Screening novel CNS drug candidates for P-glycoprotein interactions using the cell line iP-gp: In vitro efflux ratios from iP-gp and MDCK-MDR1 monolayers compared to brain distribution data from mice
Ozgür, Burak, Saaby, Lasse, Janfelt, Christian, Langthaler, Kristine, Eneberg, Elin, Jacobsen, Anne-Marie, Badolo, Lassina, Montanari, Dino, Brodin, Birger
Published in European journal of pharmaceutics and biopharmaceutics (01.12.2021)
Published in European journal of pharmaceutics and biopharmaceutics (01.12.2021)
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Journal Article
Dissipation and effects of chlortetracycline and tylosin in two agricultural soils: A field-scale study in southern Denmark
Halling-Sørensen, Bent, Jacobsen, Anne-Marie, Jensen, John, SengeløV, Gitte, Vaclavik, Elvira, Ingerslev, Flemming
Published in Environmental toxicology and chemistry (01.04.2005)
Published in Environmental toxicology and chemistry (01.04.2005)
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Journal Article
A Quantitative LC-MS/MS Method for Distinguishing the Tau Protein Forms Phosphorylated and Nonphosphorylated at Serine-396
Jacobsen, Anne-Marie, van de Merbel, Nico C., Ditlevsen, Dorte K., Tvermosegaard, Ketil, Schalk, Frank, Lambert, Wietske, Bundgaard, Christoffer, Pedersen, Jan T., Rosenqvist, Nina
Published in Journal of the American Society for Mass Spectrometry (01.03.2023)
Published in Journal of the American Society for Mass Spectrometry (01.03.2023)
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Journal Article
In vitro and in vivo characterization of Lu AA41178: A novel, brain penetrant, pan-selective Kv7 potassium channel opener with efficacy in preclinical models of epileptic seizures and psychiatric disorders
Grupe, Morten, Bentzen, Bo Hjorth, Benned-Jensen, Tau, Nielsen, Vibeke, Frederiksen, Kristen, Jensen, Henrik Sindal, Jacobsen, Anne-Marie, Skibsbye, Lasse, Sams, Anette Graven, Grunnet, Morten, Rottländer, Mario, Bastlund, Jesper Frank
Published in European journal of pharmacology (15.11.2020)
Published in European journal of pharmacology (15.11.2020)
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Journal Article
Investigating surrogate cerebrospinal fluid matrix compositions for use in quantitative LC-MS analysis of therapeutic antibodies in the cerebrospinal fluid
Fogh, Jens Rose, Jacobsen, Anne-Marie, Nguyen, Tam T. T. N., Rand, Kasper D., Olsen, Line Rørbæk
Published in Analytical and bioanalytical chemistry (01.03.2020)
Published in Analytical and bioanalytical chemistry (01.03.2020)
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Journal Article
Inhibition of P2X7 receptors by Lu AF27139 diminishes colonic hypersensitivity and CNS prostanoid levels in a rat model of visceral pain
Staal, Roland G. W., Gandhi, Adarsh, Zhou, Hua, Cajina, Manuel, Jacobsen, Anne-Marie, Hestehave, Sara, Hopper, Allen, Poda, Suresh, Chandresana, Gamini, Zorn, Stevin H., Campbell, Brian, Segerdahl, Marta, Mӧller, Thomas, Munro, Gordon
Published in Purinergic signalling (01.12.2022)
Published in Purinergic signalling (01.12.2022)
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Journal Article
Simultaneous extraction of tetracycline, macrolide and sulfonamide antibiotics from agricultural soils using pressurised liquid extraction, followed by solid-phase extraction and liquid chromatography–tandem mass spectrometry
Jacobsen, Anne Marie, Halling-Sørensen, Bent, Ingerslev, Flemming, Honoré Hansen, Steen
Published in Journal of Chromatography A (04.06.2004)
Published in Journal of Chromatography A (04.06.2004)
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Journal Article
Lack of Exposure in a First-in-Man Study Due to Aldehyde Oxidase Metabolism: Investigated by Use of super(14) C-microdose, Humanized Mice, Monkey Pharmacokinetics, and In Vitro Methods
Jensen, Klaus Gjervig, Jacobsen, Anne-Marie, Bundgaard, Christoffer, Nilausen, Dorrit Ostergaard, Thale, Zia, Chandrasena, Gamini, Jorgensen, Martin
Published in Drug metabolism and disposition (01.01.2017)
Published in Drug metabolism and disposition (01.01.2017)
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Journal Article
Lack of Exposure in a First-in-Man Study Due to Aldehyde Oxidase Metabolism: Investigated by Use of 14 C-microdose, Humanized Mice, Monkey Pharmacokinetics, and In Vitro Methods
Jensen, Klaus Gjervig, Jacobsen, Anne-Marie, Bundgaard, Christoffer, Nilausen, Dorrit Østergaard, Thale, Zia, Chandrasena, Gamini, Jørgensen, Martin
Published in Drug metabolism and disposition (01.01.2017)
Published in Drug metabolism and disposition (01.01.2017)
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Journal Article
Lack of Exposure in a First-in-Man Study Due to Aldehyde Oxidase Metabolism: Investigated by Use of 14C-microdose, Humanized Mice, Monkey Pharmacokinetics, and In Vitro Methods
Jensen, Klaus Gjervig, Jacobsen, Anne-Marie, Bundgaard, Christoffer, Nilausen, Dorrit Østergaard, Thale, Zia, Chandrasena, Gamini, Jørgensen, Martin
Published in Drug metabolism and disposition (01.01.2017)
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Published in Drug metabolism and disposition (01.01.2017)
Journal Article
Cooperation between regional authorities and industrial companies on management of the environment
Neergaard-Henrichsen, Jørgen, Knudsen, Lene Thystrup, Jessen, Jess, Jacobsen, Anne-Marie, Lambertsen, Elin, Lentz, Henriette
Published in Journal of cleaner production (1995)
Published in Journal of cleaner production (1995)
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Journal Article
Degradation and mobility of linear alkylbenzene sulfonate and nonylphenol in sludge-amended soil
Jacobsen, A.M, Mortensen, G.K, Hansen, H.C.B
Published in Journal of environmental quality (01.01.2004)
Published in Journal of environmental quality (01.01.2004)
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Journal Article