HLA-DR7 and HLA-DQ2: Transgenic mouse strains tested as a model system for ximelagatran hepatotoxicity
Lundgren, Hanna, Martinsson, Klara, Cederbrant, Karin, Jirholt, Johan, Mucs, Daniel, Madeyski-Bengtson, Katja, Havarinasab, Said, Hultman, Per
Published in PloS one (21.09.2017)
Published in PloS one (21.09.2017)
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4-aminobutyrate aminotransferase (ABAT): genetic and pharmacological evidence for an involvement in gastro esophageal reflux disease
Jirholt, Johan, Asling, Bengt, Hammond, Paul, Davidson, Geoffrey, Knutsson, Mikael, Walentinsson, Anna, Jensen, Jörgen M, Lehmann, Anders, Agreus, Lars, Lagerström-Fermer, Maria
Published in PloS one (28.04.2011)
Published in PloS one (28.04.2011)
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Identification of susceptibility genes for experimental autoimmune encephalomyelitis that overcome the effect of protective alleles at the eae2 locus
Jirholt, Johan, Lindqvist, Anna-Karin, Karlsson, Jenny, Andersson, Åsa, Holmdahl, Rikard
Published in International immunology (01.01.2002)
Published in International immunology (01.01.2002)
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AZD0284, a Potent, Selective, and Orally Bioavailable Inverse Agonist of Retinoic Acid Receptor-Related Orphan Receptor C2
Narjes, Frank, Llinas, Antonio, von Berg, Stefan, Jirholt, Johan, Lever, Sarah, Pehrson, Rikard, Collins, Mia, Malmberg, Anna, Svanberg, Petter, Xue, Yafeng, Olsson, Roine I, Malmberg, Jesper, Hughes, Glyn, Hossain, Nafizal, Grindebacke, Hanna, Leffler, Agnes, Krutrök, Nina, Bäck, Elisabeth, Ramnegård, Marie, Lepistö, Matti, Thunberg, Linda, Aagaard, Anna, McPheat, Jane, Hansson, Eva L, Chen, Rongfeng, Xiong, Yao, Hansson, Thomas G
Published in Journal of medicinal chemistry (23.09.2021)
Published in Journal of medicinal chemistry (23.09.2021)
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Potent and Orally Bioavailable Inverse Agonists of RORγt Resulting from Structure-Based Design
Narjes, Frank, Xue, Yafeng, von Berg, Stefan, Malmberg, Jesper, Llinas, Antonio, Olsson, Roine I, Jirholt, Johan, Grindebacke, Hanna, Leffler, Agnes, Hossain, Nafizal, Lepistö, Matti, Thunberg, Linda, Leek, Hanna, Aagaard, Anna, McPheat, Jane, Hansson, Eva L, Bäck, Elisabeth, Tångefjord, Stefan, Chen, Rongfeng, Xiong, Yao, Hongbin, Ge, Hansson, Thomas G
Published in Journal of medicinal chemistry (13.09.2018)
Published in Journal of medicinal chemistry (13.09.2018)
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Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper 17 (T(H)17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor ROR gamma
Olsson, Roine I., Xue, Yafeng, von Berg, Stefan, Aagaard, Anna, McPheat, Jane, Hansson, Eva L., Bernstrom, Jenny, Hansson, Pia, Jirholt, Johan, Grindebacke, Hanna, Leffler, Agnes, Chen, Rongfeng, Xiong, Yao, Ge, Hongbin, Hansson, Thomas G., Narjes, Frank
Published in ChemMedChem (19.01.2016)
Published in ChemMedChem (19.01.2016)
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Retinoid-related orphan receptor γ (RORγ) adult induced knockout mice develop lymphoblastic lymphoma
Liljevald, Maria, Rehnberg, Maria, Söderberg, Magnus, Ramnegård, Marie, Börjesson, Jenny, Luciani, Donatella, Krutrök, Nina, Brändén, Lena, Johansson, Camilla, Xu, Xiufeng, Bjursell, Mikael, Sjögren, Anna-Karin, Hornberg, Jorrit, Andersson, Ulf, Keeling, David, Jirholt, Johan
Published in Autoimmunity reviews (01.11.2016)
Published in Autoimmunity reviews (01.11.2016)
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Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper 17 (TH17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor RORγ
Olsson, Roine I., Xue, Yafeng, von Berg, Stefan, Aagaard, Anna, McPheat, Jane, Hansson, Eva L., Bernström, Jenny, Hansson, Pia, Jirholt, Johan, Grindebacke, Hanna, Leffler, Agnes, Chen, Rongfeng, Xiong, Yao, Ge, Hongbin, Hansson, Thomas G., Narjes, Frank
Published in ChemMedChem (19.01.2016)
Published in ChemMedChem (19.01.2016)
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Discovery of Potent and Orally Bioavailable Inverse Agonists of the Retinoic Acid Receptor-Related Orphan Receptor C2
von Berg, Stefan, Xue, Yafeng, Collins, Mia, Llinas, Antonio, Olsson, Roine I, Halvarsson, Torbjörn, Lindskog, Maria, Malmberg, Jesper, Jirholt, Johan, Krutrök, Nina, Ramnegård, Marie, Brännström, Marie, Lundqvist, Anders, Lepistö, Matti, Aagaard, Anna, McPheat, Jane, Hansson, Eva L, Chen, Rongfeng, Xiong, Yao, Hansson, Thomas G, Narjes, Frank
Published in ACS medicinal chemistry letters (13.06.2019)
Published in ACS medicinal chemistry letters (13.06.2019)
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Back Cover: Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper17 (TH17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor ROR[gamma]
