Haploinsufficiency of NADPH Oxidase Subunit Neutrophil Cytosolic Factor 2 Is Sufficient to Accelerate Full‐Blown Lupus in NZM 2328 Mice
Jacob, Chaim O., Yu, Ning, Yoo, Dae‐Goon, Perez‐Zapata, Lizet J., Barbu, Emilia Alina, Kaplan, Mariana J., Purmalek, Monica, Pingel, Jeanette T., Idol, Rachel A., Dinauer, Mary C.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.08.2017)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.08.2017)
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Identification of a Systemic Lupus Erythematosus Risk Locus Spanning ATG16L2, FCHSD2, and P2RY2 in Koreans
Lessard, Christopher J., Sajuthi, Satria, Zhao, Jian, Kim, Kwangwoo, Ice, John A., Li, He, Ainsworth, Hannah, Rasmussen, Astrid, Kelly, Jennifer A., Marion, Miranda, Bang, So‐Young, Bin Joo, Young, Choi, Jeongim, Lee, Hye‐Soon, Mo Kang, Young, Suh, Chang‐Hee, Tae Chung, Won, Lee, Soo‐Kon, Choe, Jung‐Yoon, Cheol Shim, Seung, Hee Oh, Ji, Jin Kim, Young, Han, Bok‐Ghee, Shen, Nan, Siew Howe, Hwee, Wakeland, Edward K., Li, Quan‐Zhen, Wook Song, Yeong, Gaffney, Patrick M., Alarcón‐Riquelme, Marta E., Criswell, Lindsey A., Jacob, Chaim O., Kimberly, Robert P., Vyse, Timothy J., Harley, John B., Sivils, Kathy L., Bae, Sang‐Cheol, Langefeld, Carl D., Tsao, Betty P.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2016)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.05.2016)
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Lupus-associated causal mutation in neutrophil cytosolic factor 2 (NCF2) brings unique insights to the structure and function of NADPH oxidase
Jacob, Chaim O, Eisenstein, Miriam, Dinauer, Mary C, Ming, Wenyu, Liu, Qiang, John, Sutha, Quismorio, Francesco P., Jr, Reiff, Andreas, Myones, Barry L, Kaufman, Kenneth M, McCurdy, Deborah, Harley, John B, Silverman, Earl, Kimberly, Robert P, Vyse, Timothy J, Gaffney, Patrick M, Moser, Kathy L, Klein-Gitelman, Marisa, Wagner-Weiner, Linda, Langefeld, Carl D, Armstrong, Don L, Zidovetzki, Raphael
Published in Proceedings of the National Academy of Sciences - PNAS (10.01.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (10.01.2012)
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Journal Article
Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans
Hanscombe, Ken B, Morris, David L, Noble, Janelle A, Dilthey, Alexander T, Tombleson, Philip, Kaufman, Kenneth M, Comeau, Mary, Langefeld, Carl D, Alarcon-Riquelme, Marta E, Gaffney, Patrick M, Jacob, Chaim O, Sivils, Kathy L, Tsao, Betty P, Alarcon, Graciela S, Brown, Elizabeth E, Croker, Jennifer, Edberg, Jeff, Gilkeson, Gary, James, Judith A, Kamen, Diane L, Kelly, Jennifer A, McCune, Joseph, Merrill, Joan T, Petri, Michelle, Ramsey-Goldman, Rosalind, Reveille, John D, Salmon, Jane E, Scofield, Hal, Utset, Tammy, Wallace, Daniel J, Weisman, Michael H, Kimberly, Robert P, Harley, John B, Lewis, Cathryn M, Criswell, Lindsey A, Vyse, Timothy J
Published in Human molecular genetics (01.11.2018)
Published in Human molecular genetics (01.11.2018)
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Journal Article
IgG1 protects against renal disease in a mouse model of cryoglobulinaemia
Strait, Richard T, Posgai, Monica T, Mahler, Ashley, Barasa, Nathaniel, Jacob, Chaim O, Köhl, Jörg, Ehlers, Marc, Stringer, Keith, Shanmukhappa, Shiva Kumar, Witte, David, Hossain, Md Monir, Khodoun, Marat, Herr, Andrew B, Finkelman, Fred D
Published in Nature (London) (22.01.2015)
Published in Nature (London) (22.01.2015)
