Discovery of Evobrutinib: An Oral, Potent, and Highly Selective, Covalent Bruton’s Tyrosine Kinase (BTK) Inhibitor for the Treatment of Immunological Diseases
Caldwell, Richard D, Qiu, Hui, Askew, Ben C, Bender, Andrew T, Brugger, Nadia, Camps, Montserrat, Dhanabal, Mohanraj, Dutt, Vikram, Eichhorn, Thomas, Gardberg, Anna S, Goutopoulos, Andreas, Grenningloh, Roland, Head, Jared, Healey, Brian, Hodous, Brian L, Huck, Bayard R, Johnson, Theresa L, Jones, Christopher, Jones, Reinaldo C, Mochalkin, Igor, Morandi, Federica, Nguyen, Ngan, Meyring, Michael, Potnick, Justin R, Santos, Dusica Cvetinovic, Schmidt, Ralf, Sherer, Brian, Shutes, Adam, Urbahns, Klaus, Follis, Ariele Viacava, Wegener, Ansgar A, Zimmerli, Simone C, Liu-Bujalski, Lesley
Published in Journal of medicinal chemistry (12.09.2019)
Published in Journal of medicinal chemistry (12.09.2019)
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Journal Article
Discovery of M5049: A Novel Selective Toll-Like Receptor 7/8 Inhibitor for Treatment of Autoimmunity
Vlach, Jaromir, Bender, Andrew T, Przetak, Melinda, Pereira, Albertina, Deshpande, Aditee, Johnson, Theresa L, Reissig, Sonja, Tzvetkov, Evgeni, Musil, Djordje, Morse, Noune Tahmassian, Haselmayer, Philipp, Zimmerli, Simone C, Okitsu, Shinji L, Walsky, Robert L, Sherer, Brian
Published in The Journal of pharmacology and experimental therapeutics (01.03.2021)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2021)
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Journal Article
Discovery of novel Cyclophilin D inhibitors starting from three dimensional fragments with millimolar potencies
Grädler, Ulrich, Schwarz, Daniel, Blaesse, Michael, Leuthner, Birgitta, Johnson, Theresa L., Bernard, Frederic, Jiang, Xuliang, Marx, Andreas, Gilardone, Marine, Lemoine, Hugues, Roche, Didier, Jorand-Lebrun, Catherine
Published in Bioorganic & medicinal chemistry letters (01.12.2019)
Published in Bioorganic & medicinal chemistry letters (01.12.2019)
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Journal Article
Chronic shoulder pain
Crookes, Thomas, Wall, Chris, Byrnes, Jason, Johnson, Theresa, Gill, David
Published in Australian journal of general practice (01.11.2023)
Published in Australian journal of general practice (01.11.2023)
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Journal Article
Symptom management for patients awaiting joint replacement surgery
Wall, Chris, Johnson, Theresa, de Steiger, Richard
Published in Australian journal of general practice (01.07.2020)
Published in Australian journal of general practice (01.07.2020)
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Journal Article
Clinical characteristics and social determinants of health associated with 30-day hospital readmissions of patients with COVID-19
Wiley, Zanthia, Kulshreshtha, Ambar, Li, Dong, Kubes, Julianne, Kandiah, Sheetal, Leung, Serena, Kobaidze, Ketino, Shin, Sangmin Ryan, Moanna, Abeer, Perkins, Jonathan, Hogan, Matthew, Sims, Kanika M, Amzat, Tolu, Cantos, Valeria D, Elutilo-Ayoola, Temitope, Hanna, Jasmah, Harris, Nadine M, Henry, Tracey L, Iheaku, Onyinye, Japaridze, Mariam, Lanka, Vaishnavi, Johnson, Theresa A, Mbaezue, Nkechi, Rebolledo, Paulina A, Sexton, Mary Elizabeth, Surapaneni, Phani Keerthi, Franks, Nicole
Published in Journal of investigative medicine (01.08.2022)
Published in Journal of investigative medicine (01.08.2022)
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Journal Article
Pre-clinical studies of EC2629, a highly potent folate- receptor-targeted DNA crosslinking agent
Reddy, Joseph A., Nelson, Melissa, Dircksen, Christina, Vetzel, Marilynn, Johnson, Theresa, Cross, Vicky, Westrick, Elaine, Qi, LongWu, Hahn, Spencer, Santhapuram, Hari Krishna, Parham, Garth, Wang, Kevin, Vaughn, Jeremy F., Felten, Albert, Pugh, Michael, Lu, June, Klein, Patrick, Vlahov, Iontcho R., Leamon, Christopher P.
