Xanthine mimetics as potent dipeptidyl peptidase IV inhibitors
Kurukulasuriya, Ravi, Rohde, Jeffrey J., Szczepankiewicz, Bruce G., Basha, Fatima, Lai, Chunqui, Jae, Hwan-Soo, Winn, Martin, Stewart, Kent D., Longenecker, Kenton L., Lubben, Thomas W., Ballaron, Stephen J., Sham, Hing L., von Geldern, Thomas W.
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Published in Bioorganic & medicinal chemistry letters (15.12.2006)
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2,4-Diarylpyrrolidine-3-carboxylic AcidsPotent ETA Selective Endothelin Receptor Antagonists. 1. Discovery of A-127722
Winn, Martin, von Geldern, Thomas W, Opgenorth, Terry J, Jae, Hwan-Soo, Tasker, Andrew S, Boyd, Steven A, Kester, Jeffrey A, Mantei, Robert A, Bal, Radhika, Sorensen, Bryan K, Wu-Wong, Jinshyun R, Chiou, William J, Dixon, Douglas B, Novosad, Eugene I, Hernandez, Lisa, Marsh, Kennan C
Published in Journal of medicinal chemistry (01.03.1996)
Published in Journal of medicinal chemistry (01.03.1996)
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Liver-Selective Glucocorticoid Antagonists: A Novel Treatment for Type 2 Diabetes
von Geldern, Thomas W, Tu, Noah, Kym, Philip R, Link, James T, Jae, Hwan-Soo, Lai, Chunqiu, Apelqvist, Theresa, Rhonnstad, Patrik, Hagberg, Lars, Koehler, Konrad, Grynfarb, Marlena, Goos-Nilsson, Annika, Sandberg, Johnny, Österlund, Marie, Barkhem, Tomas, Höglund, Marie, Wang, Jiahong, Fung, Steven, Wilcox, Denise, Nguyen, Phong, Jakob, Clarissa, Hutchins, Charles, Färnegårdh, Mathias, Kauppi, Björn, Öhman, Lars, Jacobson, Peer B
Published in Journal of medicinal chemistry (12.08.2004)
Published in Journal of medicinal chemistry (12.08.2004)
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Discovery of potent and selective inhibitors of 11β-HSD1 for the treatment of metabolic syndrome
Richards, Steven, Sorensen, Bryan, Jae, Hwan-soo, Winn, Marty, Chen, Yixian, Wang, Jiahong, Fung, Steven, Monzon, Katina, Frevert, Ernst U., Jacobson, Peer, Sham, Hing, Link, J.T.
Published in Bioorganic & medicinal chemistry letters (15.12.2006)
Published in Bioorganic & medicinal chemistry letters (15.12.2006)
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Potent and Selective Non-Benzodioxole-Containing Endothelin-A Receptor Antagonists
Tasker, Andrew S, Sorensen, Bryan K, Jae, Hwan-Soo, Winn, Martin, von Geldern, Thomas W, Dixon, Douglas B, Chiou, William J, Dayton, Brian D, Calzadila, Samuel, Hernandez, Lisa, Marsh, Kennan C, WuWong, J. Ruth, Opgenorth, Terry J
Published in Journal of medicinal chemistry (31.01.1997)
Published in Journal of medicinal chemistry (31.01.1997)
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A-204197, a new tubulin-binding agent with antimitotic activity in tumor cell lines resistant to known microtubule inhibitors
TAHIR, Stephen K, HAN, Edward K-H, NG, Shi-Chung, CREDO, Bruce, JAE, Hwan-Soo, PIETENPOL, Jennifer A, SCATENA, Caroline D, WU-WONG, Jinshyun R, FROST, David, HING SHAM, ROSENBERG, Saul H
Published in Cancer research (Chicago, Ill.) (15.07.2001)
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Published in Cancer research (Chicago, Ill.) (15.07.2001)
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Pharmacology of endothelin receptor antagonists ABT-627, ABT-546, A-182086 and A-192621: ex vivo and in vivo studies
Wessale, Jerry L, Adler, Andrew L, Novosad, Eugene I, Calzadilla, Samuel V, Dayton, Brian D, Marsh, Kennan C, Winn, Martin, Jae, Hwan-Soo, von Geldern, Thomas W, Opgenorth, Terry J, Wu-Wong, J Ruth
Published in Clinical science (1979) (01.08.2002)
Published in Clinical science (1979) (01.08.2002)
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Discovery of Novel p-Arylthio Cinnamides as Antagonists of Leukocyte Function-Associated Antigen-1/Intercellular Adhesion Molecule-1 Interaction. 4. Structure−Activity Relationship of Substituents on the Benzene Ring of the Cinnamide
Winn, Martin, Reilly, Edward B, Liu, Gang, Huth, Jeffrey R, Jae, Hwan-Soo, Freeman, Jennifer, Pei, Zhonghua, Xin, Zhili, Lynch, John, Kester, Jeff, von Geldern, Thomas W, Leitza, Sandra, DeVries, Peter, Dickinson, Robert, Mussatto, Donna, Okasinski, Gregory F
Published in Journal of medicinal chemistry (06.12.2001)
Published in Journal of medicinal chemistry (06.12.2001)
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Biaryl amide glucagon receptor antagonists
KURUKULASURIYA, Ravi, SORENSEN, Bryan K, ADLER, Andrew L, COLLINS, Christine A, LINK, James T, PATEL, Jyoti R, JAE, Hwan-Soo, WINN, Marty X, ROHDE, Jeffrey R, GRIHALDE, Nelson D, LIN, Chun W, OGIELA, Christopher A
Published in Bioorganic & medicinal chemistry letters (03.05.2004)