Olsson, Roine I, Xue, Yafeng, vonBerg, Stefan, Aagaard, Anna, McPheat, Jane, Hansson, Eva L, Bernstrom, Jenny, Hansson, Pia, Jirholt, Johan, Grindebacke, Hanna, Leffler, Agnes, Chen, Rongfeng, Xiong, Yao, Ge, Hongbin, Hansson, Thomas G, Narjes, Frank
Published in ChemMedChem (01.01.2016)
Published in ChemMedChem (01.01.2016)
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Journal Article
Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper17 (TH17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor ROR[gamma]
Olsson, Roine I, Xue, Yafeng, vonBerg, Stefan, Aagaard, Anna, McPheat, Jane, Hansson, Eva L, Bernstrom, Jenny, Hansson, Pia, Jirholt, Johan, Grindebacke, Hanna, Leffler, Agnes, Chen, Rongfeng, Xiong, Yao, Ge, Hongbin, Hansson, Thomas G, Narjes, Frank
Published in ChemMedChem (01.01.2016)
Published in ChemMedChem (01.01.2016)
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Back Cover: Benzoxazepines Achieve Potent Suppression of IL-17 Release in Human T-Helper 17 (TH17) Cells through an Induced-Fit Binding Mode to the Nuclear Receptor RORγ (ChemMedChem 2/2016)
Olsson, Roine I., Xue, Yafeng, von Berg, Stefan, Aagaard, Anna, McPheat, Jane, Hansson, Eva L., Bernström, Jenny, Hansson, Pia, Jirholt, Johan, Grindebacke, Hanna, Leffler, Agnes, Chen, Rongfeng, Xiong, Yao, Ge, Hongbin, Hansson, Thomas G., Narjes, Frank
Published in ChemMedChem (01.01.2016)
Published in ChemMedChem (01.01.2016)
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4-Aminobutyrate Aminotransferase
Jirholt, Johan, Åsling, Bengt, Hammond, Paul, Davidson, Geoffrey, Knutsson, Mikael, Walentinsson, Anna, Jensen, Jörgen M, Lehmann, Anders, Agreus, Lars, Lagerström-Fermer, Maria
Published in PloS one (28.04.2011)
Published in PloS one (28.04.2011)
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Identification of Genes Controlling Collagen-Induced Arthritis in Mice: Striking Homology with Susceptibility Loci Previously Identified in the Rat
Yang, Hai-Tao, Jirholt, Johan, Svensson, Lars, Sundvall, Mats, Jansson, Liselotte, Pettersson, Ulf, Holmdahl, Rikard
Published in The Journal of immunology (1950) (01.09.1999)
Published in The Journal of immunology (1950) (01.09.1999)
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Identification of murine loci associated with susceptibility to chronic experimental autoimmune encephalomyelitis
Sundvall, Mats, Jirholt, Johan, Yang, Hai-Tao, Jansson, Liselotte, Engström, Åke, Pettersson, Ulf, Holmdahl, Rikard
Published in Nature genetics (01.07.1995)
Published in Nature genetics (01.07.1995)
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Genetic linkage analysis of collagen‐induced arthritis in the mouse
Jirholt, Johan, Cook, Andrew, Emahazion, Tesfai, Sundvall, Mats, Jansson, Liselotte, Nordquist, Niklas, Pettersson, Ulf, Holmdahl, Rikard
Published in European journal of immunology (01.10.1998)
Published in European journal of immunology (01.10.1998)
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Screening of several H-2 congenic mouse strains identified H-2(q) mice as highly susceptible to MOG-induced EAE with minimal adjuvant requirement
Abdul-Majid, K B, Jirholt, J, Stadelmann, C, Stefferl, A, Kjellén, P, Wallström, E, Holmdahl, R, Lassmann, H, Olsson, T, Harris, R A
Published in Journal of neuroimmunology (01.11.2000)
Published in Journal of neuroimmunology (01.11.2000)
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Suggestive Evidence for Association of Human Chromosome 18q12-q21 and Its Orthologue on Rat and Mouse Chromosome 18 With Several Autoimmune Diseases
MERRIMAN, Tony R, CORDELL, Heather J, WORDSWORTH, Paul, SHATFORD, Jane, LAVAL, Steve, JIRHOLT, Johan, HOLMDAHL, Rikard, THEOFILOPOULOS, Argyrios N, KONO, Dwight H, TUOMILEHTO, Jaakko, TUOMILEHTO-WOLF, Eva, BUZZETTI, Raffaella, EAVES, Lain A, MARROSU, Maria Giovanna, UNDLIEN, Dag E, RØNNINGEN, Kjersti S, IONESCO-TIRGOVISTE, C, SHIELD, Julian P, POCIOT, Fleming, NERUP, Jorn, JACOB, Chaim O, POLYCHRONAKOS, Constantin, BAIN, Steve C, DANOY, Patrick A, TODD, John A, CORADDU, Francesca, BARBER, Rachael, CUCCA, Francesco, BROADLEY, Simon, SAWCER, Stephen, COMPSTON, Alastair
Published in Diabetes (New York, N.Y.) (01.01.2001)
Published in Diabetes (New York, N.Y.) (01.01.2001)
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Screening of several H-2 congenic mouse strains identified H-2q mice as highly susceptible to MOG-induced EAE with minimal adjuvant requirement
Abdul-Majid, Khairul-Bariah, Jirholt, Johan, Stadelmann, Christine, Stefferl, Andreas, Kjellén, Peter, Wallström, Erik, Holmdahl, Rikard, Lassmann, Hans, Olsson, Tomas, Harris, Robert A.
Published in Journal of neuroimmunology (01.11.2000)
Published in Journal of neuroimmunology (01.11.2000)
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