Polyunsaturated Fatty Acid Desaturation Is a Mechanism for Glycolytic NAD+ Recycling
Kim, Wondong, Deik, Amy, Gonzalez, Clicerio, Gonzalez, Maria Elena, Fu, Feifei, Ferrari, Michele, Churchhouse, Claire L., Florez, Jose C., Jacobs, Suzanne B.R., Clish, Clary B., Rhee, Eugene P.
Published in Cell metabolism (02.04.2019)
Published in Cell metabolism (02.04.2019)
Get full text
Journal Article
Sequence variants in SLC16A11 are a common risk factor for type 2 diabetes in Mexico
Williams, Amy L, Jacobs, Suzanne B R, Moreno-Macías, Hortensia, Huerta-Chagoya, Alicia, Churchhouse, Claire, Márquez-Luna, Carla, García-Ortíz, Humberto, Gómez-Vázquez, María José, Burtt, Noël P, Aguilar-Salinas, Carlos A, González-Villalpando, Clicerio, Florez, Jose C, Orozco, Lorena, Haiman, Christopher A, Tusié-Luna, Teresa, Altshuler, David
Published in Nature (London) (06.02.2014)
Published in Nature (London) (06.02.2014)
Get full text
Journal Article
Type 2 Diabetes Variants Disrupt Function of SLC16A11 through Two Distinct Mechanisms
Rusu, Victor, Hoch, Eitan, Mercader, Josep M., Tenen, Danielle E., Gymrek, Melissa, Hartigan, Christina R., DeRan, Michael, Guzman, Gaelen, Deik, Amy A., Pierce, Kerry A., Dennis, Courtney, Clish, Clary B., Carr, Steven A., Wagner, Bridget K., Chen, Brian H., Ng, Maggie C.Y., Chen, Brian H., Guo, Xiuqing, Liu, Jiankang, Bielinski, Suzette J., Nalls, Michael A., Rasmussen-Torvik, Laura J., Evans, Daniel S., Sun, Yan V., Patel, Sanjay R., Lu, Yingchang, Long, Jirong, Armstrong, Loren L., Yang, Lingyao, Snively, Beverly M., Palmer, Nicholette D., Mudgal, Poorva, Keene, Keith L., Freedman, Barry I., Goodarzi, Mark O., Correa, Adolfo, Sims, Mario, Couper, David, Pankow, James S., Boerwinkle, Eric, Adeyemo, Adebowale, Doumatey, Ayo, Vaidya, Dhananjay, Sedor, John R., Kabagambe, Edmond K., McKnight, Barbara, Rice, Kenneth, Bielak, Lawrence F., Gottesman, Omri, Cai, Qiuyin, Zheng, Wei, Blot, William J., Lowe, William L., Pacheco, Jennifer A., Crawford, Dana C., Rich, Stephen S., Shu, Xiao-Ou, Loos, Ruth J.F., Borecki, Ingrid B., Peyser, Patricia A., Fornage, Myriam, Evans, Michele K., Becker, Diane M., Kao, W.H. Linda, Wilson, James G., Sale, Michèle M., Liu, Simin, Rotimi, Charles N., Bowden, Donald W., Huerta-Chagoya, Alicia, Moreno-Macías, Hortensia, Manning, Alisa, Caulkins, Lizz, Burtt, Noël P., Flannick, Jason, Patterson, Nick, Tusié-Luna, Teresa, Altshuler, David, Florez, Jose C., Martínez-Hernández, Angélica, Centeno-Cruz, Federico, Zerrweck, Carlos, Contreras-Cubas, Cecilia, Córdova, Emilio, Soberón, Xavier, Orozco, Lorena, González-Villalpando, María Elena, Haiman, Christopher A., Le Marchand, Loic, Kolonel, Laurence, Rodríguez-Torres, Maribel, Segura-Kato, Yayoi, Rodríguez-Guillén, Rosario, Gómez, Donají, Alvirde, Ulices, Cortes, Maria L., Centeno-Cruz, Federico, Zerrweck, Carlos, Orozco, Lorena, Jacobs, Suzanne B.R.
