Tu1401 Factors Contributing to Treatment Satisfaction in Patients With Irritable Bowel Syndrome With Constipation (IBS-C) Treated With Linaclotide vs Placebo
Lembo, Anthony, Carson, Robyn, Shiff, Steven J, Lavins, Bernard J, MacDougall, James E, Shi, Kelvin, Schneier, Harvey, Currie, Mark G, Johnston, Jeffrey M
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)
Get full text
Journal Article
Sa1421 The Effect of Comorbid Psychological Distress on Baseline Irritable Bowel Syndrome With Constipation Symptoms and Response to Linaclotide Treatment
Chey, William D, Spiegel, Brennan M, Lavins, Bernard J, Hao, Xinming, Currie, Mark G, Schneier, Harvey, Johnston, Jeffrey M
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)
Get full text
Journal Article
Tu1380 Assessing the Percent of Days Linaclotide Improved Abdominal Symptoms and Stool Frequency in Patients With IBS-C: A Pooled Analysis of Two Phase 3 Trials
Rao, Satish S, Chang, Lin, Hao, Xinming, Lavins, Bernard J, Shiff, Steven J, Cao, Xiaofan, Schneier, Harvey, Currie, Mark G, Johnston, Jeffrey M
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)
Get full text
Journal Article
Su2033 Determining the Minimum Duration for Initial Treatment With Linaclotide in IBS-C Patients: Results From Pooled Phase 3 Trials
Chey, William D, Lavins, Bernard J, Shiff, Steven J, MacDougall, James E, Kurtz, Caroline B, Shi, Kelvin, Currie, Mark G, Johnston, Jeffrey M
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)
Get full text
Journal Article
Mo2054 Assessing Abdominal and Bowel Symptoms Using Adequate Relief Based Thresholds: Results From 2 Phase 3 Trials of Linaclotide in Patients With Irritable Bowel Syndrome With Constipation
Camilleri, Michael, Lembo, Anthony, Lavins, Bernard J, MacDougall, James E, Shiff, Steven J, Jia, Xinwei D, Currie, Mark G, Kurtz, Caroline B, Johnston, Jeffrey M
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2013)
Get full text
Journal Article
In vitro and pharmacophore-based discovery of novel hPEPT1 inhibitors
Ekins, Sean, Johnston, Jeffrey S, Bahadduri, Praveen, D'Souza, Vanessa M, Ray, Abhijit, Chang, Cheng, Swaan, Peter W
Published in Pharmaceutical research (01.04.2005)
Published in Pharmaceutical research (01.04.2005)
Get full text
Journal Article
Efficacy and Safety of Once-Daily Linaclotide Administered Orally for 26 Weeks in Patients With IBS-C: Results From a Randomized, Double-Blind, Placebo-Controlled Phase 3 Trial
Chey, William D, Lembo, Anthony, MacDougall, James E, Lavins, Bernard J, Schneier, Harvey, Johnston, Jeffrey M
Published in Gastroenterology (New York, N.Y. 1943) (2011)
Published in Gastroenterology (New York, N.Y. 1943) (2011)
Get full text
Journal Article
Preparation of a protected phosphoramidon precursor via an H-Phosphonate coupling strategy
Donahue, Matthew G., Johnston, Jeffrey N.
Published in Bioorganic & medicinal chemistry letters (01.11.2006)
Published in Bioorganic & medicinal chemistry letters (01.11.2006)
Get full text
Journal Article
Brønsted acid-promoted azide-olefin [3 + 2] cycloadditions for the preparation of contiguous aminopolyols: The importance of disiloxane ring size to a diastereoselective, bidirectional approach to zwittermicin A
Muchalski, Hubert, Hong, Ki Bum, Johnston, Jeffrey N
Published in Beilstein journal of organic chemistry (20.12.2010)
Published in Beilstein journal of organic chemistry (20.12.2010)
Get full text
Journal Article
Clarification of trial end points presented in a recent review of linaclotide
Johnston, Jeffrey M, Schneier, Harvey A
Published in Expert review of gastroenterology & hepatology (01.02.2012)
Published in Expert review of gastroenterology & hepatology (01.02.2012)
Get full text
Journal Article
Primate superior colliculus is causally engaged in abstract higher-order cognition
Peysakhovich, Barbara, Zhu, Ou, Tetrick, Stephanie M., Shirhatti, Vinay, Silva, Alessandra A., Li, Sihai, Ibos, Guilhem, Rosen, Matthew C., Johnston, W. Jeffrey, Freedman, David J.
