Interferon-γ-induced upregulation of immunoproteasome subunit assembly overcomes bortezomib resistance in human hematological cell lines
Niewerth, Denise, Kaspers, Gertjan J L, Assaraf, Yehuda G, van Meerloo, Johan, Kirk, Christopher J, Anderl, Janet, Blank, Jonathan L, van de Ven, Peter M, Zweegman, Sonja, Jansen, Gerrit, Cloos, Jacqueline
Published in Journal of hematology and oncology (13.01.2014)
Published in Journal of hematology and oncology (13.01.2014)
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PARP inhibition sensitizes childhood high grade glioma, medulloblastoma and ependymoma to radiation
van Vuurden, Dannis G, Hulleman, Esther, Meijer, Olga L M, Wedekind, Laurine E, Kool, Marcel, Witt, Hendrik, Vandertop, Peter W, Würdinger, Thomas, Noske, David P, Kaspers, Gertjan J L, Cloos, Jacqueline
Published in Oncotarget (01.12.2011)
Published in Oncotarget (01.12.2011)
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Genomic landscape of retinoblastoma in Rb super(-/-)p130 super(-/-) mice resembles human retinoblastoma
Kooi, Irsan E, van Mil, Saskia E, MacPherson, David, Mol, Berber M, Moll, Annette C, Meijers-Heijboer, Hanne, Kaspers, Gertjan JL, Cloos, Jacqueline, te Riele, Hein, Dorsman, Josephine C
Published in Genes chromosomes & cancer (01.03.2017)
Published in Genes chromosomes & cancer (01.03.2017)
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Effect of Noncompetitive Proteasome Inhibition on Bortezomib Resistance
Li, Xiaoming, Wood, Tabitha E., Sprangers, Remco, Jansen, Gerrit, Franke, Niels E., Mao, Xinliang, Wang, Xiaoming, Zhang, Yi, Verbrugge, Sue Ellen, Adomat, Hans, Li, Zhi Hua, Trudel, Suzanne, Chen, Christine, Religa, Tomasz L., Jamal, Nazir, Messner, Hans, Cloos, Jacqueline, Rose, David R., Navon, Ami, Guns, Emma, Batey, Robert A., Kay, Lewis E., Schimmer, Aaron D.
Published in JNCI : Journal of the National Cancer Institute (21.07.2010)
Published in JNCI : Journal of the National Cancer Institute (21.07.2010)
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Spliceosome Inhibitor Meayamycin B As a Novel Potential Chemotherapeutic Agent in ALL and AML
Wojtuszkiewicz, Anna, Assaraf, Yehuda G, Jansen, Gerrit, Koide, Kazunori, Bressin, Robert K., Basu, Upamanyu, Sonneveld, Edwin, Giovannetti, Elisa, Kaspers, Gertjan, Cloos, Jacqueline
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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MicroRNA-106b~25 cluster is upregulated in relapsed MLL-rearranged pediatric acute myeloid leukemia
Verboon, Lonneke J, Obulkasim, Askar, de Rooij, Jasmijn D E, Katsman-Kuipers, Jenny E, Sonneveld, Edwin, Baruchel, André, Trka, Jan, Reinhardt, Dirk, Pieters, Rob, Cloos, Jacqueline, Kaspers, Gertjan J L, Klusmann, Jan-Henning, Zwaan, Christian Michel, Fornerod, Maarten, van den Heuvel-Eibrink, Marry M
Published in Oncotarget (26.07.2016)
Published in Oncotarget (26.07.2016)
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Genomic landscape of retinoblastoma in Rb−/−p130−/− mice resembles human retinoblastoma
Kooi, Irsan E., van Mil, Saskia E., MacPherson, David, Mol, Berber M., Moll, Annette C., Meijers‐Heijboer, Hanne, Kaspers, Gertjan J. L., Cloos, Jacqueline, te Riele, Hein, Dorsman, Josephine C.
