HIF Transcription Factors, Inflammation, and Immunity
Palazon, Asis, Goldrath, Ananda W., Nizet, Victor, Johnson, Randall S.
Published in Immunity (Cambridge, Mass.) (16.10.2014)
Published in Immunity (Cambridge, Mass.) (16.10.2014)
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HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression
Keith, Brian, Johnson, Randall S., Simon, M. Celeste
Published in Nature reviews. Cancer (01.01.2012)
Published in Nature reviews. Cancer (01.01.2012)
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Regulation of Glycolysis by Pdk Functions as a Metabolic Checkpoint for Cell Cycle Quiescence in Hematopoietic Stem Cells
Takubo, Keiyo, Nagamatsu, Go, Kobayashi, Chiharu I., Nakamura-Ishizu, Ayako, Kobayashi, Hiroshi, Ikeda, Eiji, Goda, Nobuhito, Rahimi, Yasmeen, Johnson, Randall S., Soga, Tomoyoshi, Hirao, Atsushi, Suematsu, Makoto, Suda, Toshio
Published in Cell stem cell (03.01.2013)
Published in Cell stem cell (03.01.2013)
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Increased adipocyte O2 consumption triggers HIF-1α, causing inflammation and insulin resistance in obesity
Lee, Yun Sok, Kim, Jung-Whan, Osborne, Olivia, Oh, Da Young, Sasik, Roman, Schenk, Simon, Chen, Ai, Chung, Heekyung, Murphy, Anne, Watkins, Steven M, Quehenberger, Oswald, Johnson, Randall S, Olefsky, Jerrold M
Published in Cell (05.06.2014)
Published in Cell (05.06.2014)
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Constitutive Glycolytic Metabolism Supports CD8+ T Cell Effector Memory Differentiation during Viral Infection
Phan, Anthony T., Doedens, Andrew L., Palazon, Asis, Tyrakis, Petros A., Cheung, Kitty P., Johnson, Randall S., Goldrath, Ananda W.
Published in Immunity (Cambridge, Mass.) (15.11.2016)
Published in Immunity (Cambridge, Mass.) (15.11.2016)
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Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging
Ho, Ya-Hsuan, del Toro, Raquel, Rivera-Torres, José, Rak, Justyna, Korn, Claudia, García-García, Andrés, Macías, David, González-Gómez, Cristina, del Monte, Alberto, Wittner, Monika, Waller, Amie K., Foster, Holly R., López-Otín, Carlos, Johnson, Randall S., Nerlov, Claus, Ghevaert, Cedric, Vainchenker, William, Louache, Fawzia, Andrés, Vicente, Méndez-Ferrer, Simón
Published in Cell stem cell (05.09.2019)
Published in Cell stem cell (05.09.2019)
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Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells
Takubo, Keiyo, Goda, Nobuhito, Yamada, Wakako, Iriuchishima, Hirono, Ikeda, Eiji, Kubota, Yoshiaki, Shima, Haruko, Johnson, Randall S., Hirao, Atsushi, Suematsu, Makoto, Suda, Toshio
Published in Cell stem cell (03.09.2010)
Published in Cell stem cell (03.09.2010)
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An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression
Palazon, Asis, Tyrakis, Petros A., Macias, David, Veliça, Pedro, Rundqvist, Helene, Fitzpatrick, Susan, Vojnovic, Nikola, Phan, Anthony T., Loman, Niklas, Hedenfalk, Ingrid, Hatschek, Thomas, Lövrot, John, Foukakis, Theodoros, Goldrath, Ananda W., Bergh, Jonas, Johnson, Randall S.
Published in Cancer cell (13.11.2017)
Published in Cancer cell (13.11.2017)
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Astrocyte-derived vascular endothelial growth factor stabilizes vessels in the developing retinal vasculature
Scott, Andrew, Powner, Michael B, Gandhi, Pranita, Clarkin, Claire, Gutmann, David H, Johnson, Randall S, Ferrara, Napoleone, Fruttiger, Marcus
Published in PloS one (29.07.2010)
Published in PloS one (29.07.2010)
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Cytotoxic T-cells mediate exercise-induced reductions in tumor growth
Rundqvist, Helene, Veliça, Pedro, Barbieri, Laura, Gameiro, Paulo A, Bargiela, David, Gojkovic, Milos, Mijwel, Sara, Reitzner, Stefan Markus, Wulliman, David, Ahlstedt, Emil, Ule, Jernej, Östman, Arne, Johnson, Randall S
Published in eLife (23.10.2020)
Published in eLife (23.10.2020)
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Endothelial Cell HIF-1α and HIF-2α Differentially Regulate Metastatic Success
Branco-Price, Cristina, Zhang, Na, Schnelle, Moritz, Evans, Colin, Katschinski, Dörthe M., Liao, Debbie, Ellies, Lesley, Johnson, Randall S.
Published in Cancer cell (17.01.2012)
Published in Cancer cell (17.01.2012)
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APOL1 Genetic Variants in Focal Segmental Glomerulosclerosis and HIV-Associated Nephropathy
KOPP, Jeffrey B, NELSON, George W, MOKRZYCKI, Michele H, KIMMEL, Paul L, LIMOU, Sophie, AHUJA, Tejinder S, BERNS, Jeffrey S, FRYC, Justyna, SIMON, Eric E, SMITH, Michael C, TRACHTMAN, Howard, MICHEL, Donna M, SAMPATH, Karmini, SCHELLING, Jeffrey R, VLAHOV, David, POLLAK, Martin, WINKLER, Cheryl A, JOHNSON, Randall C, GENOVESE, Giulio, PING AN, FRIEDMAN, David, BRIGGS, William, DART, Richard, KORBET, Stephen
Published in Journal of the American Society of Nephrology (01.11.2011)
Published in Journal of the American Society of Nephrology (01.11.2011)
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NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α
Rius, Jordi, Guma, Monica, Schachtrup, Christian, Akassoglou, Katerina, Zinkernagel, Annelies S., Nizet, Victor, Johnson, Randall S., Haddad, Gabriel G., Karin, Michael
Published in Nature (London) (05.06.2008)
Published in Nature (London) (05.06.2008)
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Hypoxia-inducible factors enhance the effector responses of CD8+ T cells to persistent antigen
Doedens, Andrew L, Phan, Anthony T, Stradner, Martin H, Fujimoto, Jessica K, Nguyen, Jessica V, Yang, Edward, Johnson, Randall S, Goldrath, Ananda W
Published in Nature immunology (01.11.2013)
Published in Nature immunology (01.11.2013)
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Journal Article
HIF-1α-PDK1 axis-induced active glycolysis plays an essential role in macrophage migratory capacity
Semba, Hiroaki, Takeda, Norihiko, Isagawa, Takayuki, Sugiura, Yuki, Honda, Kurara, Wake, Masaki, Miyazawa, Hidenobu, Yamaguchi, Yoshifumi, Miura, Masayuki, Jenkins, Dana M. R., Choi, Hyunsung, Kim, Jung-whan, Asagiri, Masataka, Cowburn, Andrew S., Abe, Hajime, Soma, Katsura, Koyama, Katsuhiro, Katoh, Manami, Sayama, Keimon, Goda, Nobuhito, Johnson, Randall S., Manabe, Ichiro, Nagai, Ryozo, Komuro, Issei
Published in Nature communications (18.05.2016)
Published in Nature communications (18.05.2016)
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