiger, Martin, Skinner, Steve, Smith, Kathrine J, Terry, Rebecca, Trottet, Lionel, Uings, Iain, Wilson, Steve, Zhu, Zhengrong, Pearce, Andrew C
Published in EMBO molecular medicine (05.03.2021)
Published in EMBO molecular medicine (05.03.2021)
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Journal Article