Efficacy of TG101348, a Selective JAK2 Inhibitor, in Treatment of a Murine Model of JAK2V617F-Induced Polycythemia Vera
Wernig, Gerlinde, Kharas, Michael G., Okabe, Rachel, Moore, Sandra A., Leeman, Dena S., Cullen, Dana E., Gozo, Maricel, McDowell, Elizabeth P., Levine, Ross L., Doukas, John, Mak, Chi Ching, Noronha, Glenn, Martin, Michael, Ko, Yon D., Lee, Benjamin H., Soll, Richard M., Tefferi, Ayalew, Hood, John D., Gilliland, D. Gary
Published in Cancer cell (01.04.2008)
Published in Cancer cell (01.04.2008)
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Tumor Regression by Targeted Gene Delivery to the Neovasculature
Hood, John D., Bednarski, Mark, Frausto, Ricardo, Guccione, Samira, Reisfeld, Ralph A., Xiang, Rong, Cheresh, David A.
Published in Science (American Association for the Advancement of Science) (28.06.2002)
Published in Science (American Association for the Advancement of Science) (28.06.2002)
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Development of Prodrug 4-Chloro-3-(5-methyl-3-{[4-(2-pyrrolidin-1-ylethoxy)phenyl]amino}-1,2,4-benzotriazin-7-yl)phenyl Benzoate (TG100801): A Topically Administered Therapeutic Candidate in Clinical Trials for the Treatment of Age-Related Macular Degeneration
Palanki, Moorthy S. S, Akiyama, Hideo, Campochiaro, Peter, Cao, Jianguo, Chow, Chun P, Dellamary, Luis, Doukas, John, Fine, Richard, Gritzen, Colleen, Hood, John D, Hu, Steven, Kachi, Shu, Kang, Xinshan, Klebansky, Boris, Kousba, Ahmed, Lohse, Dan, Mak, Chi Ching, Martin, Michael, McPherson, Andrew, Pathak, Ved P, Renick, Joel, Soll, Richard, Umeda, Naoyasu, Yee, Shiyin, Yokoi, Katsutoshi, Zeng, Binqi, Zhu, Hong, Noronha, Glenn
Published in Journal of medicinal chemistry (27.03.2008)
Published in Journal of medicinal chemistry (27.03.2008)
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Journal Article
Building a Better Trap
Hood, John D., Cheresh, David A.
Published in Proceedings of the National Academy of Sciences - PNAS (22.07.2003)
Published in Proceedings of the National Academy of Sciences - PNAS (22.07.2003)
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Decreased differentiation of erythroid cells exacerbates ineffective erythropoiesis in β-thalassemia
Libani, Ilaria V., Guy, Ella C., Melchiori, Luca, Schiro, Raffaella, Ramos, Pedro, Breda, Laura, Scholzen, Thomas, Chadburn, Amy, Liu, YiFang, Kernbach, Margrit, Baron-Lühr, Bettina, Porotto, Matteo, de Sousa, Maria, Rachmilewitz, Eliezer A., Hood, John D., Cappellini, M. Domenica, Giardina, Patricia J., Grady, Robert W., Gerdes, Johannes, Rivella, Stefano
Published in Blood (01.08.2008)
Published in Blood (01.08.2008)
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Journal Article
Selective Inhibition of JAK2-Driven Erythroid Differentiation of Polycythemia Vera Progenitors
Geron, Ifat, Abrahamsson, Annelie E., Barroga, Charlene F., Kavalerchik, Edward, Gotlib, Jason, Hood, John D., Durocher, Jeffrey, Mak, Chi Ching, Noronha, Glenn, Soll, Richard M., Tefferi, Ayalew, Kaushansky, Ken, Jamieson, Catriona H.M.
