Chemical and Computational Methods for the Characterization of Covalent Reactive Groups for the Prospective Design of Irreversible Inhibitors
Flanagan, Mark E, Abramite, Joseph A, Anderson, Dennis P, Aulabaugh, Ann, Dahal, Upendra P, Gilbert, Adam M, Li, Chao, Montgomery, Justin, Oppenheimer, Stacey R, Ryder, Tim, Schuff, Brandon P, Uccello, Daniel P, Walker, Gregory S, Wu, Yan, Brown, Matthew F, Chen, Jinshan M, Hayward, Matthew M, Noe, Mark C, Obach, R. Scott, Philippe, Laurence, Shanmugasundaram, Veerabahu, Shapiro, Michael J, Starr, Jeremy, Stroh, Justin, Che, Ye
Published in Journal of medicinal chemistry (11.12.2014)
Published in Journal of medicinal chemistry (11.12.2014)
Get full text
Journal Article
A Site-Selective Dual Anchoring Strategy for Artificial Metalloprotein Design
Carey, James R, Ma, Steven K, Pfister, Thomas D, Garner, Dewain K, Kim, Hyeon K, Abramite, Joseph A, Wang, Zhilin, Guo, Zijian, Lu, Yi
Published in Journal of the American Chemical Society (08.09.2004)
Published in Journal of the American Chemical Society (08.09.2004)
Get full text
Journal Article
Regioselective Ring Opening of Di-isopropylsilylenes Derived from 1,3-Diols with Alkyl Lithium Reagents
Chando, Katelyn M, Bailey, Patricia A, Abramite, Joseph A, Sammakia, Tarek
Published in Organic letters (06.11.2015)
Published in Organic letters (06.11.2015)
Get full text
Journal Article
Pyridone Methylsulfone Hydroxamate LpxC Inhibitors for the Treatment of Serious Gram-Negative Infections
Montgomery, Justin I, Brown, Matthew F, Reilly, Usa, Price, Loren M, Abramite, Joseph A, Arcari, Joel, Barham, Rose, Che, Ye, Chen, Jinshan Michael, Chung, Seung Won, Collantes, Elizabeth M, Desbonnet, Charlene, Doroski, Matthew, Doty, Jonathan, Engtrakul, Juntyma J, Harris, Thomas M, Huband, Michael, Knafels, John D, Leach, Karen L, Liu, Shenping, Marfat, Anthony, McAllister, Laura, McElroy, Eric, Menard, Carol A, Mitton-Fry, Mark, Mullins, Lisa, Noe, Mark C, O’Donnell, John, Oliver, Robert, Penzien, Joseph, Plummer, Mark, Shanmugasundaram, Veerabahu, Thoma, Christy, Tomaras, Andrew P, Uccello, Daniel P, Vaz, Alfin, Wishka, Donn G
Published in Journal of medicinal chemistry (23.02.2012)
Published in Journal of medicinal chemistry (23.02.2012)
Get full text
Journal Article
Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections
Brown, Matthew F, Reilly, Usa, Abramite, Joseph A, Arcari, Joel T, Oliver, Robert, Barham, Rose A, Che, Ye, Chen, Jinshan Michael, Collantes, Elizabeth M, Chung, Seung Won, Desbonnet, Charlene, Doty, Jonathan, Doroski, Matthew, Engtrakul, Juntyma J, Harris, Thomas M, Huband, Michael, Knafels, John D, Leach, Karen L, Liu, Shenping, Marfat, Anthony, Marra, Andrea, McElroy, Eric, Melnick, Michael, Menard, Carol A, Montgomery, Justin I, Mullins, Lisa, Noe, Mark. C, O’Donnell, John, Penzien, Joseph, Plummer, Mark S, Price, Loren M, Shanmugasundaram, Veerabahu, Thoma, Christy, Uccello, Daniel P, Warmus, Joseph S, Wishka, Donn G
Published in Journal of medicinal chemistry (26.01.2012)
Published in Journal of medicinal chemistry (26.01.2012)
Get full text
Journal Article
Discovery of Dap‑3 Polymyxin Analogues for the Treatment of Multidrug-Resistant Gram-Negative Nosocomial Infections
Magee, Thomas V, Brown, Matthew F, Starr, Jeremy T, Ackley, David C, Abramite, Joseph A, Aubrecht, Jiri, Butler, Andrew, Crandon, Jared L, Dib-Hajj, Fadia, Flanagan, Mark E, Granskog, Karl, Hardink, Joel R, Huband, Michael D, Irvine, Rebecca, Kuhn, Michael, Leach, Karen L, Li, Bryan, Lin, Jian, Luke, David R, MacVane, Shawn H, Miller, Alita A, McCurdy, Sandra, McKim, James M, Nicolau, David P, Nguyen, Thuy-Trinh, Noe, Mark C, O’Donnell, John P, Seibel, Scott B, Shen, Yue, Stepan, Antonia F, Tomaras, Andrew P, Wilga, Paul C, Zhang, Li, Xu, Jinfeng, Chen, Jinshan Michael
Published in Journal of medicinal chemistry (27.06.2013)
Published in Journal of medicinal chemistry (27.06.2013)
Get full text
Journal Article
Heterocyclic methylsulfone hydroxamic acid LpxC inhibitors as Gram-negative antibacterial agents
McAllister, Laura A., Montgomery, Justin I., Abramite, Joseph A., Reilly, Usa, Brown, Matthew F., Chen, Jinshan M., Barham, Rose A., Che, Ye, Chung, Seung Won, Menard, Carol A., Mitton-Fry, Mark, Mullins, Lisa M., Noe, Mark C., O’Donnell, John P., Oliver, Robert M., Penzien, Joseph B., Plummer, Mark, Price, Loren M., Shanmugasundaram, Veerabahu, Tomaras, Andrew P., Uccello, Daniel P.
