Ricolinostat plus lenalidomide, and dexamethasone in relapsed or refractory multiple myeloma: a multicentre phase 1b trial
Yee, Andrew J, MD, Bensinger, William I, MD, Supko, Jeffrey G, PhD, Voorhees, Peter M, MD, Berdeja, Jesus G, MD, Richardson, Paul G, Prof, Libby, Edward N, MD, Wallace, Ellen E, BA, Birrer, Nicole E, BA, Burke, Jill N, MSN, Tamang, David L, PhD, Yang, Min, PhD, Jones, Simon S, PhD, Wheeler, Catherine A, MD, Markelewicz, Robert J, MD, Raje, Noopur S, Dr
Published in The lancet oncology (01.11.2016)
Published in The lancet oncology (01.11.2016)
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Ricolinostat (ACY‐1215) induced inhibition of aggresome formation accelerates carfilzomib‐induced multiple myeloma cell death
Mishima, Yuko, Santo, Loredana, Eda, Homare, Cirstea, Diana, Nemani, Neeharika, Yee, Andrew J., O'Donnell, Elizabeth, Selig, Martin Karl, Quayle, Steven N., Arastu‐Kapur, Shirin, Kirk, Christopher, Boise, Lawrence H., Jones, Simon S., Raje, Noopur
Published in British journal of haematology (01.05.2015)
Published in British journal of haematology (01.05.2015)
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Enhancement of pomalidomide anti-tumor response with ACY-241, a selective HDAC6 inhibitor
North, Brian J, Almeciga-Pinto, Ingrid, Tamang, David, Yang, Min, Jones, Simon S, Quayle, Steven N
Published in PloS one (06.03.2017)
Published in PloS one (06.03.2017)
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HDAC6 Inhibition Alleviates CLL-Induced T-Cell Dysfunction and Enhances Immune Checkpoint Blockade Efficacy in the Eμ-TCL1 Model
Maharaj, Kamira, Powers, John J, Mediavilla-Varela, Melanie, Achille, Alex, Gamal, Wael, Quayle, Steven, Jones, Simon S, Sahakian, Eva, Pinilla-Ibarz, Javier
Published in Frontiers in immunology (23.11.2020)
Published in Frontiers in immunology (23.11.2020)
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In vitro and in vivo interactions between the HDAC6 inhibitor ricolinostat (ACY1215) and the irreversible proteasome inhibitor carfilzomib in non-Hodgkin lymphoma cells
Dasmahapatra, Girija, Patel, Hiral, Friedberg, Johnathan, Quayle, Steven N, Jones, Simon S, Grant, Steven
Published in Molecular cancer therapeutics (01.12.2014)
Published in Molecular cancer therapeutics (01.12.2014)
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Selective Inhibitors of Histone Deacetylases 1 and 2 Synergize with Azacitidine in Acute Myeloid Leukemia
Min, Chengyin, Moore, Nathan, Shearstone, Jeffrey R, Quayle, Steven N, Huang, Pengyu, van Duzer, John H, Jarpe, Matthew B, Jones, Simon S, Yang, Min
Published in PloS one (06.01.2017)
Published in PloS one (06.01.2017)
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The effects of PRX-07034, a novel 5-HT6 antagonist, on cognitive flexibility and working memory in rats
Mohler, Eric G., Baker, Phillip M., Gannon, Kimberly S., Jones, Simon S., Shacham, Sharon, Sweeney, John A., Ragozzino, Michael E.
