Structure–Activity Relationship Study of Tertiary Alcohol Hsp90α-Selective Inhibitors with Novel Binding Mode
Mishra, Sanket J., Reynolds, Tyelor S., Merfeld, Taylor, Balch, Maurie, Peng, Shuxia, Deng, Junpeng, Matts, Robert, Blagg, Brian S. J.
Published in ACS medicinal chemistry letters (08.12.2022)
Published in ACS medicinal chemistry letters (08.12.2022)
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Structure of a lipid-bound viral membrane assembly protein reveals a novel modality for interacting with lipid bilayer
Pathak, Prabhat, Peng, Shuxia, Meng, Xiangzhi, Han, Yue, Zhang, Bing, Zhang, Fushun, Xiang, Yan, Deng, Junpeng
Published in Acta crystallographica. Section A, Foundations and advances (20.07.2018)
Published in Acta crystallographica. Section A, Foundations and advances (20.07.2018)
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The Parkinson’s disease kinase LRRK2 autophosphorylates its GTPase domain at multiple sites
Greggio, Elisa, Taymans, Jean-Marc, Zhen, Eugene Yuejun, Ryder, John, Vancraenenbroeck, Renée, Beilina, Alexandra, Sun, Peng, Deng, Junpeng, Jaffe, Howard, Baekelandt, Veerle, Merchant, Kalpana, Cookson, Mark R.
Published in Biochemical and biophysical research communications (20.11.2009)
Published in Biochemical and biophysical research communications (20.11.2009)
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FTIR Study Reveal Intrinsically Disordered Nature of Heat Shock Protein 90
Xie, Aihua, Balch, Maurie, Neto, David, Causey, Oliver, Hendriks, Johnny, Deng, Junpeng, Matts, Robert
Published in Biophysical journal (16.02.2016)
Published in Biophysical journal (16.02.2016)
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A CC' loop decoy peptide blocks the interaction between Act1 and IL-17RA to attenuate IL-17- and IL-25-induced inflammation
Liu, Caini, Swaidani, Shadi, Qian, Wen, Kang, Zizhen, Sun, Paige, Han, Yue, Wang, Chenhui, Gulen, Muhammet Fatih, Yin, Weiguo, Zhang, Chunjiang, Fox, Paul L, Aronica, Mark, Hamilton, Thomas A, Misra, Saurav, Deng, Junpeng, Li, Xiaoxia
Published in Science signaling (01.11.2011)
Published in Science signaling (01.11.2011)
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Structure of the unique SEFIR domain from human interleukin 17 receptor A reveals a composite ligand-binding site containing a conserved [alpha]-helix for Act1 binding and IL-17 signaling
Zhang, Bing, Liu, Caini, Qian, Wen, Han, Yue, Li, Xiaoxia, Deng, Junpeng
Published in Acta crystallographica. Section D, Biological crystallography. (02.09.2015)
Published in Acta crystallographica. Section D, Biological crystallography. (02.09.2015)
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Correction: Crystal Structure of IL-17 Receptor B SEFIR Domain
Zhang, Bing, Liu, Caini, Qian, Wen, Han, Yue, Li, Xiaoxia, Deng, Junpeng
Published in The Journal of immunology (1950) (01.05.2013)
Published in The Journal of immunology (1950) (01.05.2013)
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EF-hand protein, EfhP, specifically binds Ca 2+ and mediates Ca 2+ regulation of virulence in a human pathogen Pseudomonas aeruginosa
Kayastha, Biraj B, Kubo, Aya, Burch-Konda, Jacob, Dohmen, Rosalie L, McCoy, Jacee L, Rogers, Rendi R, Mares, Sergio, Bevere, Justin, Huckaby, Annalisa, Witt, William, Peng, Shuxia, Chaudhary, Bharat, Mohanty, Smita, Barbier, Mariette, Cook, Gabriel, Deng, Junpeng, Patrauchan, Marianna A
Published in Scientific reports (25.05.2022)
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Published in Scientific reports (25.05.2022)
Journal Article
Crystallization of interleukin-18 for structure-based inhibitor design
Krumm, Brian, Meng, Xiangzhi, Xiang, Yan, Deng, Junpeng
Published in Acta crystallographica. Section F, Structural biology communications (01.06.2015)
Published in Acta crystallographica. Section F, Structural biology communications (01.06.2015)
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Journal Article
Crystal structure of interleukin 17 receptor B SEFIR domain
Zhang, Bing, Liu, Caini, Qian, Wen, Han, Yue, Li, Xiaoxia, Deng, Junpeng
Published in The Journal of immunology (1950) (25.01.2013)
Published in The Journal of immunology (1950) (25.01.2013)
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Journal Article
The R1441C mutation alters the folding properties of the ROC domain of LRRK2
Li, Yongchao, Dunn, Laura, Greggio, Elisa, Krumm, Brian, Jackson, Graham S., Cookson, Mark R., Lewis, Patrick A., Deng, Junpeng
Published in Biochimica et biophysica acta (01.12.2009)
Published in Biochimica et biophysica acta (01.12.2009)
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Physical and functional interaction between the ID1 and p65 for activation of NF-κB
Peng, Xiao, Wang, Yuna, Kolli, Swapna, Deng, Junpeng, Li, Li, Wang, Zhixin, Raj, J Usha, Gou, Deming
Published in American Journal of Physiology: Cell Physiology (01.08.2012)
Published in American Journal of Physiology: Cell Physiology (01.08.2012)
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Structures of a key interaction protein from the Trypanosoma brucei editosome in complex with single domain antibodies
Wu, Meiting, Park, Young-Jun, Pardon, Els, Turley, Stewart, Hayhurst, Andrew, Deng, Junpeng, Steyaert, Jan, Hol, Wim G.J.
Published in Journal of structural biology (01.04.2011)
Published in Journal of structural biology (01.04.2011)
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Physical and functional interaction between the ID1 and p65 for activation of NF-[kappa]B
Peng, Xiao, Wang, Yuna, Kolli, Swapna, Deng, Junpeng, Li, Li, Wang, Zhixin, Raj, J Usha, Gou, Deming
Published in American Journal of Physiology: Cell Physiology (01.08.2012)
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Published in American Journal of Physiology: Cell Physiology (01.08.2012)
Journal Article
Selective Inhibition of the Hsp90α Isoform
Mishra, Sanket J., Khandelwal, Anuj, Banerjee, Monimoy, Balch, Maurie, Peng, Shuxia, Davis, Rachel E., Merfeld, Taylor, Munthali, Vitumbiko, Deng, Junpeng, Matts, Robert L., Blagg, Brian S. J.
Published in Angewandte Chemie (03.05.2021)
Published in Angewandte Chemie (03.05.2021)
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