Published in Bioorganic & medicinal chemistry letters (15.11.2012)
Published in Bioorganic & medicinal chemistry letters (15.11.2012)
Get full text
Journal Article
One-Pot (1-Ethoxycarbonylcyclopropyl)triphenylphosphonium Tetrafluoroborate Ring-Opening and Wittig Reaction
Chung, Seung Won, Plummer, Mark S, McAllister, Laura A, Oliver, Robert M, Abramite, Joseph A, Shen, Yue, Sun, Jianmin, Uccello, Daniel P, Arcari, Joel T, Price, Loren M, Montgomery, Justin I
Published in Organic letters (07.10.2011)
Published in Organic letters (07.10.2011)
Get full text
Journal Article
Blue Ferrocenium Azurin: An Organometalloprotein with Tunable Redox Properties
Hwang, Hee Jung, Carey, James R, Brower, Evan T, Gengenbach, Alan J, Abramite, Joseph A, Lu, Yi
Published in Journal of the American Chemical Society (09.11.2005)
Published in Journal of the American Chemical Society (09.11.2005)
Get full text
Journal Article
HETEROARYL SULFONE-BASED CONJUGATION HANDLES, METHODS FOR THEIR PREPARATION, AND THEIR USE IN SYNTHESIZING ANTIBODY DRUG CONJUGATES
JOSEPH A ABRAMITE, DANIEL P UCCELLO, LAWRENCE N TUMEY, GARY FREDERICK FILZEN, JENNIFER YOUNG, ADAM MATTHEW GILBERT, LEE R ROBERTS, JEFFREY M CASAVANT, LUDIVINE MOINE, MARK EDWARD FLANAGAN, O'DONNELL CHRISTOPHER JOHN, CHE YE, JEREMY STARR, RUSSELL GEORGE DUSHIN
Year of Publication 12.04.2018
Get full text
Year of Publication 12.04.2018
Patent
Heteroaryl sulfone-based conjugation handles, methods for their preparation, and their use in synthesizing antibody drug conjugates
Filzen, Gary Frederick, Che, Ye, Young, Jennifer, Dushin, Russell George, Starr, Jeremy, Abramite, Joseph A, Gilbert, Adam Matthew, O'Donnell, Christopher John, Uccello, Daniel P, Casavant, Jeffrey M, Moine, Ludivine, Flanagan, Mark, Tumey, Lawrence N, Roberts, Lee R
Year of Publication 01.08.2023
Get full text
Year of Publication 01.08.2023
Patent
HETEROARYL SULFONE-BASED CONJUGATION HANDLES, METHODS FOR THEIR PREPARATION, AND THEIR USE IN SYNTHESIZING ANTIBODY DRUG CONJUGATES
MOINE, LUDIVINE, UCCELLO, DANIEL P, FILZEN, GARY FREDERICK, CHE, YE, TUMEY, LAWRENCE N, ABRAMITE, JOSEPH A, FLANAGAN, MARK EDWARD, ROBERTS, LEE, GILBERT, ADAM MATTHEW, O'DONNELL, CHRISTOPHER JOHN, DUSHIN, RUSSELL GEORGE, YOUNG, JENNIFER, STARR, JEREMY, CASAVANT, JEFFREY M
Year of Publication 19.04.2022
Get full text
Year of Publication 19.04.2022
Patent
HETEROARYL SULFONE-BASED CONJUGATION HANDLES, METHODS FOR THEIR PREPARATION, AND THEIR USE IN SYNTHESIZING ANTIBODY DRUG CONJUGATES
ROBERTS, Lee R, ABRAMITE, Joseph A, YOUNG, Jennifer, STARR, Jeremy, FILZEN, Gary Frederick, FLANAGAN, Mark, GILBERT, Adam Matthew, DUSHIN, Russell George, CHE, Ye, CASAVANT, Jeffrey M, MOINE, Ludivine, O'DONNELL, Christopher John, UCCELLO, Daniel P, TUMEY, Lawrence N
Year of Publication 07.10.2021
Get full text
Year of Publication 07.10.2021
Patent
HETEROARYL SULFONE-BASED CONJUGATION HANDLES, METHODS FOR THEIR PREPARATION, AND THEIR USE IN SYNTHESIZING ANTIBODY DRUG CONJUGATES
FLANAGAN, Mark Edward, ABRAMITE, Joseph A, YOUNG, Jennifer, FILZEN, Gary Frederick, STARR, Jeremy, GILBERT, Adam Matthew, DUSHIN, Russell George, ROBERTS, Lee, CHE, Ye, CASAVANT, Jeffrey M, MOINE, Ludivine, O'DONNELL, Christopher John, UCCELLO, Daniel P, TUMEY, Lawrence N
Year of Publication 12.06.2019
Get full text
Year of Publication 12.06.2019
Patent
Isoxazole derivatives useful as antibacterial agents
JINSHAN MICHAEL CHEN, MATTHEW F. BROWN, JUSTIN I. MONTGOMERY, USA REILLY, JOSEPH A. ABRAMITE, MICHAEL MELNICK
Year of Publication 31.08.2015
Get full text
Year of Publication 31.08.2015
Patent
Isoxazole derivatives useful as antibacterial agents
MONTGOMERY, JUSTIN I, ABRAMITE, JOSEPH A, MELNICK, MICHAEL, CHEN, JINSHAN MICHAEL, USA, REILLY, BROWN, MATTHEW F
Year of Publication 23.07.2015
Get full text
Year of Publication 23.07.2015
Patent