Exosome secretion is a key pathway for clearance of pathological TDP-43
Iguchi, Yohei, Eid, Lara, Parent, Martin, Soucy, Geneviève, Bareil, Christine, Riku, Yuichi, Kawai, Kaori, Takagi, Shinnosuke, Yoshida, Mari, Katsuno, Masahisa, Sobue, Gen, Julien, Jean-Pierre
Published in Brain (London, England : 1878) (01.12.2016)
Published in Brain (London, England : 1878) (01.12.2016)
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Journal Article
Neuroprotection through Excitability and mTOR Required in ALS Motoneurons to Delay Disease and Extend Survival
Saxena, Smita, Roselli, Francesco, Singh, Katyayani, Leptien, Kerstin, Julien, Jean-Pierre, Gros-Louis, Francois, Caroni, Pico
Published in Neuron (Cambridge, Mass.) (02.10.2013)
Published in Neuron (Cambridge, Mass.) (02.10.2013)
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Journal Article
Neurofilaments: neurobiological foundations for biomarker applications
Gafson, Arie R, Barthélemy, Nicolas R, Bomont, Pascale, Carare, Roxana O, Durham, Heather D, Julien, Jean-Pierre, Kuhle, Jens, Leppert, David, Nixon, Ralph A, Weller, Roy O, Zetterberg, Henrik, Matthews, Paul M
Published in Brain (London, England : 1878) (01.07.2020)
Published in Brain (London, England : 1878) (01.07.2020)
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Journal Article
Inflammation Induces TDP-43 Mislocalization and Aggregation
Correia, Ana Sofia, Patel, Priyanka, Dutta, Kallol, Julien, Jean-Pierre
Published in PloS one (07.10.2015)
Published in PloS one (07.10.2015)
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Journal Article
Breast-Conserving Treatment With or Without Radiotherapy in Ductal Carcinoma In Situ: 15-Year Recurrence Rates and Outcome After a Recurrence, From the EORTC 10853 Randomized Phase III Trial
DONKER, Mila, LITIERE, Saskia, RUTGERS, Emiel J. T, BIJKER, Nina, WERUTSKY, Gustavo, JULIEN, Jean-Pierre, FENTIMAN, Ian S, AGRESTI, Roberto, ROUANET, Philippe, DE LARA, Christine Tunon, BARTELINK, Harry, DUEZ, Nicole
Published in Journal of clinical oncology (10.11.2013)
Published in Journal of clinical oncology (10.11.2013)
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Journal Article
Intracerebroventricular infusion of monoclonal antibody or its derived Fab fragment against misfolded forms of SOD1 mutant delays mortality in a mouse model of ALS
Gros-Louis, Francois, Soucy, Geneviève, Larivière, Roxanne, Julien, Jean-Pierre
Published in Journal of neurochemistry (01.06.2010)
Published in Journal of neurochemistry (01.06.2010)
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Journal Article
The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis
Imamura, Keiko, Izumi, Yuishin, Watanabe, Akira, Tsukita, Kayoko, Woltjen, Knut, Yamamoto, Takuya, Hotta, Akitsu, Kondo, Takayuki, Kitaoka, Shiho, Ohta, Akira, Tanaka, Akito, Watanabe, Dai, Morita, Mitsuya, Takuma, Hiroshi, Tamaoka, Akira, Kunath, Tilo, Wray, Selina, Furuya, Hirokazu, Era, Takumi, Makioka, Kouki, Okamoto, Koichi, Fujisawa, Takao, Nishitoh, Hideki, Homma, Kengo, Ichijo, Hidenori, Julien, Jean-Pierre, Obata, Nanako, Hosokawa, Masato, Akiyama, Haruhiko, Kaneko, Satoshi, Ayaki, Takashi, Ito, Hidefumi, Kaji, Ryuji, Takahashi, Ryosuke, Yamanaka, Shinya, Inoue, Haruhisa
Published in Science translational medicine (24.05.2017)
Published in Science translational medicine (24.05.2017)
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Journal Article
Extracellular mutant SOD1 induces microglial-mediated motoneuron injury
Zhao, Weihua, Beers, David R., Henkel, Jenny S., Zhang, Wei, Urushitani, Makoto, Julien, Jean-Pierre, Appel, Stanley H.
Published in Glia (15.01.2010)
Published in Glia (15.01.2010)
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Journal Article
Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS
Bosco, Daryl A, Brown, Robert H, Morfini, Gerardo, Karabacak, N Murat, Song, Yuyu, Gros-Louis, Francois, Pasinelli, Piera, Goolsby, Holly, Fontaine, Benjamin A, Lemay, Nathan, McKenna-Yasek, Diane, Frosch, Matthew P, Agar, Jeffrey N, Julien, Jean-Pierre, Brady, Scott T
Published in Nature neuroscience (01.11.2010)
Published in Nature neuroscience (01.11.2010)
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Journal Article
Misfolded SOD1 pathology in sporadic Amyotrophic Lateral Sclerosis
Paré, Bastien, Lehmann, Manuela, Beaudin, Marie, Nordström, Ulrika, Saikali, Stephan, Julien, Jean-Pierre, Gilthorpe, Jonathan D., Marklund, Stefan L., Cashman, Neil R., Andersen, Peter M., Forsberg, Karin, Dupré, Nicolas, Gould, Peter, Brännström, Thomas, Gros-Louis, François
Published in Scientific reports (21.09.2018)
Published in Scientific reports (21.09.2018)
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Journal Article
Induction of autophagy mitigates TDP-43 pathology and translational repression of neurofilament mRNAs in mouse models of ALS/FTD
Kumar, Sunny, Phaneuf, Daniel, Cordeau, Jr, Pierre, Boutej, Hejer, Kriz, Jasna, Julien, Jean-Pierre
Published in Molecular neurodegeneration (07.01.2021)
Published in Molecular neurodegeneration (07.01.2021)
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Journal Article
Adeno-associated Virus–mediated Delivery of a Recombinant Single-chain Antibody Against Misfolded Superoxide Dismutase for Treatment of Amyotrophic Lateral Sclerosis
Patel, Priyanka, Kriz, Jasna, Gravel, Mathieu, Soucy, Geneviève, Bareil, Christine, Gravel, Claude, Julien, Jean-Pierre
Published in Molecular therapy (01.03.2014)
Published in Molecular therapy (01.03.2014)
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