The dynamic plasticity of insulin production in β-cells
Boland, Brandon B, Rhodes, Christopher J, Grimsby, Joseph S
Published in Molecular metabolism (Germany) (01.09.2017)
Published in Molecular metabolism (Germany) (01.09.2017)
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Journal Article
Differences in levels of phosphatidylinositols in healthy and stable Coronary Artery Disease subjects revealed by HILIC-MRM method with SERRF normalization
Huang, Yue, Mu, Ruipeng, Wen, David, Grimsby, Joseph S, Liang, Meina, Rosenbaum, Anton I
Published in PloS one (04.06.2021)
Published in PloS one (04.06.2021)
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Journal Article
The prevalence of low muscle mass associated with obesity in the USA
Murdock, Dana J, Wu, Ning, Grimsby, Joseph S, Calle, Roberto A, Donahue, Stephen, Glass, David J, Sleeman, Mark W, Sanchez, Robert J
Published in Skeletal muscle (21.12.2022)
Published in Skeletal muscle (21.12.2022)
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Journal Article
Characterization of Signaling Pathways Associated with Pancreatic β-cell Adaptive Flexibility in Compensation of Obesity-linked Diabetes in db/db Mice
Kang, Taewook, Boland, Brandon B., Jensen, Pia, Alarcon, Cristina, Nawrocki, Arkadiusz, Grimsby, Joseph S., Rhodes, Christopher J., Larsen, Martin R.
Published in Molecular & cellular proteomics (01.06.2020)
Published in Molecular & cellular proteomics (01.06.2020)
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Journal Article
Proteomic Analysis of Restored Insulin Production and Trafficking in Obese Diabetic Mouse Pancreatic Islets Following Euglycemia
Kang, Taewook, Boland, Brandon B, Alarcon, Cristina, Grimsby, Joseph S, Rhodes, Christopher J, Larsen, Martin R
Published in Journal of proteome research (06.09.2019)
Published in Journal of proteome research (06.09.2019)
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Journal Article
Pancreatic β-Cell Rest Replenishes Insulin Secretory Capacity and Attenuates Diabetes in an Extreme Model of Obese Type 2 Diabetes
Boland, Brandon B, Brown, Jr, Charles, Boland, Michelle L, Cann, Jennifer, Sulikowski, Michal, Hansen, Gitte, Grønlund, Rikke V, King, Wanda, Rondinone, Cristina, Trevaskis, James, Rhodes, Christopher J, Grimsby, Joseph S
Published in Diabetes (New York, N.Y.) (01.01.2019)
Published in Diabetes (New York, N.Y.) (01.01.2019)
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Journal Article
1200-P: The Prevalence of Obesity-Associated Loss of Lean Muscle Mass
MURDOCK, DANA J., WU, NING, GLASS, DAVID J., GRIMSBY, JOSEPH S., CALLE, ROBERTO A., DONAHUE, STEPHEN, SLEEMAN, MARK, SANCHEZ, ROBERT J.
Published in Diabetes (New York, N.Y.) (01.06.2022)
Published in Diabetes (New York, N.Y.) (01.06.2022)
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Journal Article
Blocking endothelial lipase with monoclonal antibody MEDI5884 durably increases high density lipoprotein in nonhuman primates and in a phase 1 trial
Le Lay, John E, Du, Qun, Mehta, Minal B, Bhagroo, Nicholas, Hummer, B Timothy, Falloon, Judith, Carlson, Glenn, Rosenbaum, Anton I, Jin, ChaoYu, Kimko, Holly, Tsai, Lan-Feng, Novick, Steven, Cook, Bill, Han, David, Han, Chang Yeop, Vaisar, Tomas, Chait, Alan, Karathanasis, Sotirios K, Rhodes, Christopher J, Hirshberg, Boaz, Damschroder, Melissa M, Hsia, Judith, Grimsby, Joseph S
Published in Science translational medicine (21.04.2021)
Published in Science translational medicine (21.04.2021)
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Journal Article
Peptide-YY3-36/glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic β-cell function and synergistic activation of discrete hypothalamic and brainstem neuronal circuitries
Boland, Brandon B., Laker, Rhianna C., O'Brien, Siobhan, Sitaula, Sadichha, Sermadiras, Isabelle, Nielsen, Jens Christian, Barkholt, Pernille, Roostalu, Urmas, Hecksher-Sørensen, Jacob, Sejthen, Sara Rubek, Thorbek, Ditte Dencker, Suckow, Arthur, Burmeister, Nicole, Oldham, Stephanie, Will, Sarah, Howard, Victor G., Gill, Benji M., Newton, Philip, Naylor, Jacqueline, Hornigold, David C., Austin, Jotham, Lantier, Louise, McGuinness, Owen P., Trevaskis, James L., Grimsby, Joseph S., Rhodes, Christopher J.
