Phase I and Pharmacologic Trial of Cytosine Arabinoside with the Selective Checkpoint 1 Inhibitor Sch 900776 in Refractory Acute Leukemias
KARP, Judith E, THOMAS, Brian M, MACKEY, Karen, FRESHWATER, Tomoko, LEVIS, Mark J, MCDEVITT, Michael A, CARRAWAY, Hetty E, GLADSTONE, Douglas E, SHOWEL, Margaret M, LOECHNER, Sabine, PARRY, David A, HOROWITZ, Jo Ann, GREER, Jacqueline M, ISAACS, Randi, KAUFMANN, Scott H, SORGE, Christopher, GORE, Steven D, PRATZ, Keith W, DOUGLAS SMITH, B, FLATTEN, Karen S, PETERSON, Kevin, SCHNEIDER, Paula
Published in Clinical cancer research (15.12.2012)
Published in Clinical cancer research (15.12.2012)
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Population pharmacokinetics and site of action exposures of veliparib with topotecan plus carboplatin in patients with haematological malignancies
Mehrotra, Shailly, Gopalakrishnan, Mathangi, Gobburu, Jogarao, Greer, Jacqueline M., Piekarz, Richard, Karp, Judith E., Pratz, Keith, Rudek, Michelle A.
Published in British journal of clinical pharmacology (01.08.2017)
Published in British journal of clinical pharmacology (01.08.2017)
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A phase II trial of sequential ribonucleotide reductase inhibition in aggressive myeloproliferative neoplasms
Zeidner, Joshua F, Karp, Judith E, Blackford, Amanda L, Smith, B Douglas, Gojo, Ivana, Gore, Steven D, Levis, Mark J, Carraway, Hetty E, Greer, Jacqueline M, Ivy, S Percy, Pratz, Keith W, McDevitt, Michael A
Published in Haematologica (Roma) (01.04.2014)
Published in Haematologica (Roma) (01.04.2014)
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Phase 1 and pharmacokinetic study of bolus-infusion flavopiridol followed by cytosine arabinoside and mitoxantrone for acute leukemias
Karp, Judith E., Smith, B. Douglas, Resar, Linda S., Greer, Jacqueline M., Blackford, Amanda, Zhao, Ming, Moton-Nelson, Dwella, Alino, Katrina, Levis, Mark J., Gore, Steven D., Joseph, Biju, Carraway, Hetty, McDevitt, Michael A., Bagain, Lorena, Mackey, Karen, Briel, Janet, Doyle, L. Austin, Wright, John J., Rudek, Michelle A.
Published in Blood (24.03.2011)
Published in Blood (24.03.2011)
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Population pharmacokinetics and exposure–response assessment of veliparib co-administered with temozolomide in patients with myeloid leukemias
Singh, Renu, Mehrotra, Shailly, Gopalakrishnan, Mathangi, Gojo, Ivana, Karp, Judith E., Greer, Jacqueline M., Chen, Alice, Piekarz, Richard, Kiesel, Brian F., Gobburu, Jogarao, Rudek, Michelle A., Beumer, Jan H.
Published in Cancer chemotherapy and pharmacology (01.02.2019)
Published in Cancer chemotherapy and pharmacology (01.02.2019)
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Exposure-Response Analysis of Alvocidib (Flavopiridol) Treatment by Bolus or Hybrid Administration in Newly Diagnosed or Relapsed/Refractory Acute Leukemia Patients
LaCerte, Carl, Ivaturi, Vijay, Gobburu, Joga, Greer, Jacqueline M, Doyle, L Austin, Wright, John J, Karp, Judith E, Rudek, Michelle A
Published in Clinical cancer research (15.07.2017)
Published in Clinical cancer research (15.07.2017)
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Journal Article
Randomized phase II study of two schedules of flavopiridol given as timed sequential therapy with cytosine arabinoside and mitoxantrone for adults with newly diagnosed, poor-risk acute myelogenous leukemia
KARP, Judith E, GARRETT-MAYER, Elizabeth, LEVIS, Mark J, MCDEVITT, Michael A, CARRAWAY, Hetty E, PRATZ, Keith W, GLADSTONE, Douglas E, SHOWEL, Margaret M, OTHUS, Megan, DOYLE, L. Austin, WRIGHT, John J, PAGEL, John M, ESTEY, Elihu H, RUDEK, Michelle A, DOUGLAS SMITH, B, GREER, Jacqueline M, DRYE, D. Michelle, MACKEY, Karen, SHANNON DORCY, Kathleen, GORE, Steven D
Published in Haematologica (Roma) (01.11.2012)
Published in Haematologica (Roma) (01.11.2012)
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Journal Article
Exposure-Response of Veliparib to Inform Phase II Trial Design in Refractory or Relapsed Patients with Hematological Malignancies
Mehrotra, Shailly, Gopalakrishnan, Mathangi, Gobburu, Jogarao, Ji, Jiuping, Greer, Jacqueline M, Piekarz, Richard, Karp, Judith E, Pratz, Keith W, Rudek, Michelle A
Published in Clinical cancer research (01.11.2017)
Published in Clinical cancer research (01.11.2017)
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Sorafenib Dose Recommendation in Acute Myeloid Leukemia Based on Exposure‐FLT3 Relationship
Liu, Tao, Ivaturi, Vijay, Sabato, Philip, Gobburu, Jogarao V. S., Greer, Jacqueline M., Wright, John J., Smith, B. Douglas, Pratz, Keith W., Rudek, Michelle A.