Published in Cell (29.06.2017)
Published in Cell (29.06.2017)
Get full text
Journal Article
Nuclear Factor Y and Steroidogenic Factor 1 Physically and Functionally Interact to Contribute to Cell-Specific Expression of the Mouse Follicle-Stimulating Hormone-β Gene
Jacobs, Suzanne B. R, Coss, Djurdjica, McGillivray, Shauna M, Mellon, Pamela L
Published in Molecular endocrinology (Baltimore, Md.) (01.08.2003)
Published in Molecular endocrinology (Baltimore, Md.) (01.08.2003)
Get full text
Journal Article
Association of a Low-Frequency Variant in HNF1A With Type 2 Diabetes in a Latino Population
Estrada, Karol, Aukrust, Ingvild, Bjørkhaug, Lise, Burtt, Noël P, Mercader, Josep M, García-Ortiz, Humberto, Huerta-Chagoya, Alicia, Moreno-Macías, Hortensia, Walford, Geoffrey, Flannick, Jason, Williams, Amy L, Gómez-Vázquez, María J, Fernandez-Lopez, Juan C, Martínez-Hernández, Angélica, Centeno-Cruz, Federico, Mendoza-Caamal, Elvia, Revilla-Monsalve, Cristina, Islas-Andrade, Sergio, Córdova, Emilio J, Soberón, Xavier, González-Villalpando, María E, Henderson, E, Wilkens, Lynne R, Le Marchand, Loic, Arellano-Campos, Olimpia, Ordóñez-Sánchez, Maria L, Rodríguez-Torres, Maribel, Rodríguez-Guillén, Rosario, Riba, Laura, Najmi, Laeya A, Jacobs, Suzanne B.R, Fennell, Timothy, Gabriel, Stacey, Fontanillas, Pierre, Hanis, Craig L, Lehman, Donna M, Jenkinson, Christopher P, Abboud, Hanna E, Bell, Graeme I, Cortes, Maria L, Boehnke, Michael, González-Villalpando, Clicerio, Orozco, Lorena, Haiman, Christopher A, Tusié-Luna, Teresa, Aguilar-Salinas, Carlos A, Altshuler, David, Njølstad, Pål R, Florez, Jose C, MacArthur, Daniel G
Published in JAMA : the journal of the American Medical Association (11.06.2014)
Published in JAMA : the journal of the American Medical Association (11.06.2014)
Get full text
Journal Article
A Loss-of-Function Splice Acceptor Variant in IGF2 Is Protective for Type 2 Diabetes
Mercader, Josep M, Liao, Rachel G, Bell, Avery D, Dymek, Zachary, Estrada, Karol, Tukiainen, Taru, Huerta-Chagoya, Alicia, Moreno-Macías, Hortensia, Jablonski, Kathleen A, Hanson, Robert L, Walford, Geoffrey A, Moran, Ignasi, Chen, Ling, Agarwala, Vineeta, Ordoñez-Sánchez, María Luisa, Rodríguez-Guillen, Rosario, Rodríguez-Torres, Maribel, Segura-Kato, Yayoi, García-Ortiz, Humberto, Centeno-Cruz, Federico, Barajas-Olmos, Francisco, Caulkins, Lizz, Puppala, Sobha, Fontanillas, Pierre, Williams, Amy L, Bonàs-Guarch, Sílvia, Hartl, Chris, Ripke, Stephan, Tooley, Katherine, Lane, Jacqueline, Zerrweck, Carlos, Martínez-Hernández, Angélica, Córdova, Emilio J, Mendoza-Caamal, Elvia, Contreras-Cubas, Cecilia, González-Villalpando, María E, Cruz-Bautista, Ivette, Muñoz-Hernández, Liliana, Gómez-Velasco, Donaji, Alvirde, Ulises, Henderson, Brian E, Wilkens, Lynne R, Le Marchand, Loic, Arellano-Campos, Olimpia, Riba, Laura, Harden, Maegan, Gabriel, Stacey, Abboud, Hanna E, Cortes, Maria L, Revilla-Monsalve, Cristina, Islas-Andrade, Sergio, Soberon, Xavier, Curran, Joanne E, Jenkinson, Christopher P, DeFronzo, Ralph A, Lehman, Donna M, Hanis, Craig L, Bell, Graeme I, Boehnke, Michael, Blangero, John, Duggirala, Ravindranath, Saxena, Richa, MacArthur, Daniel, Ferrer, Jorge, McCarroll, Steven A, Torrents, David, Knowler, William C, Baier, Leslie J, Burtt, Noel, González-Villalpando, Clicerio, Haiman, Christopher A, Aguilar-Salinas, Carlos A, Tusié-Luna, Teresa, Flannick, Jason, Jacobs, Suzanne B R, Orozco, Lorena, Altshuler, David, Florez, Jose C
Published in Diabetes (New York, N.Y.) (01.11.2017)
Published in Diabetes (New York, N.Y.) (01.11.2017)
Get full text
Journal Article
Siva plays a critical role in mouse embryonic development
Jacobs, Suzanne B. R., Van Nostrand, Jeanine L., Bowen, Margot E., Baker, Julie C., Attardi, Laura D.
