screen of chemical modifications identifies position-specific modification by UNA to most potently reduce siRNA off-target effects
Bramsen, Jesper B, Pakula, Malgorzata M, Hansen, Thomas B, Bus, Claus, Langkjær, Niels, Odadzic, Dalibor, Smicius, Romualdas, Wengel, Suzy L, Chattopadhyaya, Jyoti, Engels, Joachim W, Herdewijn, Piet, Wengel, Jesper, Kjems, Jørgen
Published in Nucleic acids research (01.09.2010)
Published in Nucleic acids research (01.09.2010)
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Journal Article
Selective Uncaging of DNA through Reaction Rate Selectivity
Rodrigues-Correia, Alexandre, Knapp-Bühle, Diana, Engels, Joachim W, Heckel, Alexander
Published in Organic letters (03.10.2014)
Published in Organic letters (03.10.2014)
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Journal Article
Base-specific spin-labeling of RNA for structure determination
Piton, Nelly, Mu, Yuguang, Stock, Gerhard, Prisner, Thomas F, Schiemann, Olav, Engels, Joachim W
Published in Nucleic acids research (01.05.2007)
Published in Nucleic acids research (01.05.2007)
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Journal Article
ribosome assembly factor Nep1 responsible for Bowen-Conradi syndrome is a pseudouridine-N1-specific methyltransferase
Wurm, Jan Philip, Meyer, Britta, Bahr, Ute, Held, Martin, Frolow, Olga, Kötter, Peter, Engels, Joachim W, Heckel, Alexander, Karas, Michael, Entian, Karl-Dieter, Wöhnert, Jens
Published in Nucleic acids research (01.04.2010)
Published in Nucleic acids research (01.04.2010)
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Journal Article
large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity
Bramsen, Jesper B, Laursen, Maria B, Nielsen, Anne F, Hansen, Thomas B, Bus, Claus, Langkjær, Niels, Babu, B. Ravindra, Højland, Torben, Abramov, Mikhail, Van Aerschot, Arthur, Odadzic, Dalibor, Smicius, Romualdas, Haas, Jens, Andree, Cordula, Barman, Jharna, Wenska, Malgorzata, Srivastava, Puneet, Zhou, Chuanzheng, Honcharenko, Dmytro, Hess, Simone, Müller, Elke, Bobkov, Georgii V, Mikhailov, Sergey N, Fava, Eugenio, Meyer, Thomas F, Chattopadhyaya, Jyoti, Zerial, Marino, Engels, Joachim W, Herdewijn, Piet, Wengel, Jesper, Kjems, Jørgen
Published in Nucleic acids research (01.05.2009)
Published in Nucleic acids research (01.05.2009)
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Journal Article
Design, Synthesis, and Antiviral Activity of Novel Ribonucleosides of 1,2,3-Triazolylbenzyl-aminophosphonates
Ouahrouch, Abdelaaziz, Taourirte, Moha, Schols, Dominique, Snoeck, Robert, Andrei, Graciela, Engels, Joachim W., Lazrek, Hassan B.
Published in Archiv der Pharmazie (Weinheim) (01.01.2016)
Published in Archiv der Pharmazie (Weinheim) (01.01.2016)
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Journal Article
Spin labeling of oligonucleotides with the nitroxide TPA and use of PELDOR, a pulse EPR method, to measure intramolecular distances
Schiemann, Olav, Engels, Joachim W, Piton, Nelly, Plackmeyer, Jörn, Bode, Bela E, Prisner, Thomas F
Published in Nature protocols (01.04.2007)
Published in Nature protocols (01.04.2007)
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Journal Article
Three-State Fluorescence of a 2‑Functionalized Pyrene-Based RNA Label
Reuss, Andreas J, Grünewald, Christian, Gustmann, Henrik, Engels, Joachim W, Wachtveitl, Josef
Published in The journal of physical chemistry. B (13.04.2017)
Published in The journal of physical chemistry. B (13.04.2017)
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Journal Article
Inhibition of replication of hepatitis B virus in transgenic mice following administration of hepatotropic lipoplexes containing guanidinopropyl-modified siRNAs
Marimani, Musa D., Ely, Abdullah, Buff, Maximilian C.R., Bernhardt, Stefan, Engels, Joachim W., Scherman, Daniel, Escriou, Virginie, Arbuthnot, Patrick
Published in Journal of controlled release (10.07.2015)
Published in Journal of controlled release (10.07.2015)
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Journal Article
Benzimidazole-1,2,3-triazole Hybrid Molecules: Synthesis and Evaluation for Antibacterial/Antifungal Activity
Ouahrouch, Abdelaaziz, Ighachane, Hana, Taourirte, Moha, Engels, Joachim W., Sedra, My Hassan, Lazrek, Hassan B.
Published in Archiv der Pharmazie (Weinheim) (01.10.2014)
Published in Archiv der Pharmazie (Weinheim) (01.10.2014)
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Journal Article
Microwave-Assisted Click Chemistry for Nucleoside Functionalization: Useful Derivatives for Analytical and Biological Applications
Krim, Jamal, Taourirte, Moha, Gruenewald, Christian, Krstic, Ivan, Engels, Joachim W.
Published in Synthesis (Stuttgart) (01.02.2013)
Published in Synthesis (Stuttgart) (01.02.2013)
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