Bi- and tri-valent T cell engagers deplete tumour-associated macrophages in cancer patient samples
Scott, Eleanor M., Jacobus, Egon J., Lyons, Brian, Frost, Sally, Freedman, Joshua D., Dyer, Arthur, Khalique, Hena, Taverner, William K., Carr, Alison, Champion, Brian R., Fisher, Kerry D., Seymour, Len W., Duffy, Margaret R.
Published in Journal for immunotherapy of cancer (21.11.2019)
Published in Journal for immunotherapy of cancer (21.11.2019)
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Journal Article
Impaired β-cell glucokinase as an underlying mechanism in diet-induced diabetes
Lu, Brian, Kurmi, Kiran, Munoz-Gomez, Miguel, Jacobus Ambuludi, Egon J, Tonne, Jason M, Rakshit, Kuntol, Hitosugi, Taro, Kudva, Yogish C, Matveyenko, Aleksey V, Ikeda, Yasuhiro
Published in Disease models & mechanisms (01.06.2018)
Published in Disease models & mechanisms (01.06.2018)
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Journal Article
Reducing cell intrinsic immunity to mRNA vaccine alters adaptive immune responses in mice
Wang, Ziyin, Jacobus, Egon J., Stirling, David C., Krumm, Stefanie, Flight, Katie E., Cunliffe, Robert F., Mottl, Jonathan, Singh, Charanjit, Mosscrop, Lucy G., Santiago, Leticia Aragão, Vogel, Annette B., Kariko, Katalin, Sahin, Ugur, Erbar, Stephanie, Tregoning, John S.
Published in Molecular therapy. Nucleic acids (12.12.2023)
Published in Molecular therapy. Nucleic acids (12.12.2023)
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Journal Article
External Beam Radiation Therapy and Enadenotucirev: Inhibition of the DDR and Mechanisms of Radiation-Mediated Virus Increase
Pokrovska, Tzveta D, Jacobus, Egon J, Puliyadi, Rathi, Prevo, Remko, Frost, Sally, Dyer, Arthur, Baugh, Richard, Rodriguez-Berriguete, Gonzalo, Fisher, Kerry, Granata, Giovanna, Herbert, Katharine, Taverner, William K, Champion, Brian R, Higgins, Geoff S, Seymour, Len W, Lei-Rossmann, Janet
Published in Cancers (26.03.2020)
Published in Cancers (26.03.2020)
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Journal Article
Tumor‐Free Transplantation of Patient‐Derived Induced Pluripotent Stem Cell Progeny for Customized Islet Regeneration
El Khatib, Moustafa M., Ohmine, Seiga, Jacobus, Egon J., Tonne, Jason M., Morsy, Salma G., Holditch, Sara J., Schreiber, Claire A., Uetsuka, Koji, Fusaki, Noemi, Wigle, Dennis A., Terzic, Andre, Kudva, Yogish C., Ikeda, Yasuhiro
Published in Stem cells translational medicine (01.05.2016)
Published in Stem cells translational medicine (01.05.2016)
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Journal Article
Calcium Influx Caused by ER Stress Inducers Enhances Oncolytic Adenovirus Enadenotucirev Replication and Killing through PKCα Activation
Taverner, William K., Jacobus, Egon J., Christianson, John, Champion, Brian, Paton, Adrienne W., Paton, James C., Su, Weiheng, Cawood, Ryan, Seymour, Len W., Lei-Rossmann, Janet
Published in Molecular therapy. Oncolytics (20.12.2019)
Published in Molecular therapy. Oncolytics (20.12.2019)
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Journal Article
Expression of human CD46 and trans-complementation by murine adenovirus 1 fails to allow productive infection by a group B oncolytic adenovirus in murine cancer cells
Lei, Janet, Jacobus, Egon J, Taverner, William K, Fisher, Kerry D, Hemmi, Silvio, West, Katy, Slater, Lorna, Lilley, Fred, Brown, Alice, Champion, Brian, Duffy, Margaret R, Seymour, Len W
Published in Journal for immunotherapy of cancer (13.06.2018)
Published in Journal for immunotherapy of cancer (13.06.2018)
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Journal Article
Antagonism of Glycolysis and Reductive Carboxylation of Glutamine Potentiates Activity of Oncolytic Adenoviruses in Cancer Cells
Dyer, Arthur, Schoeps, Benjamin, Frost, Sally, Jakeman, Philip, Scott, Eleanor M, Freedman, Joshua, Jacobus, Egon J, Seymour, Leonard W
Published in Cancer research (Chicago, Ill.) (15.01.2019)
Published in Cancer research (Chicago, Ill.) (15.01.2019)
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Journal Article
Turning cold tumours hot: oncolytic virotherapy gets up close and personal with other therapeutics at the 11th Oncolytic Virus Conference
Dyer, Arthur, Baugh, Richard, Chia, Suet Lin, Frost, Sally, Iris, Jacobus, Egon J, Khalique, Hena, Pokrovska, Tzveta D, Scott, Eleanor M, Taverner, William K, Seymour, Len W, Lei, Janet
Published in Cancer gene therapy (01.03.2019)
Published in Cancer gene therapy (01.03.2019)
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Journal Article
Virally programmed extracellular vesicles sensitize cancer cells to oncolytic virus and small molecule therapy
Wedge, Marie-Eve, Jennings, Victoria A, Crupi, Mathieu J F, Poutou, Joanna, Jamieson, Taylor, Pelin, Adrian, Pugliese, Giuseppe, de Souza, Christiano Tanese, Petryk, Julia, Laight, Brian J, Boileau, Meaghan, Taha, Zaid, Alluqmani, Nouf, McKay, Hayley E, Pikor, Larissa, Khan, Sarwat Tahsin, Azad, Taha, Rezaei, Reza, Austin, Bradley, He, Xiaohong, Mansfield, David, Rose, Elaine, Brown, Emily E F, Crawford, Natalie, Alkayyal, Almohanad, Surendran, Abera, Singaravelu, Ragunath, Roy, Dominic G, Migneco, Gemma, McSweeney, Benjamin, Cottee, Mary Lynn, Jacobus, Egon J, Keller, Brian A, Yamaguchi, Takafumi N, Boutros, Paul C, Geoffrion, Michele, Rayner, Katey J, Chatterjee, Avijit, Auer, Rebecca C, Diallo, Jean-Simon, Gibbings, Derrick, tenOever, Benjamin R, Melcher, Alan, Bell, John C, Ilkow, Carolina S
Published in Nature communications (07.04.2022)
Published in Nature communications (07.04.2022)
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