Prime Editing Permits the Introduction of Specific Mutations in the Gene Responsible for Duchenne Muscular Dystrophy
Happi Mbakam, Cédric, Rousseau, Joël, Tremblay, Guillaume, Yameogo, Pouiré, Tremblay, Jacques P
Published in International journal of molecular sciences (31.05.2022)
Published in International journal of molecular sciences (31.05.2022)
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Journal Article
Small-molecule inhibitors of proteasome increase CjCas9 protein stability
Yaméogo, Pouiré, Majeau, Nathalie, Mbakam, Cedric Happi, Tremblay, Jacques P
Published in PloS one (19.01.2023)
Published in PloS one (19.01.2023)
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Journal Article
CRISPR-SCReT (CRISPR-Stop Codon Read Through) method to control Cas9 expression for gene editing
Yaméogo, Pouiré, Duchêne, Benjamin L., Majeau, Nathalie, Tremblay, Jacques P.
Published in Gene therapy (01.04.2022)
Published in Gene therapy (01.04.2022)
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Journal Article
Reading Frame Correction by Targeted Genome Editing Restores Dystrophin Expression in Cells From Duchenne Muscular Dystrophy Patients
Ousterout, David G, Perez-Pinera, Pablo, Thakore, Pratiksha I, Kabadi, Ami M, Brown, Matthew T, Qin, Xiaoxia, Fedrigo, Olivier, Mouly, Vincent, Tremblay, Jacques P, Gersbach, Charles A
Published in Molecular therapy (01.09.2013)
Published in Molecular therapy (01.09.2013)
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Journal Article
CRISPR-Cas9 delivery strategies with engineered extracellular vesicles
Lu, Yaoyao, Godbout, Kelly, Lamothe, Gabriel, Tremblay, Jacques P.
Published in Molecular therapy. Nucleic acids (12.12.2023)
Published in Molecular therapy. Nucleic acids (12.12.2023)
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Journal Article
Therapeutic Strategies for Dystrophin Replacement in Duchenne Muscular Dystrophy
Happi Mbakam, Cedric, Lamothe, Gabriel, Tremblay, Jacques P
Published in Frontiers in medicine (28.03.2022)
Published in Frontiers in medicine (28.03.2022)
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Journal Article
Successful Correction by Prime Editing of a Mutation in the RYR1 Gene Responsible for a Myopathy
Godbout, Kelly, Rousseau, Joël, Tremblay, Jacques P
Published in Cells (Basel, Switzerland) (22.12.2023)
Published in Cells (Basel, Switzerland) (22.12.2023)
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Journal Article
Current Status of Pharmaceutical and Genetic Therapeutic Approaches to Treat DMD
Pichavant, Christophe, Aartsma-Rus, Annemieke, Clemens, Paula R, Davies, Kay E, Dickson, George, Takeda, Shin'ichi, Wilton, Steve D, Wolff, Jon A, Wooddell, Christine I, Xiao, Xiao, Tremblay, Jacques P
Published in Molecular therapy (01.05.2011)
Published in Molecular therapy (01.05.2011)
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Journal Article
Base editing strategy for insertion of the A673T mutation in the APP gene to prevent the development of AD in vitro
Guyon, Antoine, Rousseau, Joël, Bégin, Francis-Gabriel, Bertin, Tom, Lamothe, Gabriel, Tremblay, Jacques P.
Published in Molecular therapy. Nucleic acids (04.06.2021)
Published in Molecular therapy. Nucleic acids (04.06.2021)
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Journal Article
Emerging Perspectives on Prime Editor Delivery to the Brain
BenDavid, Eli, Ramezanian, Sina, Lu, Yaoyao, Rousseau, Joël, Schroeder, Avi, Lavertu, Marc, Tremblay, Jacques P
Published in Pharmaceuticals (Basel, Switzerland) (11.06.2024)
Published in Pharmaceuticals (Basel, Switzerland) (11.06.2024)
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Nonfunctional mutant Wrn protein leads to neurological deficits, neuronal stress, microglial alteration, and immune imbalance in a mouse model of Werner syndrome
Hui, Chin Wai, St-Pierre, Marie-Kim, Detuncq, Jérôme, Aumailley, Lucie, Dubois, Marie-Julie, Couture, Vanessa, Skuk, Daniel, Marette, André, Tremblay, Jacques P., Lebel, Michel, Tremblay, Marie-Ève
Published in Brain, behavior, and immunity (01.10.2018)
Published in Brain, behavior, and immunity (01.10.2018)
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Journal Article
Increased Expression of Laminin Subunit Alpha 1 Chain by dCas9-VP160
Perrin, Arnaud, Rousseau, Joël, Tremblay, Jacques P.
Published in Molecular therapy. Nucleic acids (17.03.2017)
Published in Molecular therapy. Nucleic acids (17.03.2017)
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