Published in Cell death and differentiation (01.01.2020)
Published in Cell death and differentiation (01.01.2020)
Get full text
Journal Article
Interaction Between Type 2 Diabetes Prevention Strategies and Genetic Determinants of Coronary Artery Disease on Cardiometabolic Risk Factors
Merino, Jordi, Jablonski, Kathleen A, Mercader, Josep M, Kahn, Steven E, Chen, Ling, Harden, Maegan, Delahanty, Linda M, Araneta, Maria Rosario G, Walford, Geoffrey A, Jacobs, Suzanne B R, Ibebuogu, Uzoma N, Franks, Paul W, Knowler, William C, Florez, Jose C
Published in Diabetes (New York, N.Y.) (01.01.2020)
Published in Diabetes (New York, N.Y.) (01.01.2020)
Get full text
Journal Article
The SLC16A11 risk haplotype is associated with decreased insulin action, higher transaminases and large-size adipocytes
Almeda-Valdes, Paloma, Gómez Velasco, Donaji V, Arellano Campos, Olimpia, Bello-Chavolla, Omar Yaxmehen, del Rocío Sevilla-González, Magdalena, Viveros Ruiz, Tannia, Martagón Rosado, Alexandro J, Bautista, Claudia J, Muñoz Hernandez, Liliana, Cruz-Bautista, Ivette, Moreno-Macias, Hortensia, Huerta-Chagoya, Alicia, Rodríguez-Álvarez, Karen Guadalupe, Walford, Geoffrey A, Jacobs, Suzanne B R, Guillen Pineda, Luz E, Ordoñez-Sánchez, Ma Luisa, Roldan-Valadez, Ernesto, Azpiroz, Joaquín, Furuzawa-Carballeda, Jannette, Clark, Patricia, Herrera-Hernández, Miguel F, Zambrano, Elena, Florez, Jose C, Tusié Luna, María Teresa, Aguilar-Salinas, Carlos A
Published in European journal of endocrinology (01.02.2019)
Published in European journal of endocrinology (01.02.2019)
Get full text
Journal Article
The p53 Target Gene SIVA Enables Non-Small Cell Lung Cancer Development
Van Nostrand, Jeanine L, Brisac, Alice, Mello, Stephano S, Jacobs, Suzanne B R, Luong, Richard, Attardi, Laura D
Published in Cancer discovery (01.06.2015)
Published in Cancer discovery (01.06.2015)
Get full text
Journal Article
The Metastasis-Associated Gene Prl-3 Is a p53 Target Involved in Cell-Cycle Regulation
Basak, Shashwati, Jacobs, Suzanne B.R., Krieg, Adam J., Pathak, Navneeta, Zeng, Qi, Kaldis, Philipp, Giaccia, Amato J., Attardi, Laura D.
