Regulation of intestinal permeability: The role of proteases
Van Spaendonk, Hanne, Ceuleers, Hannah, Witters, Leonie, Patteet, Eveline, Joossens, Jurgen, Augustyns, Koen, Lambeir, Anne-Marie, De Meester, Ingrid, De Man, Joris G, De Winter, Benedicte Y
Published in World journal of gastroenterology : WJG (28.03.2017)
Published in World journal of gastroenterology : WJG (28.03.2017)
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Journal Article
Visceral hypersensitivity in inflammatory bowel diseases and irritable bowel syndrome: The role of proteases
Ceuleers, Hannah, Van Spaendonk, Hanne, Hanning, Nikita, Heirbaut, Jelena, Lambeir, Anne-Marie, Joossens, Jurgen, Augustyns, Koen, De Man, Joris G, De Meester, Ingrid, De Winter, Benedicte Y
Published in World journal of gastroenterology : WJG (21.12.2016)
Published in World journal of gastroenterology : WJG (21.12.2016)
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Journal Article
Extended Structure–Activity Relationship and Pharmacokinetic Investigation of (4-Quinolinoyl)glycyl-2-cyanopyrrolidine Inhibitors of Fibroblast Activation Protein (FAP)
Jansen, Koen, Heirbaut, Leen, Verkerk, Robert, Cheng, Jonathan D, Joossens, Jurgen, Cos, Paul, Maes, Louis, Lambeir, Anne-Marie, De Meester, Ingrid, Augustyns, Koen, Van der Veken, Pieter
Published in Journal of medicinal chemistry (10.04.2014)
Published in Journal of medicinal chemistry (10.04.2014)
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Structure–Activity Relationship Studies on Isoindoline Inhibitors of Dipeptidyl Peptidases 8 and 9 (DPP8, DPP9): Is DPP8-Selectivity an Attainable Goal?
Van Goethem, Sebastiaan, Matheeussen, Veerle, Joossens, Jurgen, Lambeir, Anne-Marie, Chen, Xin, De Meester, Ingrid, Haemers, Achiel, Augustyns, Koen, Van der Veken, Pieter
Published in Journal of medicinal chemistry (25.08.2011)
Published in Journal of medicinal chemistry (25.08.2011)
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Journal Article
The Effect of a Novel Serine Protease Inhibitor on Inflammation and Intestinal Permeability in a Murine Colitis Transfer Model
Van Spaendonk, Hanne, Ceuleers, Hannah, Smet, Annemieke, Berg, Maya, Joossens, Jurgen, Van der Veken, Pieter, Francque, Sven M., Lambeir, Anne-Marie, De Man, Joris G., De Meester, Ingrid, Augustyns, Koen, De Winter, Benedicte Y.
Published in Frontiers in pharmacology (24.06.2021)
Published in Frontiers in pharmacology (24.06.2021)
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Journal Article
The Effect of Serine Protease Inhibitors on Visceral Pain in Different Rodent Models With an Intestinal Insult
Ceuleers, Hannah, Hanning, Nikita, De bruyn, Michelle, De Man, Joris G, De Schepper, Heiko U, Li, Qian, Liu, Liansheng, Abrams, Steven, Smet, Annemieke, Joossens, Jurgen, Augustyns, Koen, De Meester, Ingrid, Pasricha, Pankaj J, De Winter, Benedicte Y
Published in Frontiers in pharmacology (02.06.2022)
Published in Frontiers in pharmacology (02.06.2022)
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Journal Article
Local Colonic Administration of a Serine Protease Inhibitor Improves Post-Inflammatory Visceral Hypersensitivity in Rats
Hanning, Nikita, De bruyn, Michelle, Ceuleers, Hannah, Boogaerts, Tim, Berg, Maya, Smet, Annemieke, De Schepper, Heiko U., Joossens, Jurgen, van Nuijs, Alexander L. N., De Man, Joris G., Augustyns, Koen, De Meester, Ingrid, De Winter, Benedicte Y.
Published in Pharmaceutics (29.05.2021)
Published in Pharmaceutics (29.05.2021)
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Journal Article
Synthesis and Antiplasmodial Activity of Aminoalkylamino-Substituted Neocryptolepine Derivatives
El Sayed, Ibrahim, Van der Veken, Pieter, Steert, Koen, Dhooghe, Liene, Hostyn, Steven, Van Baelen, Gitte, Lemière, Guy, Maes, Bert U. W, Cos, Paul, Maes, Louis, Joossens, Jurgen, Haemers, Achiel, Pieters, Luc, Augustyns, Koen
Published in Journal of medicinal chemistry (14.05.2009)
Published in Journal of medicinal chemistry (14.05.2009)
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Journal Article
The effect of pharmacological inhibition of Serine Proteases on neuronal networks in vitro
Van De Vijver, Sebastiaan, Missault, Stephan, Van Soom, Jeroen, Van Der Veken, Pieter, Augustyns, Koen, Joossens, Jurgen, Dedeurwaerdere, Stefanie, Giugliano, Michele
Published in PeerJ (San Francisco, CA) (23.04.2019)
Published in PeerJ (San Francisco, CA) (23.04.2019)
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Journal Article
Selective Glucocorticoid Receptor Properties of GSK866 Analogs with Cysteine Reactive Warheads
Chirumamilla, Chandra S, Palagani, Ajay, Kamaraj, Balu, Declerck, Ken, Verbeek, Marinus W C, Oksana, Ryabtsova, De Bosscher, Karolien, Bougarne, Nadia, Ruttens, Bart, Gevaert, Kris, Houtman, René, De Vos, Winnok H, Joossens, Jurgen, Van Der Veken, Pieter, Augustyns, Koen, Van Ostade, Xaveer, Bogaerts, Annemie, De Winter, Hans, Vanden Berghe, Wim
