A Critical Role for LTA₄H in Limiting Chronic Pulmonary Neutrophilic Inflammation
Snelgrove, Robert J., Jackson, Patricia L., Hardison, Matthew T., Noerager, Brett D., Kinloch, Andrew, Gaggar, Amit, Shastry, Suresh, Rowe, Steven M., Shim, Yun M., Hussell, Tracy, Blalock, J. Edwin
Published in Science (American Association for the Advancement of Science) (01.10.2010)
Published in Science (American Association for the Advancement of Science) (01.10.2010)
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Vaporized E-Cigarette Liquids Induce Ion Transport Dysfunction in Airway Epithelia
Lin, Vivian Y, Fain, Matthew D, Jackson, Patricia L, Berryhill, Taylor F, Wilson, Landon S, Mazur, Marina, Barnes, Stephen J, Blalock, J Edwin, Raju, S Vamsee, Rowe, Steven M
Published in American journal of respiratory cell and molecular biology (01.08.2019)
Published in American journal of respiratory cell and molecular biology (01.08.2019)
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Collagen degradation and neutrophilic infiltration: a vicious circle in inflammatory bowel disease
Koelink, Pim J, Overbeek, Saskia A, Braber, Saskia, Morgan, Mary E, Henricks, Paul A J, Roda, Mojtaba Abdul, Verspaget, Hein W, Wolfkamp, Simone C, te Velde, Anje A, Jones, Caleb W, Jackson, Patricia L, Blalock, J Edwin, Sparidans, Rolf W, Kruijtzer, John A W, Garssen, Johan, Folkerts, Gert, Kraneveld, Aletta D
Published in Gut (01.04.2014)
Published in Gut (01.04.2014)
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N-alpha-PGP and PGP, potential biomarkers and therapeutic targets for COPD
O'Reilly, Philip, Jackson, Patricia L, Noerager, Brett, Parker, Suzanne, Dransfield, Mark, Gaggar, Amit, Blalock, J Edwin
Published in Respiratory research (18.05.2009)
Published in Respiratory research (18.05.2009)
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The Cystic Fibrosis Transmembrane Conductance Regulator Potentiator Ivacaftor Augments Mucociliary Clearance Abrogating Cystic Fibrosis Transmembrane Conductance Regulator Inhibition by Cigarette Smoke
Raju, S Vamsee, Lin, Vivian Y, Liu, Limbo, McNicholas, Carmel M, Karki, Suman, Sloane, Peter A, Tang, Liping, Jackson, Patricia L, Wang, Wei, Wilson, Landon, Macon, Kevin J, Mazur, Marina, Kappes, John C, DeLucas, Lawrence J, Barnes, Stephen, Kirk, Kevin, Tearney, Guillermo J, Rowe, Steven M
Published in American journal of respiratory cell and molecular biology (01.01.2017)
Published in American journal of respiratory cell and molecular biology (01.01.2017)
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A Novel Proteolytic Cascade Generates an Extracellular Matrix-Derived Chemoattractant in Chronic Neutrophilic Inflammation
Gaggar, Amit, Jackson, Patricia L, Noerager, Brett D, O'Reilly, Philip J, McQuaid, D. Brent, Rowe, Steven M, Clancy, J. P, Blalock, J. Edwin
Published in The Journal of immunology (1950) (15.04.2008)
Published in The Journal of immunology (1950) (15.04.2008)
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Matrikines are key regulators in modulating the amplitude of lung inflammation in acute pulmonary infection
Akthar, Samia, Patel, Dhiren F., Beale, Rebecca C., Peiró, Teresa, Xu, Xin, Gaggar, Amit, Jackson, Patricia L., Blalock, J. Edwin, Lloyd, Clare M., Snelgrove, Robert J.
Published in Nature communications (24.09.2015)
Published in Nature communications (24.09.2015)
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Innate Immune Cell–Produced IL-17 Sustains Inflammation in Bullous Pemphigoid
Le Jan, Sébastien, Plée, Julie, Vallerand, David, Dupont, Aurélie, Delanez, Elodie, Durlach, Anne, Jackson, Patricia L., Edwin Blalock, J., Bernard, Philippe, Antonicelli, Frank
Published in Journal of investigative dermatology (01.12.2014)
Published in Journal of investigative dermatology (01.12.2014)
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Journal Article
Cigarette Smoke Induces Systemic Defects in Cystic Fibrosis Transmembrane Conductance Regulator Function
VAMSEE RAJU, S, JACKSON, Patricia L, JONES, Caleb W, BOYDSTON, Jeremy A, CLANCY, J. P, BOWEN, Larry E, ACCURSO, Frank J, BLALOCK, J. Edwin, DRANSFIELD, Mark T, ROWE, Steven M, COURVILLE, Clifford A, McNICHOLAS, Carmel M, SLOANE, Peter A, SABBATINI, Gina, TIDWELL, Sherry, LI PING TANG, BO LIU, FORTENBERRY, James A
Published in American journal of respiratory and critical care medicine (01.12.2013)
Published in American journal of respiratory and critical care medicine (01.12.2013)
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Cigarette smoke-induced collagen destruction; key to chronic neutrophilic airway inflammation?