Published in Clinical and translational science (01.07.2018)
Published in Clinical and translational science (01.07.2018)
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Journal Article
Sequential Flavopiridol, Cytosine Arabinoside, and Mitoxantrone: A Phase II Trial in Adults with Poor-Risk Acute Myelogenous Leukemia
KARP, Judith E, SMITH, B. Douglas, LEVIS, Mark J, GORE, Steven D, GREER, Jacqueline, HATTENBURG, Catherine, BRIEL, Janet, JONES, Richard J, WRIGHT, John J, COLEVAS, A. Dimitri
Published in Clinical cancer research (01.08.2007)
Published in Clinical cancer research (01.08.2007)
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Journal Article
Clinical activity of sequential flavopiridol, cytosine arabinoside, and mitoxantrone for adults with newly diagnosed, poor-risk acute myelogenous leukemia
Karp, Judith E, Blackford, Amanda, Smith, B. Douglas, Alino, Katrina, Seung, Amy Hatfield, Bolaños-Meade, Javier, Greer, Jacqueline M, Carraway, Hetty E, Gore, Steven D, Jones, Richard J, Levis, Mark J, McDevitt, Michael A, Doyle, L. Austin, Wright, John J
Published in Leukemia research (01.07.2010)
Published in Leukemia research (01.07.2010)
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Journal Article
Active oral regimen for elderly adults with newly diagnosed acute myelogenous leukemia: a preclinical and phase 1 trial of the farnesyltransferase inhibitor tipifarnib (R115777, Zarnestra) combined with etoposide
Karp, Judith E., Flatten, Karen, Feldman, Eric J., Greer, Jacqueline M., Loegering, David A., Ricklis, Rebecca M., Morris, Lawrence E., Ritchie, Ellen, Smith, B. Douglas, Ironside, Valerie, Talbott, Timothy, Roboz, Gail, Le, Son B., Meng, Xue Wei, Schneider, Paula A., Dai, Nga T., Adjei, Alex A., Gore, Steven D., Levis, Mark J., Wright, John J., Garrett-Mayer, Elizabeth, Kaufmann, Scott H.
