Interleukin-36 (IL-36) Ligands Require Processing for Full Agonist (IL-36α, IL-36β, and IL-36γ) or Antagonist (IL-36Ra) Activity
Towne, Jennifer E., Renshaw, Blair R., Douangpanya, Jason, Lipsky, Brian P., Shen, Min, Gabel, Christopher A., Sims, John E.
Published in The Journal of biological chemistry (09.12.2011)
Published in The Journal of biological chemistry (09.12.2011)
Get full text
Journal Article
IL-1RL2 and its ligands contribute to the cytokine network in psoriasis
Blumberg, Hal, Dinh, Huyen, Dean, Jr, Charles, Trueblood, Esther S, Bailey, Keith, Shows, Donna, Bhagavathula, Narasimharao, Aslam, Muhammad Nadeem, Varani, James, Towne, Jennifer E, Sims, John E
Published in The Journal of immunology (1950) (01.10.2010)
Published in The Journal of immunology (1950) (01.10.2010)
Get full text
Journal Article
Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation
Blumberg, Hal, Dinh, Huyen, Trueblood, Esther S, Pretorius, James, Kugler, David, Weng, Ning, Kanaly, Suzanne T, Towne, Jennifer E, Willis, Cynthia R, Kuechle, Melanie K, Sims, John E, Peschon, Jacques J
Published in The Journal of experimental medicine (29.10.2007)
Published in The Journal of experimental medicine (29.10.2007)
Get full text
Journal Article
SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling
Li, Xiaoxia, Wald, David, Qin, Jinzhong, Zhao, Zhendong, Qian, Youcun, Naramura, Mayumi, Tian, Liping, Towne, Jennifer, Sims, John E, Stark, George R
Published in Nature immunology (01.09.2003)
Published in Nature immunology (01.09.2003)
Get full text
Journal Article
A novel mutation of IL1RN in the deficiency of interleukin‐1 receptor antagonist syndrome: Description of two unrelated cases from Brazil
Jesus, Adriana A., Osman, Mazen, Silva, Clovis A., Kim, Peter W., Pham, Tuyet‐Hang, Gadina, Massimo, Yang, Barbara, Bertola, Débora R., Carneiro‐Sampaio, Magda, Ferguson, Polly J., Renshaw, Blair R., Schooley, Ken, Brown, Michael, Al‐Dosari, Asma, Al‐Alami, Jamil, Sims, John E., Goldbach‐Mansky, Raphaela, El‐Shanti, Hatem
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.12.2011)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.12.2011)
Get full text
Journal Article
A Central Nervous System-Restricted Isoform of the Interleukin-1 Receptor Accessory Protein Modulates Neuronal Responses to Interleukin-1
Smith, Dirk E., Lipsky, Brian P., Russell, Chris, Ketchem, Randal R., Kirchner, Jacqueline, Hensley, Kelly, Huang, Yangyang, Friedman, Wilma J., Boissonneault, Vincent, Plante, Marie-Michèle, Rivest, Serge, Sims, John E.
Published in Immunity (Cambridge, Mass.) (19.06.2009)
Published in Immunity (Cambridge, Mass.) (19.06.2009)
Get full text
Journal Article
Externalization of the Leaderless Cytokine IL-1F6 Occurs in Response to Lipopolysaccharide/ATP Activation of Transduced Bone Marrow Macrophages
Martin, Unja, Scholler, John, Gurgel, Jesse, Renshaw, Blair, Sims, John E, Gabel, Christopher A
Published in The Journal of immunology (1950) (15.09.2009)
Published in The Journal of immunology (1950) (15.09.2009)
Get full text
Journal Article
The Soluble Form of IL-1 Receptor Accessory Protein Enhances the Ability of Soluble Type II IL-1 Receptor to Inhibit IL-1 Action
Smith, Dirk E., Hanna, Roberta, Della Friend, Moore, Heather, Chen, Hongbo, Farese, Ann M., MacVittie, Thomas J., Virca, G.Duke, Sims, John E.