Published in Bioorganic & medicinal chemistry letters (03.05.2004)
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5-Membered ring heterocyclic carboxylic acids as angiotensin II antagonists
Pratt, John, Jae, Hwan-Soo, Rosenberg, Saul, Spina, Ken, Winn, Martin, Buckner, Steven, Novosad, Eugene, Kerkman, Daniel, Shiosaki, Kazumi, Opgenorth, Terry, DeBernardis, Hohn
Published in Bioorganic & medicinal chemistry letters (06.01.1994)
Published in Bioorganic & medicinal chemistry letters (06.01.1994)
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2-(Alkylamino)nicotinic acid and analogs. Potent angiotensin II antagonists
Winn, Martin, De, Biswanath, Zydowsky, Thomas M, Altenbach, Robert J, Basha, Fatima Z, Boyd, Steven A, Brune, Michael E, Buckner, Steven A, Crowell, DeAnne
Published in Journal of medicinal chemistry (03.09.1993)
Published in Journal of medicinal chemistry (03.09.1993)
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LH-RH antagonists: design and synthesis of a novel series of peptidomimetics
De, Biswanath, Plattner, Jacob J, Bush, Eugene N, Jae, Hwan Soo, Diaz, Gilbert, Johnson, Edwin S, Perun, Thomas J
Published in Journal of medicinal chemistry (01.09.1989)
Published in Journal of medicinal chemistry (01.09.1989)
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Discovery of potent and selective inhibitors of 11beta-HSD1 for the treatment of metabolic syndrome
Richards, Steven, Sorensen, Bryan, Jae, Hwan-Soo, Winn, Marty, Chen, Yixian, Wang, Jiahong, Fung, Steven, Monzon, Katina, Frevert, Ernst U, Jacobson, Peer, Sham, Hing, Link, J T
Published in Bioorganic & medicinal chemistry letters (15.12.2006)
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Published in Bioorganic & medicinal chemistry letters (15.12.2006)
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New Antimitotic Agents with Activity in Multi-Drug-Resistant Cell Lines and in Vivo Efficacy in Murine Tumor Models
Szczepankiewicz, Bruce G, Liu, Gang, Jae, Hwan-Soo, Tasker, Andrew S, Gunawardana, Indrani W, von Geldern, Thomas W, Gwaltney, Stephen L, Wu-Wong, J. Ruth, Gehrke, Laura, Chiou, William J, Credo, R. Bruce, Alder, Jeffery D, Nukkala, Michael A, Zielinski, Nicolette A, Jarvis, Ken, Mollison, Karl W, Frost, David J, Bauch, Joy L, Hui, Yu Hua, Claiborne, Akiyo K, Li, Qun, Rosenberg, Saul H
Published in Journal of medicinal chemistry (06.12.2001)
Published in Journal of medicinal chemistry (06.12.2001)
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An improved synthesis of agaritine
Wallcave, Lawrence, Nagel, Donald L, Raha, Chitta R, Jae, Hwan-Soo, Bronczyk, Susan, Kupper, Robert, Toth, Bela
Published in Journal of organic chemistry (01.10.1979)
Published in Journal of organic chemistry (01.10.1979)
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Pyrrolidine-3-carboxylic Acids as Endothelin Antagonists. 5. Highly Selective, Potent, and Orally Active ETA Antagonists
Jae, Hwan-Soo, Winn, Martin, von Geldern, Thomas W, Sorensen, Bryan K, Chiou, William J, Nguyen, Bach, Marsh, Kennan C, Opgenorth, Terry J
Published in Journal of medicinal chemistry (08.11.2001)
Published in Journal of medicinal chemistry (08.11.2001)
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Liver-Selective Glucocorticoid Antagonists: A Novel Treatment for Type 2 Diabetes
von Geldern, Thomas W, Tu, Noah, Kym, Philip R, Link, James T, Jae, Hwan-Soo, Lai, Chunqiu, Apelqvist, Theresa, Rhonnstad, Patrik, Hagberg, Lars, Koehler, Konrad, Grynfarb, Marlena, Goos-Nilsson, Annika, Sandberg, Johnny, Österlund, Marie, Barkhem, Tomas, Höglund, Marie, Wang, Jiahong, Fung, Steven, Wilcox, Denise, Nguyen, Phong, Jakob, Clarissa, Hutchins, Charles, Färnegårdh, Mathias, Kauppi, Björn, Öhman, Lars, Jacobson, Peer B
Published in Journal of medicinal chemistry (07.04.2005)
Published in Journal of medicinal chemistry (07.04.2005)
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Pyrrolidine-3-carboxylic Acids as Endothelin Antagonists. 2. Sulfonamide-Based ETA/ETB Mixed Antagonists
Jae, Hwan-Soo, Winn, Martin, Dixon, Douglas B, Marsh, Kennan C, Nguyen, Bach, Opgenorth, Terry J, von Geldern, Thomas W
Published in Journal of medicinal chemistry (26.09.1997)
Published in Journal of medicinal chemistry (26.09.1997)
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Pyrrolidine-3-carboxylic acids as endothelin antagonists. 5. Highly selective, potent, and orally active ET(A) antagonists
Jae, H S, Winn, M, von Geldern, T W, Sorensen, B K, Chiou, W J, Nguyen, B, Marsh, K C, Opgenorth, T J
Published in Journal of medicinal chemistry (08.11.2001)
Published in Journal of medicinal chemistry (08.11.2001)
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