Published in Molecular cell (09.05.2008)
Published in Molecular cell (09.05.2008)
Get full text
Journal Article
Discovering cellular programs of intrinsic and extrinsic drivers of metabolic traits using LipocyteProfiler
Laber, Samantha, Strobel, Sophie, Mercader, Josep M., Dashti, Hesam, dos Santos, Felipe R.C., Kubitz, Phil, Jackson, Maya, Ainbinder, Alina, Honecker, Julius, Agrawal, Saaket, Garborcauskas, Garrett, Stirling, David R., Leong, Aaron, Figueroa, Katherine, Sinnott-Armstrong, Nasa, Kost-Alimova, Maria, Deodato, Giacomo, Harney, Alycen, Way, Gregory P., Saadat, Alham, Harken, Sierra, Reibe-Pal, Saskia, Ebert, Hannah, Zhang, Yixin, Calabuig-Navarro, Virtu, McGonagle, Elizabeth, Stefek, Adam, Dupuis, Josée, Cimini, Beth A., Hauner, Hans, Udler, Miriam S., Carpenter, Anne E., Florez, Jose C., Lindgren, Cecilia, Jacobs, Suzanne B.R., Claussnitzer, Melina
Published in Cell genomics (12.07.2023)
Published in Cell genomics (12.07.2023)
Get full text
Journal Article
Analysis of Glucocorticoid-Related Genes Reveal CCHCR1 as a New Candidate Gene for Type 2 Diabetes
Brenner, Laura N, Mercader, Josep M, Robertson, Catherine C, Cole, Joanne, Chen, Ling, Jacobs, Suzanne B R, Rich, Stephen S, Florez, Jose C
Published in Journal of the Endocrine Society (01.11.2020)
Published in Journal of the Endocrine Society (01.11.2020)
Get full text
Journal Article
A Low-Frequency Inactivating AKT2 Variant Enriched in the Finnish Population Is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk
Manning, Alisa, Highland, Heather M, Gasser, Jessica, Sim, Xueling, Tukiainen, Taru, Fontanillas, Pierre, Grarup, Niels, Rivas, Manuel A, Mahajan, Anubha, Locke, Adam E, Cingolani, Pablo, Pers, Tune H, Viñuela, Ana, Brown, Andrew A, Wu, Ying, Flannick, Jason, Fuchsberger, Christian, Gamazon, Eric R, Gaulton, Kyle J, Im, Hae Kyung, Teslovich, Tanya M, Blackwell, Thomas W, Bork-Jensen, Jette, Burtt, Noël P, Chen, Yuhui, Green, Todd, Hartl, Christopher, Kang, Hyun Min, Kumar, Ashish, Ladenvall, Claes, Ma, Clement, Moutsianas, Loukas, Pearson, Richard D, Perry, John R B, Rayner, N William, Robertson, Neil R, Scott, Laura J, van de Bunt, Martijn, Eriksson, Johan G, Jula, Antti, Koskinen, Seppo, Lehtimäki, Terho, Palotie, Aarno, Raitakari, Olli T, Jacobs, Suzanne B R, Wessel, Jennifer, Chu, Audrey Y, Scott, Robert A, Goodarzi, Mark O, Blancher, Christine, Buck, Gemma, Buck, David, Chines, Peter S, Gabriel, Stacey, Gjesing, Anette P, Groves, Christopher J, Hollensted, Mette, Huyghe, Jeroen R, Jackson, Anne U, Jun, Goo, Justesen, Johanne Marie, Mangino, Massimo, Murphy, Jacquelyn, Neville, Matt, Onofrio, Robert, Small, Kerrin S, Stringham, Heather M, Trakalo, Joseph, Banks, Eric, Carey, Jason, Carneiro, Mauricio O, DePristo, Mark, Farjoun, Yossi, Fennell, Timothy, Goldstein, Jacqueline I, Grant, George, Hrabé de Angelis, Martin, Maguire, Jared, Neale, Benjamin M, Poplin, Ryan, Purcell, Shaun, Schwarzmayr, Thomas, Shakir, Khalid, Smith, Joshua D, Strom, Tim M, Wieland, Thomas, Lindstrom, Jaana, Brandslund, Ivan, Christensen, Cramer, Surdulescu, Gabriela L, Lakka, Timo A, Doney, Alex S F, Nilsson, Peter, Wareham, Nicholas J, Langenberg, Claudia, Varga, Tibor V, Franks, Paul W, Rolandsson, Olov, Rosengren, Anders H, Farook, Vidya S
Published in Diabetes (New York, N.Y.) (01.07.2017)
Published in Diabetes (New York, N.Y.) (01.07.2017)
Get full text
Journal Article