Published in Immunity (Cambridge, Mass.) (2003)
Published in Immunity (Cambridge, Mass.) (2003)
Get full text
Journal Article
IL-36R ligands are potent regulators of dendritic and T cells
Vigne, Solenne, Palmer, Gaby, Lamacchia, Céline, Martin, Praxedis, Talabot-Ayer, Dominique, Rodriguez, Emiliana, Ronchi, Francesca, Sallusto, Federica, Dinh, Huyen, Sims, John E., Gabay, Cem
Published in Blood (24.11.2011)
Published in Blood (24.11.2011)
Get full text
Journal Article
IL-36 signaling amplifies Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells
Vigne, Solenne, Palmer, Gaby, Martin, Praxedis, Lamacchia, Céline, Strebel, Deborah, Rodriguez, Emiliana, Olleros, Maria L., Vesin, Dominique, Garcia, Irene, Ronchi, Francesca, Sallusto, Federica, Sims, John E., Gabay, Cem
Published in Blood (25.10.2012)
Published in Blood (25.10.2012)
Get full text
Journal Article
Interleukin-36–Receptor Antagonist Deficiency and Generalized Pustular Psoriasis
Marrakchi, Slaheddine, Guigue, Philippe, Renshaw, Blair R, Puel, Anne, Pei, Xue-Yuan, Fraitag, Sylvie, Zribi, Jihen, Bal, Elodie, Cluzeau, Céline, Chrabieh, Maya, Towne, Jennifer E, Douangpanya, Jason, Pons, Christian, Mansour, Sourour, Serre, Valérie, Makni, Hafedh, Mahfoudh, Nadia, Fakhfakh, Faiza, Bodemer, Christine, Feingold, Josué, Hadj-Rabia, Smail, Favre, Michel, Genin, Emmanuelle, Sahbatou, Mourad, Munnich, Arnold, Casanova, Jean-Laurent, Sims, John E, Turki, Hamida, Bachelez, Hervé, Smahi, Asma
Published in The New England journal of medicine (18.08.2011)
Published in The New England journal of medicine (18.08.2011)
Get full text
Journal Article
Essential pathogenic role of endogenous IL‐18 in murine diabetes induced by multiple low doses of streptozotocin. Prevention of hyperglycemia and insulitis by a recombinant IL‐18‐binding protein: Fc construct
Nicoletti, Ferdinando, Marco, Roberto Di, Papaccio, Gianpaolo, Conget, Ignacio, Gomis, Ramon, Bernardini, Renato, Sims, John E., Shoenfeld, Yehuda, Bendtzen, Klaus
Published in European journal of immunology (01.08.2003)
Published in European journal of immunology (01.08.2003)
Get full text
Journal Article
Purification, Cloning, and Characterization of Nek8, a Novel NIMA-related Kinase, and Its Candidate Substrate Bicd2
Holland, Pamela M., Milne, Alison, Garka, Kirsten, Johnson, Richard S., Willis, Cynthia, Sims, John E., Rauch, Charles T., Bird, Timothy A., Virca, G. Duke
Published in The Journal of biological chemistry (03.05.2002)
Published in The Journal of biological chemistry (03.05.2002)
Get full text
Journal Article
Novel protein therapeutic joint retention strategy based on collagen‐binding Avimers
Hulme, Joanne T., D'Souza, Warren N., McBride, Helen J., Yoon, Bo‐Rin Park, Willee, Angela M., Duguay, Amy, Thomas, Melissa, Fan, Bin, Dayao, Maria Rosalyn, Rottman, James B., Merriam, Kim, Xie, Jiansong, Smith, Richard, Alba, Benjamin M., Case, Ryan B., Dang, Khue, Montalvan, Anielka, Grinberg, Natalia, Sun, Hong, Black, Roy A., Gabel, Christopher A., Sims, John E., Moore, Kevin, Bakker, Alice, Li, Peng
Published in Journal of orthopaedic research (01.04.2018)
Published in Journal of orthopaedic research (01.04.2018)
Get full text
Journal Article
Mal (MyD88-adapter-like) is required for Toll-like receptor-4 signal transduction
O'Neill, Luke A. J, Fitzgerald, Katherine A, Palsson-McDermott, Eva M, Bowie, Andrew G, Jefferies, Caroline A, Mansell, Ashley S, Brady, Gareth, Brint, Elizabeth, Dunne, Aisling, Gray, Pearl, Harte, Mary T, McMurray, Diane, Smith, Dirk E, Sims, John E, Bird, Timothy A
Published in Nature (London) (06.09.2001)
Published in Nature (London) (06.09.2001)
Get full text
Journal Article
cDNA Expression Cloning of the IL-1 Receptor, a Member of the Immunoglobulin Superfamily
Sims, John E., March, Carl J., Cosman, David, Widmer, Michael B., MacDonald, H. Robson, McMahan, Catherine J., Grubin, Catherine E., Wignall, Janis M., Jackson, Jana L., Call, Susan M., Friend, Della, Alpert, Alan R., Gillis, Steven, Urdal, David L., Dower, Steven K.
Published in Science (American Association for the Advancement of Science) (29.07.1988)
Published in Science (American Association for the Advancement of Science) (29.07.1988)
Get full text
Journal Article