Streptolysin O Rapidly Impairs Neutrophil Oxidative Burst and Antibacterial Responses to Group A Streptococcus
Uchiyama, Satoshi, Döhrmann, Simon, Timmer, Anjuli M, Dixit, Neha, Ghochani, Mariam, Bhandari, Tamara, Timmer, John C, Sprague, Kimberly, Bubeck-Wardenburg, Juliane, Simon, Scott I, Nizet, Victor
Published in Frontiers in immunology (16.11.2015)
Published in Frontiers in immunology (16.11.2015)
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Journal Article
Streptolysin O Promotes Group A Streptococcus Immune Evasion by Accelerated Macrophage Apoptosis
Timmer, Anjuli M., Timmer, John C., Pence, Morgan A., Hsu, Li-Chung, Ghochani, Mariam, Frey, Terrence G., Karin, Michael, Salvesen, Guy S., Nizet, Victor
Published in The Journal of biological chemistry (09.01.2009)
Published in The Journal of biological chemistry (09.01.2009)
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Journal Article
Structural and kinetic determinants of protease substrates
Snipas, Scott J, Salvesen, Guy S, Regan, Tim, Timmer, John C, Eroshkin, Alexey M, Pop, Cristina, Zhu, Wenhong, Riedl, Stefan J
Published in Nature structural & molecular biology (01.10.2009)
Published in Nature structural & molecular biology (01.10.2009)
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Journal Article
Profiling constitutive proteolytic events in vivo
Timmer, John C, Enoksson, Mari, Wildfang, Eric, Zhu, Wenhong, Igarashi, Yoshinobu, Denault, Jean-Benard, Ma, Yuliang, Dummitt, Benjamin, Chang, Yie-Hwa, Mast, Alan E, Eroshkin, Alexey, Smith, Jeffrey W, Tao, W Andy, Salvesen, Guy S
Published in Biochemical journal (01.10.2007)
Published in Biochemical journal (01.10.2007)
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Journal Article
INBRX-120, a CD8α-targeted detuned IL-2 that selectively expands and activates tumoricidal effector cells for safe and durable in vivo responses
Sulzmaier, Florian J, Kern, Nadja, Ahn, Sae Jeong, Polovina, Anya, Ho, Jason, Hussain, Abrahim, Cyprus, Garrett, Macedo, Chelsie, Pandit, Rajay, Crago, William, Rowell, Emily, Timmer, John C, Eckelman, Brendan P
Published in Journal for immunotherapy of cancer (01.01.2023)
Published in Journal for immunotherapy of cancer (01.01.2023)
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Journal Article
Identification of Proteolytic Cleavage Sites by Quantitative Proteomics
Enoksson, Mari, Li, Jingwei, Ivancic, Melanie M, Timmer, John C, Wildfang, Eric, Eroshkin, Alexey, Salvesen, Guy S, Tao, W. Andy
Published in Journal of proteome research (01.07.2007)
Published in Journal of proteome research (01.07.2007)
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Journal Article
OX40-BINDING POLYPEPTIDES AND USES THEREOF
BRYAN BECKLUND, WILLIAM CRAGO, KYLE JONES, FLORIAN SULZMAIER, KATELYN WILLIS, BRENDAN P ECKELMAN, JOHN C TIMMER
Year of Publication 04.06.2024
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Year of Publication 04.06.2024
Patent
MULTISPECIFIC POLYPEPTIDE CONSTRUCTS HAVING CONSTRAINED CD3 BINDING AND METHODS OF USING THE SAME
MICHAEL D KAPLAN, KATELYN M WILLIS, BRENDAN P ECKELMAN, QUINN DEVERAUX, JOHN C TIMMER
Year of Publication 10.05.2024
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Year of Publication 10.05.2024
Patent
SERPIN FUSION POLYPEPTIDES AND METHODS OF USE THEREOF
GRANT B GUENTHER, PETER L NGUY, BRENDAN P ECKELMAN, QUINN DEVERAUX, JOHN C TIMMER
Year of Publication 28.05.2020
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Year of Publication 28.05.2020
Patent
MULTIVALENT AND MULTISPECIFIC DR5-BINDING FUSION PROTEINS
HUSSAIN ABRAHIM, AMIR S RAZAI, KYLE S JONES, KATELYN M WILLIS, QUINN DEVERAUX, BRENDAN P ECKELMAN, JOHN C TIMMER
Year of Publication 25.03.2021
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Year of Publication 25.03.2021
Patent
N-terminomics: a high-content screen for protease substrates and their cleavage sites
Timmer, John C, Salvesen, Guy S
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2011)
Published in Methods in molecular biology (Clifton, N.J.) (01.01.2011)
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Journal Article
SERPIN FUSION POLYPEPTIDE AND METHOD FOR USING THE SAME
GRANT B GUENTHER, PETER L NGUY, BRENDAN P ECKELMAN, QUINN DEVERAUX, JOHN C TIMMER
Year of Publication 18.01.2018
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Year of Publication 18.01.2018
Patent
Abstract 613: Development of FPA154, a novel tetravalent anti-GITR antibody, for the treatment of solid tumors
Barbee, Susannah D., Chen, Amanda, Johnson, Susan, Bellovin, David I., Timmer, John C., Wondyfraw, Nebiyu, Mkrtichyan, Mikayel, Razai, Amir S., Jones, Kyle S., Hata, Chelsie Y., Gonzalez, Denise, Deveraux, Quinn, Eckelman, Brendan P., Borges, Luis
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Type iii secretion system targeting molecules
Timmer, John C, Eckelman, Brendan P, Deveraux, Quinn, Hollands, Andrew
Year of Publication 30.08.2024
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Year of Publication 30.08.2024
Patent
CLEC12a binding polypeptides and uses thereof
Timmer, John C, Rascon, Lucas, Eckelman, Brendan P, Sanabria, Angelica
Year of Publication 23.07.2024
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Year of Publication 23.07.2024
Patent