Published in Blood (14.05.2009)
Published in Blood (14.05.2009)
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Journal Article
Multi-institutional phase 2 clinical and pharmacogenomic trial of tipifarnib plus etoposide for elderly adults with newly diagnosed acute myelogenous leukemia
Karp, Judith E., Vener, Tatiana I., Raponi, Mitch, Ritchie, Ellen K., Smith, B. Douglas, Gore, Steven D., Morris, Lawrence E., Feldman, Eric J., Greer, Jacqueline M., Malek, Sami, Carraway, Hetty E., Ironside, Valerie, Galkin, Steven, Levis, Mark J., McDevitt, Michael A., Roboz, Gail R., Gocke, Christopher D., Derecho, Carlo, Palma, John, Wang, Yixin, Kaufmann, Scott H., Wright, John J., Garret-Mayer, Elizabeth
Published in Blood (05.01.2012)
Published in Blood (05.01.2012)
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Journal Article
Phase I and pharmacological study of cytarabine and tanespimycin in relapsed and refractory acute leukemia
KAUFMANN, Scott H, KARP, Judith E, MAURER, Matthew J, DOUGLAS SMITH, B, GREER, Jacqueline, YUHONG CHEN, REID, Joel M, PERCY IVY, S, AMES, Matthew M, ADJEI, Alex A, ERLICHMAN, Charles, KARNITZ, Larry M, LITZOW, Mark R, MESA, Ruben A, HOGAN, William, STEENSMA, David P, FLATTEN, Karen S, LOEGERING, David A, SCHNEIDER, Paula A, PETERSON, Kevin L
Published in Haematologica (Roma) (01.11.2011)
Published in Haematologica (Roma) (01.11.2011)
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Journal Article
Phase II Trial of Tipifarnib as Maintenance Therapy in First Complete Remission in Adults with Acute Myelogenous Leukemia and Poor-Risk Features
Karp, Judith E, Smith, B Douglas, Gojo, Ivana, Lancet, Jeffrey E, Greer, Jacqueline, Klein, Maureen, Morris, Larry, Levis, Mark J, Gore, Steven D, Wright, John J, Garrett-Mayer, Elizabeth
Published in Clinical cancer research (15.05.2008)
Published in Clinical cancer research (15.05.2008)
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Journal Article
Phase 1 dose-escalation trial of clofarabine followed by escalating dose of fractionated cyclophosphamide in adults with relapsed or refractory acute leukaemias
Zeidan, Amer M., Ricklis, Rebecca M., Carraway, Hetty E., Yun, Hyun D., Greer, Jacqueline M., Smith, B. Douglas, Levis, Mark J., McDevitt, Michael A., Pratz, Keith W., Showel, Margaret M., Gladstone, Douglas E., Gore, Steven D., Karp, Judith E.
Published in British journal of haematology (01.07.2012)
Published in British journal of haematology (01.07.2012)
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Journal Article
Phase I and Pharmacokinetic Study of Flavopiridol followed by 1-β-d-Arabinofuranosylcytosine and Mitoxantrone in Relapsed and Refractory Adult Acute Leukemias
KARP, Judith E, PASSANITI, Antonino, TIDWELL, Michael L, ROSS, Douglas D, WRIGHT, John J, COLEVAS, A. Dimitrios, BAUER, Kenneth S, GOJO, Ivana, KAUFMANN, Scott, BIBLE, Keith, GARIMELLA, Tushar S, GREER, Jacqueline, BRIEL, Janet, SMITH, B. Douglas, GORE, Steven D
Published in Clinical cancer research (01.12.2005)
Published in Clinical cancer research (01.12.2005)
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Journal Article
Targeting Vascular Endothelial Growth Factor for Relapsed and Refractory Adult Acute Myelogenous Leukemias
Karp, Judith E., Gojo, Ivana, Pili, Roberto, Gocke, Christopher D., Greer, Jacqueline, Guo, Chuanfa, Qian, David, Morris, Lawrence, Tidwell, Michael, Chen, Helen, Zwiebel, James
Published in Clinical cancer research (01.06.2004)
Published in Clinical cancer research (01.06.2004)
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Journal Article
Phase 1 and pharmacologic study of MS-275, a histone deacetylase inhibitor, in adults with refractory and relapsed acute leukemias
Gojo, Ivana, Jiemjit, Anchalee, Trepel, Jane B., Sparreboom, Alex, Figg, William D., Rollins, Sandra, Tidwell, Michael L., Greer, Jacqueline, Chung, Eun Joo, Lee, Min-Jung, Gore, Steven D., Sausville, Edward A., Zwiebel, James, Karp, Judith E.
Published in Blood (01.04.2007)
Published in Blood (01.04.2007)
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Journal Article
A phase 2 study of the farnesyltransferase inhibitor tipifarnib in poor-risk and elderly patients with previously untreated acute myelogenous leukemia
Lancet, Jeffrey E., Gojo, Ivana, Gotlib, Jason, Feldman, Eric J., Greer, Jacqueline, Liesveld, Jane L., Bruzek, Laura M., Morris, Lawrence, Park, Youn, Adjei, Alex A., Kaufmann, Scott H., Garrett-Mayer, Elizabeth, Greenberg, Peter L., Wright, John J., Karp, Judith E.
Published in Blood (15.02.2007)
Published in Blood (15.02.2007)
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