Inducible Pluripotent Stem Cell–Derived Cardiomyocytes Reveal Aberrant Extracellular Regulated Kinase 5 and Mitogen-Activated Protein Kinase Kinase 1/2 Signaling Concomitantly Promote Hypertrophic Cardiomyopathy in RAF1-Associated Noonan Syndrome
Jaffré, Fabrice, Miller, Clint L, Schänzer, Anne, Evans, Todd, Roberts, Amy E, Hahn, Andreas, Kontaridis, Maria I
Published in Circulation (New York, N.Y.) (16.07.2019)
Published in Circulation (New York, N.Y.) (16.07.2019)
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The role of the protein tyrosine phosphatase SHP2 in cardiac development and disease
Lauriol, Jessica, Jaffré, Fabrice, Kontaridis, Maria I.
Published in Seminars in cell & developmental biology (01.01.2015)
Published in Seminars in cell & developmental biology (01.01.2015)
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Constitutively Activating GNAS Somatic Mutation in Right Ventricular Outflow Tract Tachycardia
Ip, James E., Xu, Linna, Dai, Jie, Steegborn, Clemens, Jaffré, Fabrice, Evans, Todd, Cheung, Jim W., Basson, Craig T., Panaghie, Gianina, Krogh-Madsen, Trine, Abbott, Geoffrey W., Lerman, Bruce B.
Published in Circulation. Arrhythmia and electrophysiology (01.10.2021)
Published in Circulation. Arrhythmia and electrophysiology (01.10.2021)
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Serotonin 5-HT2B Receptor Blockade Prevents Reactive Oxygen Species–Induced Cardiac Hypertrophy in Mice
Monassier, Laurent, Laplante, Marc-André, Jaffré, Fabrice, Bousquet, Pascal, Maroteaux, Luc, de Champlain, Jacques
Published in Hypertension (Dallas, Tex. 1979) (01.08.2008)
Published in Hypertension (Dallas, Tex. 1979) (01.08.2008)
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A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids
Yang, Liuliu, Han, Yuling, Nilsson-Payant, Benjamin E., Gupta, Vikas, Wang, Pengfei, Duan, Xiaohua, Tang, Xuming, Zhu, Jiajun, Zhao, Zeping, Jaffré, Fabrice, Zhang, Tuo, Kim, Tae Wan, Harschnitz, Oliver, Redmond, David, Houghton, Sean, Liu, Chengyang, Naji, Ali, Ciceri, Gabriele, Guttikonda, Sudha, Bram, Yaron, Nguyen, Duc-Huy T., Cioffi, Michele, Chandar, Vasuretha, Hoagland, Daisy A., Huang, Yaoxing, Xiang, Jenny, Wang, Hui, Lyden, David, Borczuk, Alain, Chen, Huanhuan Joyce, Studer, Lorenz, Pan, Fong Cheng, Ho, David D., tenOever, Benjamin R., Evans, Todd, Schwartz, Robert E., Chen, Shuibing
Published in Cell Stem Cell (02.07.2020)
Published in Cell Stem Cell (02.07.2020)
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Overexpression of the serotonin 5-HT2B receptor in heart leads to abnormal mitochondrial function and cardiac hypertrophy
NEBIGIL, Canan G, JAFFRE, Fabrice, MESSADDEQ, Nadia, HICKEL, Pierre, MONASSIER, Laurent, LAUNAY, Jean-Marie, MAROTEAUX, Luc
Published in Circulation (New York, N.Y.) (01.07.2003)
Published in Circulation (New York, N.Y.) (01.07.2003)
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An Immuno-Cardiac Model for Macrophage-Mediated Inflammation in COVID-19 Hearts
Yang, Liuliu, Han, Yuling, Jaffré, Fabrice, Nilsson-Payant, Benjamin E., Bram, Yaron, Wang, Pengfei, Zhu, Jiajun, Zhang, Tuo, Redmond, David, Houghton, Sean, Uhl, Skyler, Borczuk, Alain, Huang, Yaoxing, Richardson, Chanel, Chandar, Vasuretha, Acklin, Joshua A., Lim, Jean K., Chen, Zhengming, Xiang, Jenny, Ho, David D., tenOever, Benjamin R., Schwartz, Robert E., Evans, Todd, Chen, Shuibing
Published in Circulation research (25.06.2021)
Published in Circulation research (25.06.2021)
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Stimulating healthy tissue regeneration by targeting the 5-HT2B receptor in chronic liver disease
Ebrahimkhani, Mohammad R, Oakley, Fiona, Murphy, Lindsay B, Mann, Jelena, Moles, Anna, Perugorria, Maria J, Ellis, Elizabeth, Lakey, Anne F, Burt, Alastair D, Douglass, Angela, Wright, Matthew C, White, Steven A, Jaffré, Fabrice, Maroteaux, Luc, Mann, Derek A
Published in Nature Medicine (27.11.2011)
Published in Nature Medicine (27.11.2011)
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Serotonin and Angiotensin Receptors in Cardiac Fibroblasts Coregulate Adrenergic-Dependent Cardiac Hypertrophy
Jaffré, Fabrice, Bonnin, Philippe, Callebert, Jacques, Debbabi, Haythem, Setola, Vincent, Doly, Stéphane, Monassier, Laurent, Mettauer, Bertrand, Blaxall, Burns C, Launay, Jean-Marie, Maroteaux, Luc
Published in Circulation research (02.01.2009)
Published in Circulation research (02.01.2009)
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RhoA signaling in cardiomyocytes protects against stress-induced heart failure but facilitates cardiac fibrosis