Overbeek, Saskia A, Braber, Saskia, Koelink, Pim J, Henricks, Paul A J, Mortaz, Esmaeil, LoTam Loi, Adele T, Jackson, Patricia L, Garssen, Johan, Wagenaar, Gerry T M, Timens, Wim, Koenderman, Leo, Blalock, J Edwin, Kraneveld, Aletta D, Folkerts, Gert
Published in PloS one (31.01.2013)
Published in PloS one (31.01.2013)
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Microbicidal Activity of Vascular Peroxidase 1 in Human Plasma via Generation of Hypochlorous Acid
HONG LI, ZEHONG CAO, RAY MOORE, D, JACKSON, Patricia L, BARNES, Stephen, LAMBETH, J. David, THANNICKAL, Victor J, GUANGJIE CHENG
Published in Infection and Immunity (01.07.2012)
Published in Infection and Immunity (01.07.2012)
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Tristetraprolin Down-Regulation Contributes to Persistent TNF-Alpha Expression Induced by Cigarette Smoke Extract through a Post-Transcriptional Mechanism
Zhao, Xue-Ke, Che, Pulin, Cheng, Ming-Liang, Zhang, Quan, Mu, Mao, Li, Hong, Luo, Yuan, Liang, Yue-Dong, Luo, Xin-Hua, Gao, Chang-Qing, Jackson, Patricia L, Wells, J Michael, Zhou, Yong, Hu, Meng, Cai, Guoqiang, Thannickal, Victor J, Steele, Chad, Blalock, J Edwin, Han, Xiaosi, Chen, Ching-Yi, Ding, Qiang
Published in PloS one (02.12.2016)
Published in PloS one (02.12.2016)
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Doxycycline improves clinical outcomes during cystic fibrosis exacerbations
Xu, Xin, Abdalla, Tarek, Bratcher, Preston E, Jackson, Patricia L, Sabbatini, Gina, Wells, J Michael, Lou, Xiang-Yang, Quinn, Rebecca, Blalock, J Edwin, Clancy, J P, Gaggar, Amit
Published in The European respiratory journal (01.04.2017)
Published in The European respiratory journal (01.04.2017)
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A Randomized, Placebo-controlled Trial of Roflumilast. Effect on Proline-Glycine-Proline and Neutrophilic Inflammation in Chronic Obstructive Pulmonary Disease
Wells, J Michael, Jackson, Patricia L, Viera, Liliana, Bhatt, Surya P, Gautney, Joshua, Handley, Guy, King, R Wilson, Xu, Xin, Gaggar, Amit, Bailey, William C, Dransfield, Mark T, Blalock, J Edwin
Published in American journal of respiratory and critical care medicine (15.10.2015)
Published in American journal of respiratory and critical care medicine (15.10.2015)
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The development of novel LTA4H modulators to selectively target LTB4 generation
Low, Caroline M., Akthar, Samia, Patel, Dhiren F., Löser, Stephan, Wong, Chi-Tung, Jackson, Patricia L., Blalock, J. Edwin, Hare, Stephen A., Lloyd, Clare M., Snelgrove, Robert J.
Published in Scientific reports (17.03.2017)
Published in Scientific reports (17.03.2017)
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The neutrophil chemoattractant peptide proline-glycine-proline is associated with acute respiratory distress syndrome
Sharma, Nirmal S, Lal, Charitharth Vivek, Li, Jin-Dong, Lou, Xiang-Yang, Viera, Liliana, Abdallah, Tarek, King, Robert W, Sethi, Jaskaran, Kanagarajah, Prashanth, Restrepo-Jaramillo, Ricardo, Sales-Conniff, Amanda, Wei, Shi, Jackson, Patricia L, Blalock, J Edwin, Gaggar, Amit, Xu, Xin
Published in American journal of physiology. Lung cellular and molecular physiology (01.11.2018)
Published in American journal of physiology. Lung cellular and molecular physiology (01.11.2018)
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An extracellular matrix fragment drives epithelial remodeling and airway hyperresponsiveness
Patel, Dhiren F, Peiró, Teresa, Shoemark, Amelia, Akthar, Samia, Walker, Simone A, Grabiec, Aleksander M, Jackson, Patricia L, Hussell, Tracy, Gaggar, Amit, Xu, Xin, Trevor, Jennifer L, Li, Jindong, Steele, Chad, Tavernier, Gael, Blalock, J Edwin, Niven, Robert M, Gregory, Lisa G, Simpson, Angela, Lloyd, Clare M, Snelgrove, Robert J
Published in Science translational medicine (22.08.2018)
Published in Science translational medicine (22.08.2018)
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Journal Article
MMP-9 cleaves SP-D and abrogates its innate immune functions in vitro
Bratcher, Preston E, Weathington, Nathaniel M, Nick, Heidi J, Jackson, Patricia L, Snelgrove, Robert J, Gaggar, Amit
Published in PloS one (30.07.2012)
Published in PloS one (30.07.2012)
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