Phosphorylation of InhA inhibits mycolic acid biosynthesis and growth of Mycobacterium tuberculosis
Molle, Virginie, Gulten, Gulcin, Vilchèze, Catherine, Veyron‐Churlet, Romain, Zanella‐Cléon, Isabelle, Sacchettini, James C., Jacobs Jr, William R., Kremer, Laurent
Published in Molecular microbiology (01.12.2010)
Published in Molecular microbiology (01.12.2010)
Get full text
Journal Article
Mycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosis
Vilchèze, Catherine, Av-Gay, Yossef, Attarian, Rodgoun, Liu, Zhen, Hazbón, Manzour H, Colangeli, Roberto, Chen, Bing, Liu, Weijun, Alland, David, Sacchettini, James C, Jacobs Jr, William R
Published in Molecular microbiology (01.09.2008)
Published in Molecular microbiology (01.09.2008)
Get full text
Journal Article
Triclosan Derivatives: Towards Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis
Freundlich, Joel S., Wang, Feng, Vilchèze, Catherine, Gulten, Gulcin, Langley, Robert, Schiehser, Guy A., Jacobus, David P., Jacobs Jr, William R., Sacchettini, James C.
Published in ChemMedChem (13.02.2009)
Published in ChemMedChem (13.02.2009)
Get full text
Journal Article
The Mycobacterium tuberculosis genome at 25 years: lessons and lingering questions
Koleske, Benjamin N, Jacobs, Jr, William R, Bishai, William R
Published in The Journal of clinical investigation (01.10.2023)
Published in The Journal of clinical investigation (01.10.2023)
Get full text
Journal Article
Variation among Genome Sequences of H37Rv Strains of Mycobacterium tuberculosis from Multiple Laboratories
IOERGER, Thomas R, YICHENG FENG, SASSETTI, Chris, SACCHETTINI, James C, GANESULA, Krishna, XIAOHUA CHEN, DOBOS, Karen M, FORTUNE, Sarah, JACOBS, William R, MIZRAHI, Valerie, PARISH, Tanya, RUBIN, Eric
Published in Journal of Bacteriology (01.07.2010)
Published in Journal of Bacteriology (01.07.2010)
Get full text
Journal Article
Mycobacterial Cytochrome P450 125 (Cyp125) Catalyzes the Terminal Hydroxylation of C27 Steroids
Capyk, Jenna K., Kalscheuer, Rainer, Stewart, Gordon R., Liu, Jie, Kwon, Hyukin, Zhao, Rafael, Okamoto, Sachi, Jacobs, William R., Eltis, Lindsay D., Mohn, William W.
Published in The Journal of biological chemistry (18.12.2009)
Published in The Journal of biological chemistry (18.12.2009)
Get full text
Journal Article
Transfer of a point mutation in Mycobacterium tuberculosis inhA resolves the target of isoniazid
Jacobs, William R, Vilchèze, Catherine, Wang, Feng, Arai, Masayoshi, Hazbón, Manzour Hernando, Colangeli, Roberto, Kremer, Laurent, Weisbrod, Torin R, Alland, David, Sacchettini, James C
Published in Nature medicine (01.09.2006)
Published in Nature medicine (01.09.2006)
Get full text
Journal Article
Potential role for ESAT6 in dissemination of M. tuberculosis via human lung epithelial cells
Kinhikar, Arvind G, Verma, Indu, Chandra, Dinesh, Singh, Krishna K, Weldingh, Karin, Andersen, Peter, Hsu, Tsungda, Jacobs Jr, William R, Laal, Suman
Published in Molecular microbiology (01.01.2010)
Published in Molecular microbiology (01.01.2010)
Get full text
Journal Article
Deletion of kasB in Mycobacterium tuberculosis causes loss of acid-fastness and subclinical latent tuberculosis in immunocompetent mice