Published in Psychopharmacologia (01.04.2012)
Published in Psychopharmacologia (01.04.2012)
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Ricolinostat, the First Selective Histone Deacetylase 6 Inhibitor, in Combination with Bortezomib and Dexamethasone for Relapsed or Refractory Multiple Myeloma
Vogl, Dan T, Raje, Noopur, Jagannath, Sundar, Richardson, Paul, Hari, Parameswaran, Orlowski, Robert, Supko, Jeffrey G, Tamang, David, Yang, Min, Jones, Simon S, Wheeler, Catherine, Markelewicz, Robert J, Lonial, Sagar
Published in Clinical cancer research (01.07.2017)
Published in Clinical cancer research (01.07.2017)
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Preclinical activity, pharmacodynamic, and pharmacokinetic properties of a selective HDAC6 inhibitor, ACY-1215, in combination with bortezomib in multiple myeloma
Santo, Loredana, Hideshima, Teru, Kung, Andrew L., Tseng, Jen-Chieh, Tamang, David, Yang, Min, Jarpe, Matthew, van Duzer, John H., Mazitschek, Ralph, Ogier, Walter C., Cirstea, Diana, Rodig, Scott, Eda, Homare, Scullen, Tyler, Canavese, Miriam, Bradner, James, Anderson, Kenneth C., Jones, Simon S., Raje, Noopur
Published in Blood (15.03.2012)
Published in Blood (15.03.2012)
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Synergistic Immunostimulatory Effects and Therapeutic Benefit of Combined Histone Deacetylase and Bromodomain Inhibition in Non-Small Cell Lung Cancer
Adeegbe, Dennis O, Liu, Yan, Lizotte, Patrick H, Kamihara, Yusuke, Aref, Amir R, Almonte, Christina, Dries, Ruben, Li, Yuyang, Liu, Shengwu, Wang, Xiaoen, Warner-Hatten, Tiquella, Castrillon, Jessica, Yuan, Guo-Cheng, Poudel-Neupane, Neermala, Zhang, Haikuo, Guerriero, Jennifer L, Han, Shiwei, Awad, Mark M, Barbie, David A, Ritz, Jerome, Jones, Simon S, Hammerman, Peter S, Bradner, James, Quayle, Steven N, Wong, Kwok-Kin
Published in Cancer discovery (01.08.2017)
Published in Cancer discovery (01.08.2017)
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Histone deacetylase (HDAC) inhibitors as single agents induce multiple myeloma cell death principally through the inhibition of class I HDAC
Mithraprabhu, Sridurga, Khong, Tiffany, Jones, Simon S., Spencer, Andrew
Published in British journal of haematology (01.08.2013)
Published in British journal of haematology (01.08.2013)
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Retraction: In Vitro and In Vivo Interactions between the HDAC6 Inhibitor Ricolinostat (ACY1215) and the Irreversible Proteasome Inhibitor Carfilzomib in Non-Hodgkin Lymphoma Cells
Dasmahapatra, Girija, Patel, Hiral, Friedberg, Johnathan, Quayle, Steven N, Jones, Simon S, Grant, Steven
Published in Molecular cancer therapeutics (01.06.2019)
Published in Molecular cancer therapeutics (01.06.2019)
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Abstract 3958: Tubulin hyper-acetylation in blood lymphocytes: pharmacodynamic (PD) biomarker for the selective histone deacetylase (HDAC) 6 inhibitors ricolinostat and ACY-241 in multiple myeloma (MM) patients
Tamang, David L., Supko, Jeffery, Bhol, Kailash, Wheeler, Catherine, Jones, Simon S., Yang, Min
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract 4724: Novel and selective inhibitors of histone deacetylases (HDAC) 1 and 2 synergize with DNA methyltransferase inhibitor azacitidine in acute myeloid leukemia (AML)
Min, Chengyin, Quayle, Steven N., Huang, Pengyu, Shearstone, Jeffrey R., Jones, Simon S., Yang, Min
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract 4485: Regulation of chronic lymphocytic leukemia (CLL) immunobiology by histone deacetylase 6 (HDAC6)
Sahakian, Eva, Maharaj, Kamira, Powers, John, Fonesca, Renee M., Deng, Susan, Pinilla-Ibraz, Javier, Quayle, Steven N., Jones, Simon S.
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Abstract 2477: An orally bioavailable and selective histone deacetylase (HDAC) 1 & 2 inhibitor enhances retinoic acid mediated differentiation of neuroblastoma
Tamang, David L., Huang, Pengyu, Golonzhka, Olga, Shearstone, Jeffrey R., Quayle, Steven N., Jones, Simon S., Yang, Min
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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BMP-7 regulates chemokine, cytokine, and hemodynamic gene expression in proximal tubule cells
GOULD, Stephen E, DAY, Maria, JONES, Simon S, DORAI, Haimanti
Published in Kidney international (01.01.2002)
Published in Kidney international (01.01.2002)
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Silencing of HDAC6 as a therapeutic target in chronic lymphocytic leukemia
Maharaj, Kamira, Powers, John J., Achille, Alex, Deng, Susan, Fonseca, Renee, Pabon-Saldana, Mibel, Quayle, Steven N., Jones, Simon S., Villagra, Alejandro, Sotomayor, Eduardo M., Sahakian, Eva, Pinilla-Ibarz, Javier
Published in Blood advances (13.11.2018)
Published in Blood advances (13.11.2018)
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