Published in Nature neuroscience (01.10.2024)
Published in Nature neuroscience (01.10.2024)
Get full text
Journal Article
Tu1381 Effects of 26 Weeks of Linaclotide Treatment on Adequate Relief and IBS Severity in Patients With Irritable Bowel Syndrome With Constipation
Chey, William D, Quigley, Eamonn M, Lavins, Bernard J, Baird, Mollie J, Fitch, Donald A, Hao, Xinming, Shi, Kelvin, Currie, Mark G, Schneier, Harvey, Johnston, Jeffrey M
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)
Get full text
Journal Article
Tu1423 Effects of Linaclotide on Straining Associated With Bowel Movements in Patients With Irritable Bowel Syndrome With Constipation (IBS-C): A Post Hoc Analysis of Pooled Data From Two Phase 3 Trials
Lembo, Anthony, Rao, Satish S, Shiff, Steven J, Lavins, Bernard J, MacDougall, James E, Shi, Kelvin, Schneier, Harvey, Currie, Mark G, Johnston, Jeffrey M
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)
Get full text
Journal Article
Sa1094 Developing Benchmarks for Clinically Meaningful Change for IBS-C Symptoms Using Data From Two Phase 3 Trials of Linaclotide
Spiegel, Brennan M, Locke, Giles R, Kurtz, Caroline B, Williams, Valerie, Nelson, Lauren M, Carson, Robyn, Jia, Xinwei D, Currie, Mark G, MacDougall, James E, Schneier, Harvey, Johnston, Jeffrey M
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)
Get full text
Journal Article
848 Efficacy of Linaclotide in Improving Abdominal Symptoms Rated as Most Severe by Patients With Irritable Bowel Syndrome With Constipation (IBS-C)
Rao, Satish S, Quigley, Eamonn M, Shiff, Steven J, Lavins, Bernard J, Kurtz, Caroline B, MacDougall, James E, Shi, Kelvin, Schneier, Harvey, Currie, Mark G, Johnston, Jeffrey M
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)
Get full text
Journal Article
Tu1069 Do Baseline Factors Contribute to Treatment Satisfaction in Patients With Chronic Constipation Treated With Linaclotide vs Placebo?
Schoenfeld, Philip S, Chang, Lin, Carson, Robyn, Shiff, Steven J, Lavins, Bernard J, MacDougall, James E, Jia, Xinwei D, Schneier, Harvey, Currie, Mark G, Johnston, Jeffrey M
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)
Get full text
Journal Article
Tu1068 Effects of Linaclotide Treatment on Patient-Reported Ratings of Change for Symptoms of Irritable Bowel Syndrome With Constipation (IBS-C): Pooled 12-Week Findings From Two Phase 3 Trials
Locke, Giles R, Chey, William D, Kurtz, Caroline B, Carson, Robyn, Baird, Mollie J, MacDougall, James E, Jia, Xinwei D, Currie, Mark G, Schneier, Harvey, Johnston, Jeffrey M
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)
Get full text
Journal Article
Mo1856 Linaclotide Significantly Improved Abdominal Pain Compared With Placebo in Patients With Irritable Bowel Syndrome Regardless of Baseline Pain Severity in Two Phase 3 Trials
Schoenfeld, Philip S, Chey, William D, Lavins, Bernard J, Shiff, Steven J, Kurtz, Caroline B, MacDougall, James E, Jia, Xinwei D, Schneier, Harvey, Currie, Mark G, Johnston, Jeffrey M
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)
Get full text
Journal Article
Sa1098 Mediation Analysis Supports a Direct Effect of Linaclotide on Relief of Abdominal Pain Independent of Constipation Improvement
MacDougall, James E, MacKinnon, David P, Lavins, Bernard J, Lembo, Anthony, Shiff, Steven J, Schneier, Harvey, Hao, Xinming, Currie, Mark G, Johnston, Jeffrey M
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)
Published in Gastroenterology (New York, N.Y. 1943) (01.05.2012)
Get full text
Journal Article