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A positive allosteric modulator of α7 nAChRs augments neuroprotective effects of endogenous nicotinic agonists in cerebral ischaemia
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Johnson, Stephen R., Rikli, Hillary G., Schmidt, Justin O., Evans, M. Steven
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Electrostatic-field and surface-shape similarity for virtual screening and pose prediction
Cleves, Ann E., Johnson, Stephen R., Jain, Ajay N.
Published in Journal of computer-aided molecular design (01.10.2019)
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Approaches for machine learning intermolecular interaction energies and application to energy components from symmetry adapted perturbation theory
Metcalf, Derek P, Koutsoukas, Alexios, Spronk, Steven A, Claus, Brian L, Loughney, Deborah A, Johnson, Stephen R, Cheney, Daniel L, Sherrill, C David
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Tyrosine Kinase 2-mediated Signal Transduction in T Lymphocytes Is Blocked by Pharmacological Stabilization of Its Pseudokinase Domain
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Published in The Journal of biological chemistry (24.04.2015)
Published in The Journal of biological chemistry (24.04.2015)
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Boosting Endogenous Resistance of Brain to Ischemia
Sun, Fen, Johnson, Stephen R., Jin, Kunlin, Uteshev, Victor V.
Published in Molecular neurobiology (01.04.2017)
Published in Molecular neurobiology (01.04.2017)
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A positive allosteric modulator of alpha 7 nAChRs augments neuroprotective effects of endogenous nicotinic agonists in cerebral ischaemia
Kalappa, Bopanna I, Sun, Fen, Johnson, Stephen R, Jin, Kunlin, Uteshev, Victor V
Published in British journal of pharmacology (01.08.2013)
Published in British journal of pharmacology (01.08.2013)
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Molecular Properties That Influence the Oral Bioavailability of Drug Candidates
Veber, Daniel F, Johnson, Stephen R, Cheng, Hung-Yuan, Smith, Brian R, Ward, Keith W, Kopple, Kenneth D
Published in Journal of medicinal chemistry (06.06.2002)
Published in Journal of medicinal chemistry (06.06.2002)
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Structure-based amelioration of PXR transactivation in a novel series of macrocyclic allosteric inhibitors of HIV-1 integrase
Sivaprakasam, Prasanna, Wang, Zhongyu, Meanwell, Nicholas A., Khan, Javed A., Langley, David R., Johnson, Stephen R., Li, Guo, Pendri, Annapurna, Connolly, Timothy P., Gao, Mian, Camac, Daniel M., Klakouski, Cheryl, Zvyaga, Tatyana, Cianci, Christopher, McAuliffe, Brian, Ding, Bo, Discotto, Linda, Krystal, Mark R., Jenkins, Susan, Peese, Kevin M., Narasimhulu Naidu, B.
Published in Bioorganic & medicinal chemistry letters (15.11.2020)
Published in Bioorganic & medicinal chemistry letters (15.11.2020)
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Benzonatate inhibition of voltage-gated sodium currents
Evans, M. Steven, Maglinger, G. Benton, Fletcher, Anita M., Johnson, Stephen R.
Published in Neuropharmacology (01.02.2016)
Published in Neuropharmacology (01.02.2016)
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Trends in Kinase Selectivity: Insights for Target Class-Focused Library Screening
Posy, Shana L, Hermsmeier, Mark A, Vaccaro, Wayne, Ott, Karl-Heinz, Todderud, Gordon, Lippy, Jonathan S, Trainor, George L, Loughney, Deborah A, Johnson, Stephen R
Published in Journal of medicinal chemistry (13.01.2011)
Published in Journal of medicinal chemistry (13.01.2011)
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