Published in Scientific reports (29.07.2020)
Published in Scientific reports (29.07.2020)
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Journal Article
Structure of the Catalytic Domain of Human Polo-like Kinase 1
Kothe, Michael, Kohls, Darcy, Low, Simon, Coli, Rocco, Cheng, Alan C, Jacques, Suzanne L, Johnson, Theresa L, Lewis, Cristina, Loh, Christine, Nonomiya, Jim, Sheils, Alissa L, Verdries, Kimberly A, Wynn, Thomas A, Kuhn, Cyrille, Ding, Yuan-Hua
Published in Biochemistry (Easton) (22.05.2007)
Published in Biochemistry (Easton) (22.05.2007)
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Journal Article
Heat stress causes oxidative stress but not inflammatory signaling in porcine skeletal muscle
Montilla, Sandra I Rosado, Johnson, Theresa P, Pearce, Sarah C, Gardan-Salmon, Delphine, Gabler, Nicholas K, Ross, Jason W, Rhoads, Robert P, Baumgard, Lance H, Lonergan, Steven M, Selsby, Joshua T
Published in Temperature (Austin) (30.06.2014)
Published in Temperature (Austin) (30.06.2014)
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Journal Article
Molecular Dynamics Simulation and Binding Energy Calculation for Estimation of Oligonucleotide Duplex Thermostability in RNA-Based Therapeutics
Shen, Lingling, Johnson, Theresa L, Clugston, Susan, Huang, Hongwei, Butenhof, Kenneth J, Stanton, Robert V
Published in Journal of chemical information and modeling (22.08.2011)
Published in Journal of chemical information and modeling (22.08.2011)
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Journal Article
The Guatemalan echocardiographic network
Robicsek, Francis, Molina, Raúl Cruz, Johnson, Theresa R
Published in Future cardiology (01.09.2015)
Published in Future cardiology (01.09.2015)
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Journal Article
Design, Synthesis and Potential Utility of Fluorescence Probes that Target DFG-out Conformation of p38α for High Throughput Screening Binding Assay
Tecle, Haile, Feru, Frederic, Liu, Hu, Kuhn, Cyrille, Rennie, Glen, Morris, Mark, Shao, Jiangxing, Cheng, Alan C, Gikunju, Diana, Miret, Juan, Coli, Rocco, Xi, Simon (Hualin), Clugston, Susan L, Low, Simon, Kazmirski, Steven, Ding, Yuan-Hua, Cao, Qing, Johnson, Theresa L, Deshmukh, Gayatri D, DiNitto, Jonathan P, Wu, Joe C, English, Jessie M
Published in Chemical biology & drug design (01.12.2009)
Published in Chemical biology & drug design (01.12.2009)
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Journal Article
Making the right choice
Johnson, Theresa
Published in Community practitioner : the journal of the Community Practitioners' & Health Visitors' Association (01.07.2017)
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Published in Community practitioner : the journal of the Community Practitioners' & Health Visitors' Association (01.07.2017)
Journal Article
Ability of Bruton's Tyrosine Kinase Inhibitors to Sequester Y551 and Prevent Phosphorylation Determines Potency for Inhibition of Fc Receptor but not B-Cell Receptor Signaling
Bender, Andrew T, Gardberg, Anna, Pereira, Albertina, Johnson, Theresa, Wu, Yin, Grenningloh, Roland, Head, Jared, Morandi, Federica, Haselmayer, Philipp, Liu-Bujalski, Lesley
Published in Molecular pharmacology (01.03.2017)
Published in Molecular pharmacology (01.03.2017)
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Journal Article
Structure−Activity Relationships of the Antimalarial Agent Artemisinin. 5. Analogs of 10-Deoxoartemisinin Substituted at C-3 and C-9
Avery, Mitchell A, Mehrotra, Sanjiv, Johnson, Theresa L, Bonk, Jason D, Vroman, Jeffrey A, Miller, Robert
Published in Journal of medicinal chemistry (11.10.1996)
Published in Journal of medicinal chemistry (11.10.1996)
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Journal Article
Large-Scale Assessment of Binding Free Energy Calculations in Active Drug Discovery Projects
Schindler, Christina E. M, Baumann, Hannah, Blum, Andreas, Böse, Dietrich, Buchstaller, Hans-Peter, Burgdorf, Lars, Cappel, Daniel, Chekler, Eugene, Czodrowski, Paul, Dorsch, Dieter, Eguida, Merveille K. I, Follows, Bruce, Fuchß, Thomas, Grädler, Ulrich, Gunera, Jakub, Johnson, Theresa, Jorand Lebrun, Catherine, Karra, Srinivasa, Klein, Markus, Knehans, Tim, Koetzner, Lisa, Krier, Mireille, Leiendecker, Matthias, Leuthner, Birgitta, Li, Liwei, Mochalkin, Igor, Musil, Djordje, Neagu, Constantin, Rippmann, Friedrich, Schiemann, Kai, Schulz, Robert, Steinbrecher, Thomas, Tanzer, Eva-Maria, Unzue Lopez, Andrea, Viacava Follis, Ariele, Wegener, Ansgar, Kuhn, Daniel
Published in Journal of chemical information and modeling (23.11.2020)
Published in Journal of chemical information and modeling (23.11.2020)
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