Published in Genes chromosomes & cancer (01.03.2017)
Published in Genes chromosomes & cancer (01.03.2017)
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Harnessing Gene Expression Profiles for the Identification of Ex Vivo Drug Response Genes in Pediatric Acute Myeloid Leukemia
Cucchi, David G J, Bachas, Costa, van den Heuvel-Eibrink, Marry M, Arentsen-Peters, Susan T C J M, Kwidama, Zinia J, Schuurhuis, Gerrit J, Assaraf, Yehuda G, de Haas, Valérie, Kaspers, Gertjan J L, Cloos, Jacqueline
Published in Cancers (15.05.2020)
Published in Cancers (15.05.2020)
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A chemical screen for medulloblastoma identifies quercetin as a putative radiosensitizer
Lagerweij, Tonny, Hiddingh, Lotte, Biesmans, Dennis, Crommentuijn, Matheus H W, Cloos, Jacqueline, Li, Xiao-Nan, Kogiso, Mari, Tannous, Bakhos A, Vandertop, W Peter, Noske, David P, Kaspers, Gertjan J L, Würdinger, Tom, Hulleman, Esther
Published in Oncotarget (14.06.2016)
Published in Oncotarget (14.06.2016)
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The Relevance of Stem Cell Load at Diagnosis for the Development of Relapse in Pediatric Acute Myeloid Leukemia
Hanekamp, Dirkje W., Denys, Barbara, Kaspers, Gertjan J.L., te Marvelde, Jeroen G., Schuurhuis, Gerrit Jan, De Haas, Valerie, De Moerloose, Barbara, de Bont, Eveline S., de Jong, Anja, Philippé, Jan, Cloos, Jacqueline, van der Velden, Vincent H.J.
Published in Blood (03.12.2015)
Published in Blood (03.12.2015)
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High VEGFC expression is associated with unique gene expression profiles and predicts adverse prognosis in pediatric and adult acute myeloid leukemia
de Jonge, Hendrik J.M., Valk, Peter J.M., Veeger, Nic J.G.M., ter Elst, Arja, den Boer, Monique L., Cloos, Jacqueline, Haas, Valérie de, van den Heuvel-Eibrink, Marry M., Kaspers, Gertjan J.L., Zwaan, Christian M., Kamps, Willem A., Löwenberg, Bob, de Bont, Eveline S.J.M.
Published in Blood (09.09.2010)
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Abstract LB-169: Ratios of immunoproteasome over constitutive proteasome expression are an indicator for sensitivity to bortezomib-containing reinduction chemotherapy in pediatric relapsed ALL and AML
Niewerth, Denise, Kaspers, Gertjan J.L., Jansen, Gerrit, Meerloo, Johan van, Zweegman, Sonja, Jenkins, Gaye, Whitlock, James A., Hunger, Stephen P., Lu, Xiaomin, Cloos, Jacqueline, Horton, Terzah M.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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Abstract 4764: Transfer of regulatory protein networks via extracellular vesicles as a candidate mechanism of apoptosis-resistance in acute myeloid leukemia
Wojtuszkiewicz, Anna, Cloos, Jacqueline, Kessler, Floortje L., Piersma, Sander, Knol, Jako, Jansen, Gerrit, Assaraf, Yehuda G., Kaspers, Gertjan L., Zweegman, Sonja, Schuurhuis, Gerrit J., Jimenez, Connie R.
Published in Cancer research (Chicago, Ill.) (01.10.2014)
Published in Cancer research (Chicago, Ill.) (01.10.2014)
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The Prognostic Impact of Cytogenetics and Karyotype Changes in Pediatric Patients with Relapsed Acute Myeloid Leukemia: A Retrospective Cohort Study within the Relapsed AML 2001/01 Study
Klein, Kim, Zimmermann, Martin, Beverloo, Berna, von Neuhoff, Christine, De Haas, Valerie, van Weelderen, Romy, Raimondi, Susana C., Cloos, Jacqueline, Abrahamsson, Jonas, Bertrand, Yves, Dworzak, Michael, Elitzur, Sarah, Fynn, Alcira, Gibson, Brenda, Ha, Shau Yin, Harrison, Christine, Hasle, Henrik, Leverger, Guy, Maschan, Alexey, Razzouk, Bassem I., Reinhardt, Dirk, Rizzari, Carmelo, Smisek, Petr, Creutzig, Ursula, Kaspers, Gertjan J.L.