Published in Cancer cell (01.04.2008)
Published in Cancer cell (01.04.2008)
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Journal Article
Selective Requirement for Src Kinases during VEGF-Induced Angiogenesis and Vascular Permeability
Eliceiri, Brian P, Paul, Robert, Schwartzberg, Pamela L, Hood, John D, Leng, Jie, Cheresh, David A
Published in Molecular cell (01.12.1999)
Published in Molecular cell (01.12.1999)
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Nitric Oxide Is an Upstream Signal of Vascular Endothelial Growth Factor-induced Extracellular Signal-regulated Kinase½ Activation in Postcapillary Endothelium
Parenti, Astrid, Morbidelli, Lucia, Cui, Xiao-Lan, Douglas, Janice G., Hood, John D., Granger, Harris J., Ledda, Fabrizio, Ziche, Marina
Published in The Journal of biological chemistry (13.02.1998)
Published in The Journal of biological chemistry (13.02.1998)
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Journal Article
Discovery of [7-(2,6-dichlorophenyl)-5-methylbenzo [1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-ylethoxy)phenyl]amine—a potent, orally active Src kinase inhibitor with anti-tumor activity in preclinical assays
Noronha, Glenn, Barrett, Kathy, Boccia, Antonio, Brodhag, Tessa, Cao, Jianguo, Chow, Chun P., Dneprovskaia, Elena, Doukas, John, Fine, Richard, Gong, Xianchang, Gritzen, Colleen, Gu, Hong, Hanna, Ehab, Hood, John D., Hu, Steven, Kang, Xinshan, Key, Jann, Klebansky, Boris, Kousba, Ahmed, Li, Ge, Lohse, Dan, Mak, Chi Ching, McPherson, Andrew, Palanki, Moorthy S.S., Pathak, Ved P., Renick, Joel, Shi, Feng, Soll, Richard, Splittgerber, Ute, Stoughton, Silva, Tang, Suhan, Yee, Shiyin, Zeng, Binqi, Zhao, Ningning, Zhu, Hong
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
Published in Bioorganic & medicinal chemistry letters (01.02.2007)
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Journal Article
Src-Mediated Coupling of Focal Adhesion Kinase to Integrin αvβ5 in Vascular Endothelial Growth Factor Signaling
Eliceiri, Brian P., Puente, Xose X., Hood, John D., Stupack, Dwayne G., Schlaepfer, David D., Huang, Xiaozhu Z., Sheppard, Dean, Cheresh, David A.
Published in The Journal of cell biology (01.04.2002)
Published in The Journal of cell biology (01.04.2002)
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Journal Article
Src-mediated coupling of focal adhesion kinase to integrin α v β 5 in vascular endothelial growth factor signaling
Eliceiri, Brian P., Puente, Xose S., Hood, John D., Stupack, Dwayne G., Schlaepfer, David D., Huang, Xiaozhu Z., Sheppard, Dean, Cheresh, David A.
Published in The Journal of cell biology (01.04.2002)
Published in The Journal of cell biology (01.04.2002)
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Journal Article
Prospective Identification of Resistance Mutants to the JAK2 Inhibitor TG101348
Hood, John D., Alomia, Marcela, Cao, Jon, Chow, Chun, Ehab, Hanna, Dan, Lohse, Ching, Mak Chi, Andy, McPherson, Glenn, Noronha, Betty, Tam, Hong, Zhu, Soll, Richard
Published in Blood (16.11.2007)
Published in Blood (16.11.2007)
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Journal Article
Selective Inhibition of JAK2-Driven Erythroid Differentiation of Polycythemia Vera Progenitors
Geron, Ifat, Abrahamsson, Annelie E., Barroga, Charlene F., Kavalerchik, Edward, Gotlib, Jason, Hood, John D., Durocher, Jeffrey, Mak, Chi Ching, Noronha, Glenn, Soll, Richard M., Tefferi, Ayalew, Kaushansky, Ken, Jamieson, Catriona H.M.
Published in Cancer cell (06.05.2008)
Published in Cancer cell (06.05.2008)
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