Lauriol, Jessica, Keith, Kimberly, Jaffré, Fabrice, Couvillon, Anthony, Saci, Abdel, Goonasekera, Sanjeewa A, McCarthy, Jason R, Kessinger, Chase W, Wang, Jianxun, Ke, Qingen, Kang, Peter M, Molkentin, Jeffery D, Carpenter, Christopher, Kontaridis, Maria I
Published in Science signaling (21.10.2014)
Published in Science signaling (21.10.2014)
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Personalized medicine in the dish to prevent calcium leak associated with short-coupled polymorphic ventricular tachycardia in patient-derived cardiomyocytes
Sleiman, Yvonne, Reiken, Steven, Charrabi, Azzouz, Jaffré, Fabrice, Sittenfeld, Leah R, Pasquié, Jean-Luc, Colombani, Sarah, Lerman, Bruce B, Chen, Shuibing, Marks, Andrew R, Cheung, Jim W, Evans, Todd, Lacampagne, Alain, Meli, Albano C
Published in Stem cell research & therapy (23.09.2023)
Published in Stem cell research & therapy (23.09.2023)
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Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2
Yang, Liuliu, Nilsson-Payant, Benjamin E., Han, Yuling, Jaffré, Fabrice, Zhu, Jiajun, Wang, Pengfei, Zhang, Tuo, Redmond, David, Houghton, Sean, Møller, Rasmus, Hoagland, Daisy, Carrau, Lucia, Horiuchi, Shu, Goff, Marisa, Lim, Jean K., Bram, Yaron, Richardson, Chanel, Chandar, Vasuretha, Borczuk, Alain, Huang, Yaoxing, Xiang, Jenny, Ho, David D., Schwartz, Robert E., tenOever, Benjamin R., Evans, Todd, Chen, Shuibing
Published in Stem cell reports (14.09.2021)
Published in Stem cell reports (14.09.2021)
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Cyclophilin A Promotes Cardiac Hypertrophy in Apolipoprotein E–Deficient Mice
Satoh, Kimio, Nigro, Patrizia, Zeidan, Asad, Soe, Nwe Nwe, Jaffré, Fabrice, Oikawa, Masayoshi, OʼDell, Michael R, Cui, Zhaoqiang, Menon, Prashanthi, Lu, Yan, Mohan, Amy, Yan, Chen, Blaxall, Burns C, Berk, Bradford C
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2011)
Published in Arteriosclerosis, thrombosis, and vascular biology (01.05.2011)
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Generation of an induced pluripotent stem cell line (TRNDi003-A) from a Noonan syndrome with multiple lentigines (NSML) patient carrying a p.Q510P mutation in the PTPN11 gene
Li, Rong, Baskfield, Amanda, Lin, Yongshun, Beers, Jeanette, Zou, Jizhong, Liu, Chengyu, Jaffré, Fabrice, Roberts, Amy E., Ottinger, Elizabeth A., Kontaridis, Maria I., Zheng, Wei
Published in Stem cell research (01.01.2019)
Published in Stem cell research (01.01.2019)
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Modeling polymorphic ventricular tachycardia at rest using patient-specific induced pluripotent stem cell-derived cardiomyocytes
Sleiman, Yvonne, Souidi, Monia, Kumar, Ritu, Yang, Ellen, Jaffré, Fabrice, Zhou, Ting, Bernardin, Albin, Reiken, Steve, Cazorla, Olivier, Kajava, Andrey V., Moreau, Adrien, Pasquié, Jean-Luc, Marks, Andrew R., Lerman, Bruce B., Chen, Shuibing, Cheung, Jim W., Evans, Todd, Lacampagne, Alain, Meli, Albano C.
Published in EBioMedicine (01.10.2020)
Published in EBioMedicine (01.10.2020)
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Cardiomyocytes recruit monocytes upon SARS-CoV-2 infection by secreting CCL2
Yang, Liuliu, Nilsson-Payant, Benjamin E., Han, Yuling, Jaffré, Fabrice, Zhu, Jiajun, Wang, Pengfei, Zhang, Tuo, Redmond, David, Houghton, Sean, Møller, Rasmus, Hoagland, Daisy, Carrau, Lucia, Horiuchi, Shu, Goff, Marisa, Lim, Jean K., Bram, Yaron, Richardson, Chanel, Chandar, Vasuretha, Borczuk, Alain, Huang, Yaoxing, Xiang, Jenny, Ho, David D., Schwartz, Robert E., tenOever, Benjamin R., Evans, Todd, Chen, Shuibing
Published in Stem cell reports (12.10.2021)
Published in Stem cell reports (12.10.2021)
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Modeling and drug screening of inherited short-coupled polymorphic ventricular tachycardia using patient derived tissue
Sleiman, Yvonne, Reiken, Steven, Charrabi, Azzouz, Jaffré, Fabrice, Sittenfeld, Leah R., Pasquié, Jean-Luc, Lerman, Bruce B., Chen, Shuibing, Marks, Andrew R., Cheung, Jim W., Evans, Todd, Lacampagne, Alain, Meli, Albano
Published in Journal of molecular and cellular cardiology (31.12.2022)
Published in Journal of molecular and cellular cardiology (31.12.2022)
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iPSC-derived cardiomyocytes reveal aberrant ERK5 and MEK1/2 signaling concomitantly promote hypertrophic cardiomyopathy in RAF1-associated Noonan Syndrome
Jaffré, Fabrice, Miller, Clint L., Schänzer, Anne, Evans, Todd, Roberts, Amy E., Hahn, Andreas, Kontaridis, Maria I.
Published in Circulation (New York, N.Y.) (05.06.2019)
Published in Circulation (New York, N.Y.) (05.06.2019)
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