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Deficiency of Type I IFN Receptor in Lupus-Prone New Zealand Mixed 2328 Mice Decreases Dendritic Cell Numbers and Activation and Protects from Disease
Agrawal, Hemant, Jacob, Noam, Carreras, Esther, Bajana, Sandra, Putterman, Chaim, Turner, Sean, Neas, Barbara, Mathian, Alexis, Koss, Michael N, Stohl, William, Kovats, Susan, Jacob, Chaim O
Published in The Journal of immunology (1950) (01.11.2009)
Published in The Journal of immunology (1950) (01.11.2009)
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Risk alleles for systemic lupus erythematosus in a large case-control collection and associations with clinical subphenotypes
Taylor, Kimberly E, Chung, Sharon A, Graham, Robert R, Ortmann, Ward A, Lee, Annette T, Langefeld, Carl D, Jacob, Chaim O, Kamboh, M Ilyas, Alarcón-Riquelme, Marta E, Tsao, Betty P, Moser, Kathy L, Gaffney, Patrick M, Harley, John B, Petri, Michelle, Manzi, Susan, Gregersen, Peter K, Behrens, Timothy W, Criswell, Lindsey A
Published in PLoS genetics (01.02.2011)
Published in PLoS genetics (01.02.2011)
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Accelerated Pathological and Clinical Nephritis in Systemic Lupus Erythematosus-Prone New Zealand Mixed 2328 Mice Doubly Deficient in TNF Receptor 1 and TNF Receptor 2 via a Th17-Associated Pathway
Jacob, Noam, Yang, Haitao, Pricop, Luminita, Liu, Yi, Gao, Xiaoni, Zheng, Song Guo, Wang, Juhua, Gao, Hua-Xin, Putterman, Chaim, Koss, Michael N, Stohl, William, Jacob, Chaim O
Published in The Journal of immunology (1950) (15.02.2009)
Published in The Journal of immunology (1950) (15.02.2009)
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Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus
Sanchez, Elena, Nadig, Ajay, Richardson, Bruce C, Freedman, Barry I, Kaufman, Kenneth M, Kelly, Jennifer A, Niewold, Timothy B, Kamen, Diane L, Gilkeson, Gary S, Ziegler, Julie T, Langefeld, Carl D, Alarcón, Graciela S, Edberg, Jeffrey C, Ramsey-Goldman, Rosalind, Petri, Michelle, Brown, Elizabeth E, Kimberly, Robert P, Reveille, John D, Vilá, Luis M, Merrill, Joan T, Anaya, Juan-Manuel, James, Judith A, Pons-Estel, Bernardo A, Martin, Javier, Park, So-Yeon, Bang, So-Young, Bae, Sang-Cheol, Moser, Kathy L, Vyse, Timothy J, Criswell, Lindsey A, Gaffney, Patrick M, Tsao, Betty P, Jacob, Chaim O, Harley, John B, Alarcón-Riquelme, Marta E, Sawalha, Amr H
Published in Annals of the rheumatic diseases (01.10.2011)
Published in Annals of the rheumatic diseases (01.10.2011)
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Journal Article
Differential Development of Systemic Lupus Erythematosus in NZM 2328 Mice Deficient in Discrete Pairs of BAFF Receptors
Jacob, Chaim O., Yu, Ning, Sindhava, Vishal, Cancro, Michael P., Pawar, Rahul D., Putterman, Chaim, Stohl, William
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.09.2015)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.09.2015)
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Essential role and therapeutic targeting of the glomerular endothelial glycocalyx in lupus nephritis
Kadoya, Hiroyuki, Yu, Ning, Schiessl, Ina Maria, Riquier-Brison, Anne, Gyarmati, Georgina, Desposito, Dorinne, Kidokoro, Kengo, Butler, Matthew J, Jacob, Chaim O, Peti-Peterdi, János
Published in JCI insight (02.10.2020)
Published in JCI insight (02.10.2020)
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Journal Article
Development of Systemic Lupus Erythematosus in NZM 2328 Mice in the Absence of any Single BAFF Receptor
