Structure and folding of a designed knotted protein
King, Neil P., Jacobitz, Alex W., Sawaya, Michael R., Goldschmidt, Lukasz, Yeates, Todd O., Baker, David
Published in Proceedings of the National Academy of Sciences - PNAS (30.11.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (30.11.2010)
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Utility of physiologically based pharmacokinetic modeling to predict inter-antibody variability in monoclonal antibody pharmacokinetics in mice
Liu, Shufang, Humphreys, Sara C., Cook, Kevin D., Conner, Kip P., Correia, Ana R., Jacobitz, Alex W., Yang, Melissa, Primack, Ronya, Soto, Marcus, Padaki, Rupa, Lubomirski, Mariusz, Smith, Richard, Mock, Marissa, Thomas, Veena A.
Published in mAbs (31.12.2023)
Published in mAbs (31.12.2023)
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Structural and Computational Studies of the Staphylococcus aureus Sortase B-Substrate Complex Reveal a Substrate-stabilized Oxyanion Hole
Jacobitz, Alex W., Wereszczynski, Jeff, Yi, Sung Wook, Amer, Brendan R., Huang, Grace L., Nguyen, Angelyn V., Sawaya, Michael R., Jung, Michael E., McCammon, J.Andrew, Clubb, Robert T.
Published in The Journal of biological chemistry (28.03.2014)
Published in The Journal of biological chemistry (28.03.2014)
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Tryptophan Oxidation of a Monoclonal Antibody Under Diverse Oxidative Stress Conditions: Distinct Oxidative Pathways Favor Specific Tryptophan Residues
Jacobitz, Alex W., Liu, Qian, Suravajjala, Sreekanth, Agrawal, Neeraj J.
Published in Journal of pharmaceutical sciences (01.02.2021)
Published in Journal of pharmaceutical sciences (01.02.2021)
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The “Lid” in the Streptococcus pneumoniae SrtC1 Sortase Adopts a Rigid Structure that Regulates Substrate Access to the Active Site
Jacobitz, Alex W, Naziga, Emmanuel B, Yi, Sung Wook, McConnell, Scott A, Peterson, Robert, Jung, Michael E, Clubb, Robert T, Wereszczynski, Jeff
Published in The journal of physical chemistry. B (25.08.2016)
Published in The journal of physical chemistry. B (25.08.2016)
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Development of in silico models to predict viscosity and mouse clearance using a comprehensive analytical data set collected on 83 scaffold-consistent monoclonal antibodies
Mock, Marissa, Jacobitz, Alex W., Langmead, Christopher James, Sudom, Athena, Yoo, Daniel, Humphreys, Sara C., Alday, Mai, Alekseychyk, Larysa, Angell, Nicolas, Bi, Vivian, Catterall, Hannah, Chen, Chen-Chun, Chou, Hui-Ting, Conner, Kip P., Cook, Kevin D., Correia, Ana R., Dykstra, Andrew, Ghimire-Rijal, Sudipa, Graham, Kevin, Grandsard, Peter, Huh, Joon, Hui, John O., Jain, Mani, Jann, Victoria, Jia, Lei, Johnstone, Sheree, Khanal, Neelam, Kolvenbach, Carl, Narhi, Linda, Padaki, Rupa, Pelegri-O’Day, Emma M., Qi, Wei, Razinkov, Vladimir, Rice, Austin J., Smith, Richard, Spahr, Christopher, Stevens, Jennitte, Sun, Yax, Thomas, Veena A., van Driesche, Sarah, Vernon, Robert, Wagner, Victoria, Walker, Kenneth W., Wei, Yangjie, Winters, Dwight, Yang, Melissa, Campuzano, Iain D. G.
Published in mAbs (31.12.2023)
Published in mAbs (31.12.2023)
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Structural and Computational Studies of the Staphylococcus Aureus Sortase B-Substrate Complex Provide New Insight into the Mechanism of Sortase Transpeptidases
Jacobitz, Alex W., Wereszczynski, Jeff, Yi, Sung Wook, Amer, Brendan R., Huang, Grace L., Nguyen, Angelyn V., Sawaya, Michael R., Jung, Michael E., McCammon, J Andrew, Clubb, Robert T.
Published in Biophysical journal (28.01.2014)
Published in Biophysical journal (28.01.2014)
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Journal Article
Utility of physiologically based pharmacokinetic modeling to predict inter-antibody variability in monoclonal antibody pharmacokinetics in mice
Liu, Shufang, Humphreys, Sara C., Cook, Kevin D., Conner, Kip P., Correia, Ana R., Jacobitz, Alex W., Yang, Melissa, Primack, Ronya, Soto, Marcus, Padaki, Rupa, Lubomirski, Mariusz, Smith, Richard, Mock, Marissa, Thomas, Veena A.
Published in mAbs (31.12.2023)
Published in mAbs (31.12.2023)
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ANTICORPS BISPÉCIFIQUES AYANT DES ÉTIQUETTES APPAIRÉES À DES CHARGES C-TERMINALES CLIVABLES
GRAHAM, Kevin, ROMANINI, Dante, AGRAWAL, Neeraj J, WAGNER, Victoria, THIEL, Oliver, JACOBITZ, Alex W, LOW, Ray Lieh Yoon, MOHR, Christopher, KAWOOYA, John K, SMITH, Stephen
Year of Publication 17.03.2021
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Year of Publication 17.03.2021
Patent
Development of in silico models to predict viscosity and mouse clearance using a comprehensive analytical data set collected on 83 scaffold-consistent monoclonal antibodies
Mock, Marissa, Jacobitz, Alex W., Langmead, Christopher James, Sudom, Athena, Yoo, Daniel, Humphreys, Sara C., Alday, Mai, Alekseychyk, Larysa, Angell, Nicolas, Bi, Vivian, Catterall, Hannah, Chen, Chen-Chun, Chou, Hui-Ting, Conner, Kip P., Cook, Kevin D., Correia, Ana R., Dykstra, Andrew, Ghimire-Rijal, Sudipa, Graham, Kevin, Grandsard, Peter, Huh, Joon, Hui, John O., Jain, Mani, Jann, Victoria, Jia, Lei, Johnstone, Sheree, Khanal, Neelam, Kolvenbach, Carl, Narhi, Linda, Padaki, Rupa, Pelegri-O'Day, Emma M., Qi, Wei, Razinkov, Vladimir, Rice, Austin J., Smith, Richard, Spahr, Christopher, Stevens, Jennitte, Sun, Yax, Thomas, Veena A., van Driesche, Sarah, Vernon, Robert, Wagner, Victoria, Walker, Kenneth W., Wei, Yangjie, Winters, Dwight, Yang, Melissa, Campuzano, Iain D. G.
Published in mAbs (31.12.2023)
Published in mAbs (31.12.2023)
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Structure and folding of a designed knotted protein
King, Neil P, Jacobitz, Alex W, Sawaya, Michael R, Goldschmidt, Lukasz, Yeates, Todd O
Year of Publication 2015
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Year of Publication 2015
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