Published in Blood (02.12.2016)
Published in Blood (02.12.2016)
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Conference Proceeding
Exocytosis of polyubiquitinated proteins in bortezomib-resistant leukemia cells: a role for MARCKS in acquired resistance to proteasome inhibitors
Franke, Niels E, Kaspers, Gertjan L, Assaraf, Yehuda G, van Meerloo, Johan, Niewerth, Denise, Kessler, Floortje L, Poddighe, Pino J, Kole, Jeroen, Smeets, Serge J, Ylstra, Bauke, Bi, Chonglei, Chng, Wee Joo, Horton, Terzah M, Menezes, Rene X, Musters, Renée J P, Zweegman, Sonja, Jansen, Gerrit, Cloos, Jacqueline
Published in Oncotarget (15.11.2016)
Published in Oncotarget (15.11.2016)
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Exosomes Secreted by Apoptosis-Resistant Acute Myeloid Leukemia (AML) Blasts Harbor Regulatory Network Proteins Potentially Involved in Antagonism of Apoptosis
Wojtuszkiewicz, Anna, Schuurhuis, Gerrit J., Kessler, Floortje L., Piersma, Sander R., Knol, Jaco C., Pham, Thang V., Jansen, Gerrit, Musters, René J.P., van Meerloo, Johan, Assaraf, Yehuda G., Kaspers, Gertjan J.L., Zweegman, Sonja, Cloos, Jacqueline, Jimenez, Connie R.
Published in Molecular & cellular proteomics (01.04.2016)
Published in Molecular & cellular proteomics (01.04.2016)
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Pre-B-cell leukemia homeobox interacting protein 1 is overexpressed in astrocytoma and promotes tumor cell growth and migration
van Vuurden, Dannis G, Aronica, Eleonora, Hulleman, Esther, Wedekind, Laurine E, Biesmans, Dennis, Malekzadeh, Arjan, Bugiani, Marianna, Geerts, Dirk, Noske, David P, Vandertop, W Peter, Kaspers, Gertjan J L, Cloos, Jacqueline, Würdinger, Thomas, van der Stoop, Petra P M
Published in Neuro-oncology (Charlottesville, Va.) (01.07.2014)
Published in Neuro-oncology (Charlottesville, Va.) (01.07.2014)
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High-frequency type I/II mutational shifts between diagnosis and relapse are associated with outcome in pediatric AML: implications for personalized medicine
Bachas, Costa, Schuurhuis, Gerrit Jan, Hollink, Iris H.I.M., Kwidama, Zinia J., Goemans, Bianca F., Zwaan, C. Michel, van den Heuvel-Eibrink, Marry M., de Bont, Eveline S.J.M., Reinhardt, Dirk, Creutzig, Ursula, de Haas, Valerie, Assaraf, Yehuda G., Kaspers, Gertjan J.L., Cloos, Jacqueline
Published in Blood (14.10.2010)
Published in Blood (14.10.2010)
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Abstract 1624: Methotrexate resistance in relation to treatment outcome in childhood acute lymphoblastic leukemia
Wojtuszkiewicz, Anna, Peters, Godefridus J., van Woerden, Nicole L., Dubbelman, Boas, Escherich, Gabrielle, Schmiegelow, Kjeld, Sonneveld, Edwin, Pieters, Rob, van de Ven, Peter M., Jansen, Gerrit, Assaraf, Yehuda G., Kaspers, Gertjan J L, Cloos, Jacqueline
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Clinical relevance of molecular aberrations in paediatric acute myeloid leukaemia at first relapse
Bachas, Costa, Schuurhuis, Gerrit Jan, Reinhardt, Dirk, Creutzig, Ursula, Kwidama, Zinia J., Zwaan, C. Michel, Heuvel‐Eibrink, Marry M., De Bont, Evelina S. J. M., Elitzur, Sarah, Rizzari, Carmelo, Haas, Valérie, Zimmermann, Martin, Cloos, Jacqueline, Kaspers, Gertjan J. L.
Published in British journal of haematology (01.09.2014)
Published in British journal of haematology (01.09.2014)
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