Jacob, Chaim O., Yu, Ning, Guo, Shunhua, Jacob, Noam, Quinn, William J., Sindhava, Vishal, Cancro, Michael P., Goilav, Beatrice, Putterman, Chaim, Migone, Thi‐Sau, Stohl, William
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.04.2013)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.04.2013)
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Inhibition of B cell activation following in vivo co-engagement of B cell antigen receptor and Fcγ receptor IIb in non-autoimmune-prone and SLE-prone mice
Chu, Seung Y., Pong, Erik, Bonzon, Christine, Yu, Ning, Jacob, Chaim O., Chalmers, Samantha A., Putterman, Chaim, Szymkowski, David E., Stohl, William
Published in Journal of translational autoimmunity (Online) (01.01.2021)
Published in Journal of translational autoimmunity (Online) (01.01.2021)
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Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4
Manku, Harinder, Langefeld, Carl D, Guerra, Sandra G, Malik, Talat H, Alarcon-Riquelme, Marta, Anaya, Juan-Manuel, Bae, Sang-Cheol, Boackle, Susan A, Brown, Elizabeth E, Criswell, Lindsey A, Freedman, Barry I, Gaffney, Patrick M, Gregersen, Peter A, Guthridge, Joel M, Han, Sang-Hoon, Harley, John B, Jacob, Chaim O, James, Judith A, Kamen, Diane L, Kaufman, Kenneth M, Kelly, Jennifer A, Martin, Javier, Merrill, Joan T, Moser, Kathy L, Niewold, Timothy B, Park, So-Yeon, Pons-Estel, Bernardo A, Sawalha, Amr H, Scofield, R Hal, Shen, Nan, Stevens, Anne M, Sun, Celi, Gilkeson, Gary S, Edberg, Jeff C, Kimberly, Robert P, Nath, Swapan K, Tsao, Betty P, Vyse, Tim J
Published in PLoS genetics (01.07.2013)
Published in PLoS genetics (01.07.2013)
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Nomenclature of Toso, Fas apoptosis inhibitory molecule 3, and IgM FcR
Kubagawa, Hiromi, Carroll, Michael C, Jacob, Chaim O, Lang, Karl S, Lee, Kyeong-Hee, Mak, Tak, McAndrews, Monica, Morse, 3rd, Herbert C, Nolan, Garry P, Ohno, Hiroshi, Richter, Günther H, Seal, Ruth, Wang, Ji-Yang, Wiestner, Adrian, Coligan, John E
Published in The Journal of immunology (1950) (01.05.2015)
Published in The Journal of immunology (1950) (01.05.2015)
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Journal Article
Paucity of Clinical Disease despite Serological Autoimmunity and Kidney Pathology in Lupus-Prone New Zealand Mixed 2328 Mice Deficient in BAFF
Jacob, Chaim O, Pricop, Luminita, Putterman, Chaim, Koss, Michael N, Liu, Yi, Kollaros, Maria, Bixler, Sarah A, Ambrose, Christine M, Scott, Martin L, Stohl, William
Published in Journal of Immunology (15.08.2006)
Published in Journal of Immunology (15.08.2006)
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Journal Article
Evidence for gene-gene epistatic interactions among susceptibility loci for systemic lupus erythematosus
Hughes, Travis, Adler, Adam, Kelly, Jennifer A., Kaufman, Kenneth M., Williams, Adrienne H., Langefeld, Carl D., Brown, Elizabeth E., Alarcón, Graciela S., Kimberly, Robert P., Edberg, Jeffrey C., Ramsey-Goldman, Rosalind, Petri, Michelle, Boackle, Susan A., Stevens, Anne M., Reveille, John D., Sanchez, Elena, Martín, Javier, Niewold, Timothy B., Vilá, Luis M., Scofield, R. Hal, Gilkeson, Gary S., Gaffney, Patrick M., Criswell, Lindsey A., Moser, Kathy L., Merrill, Joan T., Jacob, Chaim O., Tsao, Betty P., James, Judith A., Vyse, Timothy J., Alarcón-Riquelme, Marta E., Harley, John B., Richardson, Bruce C., Sawalha, Amr H.
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.02.2012)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.02.2012)
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