Published in Molecular metabolism (Germany) (01.01.2022)
Published in Molecular metabolism (Germany) (01.01.2022)
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Journal Article
Targeted drug delivery via caveolae-associated protein PV1 improves lung fibrosis
Marchetti, Gabriela M., Burwell, Timothy J., Peterson, Norman C., Cann, Jennifer A., Hanna, Richard N., Li, Qing, Ongstad, Emily L., Boyd, Jonathan T., Kennedy, Maureen A., Zhao, Weiguang, Rickert, Keith W., Grimsby, Joseph S., Dall’Acqua, William F., Wu, Herren, Tsui, Ping, Borrok, M. Jack, Gupta, Ruchi
Published in Communications biology (07.03.2019)
Published in Communications biology (07.03.2019)
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Journal Article
2,3-Disubstituted acrylamides as potent glucokinase activators
Sidduri, Achyutharao, Grimsby, Joseph S., Corbett, Wendy L., Sarabu, Ramakanth, Grippo, Joseph F., Lou, Jianping, Kester, Robert F., Dvorozniak, Mark, Marcus, Linda, Spence, Cheryl, Racha, Jagdish K., Moore, David J.
Published in Bioorganic & medicinal chemistry letters (01.10.2010)
Published in Bioorganic & medicinal chemistry letters (01.10.2010)
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Journal Article
Pancreatic ß-Cell Rest Replenishes Insulin Secretory Capacity and Attenuates Diabetes in an Extreme Model of Obese Type 2 Diabetes
Boland, Brandon B, Brown, Charles, Boland, Michelle L, Cann, Jennifer, Sulikowski, Michal, Grimsby, Joseph S, King, Wanda, Rhodes, Christopher J, Trevaskis, James, Rondinone, Cristina, Hansen, Gitte, Grønlund, Rikke V
Published in Diabetes (New York, N.Y.) (01.01.2019)
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Published in Diabetes (New York, N.Y.) (01.01.2019)
Journal Article
Characterization of Signaling Pathways Associated with Pancreatic β-cell Adaptive Flexibility in Compensation of Obesity-linked Diabetes in db/db Mice
Kang, Taewook, Boland, Brandon B, Jensen, Pia, Alarcon, Cristina, Nawrocki, Arkadiusz, Grimsby, Joseph S, Rhodes, Christopher J, Larsen, Martin R
Published in Molecular & cellular proteomics (01.06.2020)
Get full text
Published in Molecular & cellular proteomics (01.06.2020)
Journal Article
Peptide-YY 3-36 /glucagon-like peptide-1 combination treatment of obese diabetic mice improves insulin sensitivity associated with recovered pancreatic β-cell function and synergistic activation of discrete hypothalamic and brainstem neuronal circuitries
Boland, Brandon B, Laker, Rhianna C, O'Brien, Siobhan, Sitaula, Sadichha, Sermadiras, Isabelle, Nielsen, Jens Christian, Barkholt, Pernille, Roostalu, Urmas, Hecksher-Sørensen, Jacob, Sejthen, Sara Rubek, Thorbek, Ditte Dencker, Suckow, Arthur, Burmeister, Nicole, Oldham, Stephanie, Will, Sarah, Howard, Victor G, Gill, Benji M, Newton, Philip, Naylor, Jacqueline, Hornigold, David C, Austin, Jotham, Lantier, Louise, McGuinness, Owen P, Trevaskis, James L, Grimsby, Joseph S, Rhodes, Christopher J
Published in Molecular metabolism (Germany) (01.01.2022)
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Published in Molecular metabolism (Germany) (01.01.2022)
Journal Article
ANTI-PCSK9-GLP-1 FUSIONS AND METHODS FOR USE
SEAMAN, JONATHAN, GRIMSBY, JOSEPH S, CELESTE, ANTHONY J, RAVN, PETER, FAIRMAN, DAVID, BUCHANAN, ANDREW G, RONDINONE, CRISTINA M, CHODORGE, MATTHIEU
Year of Publication 27.08.2015
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Year of Publication 27.08.2015
Patent
Substituted-cycloalkyl and oxygenated-cycloalkyl glucokinase activators
GRIMSBY JOSEPH S, KESTER ROBERT F, RACHA JAGDISH K, CORBETT WENDY L, MAHANEY PAIGE E, SARABU RAMAKANTH, HAYNES NANCY-ELLEN, WANG KA
Year of Publication 10.08.2006
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Year of Publication 10.08.2006
Patent
FUSED HETEROAROMATIC GLUCOKINASE ACTIVATORS
GRIMSBY JOSEPH S, KESTER ROBERT F, CORBETT WENDY L, MAHANEY PAIGE E, SARABU RAMAKANTH, HAYNES NANCY-ELLEN
Year of Publication 15.08.2002
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Year of Publication 15.08.2002
Patent
ACTIVADORES CICLOALQUIL SUSTITUIDOS Y CICLOALQUIL OXIGENADOS DE GLUCOQUINASA
JOSEPH S. GRIMSBY, RAMAKANTH SARABU, JAGDISH K. RACHA, ROBERT F.KESTER, NANCY-ELLEN HAYNES, KA WANG, PAIGE E. MAHENEY, WENDY L. CORBETT
Year of Publication 31.10.2003
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Year of Publication 31.10.2003
Patent