Bhatt, Apoorva, Fujiwara, Nagatoshi, Bhatt, Kiranmai, Gurcha, Sudagar S, Kremer, Laurent, Chen, Bing, Chan, John, Porcelli, Steven A, Kobayashi, Kazuo, Besra, Gurdyal S, Jacobs, William R. Jr
Published in Proceedings of the National Academy of Sciences - PNAS (20.03.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (20.03.2007)
Get full text
Journal Article
Protective T cell immunity against respiratory syncytial virus is efficiently induced by recombinant BCG
Bueno, Susan M, González, Pablo A, Cautivo, Kelly M, Mora, Jorge E, Leiva, Eduardo D, Tobar, Hugo E, Fennelly, Glenn J, Eugenin, Eliseo A, Jacobs, William R. Jr, Riedel, Claudia A, Kalergis, Alexis M
Published in Proceedings of the National Academy of Sciences - PNAS (30.12.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (30.12.2008)
Get full text
Journal Article
Exploring the mycobacteriophage metaproteome: phage genomics as an educational platform
Hatfull, Graham F, Pedulla, Marisa L, Jacobs-Sera, Deborah, Cichon, Pauline M, Foley, Amy, Ford, Michael E, Gonda, Rebecca M, Houtz, Jennifer M, Hryckowian, Andrew J, Kelchner, Vanessa A, Namburi, Swathi, Pajcini, Kostandin V, Popovich, Mark G, Schleicher, Donald T, Simanek, Brian Z, Smith, Alexis L, Zdanowicz, Gina M, Kumar, Vanaja, Peebles, Craig L, Jacobs, Jr, William R, Lawrence, Jeffrey G, Hendrix, Roger W
Published in PLoS genetics (01.06.2006)
Published in PLoS genetics (01.06.2006)
Get full text
Journal Article
Mycobacterium tuberculosis expresses methionine sulphoxide reductases A and B that protect from killing by nitrite and hypochlorite
Lee, Warren L, Gold, Benjamin, Darby, Crystal, Brot, Nathan, Jiang, Xiuju, de Carvalho, Luiz Pedro S, Wellner, Daniel, St. John, Gregory, Jacobs Jr, William R, Nathan, Carl
Published in Molecular microbiology (01.02.2009)
Published in Molecular microbiology (01.02.2009)
Get full text
Journal Article
NAD⁺ auxotrophy is bacteriocidal for the tubercle bacilli
Vilchèze, Catherine, Weinrick, Brian, Wong, Ka-Wing, Chen, Bing, Jacobs, Jr, William R
Published in Molecular microbiology (01.04.2010)
Published in Molecular microbiology (01.04.2010)
Get full text
Journal Article
Reduced virulence of an extensively drug-resistant outbreak strain of Mycobacterium tuberculosis in a murine model
Smith, Kristen L Jurcic, Saini, Divey, Bardarov, Svetoslav, Larsen, Michelle, Frothingham, Richard, Gandhi, Neel R, Jacobs, Jr, William R, Sturm, A Willem, Lee, Sunhee
Published in PloS one (01.04.2014)
Published in PloS one (01.04.2014)
Get full text
Journal Article
Protection of Mycobacterium tuberculosis from Reactive Oxygen Species Conferred by the mel2 Locus Impacts Persistence and Dissemination
Cirillo, Suat L.G, Subbian, Selvakumar, Chen, Bing, Weisbrod, Torin R, Jacobs, William R. Jr, Cirillo, Jeffrey D
Published in Infection and Immunity (01.06.2009)
Published in Infection and Immunity (01.06.2009)
Get full text
Journal Article
Mycobacterium smegmatis: The Vanguard of Mycobacterial Research
Sparks, Ian L, Derbyshire, Keith M, Jacobs, Jr, William R, Morita, Yasu S
Published in Journal of bacteriology (26.01.2023)
Published in Journal of bacteriology (26.01.2023)
Get full text
Journal Article