Dysregulation of kynurenine metabolism is related to proinflammatory cytokines, attention, and prefrontal cortex volume in schizophrenia
Kindler, Jochen, Lim, Chai K, Weickert, Cynthia Shannon, Boerrigter, Danny, Galletly, Cherrie, Liu, Dennis, Jacobs, Kelly R, Balzan, Ryan, Bruggemann, Jason, O'Donnell, Maryanne, Lenroot, Rhoshel, Guillemin, Gilles J, Weickert, Thomas W
Published in Molecular psychiatry (01.11.2020)
Published in Molecular psychiatry (01.11.2020)
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Journal Article
Major Developments in the Design of Inhibitors along the Kynurenine Pathway
Jacobs, Kelly R, Castellano-Gonzalez, Gloria, Guillemin, Gilles J, Lovejoy, David B
Published in Current medicinal chemistry (01.01.2017)
Published in Current medicinal chemistry (01.01.2017)
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Journal Article
Plasma neurofilament light chain and amyloid-β are associated with the kynurenine pathway metabolites in preclinical Alzheimer's disease
Chatterjee, Pratishtha, Zetterberg, Henrik, Goozee, Kathryn, Lim, Chai K, Jacobs, Kelly R, Ashton, Nicholas J, Hye, Abdul, Pedrini, Steve, Sohrabi, Hamid R, Shah, Tejal, Asih, Prita R, Dave, Preeti, Shen, Kaikai, Taddei, Kevin, Lovejoy, David B, Guillemin, Gilles J, Blennow, Kaj, Martins, Ralph N
Published in Journal of neuroinflammation (10.10.2019)
Published in Journal of neuroinflammation (10.10.2019)
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Journal Article
Systemic perturbations of the kynurenine pathway precede progression to dementia independently of amyloid-β
Cespedes, Marcela, Jacobs, Kelly R., Maruff, Paul, Rembach, Alan, Fowler, Christopher J., Trounson, Brett, Pertile, Kelly K., Rumble, Rebecca L., Rainey-Smithe, Stephanie R., Rowe, Christopher C., Villemagne, Victor L., Bourgeat, Pierrick, Lim, Chai K., Chatterjee, Pratishtha, Martins, Ralph N., Ittner, Arne, Masters, Colin L., Doecke, James D., Guillemin, Gilles J., Lovejoy, David B.
Published in Neurobiology of disease (01.09.2022)
Published in Neurobiology of disease (01.09.2022)
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Journal Article
Kynurenine 3-Monooxygenase Activity in Human Primary Neurons and Effect on Cellular Bioenergetics Identifies New Neurotoxic Mechanisms
Castellano-Gonzalez, Gloria, Jacobs, Kelly R., Don, Emily, Cole, Nicholas J., Adams, Seray, Lim, Chai K., Lovejoy, David B., Guillemin, Gilles J.
Published in Neurotoxicity research (01.04.2019)
Published in Neurotoxicity research (01.04.2019)
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Journal Article
Metabolomic Biomarkers of Multiple Sclerosis: A Systematic Review
Porter, Lachlan, Shoushtarizadeh, Alireza, Jelinek, George A, Brown, Chelsea R, Lim, Chai K, de Livera, Alysha M, Jacobs, Kelly R, Weiland, Tracey J
Published in Frontiers in molecular biosciences (14.12.2020)
Published in Frontiers in molecular biosciences (14.12.2020)
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Journal Article
Effects of Tryptophan Supplementation and Exercise on the Fate of Kynurenine Metabolites in Mice and Humans
Valente-Silva, Paula, Cervenka, Igor, Ferreira, Duarte M. S., Correia, Jorge C., Edman, Sebastian, Horwath, Oscar, Heng, Benjamin, Chow, Sharron, Jacobs, Kelly R., Guillemin, Gilles J., Blomstrand, Eva, Ruas, Jorge L.
Published in Metabolites (03.08.2021)
Published in Metabolites (03.08.2021)
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Journal Article
Correlation between plasma and CSF concentrations of kynurenine pathway metabolites in Alzheimer's disease and relationship to amyloid-β and tau
Jacobs, Kelly R., Lim, Chai K., Blennow, Kaj, Zetterberg, Henrik, Chatterjee, Pratishtha, Martins, Ralph N., Brew, Bruce J., Guillemin, Gilles J., Lovejoy, David B.
Published in Neurobiology of aging (01.08.2019)
Published in Neurobiology of aging (01.08.2019)
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Journal Article
Microbiota Alterations in Alzheimer’s Disease: Involvement of the Kynurenine Pathway and Inflammation
Garcez, Michelle L., Jacobs, Kelly R., Guillemin, Gilles J.
Published in Neurotoxicity research (01.08.2019)
Published in Neurotoxicity research (01.08.2019)
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Journal Article
Alterations in serum kynurenine pathway metabolites in individuals with high neocortical amyloid-β load: A pilot study
Chatterjee, Pratishtha, Goozee, Kathryn, Lim, Chai K, James, Ian, Shen, Kaikai, Jacobs, Kelly R, Sohrabi, Hamid R, Shah, Tejal, Asih, Prita R, Dave, Preeti, ManYan, Candice, Taddei, Kevin, Lovejoy, David B, Chung, Roger, Guillemin, Gilles J, Martins, Ralph N
Published in Scientific reports (22.05.2018)
Published in Scientific reports (22.05.2018)
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Journal Article
Riluzole does not ameliorate disease caused by cytoplasmic TDP‐43 in a mouse model of amyotrophic lateral sclerosis
Wright, Amanda L., Della Gatta, Paul A., Le, Sheng, Berning, Britt A., Mehta, Prachi, Jacobs, Kelly R., Gul, Hossai, San Gil, Rebecca, Hedl, Thomas J., Riddell, Winonah R., Watson, Owen, Keating, Sean S., Venturato, Juliana, Chung, Roger S., Atkin, Julie D., Lee, Albert, Shi, Bingyang, Blizzard, Catherine A., Morsch, Marco, Walker, Adam K.
Published in The European journal of neuroscience (01.09.2021)
Published in The European journal of neuroscience (01.09.2021)
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Journal Article
Plasma neurofilament light chain and amyloid-[beta] are associated with the kynurenine pathway metabolites in preclinical Alzheimer's disease
Chatterjee, Pratishtha, Zetterberg, Henrik, Goozee, Kathryn, Lim, Chai K, Jacobs, Kelly R, Ashton, Nicholas J, Hye, Abdul, Pedrini, Steve, Sohrabi, Hamid R, Shah, Tejal, Asih, Prita R, Dave, Preeti, Shen, Kaikai, Taddei, Kevin, Lovejoy, David B, Guillemin, Gilles J, Blennow, Kaj, Ma
Published in Journal of neuroinflammation (10.10.2019)
Published in Journal of neuroinflammation (10.10.2019)
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Journal Article
Riluzole does not ameliorate disease caused by cytoplasmic TDP-43 in a mouse model of amyotrophic lateral sclerosis
Wright, Amanda L, Paul Della Gatta, Le, Sheng, Berning, Britt A, Mehta, Prachi, Jacobs, Kelly R, Hossai Gul, Rebecca San Gil, Hedl, Thomas J, Riddell, Winonah R, Watson, Owen, Keating, Sean S, Venturato, Juliana, Chung, Roger S, Atkin, Julie D, Lee, Albert, Shi, Bingyang, Blizzard, Catherine A, Morsch, Marco, Walker, Adam K
Published in bioRxiv (10.06.2020)
Published in bioRxiv (10.06.2020)
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