Published in Frontiers in immunology (01.11.2017)
Published in Frontiers in immunology (01.11.2017)
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Journal Article
Inhibition of dipeptidyl-peptidase IV catalyzed peptide truncation by Vildagliptin ((2S)-{[(3-hydroxyadamantan-1-yl)amino]acetyl}-pyrrolidine-2-carbonitrile)
Brandt, Inger, Joossens, Jurgen, Chen, Xin, Maes, Marie-Berthe, Scharpé, Simon, Meester, Ingrid De, Lambeir, Anne-Marie
Published in Biochemical pharmacology (01.07.2005)
Published in Biochemical pharmacology (01.07.2005)
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Journal Article
Evaluation of Nucleoside Hydrolase Inhibitors for Treatment of African Trypanosomiasis
BERG, Maya, KOHL, Linda, GRELLIER, Philippe, HAEMERS, Achiel, DEGANO, Massimo, MAES, Louis, DE KONING, Harry P, AUGUSTYNS, Koen, VAN DER VEKEN, Pieter, JOOSSENS, Jurgen, AL-SALABI, Mohammed I, CASTAGNA, Valeria, GIANNESE, Francesca, COS, Paul, VERSEES, Wim, STEYAERT, Jan
Published in Antimicrobial Agents and Chemotherapy (01.05.2010)
Published in Antimicrobial Agents and Chemotherapy (01.05.2010)
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Journal Article
Reverse transcriptase inhibitors as microbicides
Lewi, Paul, Heeres, Jan, Ariën, Kevin, Venkatraj, Muthusamy, Joossens, Jurgen, Van der Veken, Pieter, Augustyns, Koen, Vanham, Guido
Published in Current HIV research (01.01.2012)
Published in Current HIV research (01.01.2012)
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Journal Article
Development of triazine non-nucleoside reverse transcriptase inhibitors for microbicidal applications
Ariën, Kevin K, Venkatraj, Muthusamy, Míchiels, Johan, Joossens, Jurgen, der Veken, PieterVan, Heeres, Jan, Abdellati, Said, Cuylaerts, Vicky, Crucitti, Tania, Lewi, Paul, Augustyns, Koen, Vanham, Guido
Published in Retrovirology (03.10.2011)
Published in Retrovirology (03.10.2011)
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Journal Article
Extended Structure Activity Relationship and Pharmacokinetic Investigation of (4-Quinolinoyl)glycy1-2-cyanopyrrolidine Inhibitors of Fibroblast Activation Protein (FAP)
Jansen, Koen, Heirbaut, Leen, Verkerk, Robert, Cheng, Jonathan D., Joossens, Jurgen, Cos, Paul, Maes, Louis, Lambeir, Anne-Marie, De Meester, Ingrid, Augustyns, Koen, Van der Veken, Pieter
Published in Journal of medicinal chemistry (10.04.2014)
Published in Journal of medicinal chemistry (10.04.2014)
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Journal Article
Novel Ferroptosis Inhibitors with Improved Potency and ADME Properties
Hofmans, Sam, Berghe, Tom Vanden, Devisscher, Lars, Hassannia, Behrouz, Lyssens, Sophie, Joossens, Jurgen, Van Der Veken, Pieter, Vandenabeele, Peter, Augustyns, Koen
Published in Journal of medicinal chemistry (10.03.2016)
Published in Journal of medicinal chemistry (10.03.2016)
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Journal Article
Searching for New Leads for Tuberculosis: Design, Synthesis, and Biological Evaluation of Novel 2‑Quinolin-4-yloxyacetamides
Pitta, Eleni, Rogacki, Maciej K, Balabon, Olga, Huss, Sophie, Cunningham, Fraser, Lopez-Roman, Eva Maria, Joossens, Jurgen, Augustyns, Koen, Ballell, Lluis, Bates, Robert H, Van der Veken, Pieter
Published in Journal of medicinal chemistry (28.07.2016)
Published in Journal of medicinal chemistry (28.07.2016)
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Journal Article
Selective Inhibitors of Fibroblast Activation Protein (FAP) with a (4-Quinolinoyl)-glycyl-2-cyanopyrrolidine Scaffold
Jansen, Koen, Heirbaut, Leen, Cheng, Jonathan D, Joossens, Jurgen, Ryabtsova, Oxana, Cos, Paul, Maes, Louis, Lambeir, Anne-Marie, De Meester, Ingrid, Augustyns, Koen, Van der Veken, Pieter
Published in ACS medicinal chemistry letters (09.05.2013)
Published in ACS medicinal chemistry letters (09.05.2013)
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Development of a novel antibody-tetrazine conjugate for bioorthogonal pretargeting
Maggi, Agnese, Ruivo, Eduardo, Fissers, Jens, Vangestel, Christel, Chatterjee, Sneha, Joossens, Jurgen, Sobott, Frank, Staelens, Steven, Stroobants, Sigrid, Van der Veken, Pieter, Wyffels, Leonie, Augustyns, Koen
Published in Organic & biomolecular chemistry (01.01.2016)
Published in Organic & biomolecular chemistry (01.01.2016)
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Journal Article
Discovery and SAR of Novel and Selective Inhibitors of Urokinase Plasminogen Activator (uPA) with an Imidazo[1,2‑a]pyridine Scaffold
Gladysz, Rafaela, Adriaenssens, Yves, De Winter, Hans, Joossens, Jurgen, Lambeir, Anne-Marie, Augustyns, Koen, Van der Veken, Pieter
Published in Journal of medicinal chemistry (10.12.2015)
Published in Journal of medicinal chemistry (10.12.2015)
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