Design, structure–activity relationship, and pharmacokinetic profile of pyrazole-based indoline factor Xa inhibitors
Varnes, Jeffrey G., Wacker, Dean A., Jacobson, Irina C., Quan, Mimi L., Ellis, Christopher D., Rossi, Karen A., He, Ming Y., Luettgen, Joseph M., Knabb, Robert M., Bai, Steven, He, Kan, Lam, Patrick Y.S., Wexler, Ruth R.
Published in Bioorganic & medicinal chemistry (01.12.2007)
Published in Bioorganic & medicinal chemistry (01.12.2007)
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Design, Synthesis, and Structure−Activity Relationships of Macrocyclic Hydroxamic Acids That Inhibit Tumor Necrosis Factor α Release in Vitro and in Vivo
Xue, Chu-Biao, Voss, Matthew E, Nelson, David J, Duan, James J.-W, Cherney, Robert J, Jacobson, Irina C, He, Xiaohua, Roderick, John, Chen, Lihua, Corbett, Ronald L, Wang, Li, Meyer, Dayton T, Kennedy, Kenneth, DeGrado, William F, Hardman, Karl D, Teleha, Christopher A, Jaffee, Bruce D, Liu, Rui-Qin, Copeland, Robert A, Covington, Maryanne B, Christ, David D, Trzaskos, James M, Newton, Robert C, Magolda, Ronald L, Wexler, Ruth R, Decicco, Carl P
Published in Journal of medicinal chemistry (02.08.2001)
Published in Journal of medicinal chemistry (02.08.2001)
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Synthesis and SAR of benzamidine factor Xa inhibitors containing a vicinally-substituted heterocyclic core
Fevig, John M., Pinto, Donald J., Han, Qi, Quan, Mimi L., Pruitt, James R., Jacobson, Irina C., Galemmo, Jr, Robert A., Wang, Shuaige, Orwat, Michael J., Bostrom, Lori L., Knabb, Robert M., Wong, Pancras C., Lam, Patrick Y.S., Wexler, Ruth R.
Published in Bioorganic & medicinal chemistry letters (12.03.2001)
Published in Bioorganic & medicinal chemistry letters (12.03.2001)
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Structure-activity relationships (SAR) of some tetracyclic heterocycles related to the immunosuppressive agent brequinar sodium
Pitts, William J, Jetter, James W, Pinto, Donald J, Orwat, Michael J, Batt, Douglas G, Sherk, Susan R, Petraitis, Joseph J, Jacobson, Irina C, Copeland, Robert A, Dowling, Randine L, Jaffee, Bruce D, Gardner, Tracy L, Jones, Elizabeth A, Magolda, Ronald L
Published in Bioorganic & medicinal chemistry letters (03.02.1998)
Published in Bioorganic & medicinal chemistry letters (03.02.1998)
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